|
2025-01-17 |
2025-01-15 |
V
Vente
|
Hager Alicia J.
Chief Legal Officer
Dirigeant
|
9 584
-6.1%
2,20
21 085 USD
|
9 584
-6.1%
|
2,20
|
21 085 USD
|
|
|
2025-01-17 |
2025-01-15 |
V
Vente
|
Brandenberger Ralph
Chief Technical Officer
Dirigeant
|
7 447
-5.6%
2,20
16 383 USD
|
7 447
-5.6%
|
2,20
|
16 383 USD
|
|
|
2025-01-17 |
2025-01-15 |
V
Vente
|
HASTINGS PAUL J
Chief Executive Officer
Administrateur exécutif
|
17 378
-5.2%
2,20
38 232 USD
|
17 378
-5.2%
|
2,20
|
38 232 USD
|
|
|
2025-01-17 |
2025-01-15 |
V
Vente
|
Shook David
See Remarks
Dirigeant
|
8 638
-4.3%
2,20
19 004 USD
|
8 638
-4.3%
|
2,20
|
19 004 USD
|
|
|
2025-01-17 |
2025-01-15 |
V
Vente
|
Levin Alyssa
See Remarks
Dirigeant
|
5 838
-5.4%
2,20
12 844 USD
|
5 838
-5.4%
|
2,20
|
12 844 USD
|
|
|
2024-07-18 |
2024-07-16 |
VP
Vente planifiée
|
Hager Alicia J.
Chief Legal Officer
Dirigeant
|
3 396
-3.2%
8,00
27 168 USD
|
3 396
-3.2%
|
8,00
|
27 168 USD
|
|
|
2024-06-20 |
2024-06-18 |
V
Vente
|
Shook David
Chief Medical Officer
Dirigeant
|
456
-0.4%
5,60
2 554 USD
|
456
-0.4%
|
5,60
|
2 554 USD
|
|
|
2024-06-20 |
2024-06-18 |
V
Vente
|
Trager James
Chief Scientific Officer
Dirigeant
|
456
-0.3%
5,60
2 554 USD
|
456
-0.3%
|
5,60
|
2 554 USD
|
|
|
2024-06-20 |
2024-06-18 |
V
Vente
|
Hager Alicia J.
Chief Legal Officer
Dirigeant
|
727
-0.7%
5,60
4 071 USD
|
727
-0.7%
|
5,60
|
4 071 USD
|
|
|
2024-06-20 |
2024-06-18 |
V
Vente
|
HASTINGS PAUL J
Chief Executive Officer
Administrateur exécutif
|
1 770
-0.7%
5,60
9 912 USD
|
1 770
-0.7%
|
5,60
|
9 912 USD
|
|
|
2024-06-20 |
2024-06-18 |
V
Vente
|
Brandenberger Ralph
Chief Technical Officer
Dirigeant
|
229
-0.3%
5,60
1 282 USD
|
229
-0.3%
|
5,60
|
1 282 USD
|
|
|
2024-03-29 |
2024-03-27 |
A
Achat
|
RA CAPITAL MANAGEMENT, L.P.
Administrateur non-exécutif
Actionnaire important
|
3 000 000
+42.5%
10,00
30 000 000 USD
|
3 000 000
+42.5%
|
10,00
|
30 000 000 USD
|
|
|
2024-03-28 |
2024-03-27 |
A
Achat
|
George Simeon
Administrateur non-exécutif
|
451 659
+inf%
10,00
4 516 590 USD
|
451 659
+inf%
|
10,00
|
4 516 590 USD
|
|
|
2024-03-28 |
2024-03-27 |
A
Achat
|
George Simeon
Administrateur non-exécutif
|
1 548 341
+inf%
10,00
15 483 410 USD
|
1 548 341
+inf%
|
10,00
|
15 483 410 USD
|
|
|
2024-03-05 |
2024-03-01 |
VP
Vente planifiée
|
Brandenberger Ralph
Chief Technical Officer
Dirigeant
|
8 367
-9.5%
12,51
104 671 USD
|
8 367
-9.5%
|
12,51
|
104 671 USD
|
|
|
2024-02-14 |
2024-02-12 |
VP
Vente planifiée
|
Trager James
Chief Scientific Officer
Dirigeant
|
4 143
-2.7%
12,00
49 716 USD
|
4 143
-2.7%
|
12,00
|
49 716 USD
|
|
|
2024-01-18 |
2024-01-16 |
V
Vente
|
Brandenberger Ralph
Chief Technical Officer
Dirigeant
|
2 512
-3.0%
8,74
21 955 USD
|
2 512
-3.0%
|
8,74
|
21 955 USD
|
|
|
2024-01-18 |
2024-01-16 |
V
Vente
|
Shook David
Chief Medical Officer
Dirigeant
|
3 552
-3.0%
8,74
31 044 USD
|
3 552
-3.0%
|
8,74
|
31 044 USD
|
|
|
2024-01-18 |
2024-01-16 |
V
Vente
|
Trager James
Chief Scientific Officer
Dirigeant
|
4 560
-2.9%
8,74
39 854 USD
|
4 560
-2.9%
|
8,74
|
39 854 USD
|
|
|
2024-01-18 |
2024-01-16 |
V
Vente
|
Hager Alicia J.
Chief Legal Officer
Dirigeant
|
4 554
-4.0%
8,74
39 802 USD
|
4 554
-4.0%
|
8,74
|
39 802 USD
|
|
|
2024-01-18 |
2024-01-16 |
V
Vente
|
HASTINGS PAUL J
Chief Executive Officer
Administrateur exécutif
|
9 697
-2.4%
8,74
84 752 USD
|
9 697
-2.4%
|
8,74
|
84 752 USD
|
|
|
2023-08-23 |
2023-08-21 |
V
Vente
|
Shook David
Chief Medical Officer
Dirigeant
|
1 331
-2.2%
1,83
2 436 USD
|
1 331
-2.2%
|
1,83
|
2 436 USD
|
|
|
2023-06-22 |
2023-06-20 |
VP
Vente planifiée
|
Mahmood Nadir
See Remarks
Dirigeant
|
526
-0.6%
4,85
2 551 USD
|
526
-0.6%
|
4,85
|
2 551 USD
|
|
|
2023-06-22 |
2023-06-20 |
VP
Vente planifiée
|
Trager James
Chief Scientific Officer
Dirigeant
|
439
-0.4%
4,85
2 129 USD
|
439
-0.4%
|
4,85
|
2 129 USD
|
|
|
2023-06-22 |
2023-06-20 |
V
Vente
|
Brandenberger Ralph
Chief Technical Officer
Dirigeant
|
221
-0.8%
4,85
1 072 USD
|
221
-0.8%
|
4,85
|
1 072 USD
|
|
|
2023-06-22 |
2023-06-20 |
VP
Vente planifiée
|
HASTINGS PAUL J
Chief Executive Officer
Administrateur exécutif
|
1 704
-0.5%
4,85
8 264 USD
|
1 704
-0.5%
|
4,85
|
8 264 USD
|
|
|
2023-06-22 |
2023-06-20 |
V
Vente
|
Hager Alicia J.
Chief Legal Officer
Dirigeant
|
701
-1.2%
4,85
3 400 USD
|
701
-1.2%
|
4,85
|
3 400 USD
|
|
|
2023-06-22 |
2023-06-20 |
VP
Vente planifiée
|
Shook David
Chief Medical Officer
Dirigeant
|
439
-0.7%
4,85
2 129 USD
|
439
-0.7%
|
4,85
|
2 129 USD
|
|
|
2023-01-18 |
2023-01-17 |
V
Vente
|
Hager Alicia J.
Chief Legal Officer
Dirigeant
|
1 103
-1.9%
5,49
6 055 USD
|
1 103
-1.9%
|
5,49
|
6 055 USD
|
|
|
2023-01-18 |
2023-01-17 |
VP
Vente planifiée
|
HASTINGS PAUL J
Chief Executive Officer
Administrateur exécutif
|
3 691
-1.2%
5,49
20 264 USD
|
3 691
-1.2%
|
5,49
|
20 264 USD
|
|
|
2023-01-18 |
2023-01-17 |
V
Vente
|
Trager James
Chief Scientific Officer
Dirigeant
|
1 115
-1.1%
5,49
6 121 USD
|
1 115
-1.1%
|
5,49
|
6 121 USD
|
|
|
2023-01-18 |
2023-01-17 |
V
Vente
|
Brandenberger Ralph
Chief Technical Officer
Dirigeant
|
491
-1.7%
5,49
2 696 USD
|
491
-1.7%
|
5,49
|
2 696 USD
|
|
|
2023-01-18 |
2023-01-17 |
V
Vente
|
Shook David
Chief Medical Officer
Dirigeant
|
175
-0.3%
5,49
961 USD
|
175
-0.3%
|
5,49
|
961 USD
|
|
|
2023-01-18 |
2023-01-17 |
VP
Vente planifiée
|
Mahmood Nadir
See Remarks
Dirigeant
|
1 122
-1.3%
5,49
6 160 USD
|
1 122
-1.3%
|
5,49
|
6 160 USD
|
|
|
2022-10-07 |
2022-10-06 |
VP
Vente planifiée
|
Brandenberger Ralph
Chief Technical Officer
Dirigeant
|
842
-9.7%
14,02
11 805 USD
|
842
-9.7%
|
14,02
|
11 805 USD
|
|
|
2022-09-22 |
2022-09-21 |
VP
Vente planifiée
|
HASTINGS PAUL J
Chief Executive Officer
Administrateur exécutif
|
6 126
-2.2%
13,01
79 717 USD
|
6 126
-2.2%
|
13,01
|
79 717 USD
|
|
|
2022-08-17 |
2022-08-15 |
VP
Vente planifiée
|
Trager James
Chief Scientific Officer
Dirigeant
|
5 000
-7.4%
17,53
87 656 USD
|
5 000
-7.4%
|
17,53
|
87 656 USD
|
|
|
2022-08-17 |
2022-08-15 |
VP
Vente planifiée
|
Brandenberger Ralph
Chief Technical Officer
Dirigeant
|
11 000
-58.5%
17,64
194 052 USD
|
11 000
-58.5%
|
17,64
|
194 052 USD
|
|
|
2022-08-17 |
2022-08-15 |
VP
Vente planifiée
|
Mahmood Nadir
See Remarks
Dirigeant
|
7 500
-14.0%
18,03
135 215 USD
|
7 500
-14.0%
|
18,03
|
135 215 USD
|
|
|
2022-08-10 |
2022-08-08 |
VP
Vente planifiée
|
Mahmood Nadir
See Remarks
Dirigeant
|
7 500
-14.0%
15,32
114 900 USD
|
7 500
-14.0%
|
15,32
|
114 900 USD
|
|
|
2022-08-10 |
2022-08-08 |
VP
Vente planifiée
|
Brandenberger Ralph
Chief Technical Officer
Dirigeant
|
11 593
-59.8%
15,51
179 783 USD
|
11 593
-59.8%
|
15,51
|
179 783 USD
|
|
|
2022-07-26 |
2022-07-25 |
VP
Vente planifiée
|
Mahmood Nadir
See Remarks
Dirigeant
|
7 500
-14.0%
13,40
100 480 USD
|
7 500
-14.0%
|
13,40
|
100 480 USD
|
|
|
2022-07-26 |
2022-07-25 |
VP
Vente planifiée
|
Brandenberger Ralph
Chief Technical Officer
Dirigeant
|
3 000
-27.8%
13,41
40 230 USD
|
3 000
-27.8%
|
13,41
|
40 230 USD
|
|
|
2022-06-07 |
2022-06-03 |
VP
Vente planifiée
|
Brandenberger Ralph
Sr. VP, Technical Operations
Dirigeant
|
4 140
-43.9%
15,00
62 100 USD
|
4 140
-43.9%
|
15,00
|
62 100 USD
|
|
|
2022-04-29 |
2022-04-28 |
A
Achat
|
George Simeon
Administrateur non-exécutif
|
666 666
+inf%
15,00
9 999 990 USD
|
666 666
+inf%
|
15,00
|
9 999 990 USD
|
|
|
2022-04-29 |
2022-04-28 |
A
Achat
|
George Simeon
Administrateur non-exécutif
|
666 667
+inf%
15,00
10 000 005 USD
|
666 667
+inf%
|
15,00
|
10 000 005 USD
|
|
|
2022-04-28 |
2022-04-26 |
A
Achat
|
RA CAPITAL MANAGEMENT, L.P.
Administrateur non-exécutif
Actionnaire important
|
2 200 000
+39.2%
15,00
33 000 000 USD
|
2 200 000
+39.2%
|
15,00
|
33 000 000 USD
|
|
|
2021-12-03 |
2021-12-01 |
VP
Vente planifiée
|
Brandenberger Ralph
Sr. VP, Technical Operations
Dirigeant
|
4 140
-100.0%
15,64
64 750 USD
|
4 140
-100.0%
|
15,64
|
64 750 USD
|
|
|
2021-10-01 |
2021-09-29 |
VP
Vente planifiée
|
HASTINGS PAUL J
Chief Executive Officer
Administrateur exécutif
|
223
-0.1%
26,53
5 916 USD
|
223
-0.1%
|
26,53
|
5 916 USD
|
|
|
2021-10-01 |
2021-09-29 |
VP
Vente planifiée
|
HASTINGS PAUL J
Chief Executive Officer
Administrateur exécutif
|
8 277
-3.6%
27,20
225 134 USD
|
8 277
-3.6%
|
27,20
|
225 134 USD
|
|
|
2021-09-02 |
2021-09-01 |
VP
Vente planifiée
|
Brandenberger Ralph
See Remarks
Dirigeant
|
4 140
-100.0%
32,08
132 811 USD
|
4 140
-100.0%
|
32,08
|
132 811 USD
|
|
|
2021-08-09 |
2021-08-05 |
VP
Vente planifiée
|
Rajangam Kanya
Chief Medical Officer
Dirigeant
|
10 000
-100.0%
37,28
372 800 USD
|
10 000
-100.0%
|
37,28
|
372 800 USD
|
|
|
2021-07-06 |
2021-07-01 |
VP
Vente planifiée
|
Mahmood Nadir
See Remarks
Dirigeant
|
6 500
-19.2%
31,71
206 115 USD
|
6 500
-19.2%
|
31,71
|
206 115 USD
|
|
|
2021-06-23 |
2021-06-21 |
VP
Vente planifiée
|
HASTINGS PAUL J
Chief Executive Officer
Administrateur exécutif
|
3 807
-1.6%
26,89
102 370 USD
|
3 807
-1.6%
|
26,89
|
102 370 USD
|
|
|
2021-06-23 |
2021-06-21 |
VP
Vente planifiée
|
HASTINGS PAUL J
Chief Executive Officer
Administrateur exécutif
|
4 693
-2.0%
26,39
123 848 USD
|
4 693
-2.0%
|
26,39
|
123 848 USD
|
|
|
2021-06-04 |
2021-06-02 |
VP
Vente planifiée
|
Brandenberger Ralph
See Remarks
Dirigeant
|
4 140
-100.0%
24,50
101 430 USD
|
4 140
-100.0%
|
24,50
|
101 430 USD
|
|
|
2021-05-12 |
2021-05-10 |
VP
Vente planifiée
|
Mahmood Nadir
See Remarks
Dirigeant
|
3 000
-9.5%
27,16
81 480 USD
|
3 000
-9.5%
|
27,16
|
81 480 USD
|
|
|
2021-05-05 |
2021-05-03 |
VP
Vente planifiée
|
Trager James
Chief Scientific Officer
Dirigeant
|
2 250
-4.7%
31,64
71 190 USD
|
2 250
-4.7%
|
31,64
|
71 190 USD
|
|
|
2021-05-05 |
2021-05-03 |
VP
Vente planifiée
|
Trager James
Chief Scientific Officer
Dirigeant
|
1 350
-2.9%
31,64
42 714 USD
|
1 350
-2.9%
|
31,64
|
42 714 USD
|
|
|
2021-04-02 |
2021-04-01 |
VP
Vente planifiée
|
Mahmood Nadir
See Remarks
Dirigeant
|
3 500
-10.0%
32,70
114 450 USD
|
3 500
-10.0%
|
32,70
|
114 450 USD
|
|
|
2021-04-01 |
2021-03-30 |
VP
Vente planifiée
|
HASTINGS PAUL J
Chief Executive Officer
Administrateur exécutif
|
3 130
-1.3%
32,21
100 817 USD
|
3 130
-1.3%
|
32,21
|
100 817 USD
|
|
|
2021-04-01 |
2021-03-30 |
VP
Vente planifiée
|
HASTINGS PAUL J
Chief Executive Officer
Administrateur exécutif
|
2 409
-1.0%
31,24
75 257 USD
|
2 409
-1.0%
|
31,24
|
75 257 USD
|
|
|
2021-04-01 |
2021-03-30 |
VP
Vente planifiée
|
HASTINGS PAUL J
Chief Executive Officer
Administrateur exécutif
|
11 461
-4.5%
30,23
346 466 USD
|
11 461
-4.5%
|
30,23
|
346 466 USD
|
|
|
2021-02-03 |
2021-02-02 |
VP
Vente planifiée
|
Trager James
Chief Scientific Officer
Dirigeant
|
2 800
-5.6%
40,00
112 000 USD
|
2 800
-5.6%
|
40,00
|
112 000 USD
|
|
|
2021-02-03 |
2021-02-01 |
VP
Vente planifiée
|
Trager James
Chief Scientific Officer
Dirigeant
|
1 566
-3.2%
39,46
61 794 USD
|
1 566
-3.2%
|
39,46
|
61 794 USD
|
|
|
2021-02-03 |
2021-02-01 |
VP
Vente planifiée
|
Trager James
Chief Scientific Officer
Dirigeant
|
2 034
-4.0%
38,07
77 434 USD
|
2 034
-4.0%
|
38,07
|
77 434 USD
|
|
|
2021-01-26 |
2021-01-25 |
VP
Vente planifiée
|
Mahmood Nadir
See Remarks
Dirigeant
|
3 500
-10.0%
48,40
169 400 USD
|
3 500
-10.0%
|
48,40
|
169 400 USD
|
|
|
2021-01-26 |
2021-01-25 |
VP
Vente planifiée
|
Mahmood Nadir
See Remarks
Dirigeant
|
2 000
-5.4%
48,86
97 720 USD
|
2 000
-5.4%
|
48,86
|
97 720 USD
|
|
|
2020-07-16 |
2020-07-14 |
A
Achat
|
Makhzoumi Mohamad
Actionnaire important
|
666 666
+29.8%
18,00
11 999 988 USD
|
666 666
+29.8%
|
18,00
|
11 999 988 USD
|
|
|
2020-07-16 |
2020-07-14 |
A
Achat
|
GLAXOSMITHKLINE PLC
Administrateur non-exécutif
Actionnaire important
|
833 333
+36.0%
18,00
14 999 994 USD
|
833 333
+36.0%
|
18,00
|
14 999 994 USD
|
|
|
2020-07-16 |
2020-07-14 |
A
Achat
|
RA CAPITAL MANAGEMENT, L.P.
Actionnaire important
|
3 333 333
+146.7%
18,00
59 999 994 USD
|
3 333 333
+146.7%
|
18,00
|
59 999 994 USD
|
|
|
2020-07-16 |
2020-07-14 |
A
Achat
|
SANDELL SCOTT D
Actionnaire important
|
666 666
+29.8%
18,00
11 999 988 USD
|
666 666
+29.8%
|
18,00
|
11 999 988 USD
|
|
|
2020-07-16 |
2020-07-14 |
A
Achat
|
MAKOWER JOSHUA
Actionnaire important
|
666 666
+29.8%
18,00
11 999 988 USD
|
666 666
+29.8%
|
18,00
|
11 999 988 USD
|
|
|
2020-07-16 |
2020-07-14 |
A
Achat
|
Novo Holdings A/S
Actionnaire important
|
555 555
+24.8%
18,00
9 999 990 USD
|
555 555
+24.8%
|
18,00
|
9 999 990 USD
|
|
|
2020-07-16 |
2020-07-14 |
A
Achat
|
BASKETT FOREST
Actionnaire important
|
666 666
+29.8%
18,00
11 999 988 USD
|
666 666
+29.8%
|
18,00
|
11 999 988 USD
|
|
