|
2021-11-12 |
2021-11-10 |
V
Vente
|
Van Hove Caroline F.
Executive Chairman
Administrateur non-exécutif
|
6 087
-4.0%
5,67
34 513 USD
|
6 087
-4.0%
|
5,67
|
34 513 USD
|
|
|
2021-11-12 |
2021-11-10 |
V
Vente
|
Menezes Ronald
President and CEO
Administrateur exécutif
|
78 498
-15.5%
5,67
445 084 USD
|
78 498
-15.5%
|
5,67
|
445 084 USD
|
|
|
2021-10-07 |
2021-10-05 |
V
Vente
|
Bennett Oliver Christian
GC & Chief Compliance Officer
Dirigeant
|
3 615
-4.5%
5,56
20 099 USD
|
3 615
-4.5%
|
5,56
|
20 099 USD
|
|
|
2021-08-12 |
2021-08-12 |
A
Achat
|
Schmidt Andrew C
Chief Financial Officer
Dirigeant
|
1 449
+3.0%
6,89
9 976 USD
|
1 449
+3.0%
|
6,89
|
9 976 USD
|
|
|
2021-04-08 |
2021-04-06 |
V
Vente
|
MILLER VALERIE J
VP, Controller and Interim CFO
Dirigeant
|
1 508
-2.3%
7,13
10 751 USD
|
1 508
-2.3%
|
7,13
|
10 751 USD
|
|
|
2021-03-25 |
2021-03-12 |
V
Vente
|
MILLER VALERIE J
VP, Controller and Interim CFO
Dirigeant
|
1 582
-2.4%
7,49
11 849 USD
|
1 582
-2.4%
|
7,49
|
11 849 USD
|
|
|
2021-02-03 |
2021-02-02 |
V
Vente
|
Little Paul Sean
Chief Financial Officer
Dirigeant
|
4 123
-3.0%
4,91
20 256 USD
|
4 123
-3.0%
|
4,91
|
20 256 USD
|
|
|
2021-01-22 |
2021-01-20 |
V
Vente
|
Bennett Oliver Christian
GC & Chief Compliance Officer
Dirigeant
|
4 399
-5.9%
4,49
19 752 USD
|
4 399
-5.9%
|
4,49
|
19 752 USD
|
|
|
2021-01-20 |
2021-01-13 |
V
Vente
|
Van Hove Caroline F.
Administrateur non-exécutif
|
1 973
-1.4%
4,71
9 301 USD
|
1 973
-1.4%
|
4,71
|
9 301 USD
|
|
|
2020-02-20 |
2020-02-20 |
VP
Vente planifiée
|
Nugent Jeffrey M
Chairman of the Board and CEO
Administrateur exécutif
|
63 557
-23.2%
5,91
375 368 USD
|
63 557
-23.2%
|
5,91
|
375 368 USD
|
|
|
2020-02-20 |
2020-02-19 |
VP
Vente planifiée
|
Nugent Jeffrey M
Chairman of the Board and CEO
Administrateur exécutif
|
53 513
-16.4%
5,93
317 113 USD
|
53 513
-16.4%
|
5,93
|
317 113 USD
|
|
|
2020-02-20 |
2020-02-18 |
VP
Vente planifiée
|
Nugent Jeffrey M
Chairman of the Board and CEO
Administrateur exécutif
|
16 506
-4.8%
6,00
98 960 USD
|
16 506
-4.8%
|
6,00
|
98 960 USD
|
|
|
2019-06-11 |
2019-06-07 |
A
Achat
|
Sullivan Keith J
|
20 869
+11.4%
5,75
119 997 USD
|
20 869
+11.4%
|
5,75
|
119 997 USD
|
|
|
2019-06-11 |
2019-06-07 |
A
Achat
|
Little Paul Sean
Chief Financial Officer
|
17 391
+22.4%
5,75
99 998 USD
|
17 391
+22.4%
|
5,75
|
99 998 USD
|
|
|
2019-06-11 |
2019-06-07 |
A
Achat
|
OBOYLE KEVIN C
|
8 696
+19.3%
5,75
50 002 USD
|
8 696
+19.3%
|
5,75
|
50 002 USD
|
|
|
2018-11-08 |
2018-11-06 |
VP
Vente planifiée
|
Haines Timothy
Administrateur non-exécutif
|
81 137
-3.3%
21,60
1 752 559 USD
|
81 137
-3.3%
|
21,60
|
1 752 559 USD
|
|
|
2018-11-08 |
2018-11-06 |
VP
Vente planifiée
|
Haines Timothy
Administrateur non-exécutif
|
8 514
-0.3%
21,13
179 901 USD
|
8 514
-0.3%
|
21,13
|
179 901 USD
|
|
|
2018-09-05 |
2018-08-31 |
V
Vente
|
Nugent Jeffrey M
Chairman of the Board and CEO
Administrateur exécutif
|
1 852
-0.6%
24,90
46 115 USD
|
1 852
-0.6%
|
24,90
|
46 115 USD
|
|
|
2018-05-09 |
2018-05-07 |
A
Achat
|
Haines Timothy
Administrateur non-exécutif
|
281 482
+12.8%
13,50
3 800 007 USD
|
281 482
+12.8%
|
13,50
|
3 800 007 USD
|
|
|
2018-05-09 |
2018-05-07 |
A
Achat
|
Abingworth LLP
|
281 482
+12.8%
13,50
3 800 007 USD
|
281 482
+12.8%
|
13,50
|
3 800 007 USD
|
|
|
2018-05-09 |
2018-05-07 |
A
Achat
|
SCHAISON PHILIPPE
Administrateur non-exécutif
|
7 407
+24.4%
13,50
99 995 USD
|
7 407
+24.4%
|
13,50
|
99 995 USD
|
|
|
2018-05-09 |
2018-05-07 |
A
Achat
|
Williams Patrick F.
Chief Financial Officer & SVP
Dirigeant
|
7 408
+14.8%
13,50
100 008 USD
|
7 408
+14.8%
|
13,50
|
100 008 USD
|
|
|
2018-05-09 |
2018-05-07 |
A
Achat
|
Nugent Jeffrey M
Chairman of the Board and CEO
Administrateur exécutif
|
1 852
+0.6%
13,50
25 002 USD
|
1 852
+0.6%
|
13,50
|
25 002 USD
|
|
|
2018-05-09 |
2018-05-07 |
A
Achat
|
Sullivan Keith J
Administrateur non-exécutif
|
7 407
+6.5%
13,50
99 995 USD
|
7 407
+6.5%
|
13,50
|
99 995 USD
|
|
|
2018-05-09 |
2018-05-07 |
A
Achat
|
GREER R SCOTT
Administrateur non-exécutif
|
11 111
+26.7%
13,50
149 999 USD
|
11 111
+26.7%
|
13,50
|
149 999 USD
|
|
|
2018-05-09 |
2018-05-07 |
A
Achat
|
OBOYLE KEVIN C
Administrateur non-exécutif
|
7 407
+23.5%
13,50
99 995 USD
|
7 407
+23.5%
|
13,50
|
99 995 USD
|
|
|
2015-10-13 |
2015-10-12 |
V
Vente
|
ORBIMED ADVISORS LLC
Actionnaire important
|
2 785
-14.0%
5,98
16 654 USD
|
2 785
-14.0%
|
5,98
|
16 654 USD
|
|
|
2015-10-13 |
2015-10-12 |
V
Vente
|
ORBIMED ADVISORS LLC
Actionnaire important
|
285 106
-13.9%
5,98
1 704 934 USD
|
285 106
-13.9%
|
5,98
|
1 704 934 USD
|
|
|
2015-10-09 |
2015-10-09 |
V
Vente
|
ORBIMED ADVISORS LLC
Actionnaire important
|
2 041
-9.3%
7,03
14 348 USD
|
2 041
-9.3%
|
7,03
|
14 348 USD
|
|
|
2015-10-09 |
2015-10-09 |
V
Vente
|
ORBIMED ADVISORS LLC
Actionnaire important
|
210 668
-9.3%
7,03
1 480 996 USD
|
210 668
-9.3%
|
7,03
|
1 480 996 USD
|
|
|
2015-10-09 |
2015-10-08 |
V
Vente
|
ORBIMED ADVISORS LLC
Actionnaire important
|
3 837
-14.9%
7,24
27 780 USD
|
3 837
-14.9%
|
7,24
|
27 780 USD
|
|
|
2015-10-09 |
2015-10-08 |
V
Vente
|
ORBIMED ADVISORS LLC
Actionnaire important
|
396 163
-14.9%
7,24
2 868 220 USD
|
396 163
-14.9%
|
7,24
|
2 868 220 USD
|
|
|
2015-10-09 |
2015-10-07 |
V
Vente
|
ORBIMED ADVISORS LLC
Actionnaire important
|
454
-1.7%
7,36
3 341 USD
|
454
-1.7%
|
7,36
|
3 341 USD
|
|
|
2015-10-09 |
2015-10-07 |
V
Vente
|
ORBIMED ADVISORS LLC
Actionnaire important
|
53 446
-2.0%
7,36
393 363 USD
|
53 446
-2.0%
|
7,36
|
393 363 USD
|
|
|
2015-10-06 |
2015-10-06 |
V
Vente
|
ORBIMED ADVISORS LLC
Actionnaire important
|
59
-0.2%
7,80
460 USD
|
59
-0.2%
|
7,80
|
460 USD
|
|
|
2015-10-06 |
2015-10-06 |
V
Vente
|
ORBIMED ADVISORS LLC
Actionnaire important
|
6 941
-0.3%
7,80
54 140 USD
|
6 941
-0.3%
|
7,80
|
54 140 USD
|
|
|
2015-10-06 |
2015-10-05 |
V
Vente
|
ORBIMED ADVISORS LLC
Actionnaire important
|
1 163
-4.2%
8,19
9 525 USD
|
1 163
-4.2%
|
8,19
|
9 525 USD
|
|
|
2015-10-06 |
2015-10-05 |
V
Vente
|
ORBIMED ADVISORS LLC
Actionnaire important
|
136 937
-4.8%
8,19
1 121 514 USD
|
136 937
-4.8%
|
8,19
|
1 121 514 USD
|
|
|
2015-10-06 |
2015-10-02 |
V
Vente
|
ORBIMED ADVISORS LLC
Actionnaire important
|
403
-1.4%
10,34
4 167 USD
|
403
-1.4%
|
10,34
|
4 167 USD
|
|
|
2015-10-06 |
2015-10-02 |
V
Vente
|
ORBIMED ADVISORS LLC
Actionnaire important
|
47 497
-1.6%
10,34
491 119 USD
|
47 497
-1.6%
|
10,34
|
491 119 USD
|
|
|
2015-10-01 |
2015-10-01 |
V
Vente
|
ORBIMED ADVISORS LLC
Actionnaire important
|
400
-1.4%
10,34
4 136 USD
|
400
-1.4%
|
10,34
|
4 136 USD
|
|
|
2015-10-01 |
2015-10-01 |
V
Vente
|
ORBIMED ADVISORS LLC
Actionnaire important
|
47 100
-1.6%
10,34
487 014 USD
|
47 100
-1.6%
|
10,34
|
487 014 USD
|
|
|
2015-10-01 |
2015-09-30 |
V
Vente
|
ORBIMED ADVISORS LLC
Actionnaire important
|
369
-1.3%
10,17
3 753 USD
|
369
-1.3%
|
10,17
|
3 753 USD
|
|
|
2015-10-01 |
2015-09-30 |
V
Vente
|
ORBIMED ADVISORS LLC
Actionnaire important
|
43 471
-1.5%
10,17
442 100 USD
|
43 471
-1.5%
|
10,17
|
442 100 USD
|
|
|
2015-10-01 |
2015-09-29 |
V
Vente
|
ORBIMED ADVISORS LLC
Actionnaire important
|
89
-0.3%
10,08
897 USD
|
89
-0.3%
|
10,08
|
897 USD
|
|
|
2015-10-01 |
2015-09-29 |
V
Vente
|
ORBIMED ADVISORS LLC
Actionnaire important
|
10 469
-0.3%
10,08
105 528 USD
|
10 469
-0.3%
|
10,08
|
105 528 USD
|
|
|
2015-09-28 |
2015-09-28 |
V
Vente
|
ORBIMED ADVISORS LLC
Actionnaire important
|
89
-0.3%
10,30
917 USD
|
89
-0.3%
|
10,30
|
917 USD
|
|
|
2015-09-28 |
2015-09-28 |
V
Vente
|
ORBIMED ADVISORS LLC
Actionnaire important
|
10 513
-0.3%
10,30
108 284 USD
|
10 513
-0.3%
|
10,30
|
108 284 USD
|
|
|
2015-09-28 |
2015-09-25 |
V
Vente
|
ORBIMED ADVISORS LLC
Actionnaire important
|
311
-1.1%
11,07
3 443 USD
|
311
-1.1%
|
11,07
|
3 443 USD
|
|
|
2015-09-28 |
2015-09-25 |
V
Vente
|
ORBIMED ADVISORS LLC
Actionnaire important
|
66 489
-2.2%
11,07
736 033 USD
|
66 489
-2.2%
|
11,07
|
736 033 USD
|
|
|
2015-09-28 |
2015-09-25 |
V
Vente
|
ORBIMED ADVISORS LLC
Actionnaire important
|
800
-2.7%
10,07
8 056 USD
|
800
-2.7%
|
10,07
|
8 056 USD
|
|
|
2015-09-28 |
2015-09-25 |
V
Vente
|
ORBIMED ADVISORS LLC
Actionnaire important
|
64 400
-2.0%
10,07
648 508 USD
|
64 400
-2.0%
|
10,07
|
648 508 USD
|
|
|
2015-09-28 |
2015-09-24 |
V
Vente
|
ORBIMED ADVISORS LLC
Actionnaire important
|
8 152
-0.3%
11,00
89 672 USD
|
8 152
-0.3%
|
11,00
|
89 672 USD
|
|
|
2015-09-28 |
2015-09-24 |
V
Vente
|
ORBIMED ADVISORS LLC
Actionnaire important
|
148
-0.5%
11,00
1 628 USD
|
148
-0.5%
|
11,00
|
1 628 USD
|
|
|
2015-09-28 |
2015-09-24 |
V
Vente
|
ORBIMED ADVISORS LLC
Actionnaire important
|
6
-0.0%
9,78
59 USD
|
6
-0.0%
|
9,78
|
59 USD
|
|
|
2014-11-03 |
2014-10-29 |
A
Achat
|
Haines Timothy
Administrateur non-exécutif
Actionnaire important
|
495 000
+29.0%
15,00
7 425 000 USD
|
495 000
+29.0%
|
15,00
|
7 425 000 USD
|
|
|
2014-10-31 |
2014-10-29 |
A
Achat
|
Abingworth LLP
Actionnaire important
|
495 000
+29.0%
15,00
7 425 000 USD
|
495 000
+29.0%
|
15,00
|
7 425 000 USD
|
|
