|
2006-12-18 |
2006-12-15 |
V
Vente
|
Rubinstein Linda M
VP & Chief Financial Officer
Dirigeant
|
4 750
-100.0%
12,78
60 705 USD
|
4 750
-100.0%
|
12,78
|
60 705 USD
|
|
|
2006-12-18 |
2006-12-15 |
V
Vente
|
Rubinstein Linda M
VP & Chief Financial Officer
Dirigeant
|
4 000
-100.0%
12,78
51 120 USD
|
4 000
-100.0%
|
12,78
|
51 120 USD
|
|
|
2006-12-18 |
2006-12-14 |
V
Vente
|
Rubinstein Linda M
VP & Chief Financial Officer
Dirigeant
|
9 558
-100.0%
12,65
120 909 USD
|
9 558
-100.0%
|
12,65
|
120 909 USD
|
|
|
2006-12-15 |
2006-12-13 |
V
Vente
|
Rubinstein Linda M
VP & Chief Financial Officer
Dirigeant
|
7 812
-100.0%
12,66
98 914 USD
|
7 812
-100.0%
|
12,66
|
98 914 USD
|
|
|
2006-12-15 |
2006-12-13 |
V
Vente
|
Rubinstein Linda M
VP & Chief Financial Officer
Dirigeant
|
6 067
-100.0%
12,66
76 819 USD
|
6 067
-100.0%
|
12,66
|
76 819 USD
|
|
|
2006-12-15 |
2006-12-13 |
V
Vente
|
Rubinstein Linda M
VP & Chief Financial Officer
Dirigeant
|
7 812
-100.0%
12,66
98 914 USD
|
7 812
-100.0%
|
12,66
|
98 914 USD
|
|
|
2006-12-15 |
2006-12-13 |
V
Vente
|
Rubinstein Linda M
VP & Chief Financial Officer
Dirigeant
|
50 000
-100.0%
12,66
633 090 USD
|
50 000
-100.0%
|
12,66
|
633 090 USD
|
|
|
2006-12-13 |
2006-12-12 |
V
Vente
|
Omead Ostadan
VP, Marketing
Dirigeant
|
15 000
-100.0%
12,77
191 505 USD
|
15 000
-100.0%
|
12,77
|
191 505 USD
|
|
|
2006-12-13 |
2006-12-12 |
V
Vente
|
Lundberg Peter
VP & Chief Technical Officer
Dirigeant
|
1 000
-100.0%
12,86
12 860 USD
|
1 000
-100.0%
|
12,86
|
12 860 USD
|
|
|
2006-12-12 |
2006-12-11 |
V
Vente
|
Lundberg Peter
VP & Chief Technical Officer
Dirigeant
|
3 250
-100.0%
12,95
42 088 USD
|
3 250
-100.0%
|
12,95
|
42 088 USD
|
|
|
2006-12-12 |
2006-12-11 |
V
Vente
|
Lundberg Peter
VP & Chief Technical Officer
Dirigeant
|
3 000
-100.0%
12,95
38 850 USD
|
3 000
-100.0%
|
12,95
|
38 850 USD
|
|
|
2006-12-12 |
2006-12-11 |
V
Vente
|
Lundberg Peter
VP & Chief Technical Officer
Dirigeant
|
8 000
-100.0%
12,91
103 312 USD
|
8 000
-100.0%
|
12,91
|
103 312 USD
|
|
|
2006-12-12 |
2006-12-11 |
V
Vente
|
Lundberg Peter
VP & Chief Technical Officer
Dirigeant
|
4 500
-100.0%
12,92
58 132 USD
|
4 500
-100.0%
|
12,92
|
58 132 USD
|
|
|
2006-12-12 |
2006-12-11 |
V
Vente
|
Lundberg Peter
VP & Chief Technical Officer
Dirigeant
|
1 500
-100.0%
12,96
19 440 USD
|
1 500
-100.0%
|
12,96
|
19 440 USD
|
|
|
2006-12-12 |
2006-12-11 |
V
Vente
|
Lundberg Peter
VP & Chief Technical Officer
Dirigeant
|
2 500
-100.0%
12,97
32 425 USD
|
2 500
-100.0%
|
12,97
|
32 425 USD
|
|
|
2006-12-12 |
2006-12-11 |
V
Vente
|
Lundberg Peter
VP & Chief Technical Officer
Dirigeant
|
8 000
-100.0%
12,93
103 425 USD
|
8 000
-100.0%
|
12,93
|
103 425 USD
|
|
|
2006-12-12 |
2006-12-11 |
V
Vente
|
Lundberg Peter
VP & Chief Technical Officer
Dirigeant
|
2 000
-100.0%
12,93
25 860 USD
|
2 000
-100.0%
|
12,93
|
25 860 USD
|
|
|
2006-12-12 |
2006-12-11 |
V
Vente
|
Lundberg Peter
VP & Chief Technical Officer
Dirigeant
|
2 500
-100.0%
12,97
32 425 USD
|
2 500
-100.0%
|
12,97
|
32 425 USD
|
|
|
2006-08-03 |
2006-07-17 |
V
Vente
|
SIEGEL BROCK M
Chief Operating Officer
Dirigeant
|
7
-0.0%
8,75
61 USD
|
7
-0.0%
|
8,75
|
61 USD
|
|
|
2006-01-23 |
2006-01-19 |
A
Achat
|
Amadeus Capital Partners LTD
Actionnaire important
|
11 538
+9.0%
6,50
74 997 USD
|
11 538
+9.0%
|
6,50
|
74 997 USD
|
|
|
2006-01-23 |
2006-01-19 |
A
Achat
|
Amadeus Capital Partners LTD
Actionnaire important
|
3 846
+9.0%
6,50
24 999 USD
|
3 846
+9.0%
|
6,50
|
24 999 USD
|
|
|
2006-01-23 |
2006-01-19 |
A
Achat
|
Amadeus Capital Partners LTD
Actionnaire important
|
80 769
+9.0%
6,50
524 999 USD
|
80 769
+9.0%
|
6,50
|
524 999 USD
|
|
|
2006-01-23 |
2006-01-19 |
A
Achat
|
Amadeus Capital Partners LTD
Actionnaire important
|
115 385
+9.0%
6,50
750 003 USD
|
115 385
+9.0%
|
6,50
|
750 003 USD
|
|
|
2006-01-23 |
2006-01-19 |
A
Achat
|
HAUSER HERMANN
Administrateur non-exécutif
|
11 538
+9.0%
6,50
74 997 USD
|
11 538
+9.0%
|
6,50
|
74 997 USD
|
|
|
2006-01-23 |
2006-01-19 |
A
Achat
|
HAUSER HERMANN
Administrateur non-exécutif
|
3 846
+9.0%
6,50
24 999 USD
|
3 846
+9.0%
|
6,50
|
24 999 USD
|
|
|
2006-01-23 |
2006-01-19 |
A
Achat
|
HAUSER HERMANN
Administrateur non-exécutif
|
80 769
+9.0%
6,50
524 999 USD
|
80 769
+9.0%
|
6,50
|
524 999 USD
|
|
|
2006-01-23 |
2006-01-19 |
A
Achat
|
HAUSER HERMANN
Administrateur non-exécutif
|
115 385
+9.0%
6,50
750 003 USD
|
115 385
+9.0%
|
6,50
|
750 003 USD
|
|
|
2006-01-23 |
2006-01-19 |
A
Achat
|
Amadeus Capital Partners LTD
Actionnaire important
|
173 077
+9.0%
6,50
1 125 001 USD
|
173 077
+9.0%
|
6,50
|
1 125 001 USD
|
|
|
2006-01-23 |
2006-01-19 |
A
Achat
|
HAUSER HERMANN
Administrateur non-exécutif
|
173 077
+9.0%
6,50
1 125 001 USD
|
173 077
+9.0%
|
6,50
|
1 125 001 USD
|
|
|
2006-01-19 |
2006-01-17 |
V
Vente
|
SCHRODER VENTURE MANAGERS LTD
Actionnaire important
|
3 763
-11.5%
11,34
42 672 USD
|
3 763
-11.5%
|
11,34
|
42 672 USD
|
|
|
2006-01-19 |
2006-01-17 |
V
Vente
|
SCHRODER VENTURE MANAGERS LTD
Actionnaire important
|
30 041
-11.5%
11,34
340 665 USD
|
30 041
-11.5%
|
11,34
|
340 665 USD
|
|
|
2006-01-19 |
2006-01-17 |
V
Vente
|
SCHRODER VENTURE MANAGERS LTD
Actionnaire important
|
7 014
-11.5%
11,34
79 539 USD
|
7 014
-11.5%
|
11,34
|
79 539 USD
|
|
|
2006-01-19 |
2006-01-17 |
V
Vente
|
SCHRODER VENTURE MANAGERS LTD
Actionnaire important
|
27 683
-11.5%
11,34
313 925 USD
|
27 683
-11.5%
|
11,34
|
313 925 USD
|
|
|
2006-01-19 |
2006-01-17 |
V
Vente
|
SCHRODER VENTURE MANAGERS LTD
Actionnaire important
|
103 876
-11.5%
11,34
1 177 954 USD
|
103 876
-11.5%
|
11,34
|
1 177 954 USD
|
|
|
2006-01-19 |
2006-01-17 |
V
Vente
|
SCHRODER VENTURE MANAGERS LTD
Actionnaire important
|
243 901
-11.5%
11,34
2 765 837 USD
|
243 901
-11.5%
|
11,34
|
2 765 837 USD
|
|
|
2005-07-14 |
2005-07-12 |
A
Achat
|
OXFORD BIOSCIENCE PARTNERS IV LP
Actionnaire important
|
5 464
+22.1%
4,00
21 856 USD
|
5 464
+22.1%
|
4,00
|
21 856 USD
|
|
|
2005-07-14 |
2005-07-12 |
A
Achat
|
OXFORD BIOSCIENCE PARTNERS IV LP
Actionnaire important
|
544 536
+22.1%
4,00
2 178 144 USD
|
544 536
+22.1%
|
4,00
|
2 178 144 USD
|
|
|
2005-07-14 |
2005-07-12 |
A
Achat
|
HAUSER HERMANN
Administrateur non-exécutif
|
23 078
+22.1%
4,00
92 312 USD
|
23 078
+22.1%
|
4,00
|
92 312 USD
|
|
|
2005-07-14 |
2005-07-12 |
A
Achat
|
HAUSER HERMANN
Administrateur non-exécutif
|
7 693
+22.1%
4,00
30 772 USD
|
7 693
+22.1%
|
4,00
|
30 772 USD
|
|
|
2005-07-14 |
2005-07-12 |
A
Achat
|
HAUSER HERMANN
Administrateur non-exécutif
|
161 543
+22.1%
4,00
646 172 USD
|
161 543
+22.1%
|
4,00
|
646 172 USD
|
|
|
2005-07-14 |
2005-07-12 |
A
Achat
|
HAUSER HERMANN
Administrateur non-exécutif
|
230 775
+22.1%
4,00
923 100 USD
|
230 775
+22.1%
|
4,00
|
923 100 USD
|
|
|
2005-07-14 |
2005-07-12 |
A
Achat
|
HAUSER HERMANN
Administrateur non-exécutif
|
346 163
+22.1%
4,00
1 384 652 USD
|
346 163
+22.1%
|
4,00
|
1 384 652 USD
|
|
|
2005-07-14 |
2005-07-12 |
A
Achat
|
Abingworth Management LTD
Actionnaire important
|
4 637
+31.1%
4,00
18 548 USD
|
4 637
+31.1%
|
4,00
|
18 548 USD
|
|
|
2005-07-14 |
2005-07-12 |
A
Achat
|
Abingworth Management LTD
Actionnaire important
|
106 399
+31.1%
4,00
425 596 USD
|
106 399
+31.1%
|
4,00
|
425 596 USD
|
|
|
2005-07-14 |
2005-07-12 |
A
Achat
|
Abingworth Management LTD
Actionnaire important
|
177 625
+31.1%
4,00
710 500 USD
|
177 625
+31.1%
|
4,00
|
710 500 USD
|
|
|
2005-07-14 |
2005-07-12 |
A
Achat
|
Abingworth Management LTD
Actionnaire important
|
290 978
+31.1%
4,00
1 163 912 USD
|
290 978
+31.1%
|
4,00
|
1 163 912 USD
|
|
|
2005-07-14 |
2005-07-12 |
A
Achat
|
Abingworth Management LTD
Actionnaire important
|
250 000
+68.8%
4,00
1 000 000 USD
|
250 000
+68.8%
|
4,00
|
1 000 000 USD
|
|
|
2005-07-14 |
2005-07-12 |
A
Achat
|
Amadeus Capital Partners LTD
Actionnaire important
|
23 078
+22.1%
4,00
92 312 USD
|
23 078
+22.1%
|
4,00
|
92 312 USD
|
|
|
2005-07-14 |
2005-07-12 |
A
Achat
|
Amadeus Capital Partners LTD
Actionnaire important
|
7 693
+22.1%
4,00
30 772 USD
|
7 693
+22.1%
|
4,00
|
30 772 USD
|
|
|
2005-07-14 |
2005-07-12 |
A
Achat
|
Amadeus Capital Partners LTD
Actionnaire important
|
161 543
+22.1%
4,00
646 172 USD
|
161 543
+22.1%
|
4,00
|
646 172 USD
|
|
|
2005-07-14 |
2005-07-12 |
A
Achat
|
Amadeus Capital Partners LTD
Actionnaire important
|
230 775
+22.1%
4,00
923 100 USD
|
230 775
+22.1%
|
4,00
|
923 100 USD
|
|
|
2005-07-14 |
2005-07-12 |
A
Achat
|
Amadeus Capital Partners LTD
Actionnaire important
|
346 163
+22.1%
4,00
1 384 652 USD
|
346 163
+22.1%
|
4,00
|
1 384 652 USD
|
|
|
2005-04-25 |
2005-04-22 |
A
Achat
|
SCHRODER VENTURE MANAGERS LTD
Actionnaire important
|
5 102
0,00
0 USD
|
5 102
|
0,00
|
0 USD
|
|
|
2005-04-25 |
2005-04-22 |
A
Achat
|
SCHRODER VENTURE MANAGERS LTD
Actionnaire important
|
40 736
0,00
0 USD
|
40 736
|
0,00
|
0 USD
|
|
|
2005-04-25 |
2005-04-22 |
A
Achat
|
SCHRODER VENTURE MANAGERS LTD
Actionnaire important
|
9 511
0,00
0 USD
|
9 511
|
0,00
|
0 USD
|
|
|
2005-04-25 |
2005-04-22 |
A
Achat
|
SCHRODER VENTURE MANAGERS LTD
Actionnaire important
|
37 538
0,00
0 USD
|
37 538
|
0,00
|
0 USD
|
|
|
2005-04-25 |
2005-04-22 |
A
Achat
|
SCHRODER VENTURE MANAGERS LTD
Actionnaire important
|
140 857
0,00
0 USD
|
140 857
|
0,00
|
0 USD
|
|
|
2005-04-25 |
2005-04-22 |
A
Achat
|
SCHRODER VENTURE MANAGERS LTD
Actionnaire important
|
330 730
0,00
0 USD
|
330 730
|
0,00
|
0 USD
|
|
