|
2011-12-05 |
2011-12-01 |
V
Vente
|
Berrey M Michelle
Chief Medical Officer
Dirigeant
|
3 126
-100.0%
130,33
407 412 USD
|
3 126
-100.0%
|
130,33
|
407 412 USD
|
|
|
2011-12-05 |
2011-12-01 |
V
Vente
|
Berrey M Michelle
Chief Medical Officer
Dirigeant
|
3 126
-100.0%
130,33
407 412 USD
|
3 126
-100.0%
|
130,33
|
407 412 USD
|
|
|
2011-11-07 |
2011-11-01 |
V
Vente
|
OTTO MICHAEL J.
Chief Scientific Officer
Dirigeant
|
17 500
-100.0%
74,56
1 304 800 USD
|
17 500
-100.0%
|
74,56
|
1 304 800 USD
|
|
|
2011-11-03 |
2011-11-01 |
V
Vente
|
Berrey M Michelle
Chief Medical Officer
Dirigeant
|
3 124
-100.0%
74,56
232 925 USD
|
3 124
-100.0%
|
74,56
|
232 925 USD
|
|
|
2011-10-05 |
2011-10-03 |
V
Vente
|
Price P Schaefer
President & CEO
Administrateur exécutif
|
40 000
-5.0%
79,33
3 173 316 USD
|
40 000
-5.0%
|
79,33
|
3 173 316 USD
|
|
|
2011-09-06 |
2011-09-01 |
V
Vente
|
Price P Schaefer
President and CEO
Administrateur exécutif
|
40 000
-5.0%
65,63
2 625 032 USD
|
40 000
-5.0%
|
65,63
|
2 625 032 USD
|
|
|
2011-09-06 |
2011-09-01 |
V
Vente
|
Berrey M Michelle
Chief Medical Officer
Dirigeant
|
3 124
-100.0%
65,63
205 015 USD
|
3 124
-100.0%
|
65,63
|
205 015 USD
|
|
|
2011-08-03 |
2011-08-01 |
V
Vente
|
Price P Schaefer
President and CEO
Administrateur exécutif
|
20 000
-5.0%
120,15
2 403 006 USD
|
20 000
-5.0%
|
120,15
|
2 403 006 USD
|
|
|
2011-08-03 |
2011-08-01 |
V
Vente
|
OTTO MICHAEL J.
Chief Scientific Officer
Dirigeant
|
8 929
-55.4%
119,99
1 071 391 USD
|
8 929
-55.4%
|
119,99
|
1 071 391 USD
|
|
|
2011-08-03 |
2011-08-01 |
V
Vente
|
Berrey M Michelle
Chief Medical Officer
Dirigeant
|
937
-100.0%
119,99
112 431 USD
|
937
-100.0%
|
119,99
|
112 431 USD
|
|
|
2011-07-05 |
2011-07-01 |
V
Vente
|
Price P Schaefer
President and CEO
Administrateur exécutif
|
20 000
-5.0%
110,47
2 209 326 USD
|
20 000
-5.0%
|
110,47
|
2 209 326 USD
|
|
|
2011-07-05 |
2011-07-01 |
V
Vente
|
Berrey M Michelle
Chief Medical Officer
Dirigeant
|
938
-100.0%
111,83
104 897 USD
|
938
-100.0%
|
111,83
|
104 897 USD
|
|
|
2011-06-03 |
2011-06-01 |
V
Vente
|
Price P Schaefer
President and CEO
Administrateur exécutif
|
20 000
-5.0%
100,54
2 010 706 USD
|
20 000
-5.0%
|
100,54
|
2 010 706 USD
|
|
|
2011-05-11 |
2011-05-09 |
V
Vente
|
Rogers Michael D.
Chief Development Officer
Dirigeant
|
10 000
-100.0%
109,08
1 090 800 USD
|
10 000
-100.0%
|
109,08
|
1 090 800 USD
|
|
|
2011-05-10 |
2011-05-06 |
V
Vente
|
Williamson Robert F III
Administrateur non-exécutif
|
31 666
-91.3%
104,36
3 304 607 USD
|
31 666
-91.3%
|
104,36
|
3 304 607 USD
|
|
|
2011-05-10 |
2011-05-06 |
V
Vente
|
LEUTZINGER KURT
Chief Financial Officer
Dirigeant
|
11 287
-5.7%
102,88
1 161 207 USD
|
11 287
-5.7%
|
102,88
|
1 161 207 USD
|
|
|
2011-05-09 |
2011-05-05 |
V
Vente
|
LEUTZINGER KURT
Chief Financial Officer
Dirigeant
|
9 546
-4.6%
102,61
979 515 USD
|
9 546
-4.6%
|
102,61
|
979 515 USD
|
|
|
2011-05-05 |
2011-05-03 |
V
Vente
|
CONRAD HERBERT J
Administrateur non-exécutif
|
40 000
-83.3%
99,04
3 961 584 USD
|
40 000
-83.3%
|
99,04
|
3 961 584 USD
|
|
|
2011-04-29 |
2011-04-28 |
V
Vente
|
OTTO MICHAEL J.
Chief Scientific Officer
Dirigeant
|
9 500
-56.9%
99,85
948 575 USD
|
9 500
-56.9%
|
99,85
|
948 575 USD
|
|
|
2011-04-29 |
2011-04-27 |
V
Vente
|
Rogers Michael D.
Chief Development Officer
Dirigeant
|
20 000
-100.0%
99,00
1 980 068 USD
|
20 000
-100.0%
|
99,00
|
1 980 068 USD
|
|
|
2011-04-29 |
2011-04-27 |
V
Vente
|
Berrey M Michelle
Chief Medical Officer
Dirigeant
|
9 375
-100.0%
100,60
943 125 USD
|
9 375
-100.0%
|
100,60
|
943 125 USD
|
|
|
2011-04-29 |
2011-04-27 |
V
Vente
|
Berrey M Michelle
Chief Medical Officer
Dirigeant
|
8 437
-100.0%
100,60
848 762 USD
|
8 437
-100.0%
|
100,60
|
848 762 USD
|
|
|
2011-04-29 |
2011-04-27 |
V
Vente
|
Berrey M Michelle
Chief Medical Officer
Dirigeant
|
21 875
-100.0%
100,60
2 200 625 USD
|
21 875
-100.0%
|
100,60
|
2 200 625 USD
|
|
|
2011-04-29 |
2011-04-27 |
V
Vente
|
Berrey M Michelle
Chief Medical Officer
Dirigeant
|
10 416
-100.0%
100,60
1 047 850 USD
|
10 416
-100.0%
|
100,60
|
1 047 850 USD
|
|
|
2011-03-24 |
2011-03-22 |
V
Vente
|
OTTO MICHAEL J.
Chief Scientific Officer
Dirigeant
|
6 279
-27.3%
64,00
401 856 USD
|
6 279
-27.3%
|
64,00
|
401 856 USD
|
|
|
2010-10-01 |
2010-10-01 |
V
Vente
|
OTTO MICHAEL J.
Chief Scientific Officer
Dirigeant
|
5 000
-23.1%
29,50
147 500 USD
|
5 000
-23.1%
|
29,50
|
147 500 USD
|
|
|
2010-09-29 |
2010-09-28 |
V
Vente
|
OTTO MICHAEL J.
Chief Scientific Officer
Dirigeant
|
12 811
-37.1%
29,50
377 925 USD
|
12 811
-37.1%
|
29,50
|
377 925 USD
|
|
|
2010-06-18 |
2010-06-17 |
V
Vente
|
Berrey M Michelle
Chief Medical Officer
Dirigeant
|
2 976
-100.0%
32,53
96 807 USD
|
2 976
-100.0%
|
32,53
|
96 807 USD
|
|
|
2009-09-24 |
2009-09-24 |
V
Vente
|
QVT Associates GP LLC
Actionnaire important
|
400 000
-12.5%
20,88
8 352 000 USD
|
400 000
-12.5%
|
20,88
|
8 352 000 USD
|
|
|
2009-09-24 |
2009-09-24 |
V
Vente
|
QVT Associates GP LLC
Actionnaire important
|
400 000
-11.1%
20,88
8 352 000 USD
|
400 000
-11.1%
|
20,88
|
8 352 000 USD
|
|
|
2009-09-24 |
2009-09-23 |
V
Vente
|
QVT Associates GP LLC
Actionnaire important
|
10 000
-0.3%
22,41
224 100 USD
|
10 000
-0.3%
|
22,41
|
224 100 USD
|
|
|
2009-09-24 |
2009-09-22 |
V
Vente
|
QVT Associates GP LLC
Actionnaire important
|
100 000
-2.7%
22,95
2 295 000 USD
|
100 000
-2.7%
|
22,95
|
2 295 000 USD
|
|
|
2009-09-21 |
2009-09-18 |
V
Vente
|
OTTO MICHAEL
Exec.VP,Pharm.Research
Dirigeant
|
4 600
-19.1%
21,97
101 062 USD
|
4 600
-19.1%
|
21,97
|
101 062 USD
|
|
|
2009-09-21 |
2009-09-18 |
V
Vente
|
OTTO MICHAEL
Exec.VP,Pharm.Research
Dirigeant
|
4 500
-65.1%
21,95
98 775 USD
|
4 500
-65.1%
|
21,95
|
98 775 USD
|
|
|
2009-09-21 |
2009-09-18 |
V
Vente
|
OTTO MICHAEL
Exec.VP,Pharm.Research
Dirigeant
|
8 200
-22.3%
21,94
179 908 USD
|
8 200
-22.3%
|
21,94
|
179 908 USD
|
|
|
2009-09-21 |
2009-09-18 |
V
Vente
|
OTTO MICHAEL
Exec.VP,Pharm.Research
Dirigeant
|
9 300
-20.2%
21,92
203 856 USD
|
9 300
-20.2%
|
21,92
|
203 856 USD
|
|
|
2009-09-21 |
2009-09-18 |
V
Vente
|
OTTO MICHAEL
Exec.VP,Pharm.Research
Dirigeant
|
13 400
-22.5%
21,90
293 460 USD
|
13 400
-22.5%
|
21,90
|
293 460 USD
|
|
|
2009-03-02 |
2009-02-27 |
A
Achat
|
INOUYE MICHAEL K
Administrateur non-exécutif
|
200
+4.7%
10,11
2 022 USD
|
200
+4.7%
|
10,11
|
2 022 USD
|
|
|
2009-03-02 |
2009-02-27 |
A
Achat
|
INOUYE MICHAEL K
Administrateur non-exécutif
|
192
+4.7%
10,10
1 939 USD
|
192
+4.7%
|
10,10
|
1 939 USD
|
|
|
2009-03-02 |
2009-02-27 |
A
Achat
|
INOUYE MICHAEL K
Administrateur non-exécutif
|
300
+7.9%
10,09
3 027 USD
|
300
+7.9%
|
10,09
|
3 027 USD
|
|
|
2009-03-02 |
2009-02-27 |
A
Achat
|
INOUYE MICHAEL K
Administrateur non-exécutif
|
58
+1.5%
10,07
584 USD
|
58
+1.5%
|
10,07
|
584 USD
|
|
|
2009-03-02 |
2009-02-27 |
A
Achat
|
INOUYE MICHAEL K
Administrateur non-exécutif
|
500
+15.4%
10,11
5 053 USD
|
500
+15.4%
|
10,11
|
5 053 USD
|
|
|
2009-03-02 |
2009-02-26 |
A
Achat
|
INOUYE MICHAEL K
Administrateur non-exécutif
|
119
+3.8%
10,68
1 271 USD
|
119
+3.8%
|
10,68
|
1 271 USD
|
|
|
2009-03-02 |
2009-02-26 |
A
Achat
|
INOUYE MICHAEL K
Administrateur non-exécutif
|
100
+3.3%
10,67
1 067 USD
|
100
+3.3%
|
10,67
|
1 067 USD
|
|
|
2009-03-02 |
2009-02-26 |
A
Achat
|
INOUYE MICHAEL K
Administrateur non-exécutif
|
200
+7.1%
10,64
2 128 USD
|
200
+7.1%
|
10,64
|
2 128 USD
|
|
|
2009-03-02 |
2009-02-26 |
A
Achat
|
INOUYE MICHAEL K
Administrateur non-exécutif
|
300
+11.9%
10,65
3 195 USD
|
300
+11.9%
|
10,65
|
3 195 USD
|
|
|
2009-03-02 |
2009-02-26 |
A
Achat
|
INOUYE MICHAEL K
Administrateur non-exécutif
|
300
+13.4%
10,63
3 189 USD
|
300
+13.4%
|
10,63
|
3 189 USD
|
|
|
2009-03-02 |
2009-02-26 |
A
Achat
|
INOUYE MICHAEL K
Administrateur non-exécutif
|
131
+6.2%
10,60
1 389 USD
|
131
+6.2%
|
10,60
|
1 389 USD
|
|
|
2009-03-02 |
2009-02-26 |
A
Achat
|
INOUYE MICHAEL K
Administrateur non-exécutif
|
100
+5.0%
10,59
1 059 USD
|
100
+5.0%
|
10,59
|
1 059 USD
|
|
|
2009-02-26 |
2009-02-25 |
A
Achat
|
LUBETKIN PAUL
Executive VP & General Counsel
Dirigeant
|
125
+33.3%
10,14
1 268 USD
|
125
+33.3%
|
10,14
|
1 268 USD
|
|
|
2009-02-26 |
2009-02-25 |
A
Achat
|
LUBETKIN PAUL
Executive VP & General Counsel
Dirigeant
|
175
+87.5%
10,65
1 864 USD
|
175
+87.5%
|
10,65
|
1 864 USD
|
|
|
2009-02-26 |
2009-02-25 |
A
Achat
|
LUBETKIN PAUL
Executive VP & General Counsel
Dirigeant
|
200
+inf%
10,64
2 128 USD
|
200
+inf%
|
10,64
|
2 128 USD
|
|
|
2008-11-17 |
2008-11-13 |
V
Vente
|
Rogers Michael D.
Chief Development Officer
Dirigeant
|
600
-100.0%
18,75
11 250 USD
|
600
-100.0%
|
18,75
|
11 250 USD
|
|
|
2008-11-17 |
2008-11-13 |
V
Vente
|
Rogers Michael D.
Chief Development Officer
Dirigeant
|
1
-0.2%
18,72
19 USD
|
1
-0.2%
|
18,72
|
19 USD
|
|
|
2008-11-17 |
2008-11-13 |
V
Vente
|
Rogers Michael D.
Chief Development Officer
Dirigeant
|
300
-33.3%
18,71
5 613 USD
|
300
-33.3%
|
18,71
|
5 613 USD
|
|
|
2008-11-17 |
2008-11-13 |
V
Vente
|
Rogers Michael D.
Chief Development Officer
Dirigeant
|
300
-25.0%
18,70
5 610 USD
|
300
-25.0%
|
18,70
|
5 610 USD
|
|
|
2008-11-17 |
2008-11-13 |
V
Vente
|
Rogers Michael D.
Chief Development Officer
Dirigeant
|
499
-29.4%
18,69
9 326 USD
|
499
-29.4%
|
18,69
|
9 326 USD
|
|
|
2008-11-17 |
2008-11-13 |
V
Vente
|
Rogers Michael D.
Chief Development Officer
Dirigeant
|
701
-29.2%
18,65
13 074 USD
|
701
-29.2%
|
18,65
|
13 074 USD
|
|
|
2008-11-17 |
2008-11-13 |
V
Vente
|
Rogers Michael D.
Chief Development Officer
Dirigeant
|
100
-4.0%
18,63
1 863 USD
|
100
-4.0%
|
18,63
|
1 863 USD
|
|
|
2008-11-17 |
2008-11-13 |
V
Vente
|
Rogers Michael D.
Chief Development Officer
Dirigeant
|
100
-3.3%
18,59
1 859 USD
|
100
-3.3%
|
18,59
|
1 859 USD
|
|
|
2008-11-17 |
2008-11-13 |
V
Vente
|
Rogers Michael D.
Chief Development Officer
Dirigeant
|
200
-6.2%
18,58
3 716 USD
|
200
-6.2%
|
18,58
|
3 716 USD
|
|
|
2008-11-17 |
2008-11-13 |
V
Vente
|
Rogers Michael D.
Chief Development Officer
Dirigeant
|
99
-3.0%
18,55
1 836 USD
|
99
-3.0%
|
18,55
|
1 836 USD
|
|
|
2008-11-17 |
2008-11-13 |
V
Vente
|
Rogers Michael D.
Chief Development Officer
Dirigeant
|
600
-15.4%
18,50
11 100 USD
|
600
-15.4%
|
18,50
|
11 100 USD
|
|
|
2008-11-17 |
2008-11-13 |
V
Vente
|
Rogers Michael D.
Chief Development Officer
Dirigeant
|
300
-7.1%
18,43
5 529 USD
|
300
-7.1%
|
18,43
|
5 529 USD
|
|
|
2008-11-17 |
2008-11-13 |
V
Vente
|
Rogers Michael D.
Chief Development Officer
Dirigeant
|
300
-6.7%
18,40
5 520 USD
|
300
-6.7%
|
18,40
|
5 520 USD
|
|
|
2008-11-17 |
2008-11-13 |
V
Vente
|
Rogers Michael D.
Chief Development Officer
Dirigeant
|
70
-1.5%
18,39
1 287 USD
|
70
-1.5%
|
18,39
|
1 287 USD
|
|
|
2008-11-17 |
2008-11-13 |
V
Vente
|
Rogers Michael D.
Chief Development Officer
Dirigeant
|
100
-2.1%
18,38
1 838 USD
|
100
-2.1%
|
18,38
|
1 838 USD
|
|
|
2008-11-17 |
2008-11-13 |
V
Vente
|
Rogers Michael D.
Chief Development Officer
Dirigeant
|
100
-2.1%
18,37
1 837 USD
|
100
-2.1%
|
18,37
|
1 837 USD
|
|
|
2008-11-17 |
2008-11-13 |
V
Vente
|
Rogers Michael D.
Chief Development Officer
Dirigeant
|
1 430
-23.1%
18,35
26 241 USD
|
1 430
-23.1%
|
18,35
|
26 241 USD
|
|
|
2008-11-17 |
2008-11-13 |
V
Vente
|
Rogers Michael D.
Chief Development Officer
Dirigeant
|
400
-6.1%
18,32
7 328 USD
|
400
-6.1%
|
18,32
|
7 328 USD
|
|
|
2008-11-17 |
2008-11-13 |
V
Vente
|
Rogers Michael D.
Chief Development Officer
Dirigeant
|
300
-4.3%
18,29
5 487 USD
|
300
-4.3%
|
18,29
|
5 487 USD
|
|
|
2008-11-17 |
2008-11-13 |
V
Vente
|
Rogers Michael D.
Chief Development Officer
Dirigeant
|
400
-5.5%
18,27
7 308 USD
|
400
-5.5%
|
18,27
|
7 308 USD
|
|
|
2008-11-17 |
2008-11-13 |
V
Vente
|
Rogers Michael D.
Chief Development Officer
Dirigeant
|
400
-5.2%
18,26
7 304 USD
|
400
-5.2%
|
18,26
|
7 304 USD
|
|
|
2008-11-17 |
2008-11-13 |
V
Vente
|
Rogers Michael D.
Chief Development Officer
Dirigeant
|
1 672
-17.8%
18,25
30 514 USD
|
1 672
-17.8%
|
18,25
|
30 514 USD
|
|
|
2008-11-17 |
2008-11-13 |
V
Vente
|
Rogers Michael D.
Chief Development Officer
Dirigeant
|
600
-6.0%
18,24
10 944 USD
|
600
-6.0%
|
18,24
|
10 944 USD
|
|
