|
2008-11-19 |
2008-11-19 |
A
Achat
|
Laikind Paul K
Chief Executive Officer
Dirigeant
|
100
+0.0%
0,53
53 USD
|
100
+0.0%
|
0,53
|
53 USD
|
|
|
2008-11-19 |
2008-11-19 |
A
Achat
|
Laikind Paul K
Chief Executive Officer
Dirigeant
|
100
+0.0%
0,49
49 USD
|
100
+0.0%
|
0,49
|
49 USD
|
|
|
2008-11-19 |
2008-11-19 |
A
Achat
|
Laikind Paul K
Chief Executive Officer
Dirigeant
|
837
+0.1%
0,57
477 USD
|
837
+0.1%
|
0,57
|
477 USD
|
|
|
2008-11-19 |
2008-11-19 |
A
Achat
|
Laikind Paul K
Chief Executive Officer
Dirigeant
|
100
+0.0%
0,55
55 USD
|
100
+0.0%
|
0,55
|
55 USD
|
|
|
2008-11-19 |
2008-11-19 |
A
Achat
|
Laikind Paul K
Chief Executive Officer
Dirigeant
|
963
+0.1%
0,75
722 USD
|
963
+0.1%
|
0,75
|
722 USD
|
|
|
2008-11-19 |
2008-11-19 |
A
Achat
|
Laikind Paul K
Chief Executive Officer
Dirigeant
|
200
+0.0%
0,74
148 USD
|
200
+0.0%
|
0,74
|
148 USD
|
|
|
2008-11-19 |
2008-11-19 |
A
Achat
|
Laikind Paul K
Chief Executive Officer
Dirigeant
|
800
+0.1%
0,70
560 USD
|
800
+0.1%
|
0,70
|
560 USD
|
|
|
2008-11-19 |
2008-11-19 |
A
Achat
|
Laikind Paul K
Chief Executive Officer
Dirigeant
|
500
+0.1%
0,69
345 USD
|
500
+0.1%
|
0,69
|
345 USD
|
|
|
2008-11-19 |
2008-11-19 |
A
Achat
|
Laikind Paul K
Chief Executive Officer
Dirigeant
|
500
+0.1%
0,68
340 USD
|
500
+0.1%
|
0,68
|
340 USD
|
|
|
2008-11-19 |
2008-11-19 |
A
Achat
|
Laikind Paul K
Chief Executive Officer
Dirigeant
|
100
+0.0%
0,67
67 USD
|
100
+0.0%
|
0,67
|
67 USD
|
|
|
2008-11-19 |
2008-11-19 |
A
Achat
|
Laikind Paul K
Chief Executive Officer
Dirigeant
|
400
+0.1%
0,63
252 USD
|
400
+0.1%
|
0,63
|
252 USD
|
|
|
2008-11-19 |
2008-11-19 |
A
Achat
|
Laikind Paul K
Chief Executive Officer
Dirigeant
|
100
+0.0%
0,56
56 USD
|
100
+0.0%
|
0,56
|
56 USD
|
|
|
2008-11-19 |
2008-11-18 |
A
Achat
|
Laikind Paul K
Chief Executive Officer
Dirigeant
|
300
+0.0%
0,59
177 USD
|
300
+0.0%
|
0,59
|
177 USD
|
|
|
2008-11-19 |
2008-11-18 |
A
Achat
|
Laikind Paul K
Chief Executive Officer
Dirigeant
|
500
+0.1%
0,56
280 USD
|
500
+0.1%
|
0,56
|
280 USD
|
|
|
2008-11-19 |
2008-11-18 |
A
Achat
|
Laikind Paul K
Chief Executive Officer
Dirigeant
|
100
+0.0%
0,51
51 USD
|
100
+0.0%
|
0,51
|
51 USD
|
|
|
2008-04-18 |
2008-04-16 |
A
Achat
|
ORONSKY ARNOLD L
Administrateur non-exécutif
Actionnaire important
|
45 239
+37.6%
2,34
105 859 USD
|
45 239
+37.6%
|
2,34
|
105 859 USD
|
|
|
2008-04-18 |
2008-04-16 |
A
Achat
|
INTERWEST PARTNERS VII L P
Actionnaire important
|
45 239
+37.6%
2,34
105 859 USD
|
45 239
+37.6%
|
2,34
|
105 859 USD
|
|
|
2008-04-18 |
2008-04-16 |
A
Achat
|
EVNIN LUKE
Administrateur non-exécutif
Actionnaire important
|
71 866
+1.5%
2,34
168 166 USD
|
71 866
+1.5%
|
2,34
|
168 166 USD
|
|
|
2008-04-18 |
2008-04-16 |
A
Achat
|
MPM BIOVENTURES II QP LP
Actionnaire important
|
71 866
+1.5%
2,34
168 166 USD
|
71 866
+1.5%
|
2,34
|
168 166 USD
|
|
|
2008-04-18 |
2008-04-16 |
A
Achat
|
ORONSKY ARNOLD L
Administrateur non-exécutif
Actionnaire important
|
945 577
+37.7%
2,34
2 212 650 USD
|
945 577
+37.7%
|
2,34
|
2 212 650 USD
|
|
|
2008-04-18 |
2008-04-16 |
A
Achat
|
CREDIT SUISSE/
Actionnaire important
|
196 633
+5.4%
2,34
460 121 USD
|
196 633
+5.4%
|
2,34
|
460 121 USD
|
|
|
2008-04-18 |
2008-04-16 |
A
Achat
|
INTERWEST PARTNERS VII L P
Actionnaire important
|
945 577
+37.7%
2,34
2 212 650 USD
|
945 577
+37.7%
|
2,34
|
2 212 650 USD
|
|
|
2008-04-17 |
2008-04-16 |
A
Achat
|
HALE DAVID F
Administrateur non-exécutif
|
10 000
+19.9%
2,34
23 400 USD
|
10 000
+19.9%
|
2,34
|
23 400 USD
|
|
|
2007-06-21 |
2007-06-19 |
VP
Vente planifiée
|
Beck John W
Chief Financial Officer
Dirigeant
|
2 611
-1.1%
8,08
21 097 USD
|
2 611
-1.1%
|
8,08
|
21 097 USD
|
|
|
2007-06-21 |
2007-06-19 |
VP
Vente planifiée
|
Beck John W
Chief Financial Officer
Dirigeant
|
100
-0.0%
8,06
806 USD
|
100
-0.0%
|
8,06
|
806 USD
|
|
|
2007-06-21 |
2007-06-19 |
VP
Vente planifiée
|
Beck John W
Chief Financial Officer
Dirigeant
|
100
-0.0%
8,03
803 USD
|
100
-0.0%
|
8,03
|
803 USD
|
|
|
2007-06-21 |
2007-06-19 |
VP
Vente planifiée
|
Beck John W
Chief Financial Officer
Dirigeant
|
100
-0.0%
8,04
804 USD
|
100
-0.0%
|
8,04
|
804 USD
|
|
|
2007-06-21 |
2007-06-19 |
VP
Vente planifiée
|
Beck John W
Chief Financial Officer
Dirigeant
|
489
-0.2%
8,05
3 936 USD
|
489
-0.2%
|
8,05
|
3 936 USD
|
|
|
2007-06-05 |
2007-06-01 |
VP
Vente planifiée
|
Beck John W
Chief Financial Officer
Dirigeant
|
400
-100.0%
8,01
3 204 USD
|
400
-100.0%
|
8,01
|
3 204 USD
|
|
|
2007-06-05 |
2007-06-01 |
VP
Vente planifiée
|
Beck John W
Chief Financial Officer
Dirigeant
|
9 635
-96.0%
8,00
77 080 USD
|
9 635
-96.0%
|
8,00
|
77 080 USD
|
|
|
2007-05-24 |
2007-05-22 |
VP
Vente planifiée
|
Beck John W
Chief Financial Officer
Dirigeant
|
300
-0.1%
8,00
2 400 USD
|
300
-0.1%
|
8,00
|
2 400 USD
|
|
|
2007-04-25 |
2007-04-25 |
VP
Vente planifiée
|
Beck John W
Chief Financial Officer
Dirigeant
|
3 300
-1.4%
8,13
26 829 USD
|
3 300
-1.4%
|
8,13
|
26 829 USD
|
|
|
2007-04-25 |
2007-04-24 |
VP
Vente planifiée
|
Baracchini Edgardo Jr
Sr. VP of Business Development
Dirigeant
|
1 800
-37.4%
8,24
14 832 USD
|
1 800
-37.4%
|
8,24
|
14 832 USD
|
|
|
2007-04-25 |
2007-04-24 |
VP
Vente planifiée
|
Baracchini Edgardo Jr
Sr. VP of Business Development
Dirigeant
|
2 500
-34.2%
8,18
20 450 USD
|
2 500
-34.2%
|
8,18
|
20 450 USD
|
|
|
2007-04-10 |
2007-04-10 |
VP
Vente planifiée
|
Beck John W
Chief Financial Officer
Dirigeant
|
6 172
-38.1%
8,00
49 376 USD
|
6 172
-38.1%
|
8,00
|
49 376 USD
|
|
|
2007-04-10 |
2007-04-09 |
VP
Vente planifiée
|
Beck John W
Chief Financial Officer
Dirigeant
|
1 828
-10.1%
8,00
14 624 USD
|
1 828
-10.1%
|
8,00
|
14 624 USD
|
|
|
2007-02-28 |
2007-02-26 |
VP
Vente planifiée
|
Baracchini Edgardo Jr
Sr. VP of Business Development
Dirigeant
|
700
-8.7%
8,00
5 600 USD
|
700
-8.7%
|
8,00
|
5 600 USD
|
|
|
2007-02-27 |
2007-02-26 |
VP
Vente planifiée
|
Beck John W
Chief Financial Officer
Dirigeant
|
3 300
-1.3%
8,00
26 400 USD
|
3 300
-1.3%
|
8,00
|
26 400 USD
|
|
|
2006-12-05 |
2006-12-05 |
VP
Vente planifiée
|
Beck John W
Chief Financial Officer
Dirigeant
|
3 000
-32.1%
8,00
24 000 USD
|
3 000
-32.1%
|
8,00
|
24 000 USD
|
|
|
2006-12-05 |
2006-12-05 |
VP
Vente planifiée
|
Beck John W
Chief Financial Officer
Dirigeant
|
3 000
-32.1%
8,00
24 000 USD
|
3 000
-32.1%
|
8,00
|
24 000 USD
|
|
|
2006-12-05 |
2006-12-05 |
VP
Vente planifiée
|
Beck John W
Chief Financial Officer
Dirigeant
|
3 000
-32.1%
8,00
24 000 USD
|
3 000
-32.1%
|
8,00
|
24 000 USD
|
|
|
2006-11-29 |
2006-11-27 |
VP
Vente planifiée
|
Beck John W
CFO
Dirigeant
|
100
-0.0%
8,00
800 USD
|
100
-0.0%
|
8,00
|
800 USD
|
|
|
2006-11-29 |
2006-11-27 |
VP
Vente planifiée
|
Beck John W
CFO
Dirigeant
|
200
-0.1%
8,01
1 602 USD
|
200
-0.1%
|
8,01
|
1 602 USD
|
|
|
2006-11-29 |
2006-11-27 |
VP
Vente planifiée
|
Beck John W
CFO
Dirigeant
|
200
-0.1%
8,02
1 604 USD
|
200
-0.1%
|
8,02
|
1 604 USD
|
|
|
2006-11-13 |
2006-11-08 |
VP
Vente planifiée
|
Beck John W
Sr. VP, Finance & CFO
Dirigeant
|
3 000
-24.3%
8,00
24 000 USD
|
3 000
-24.3%
|
8,00
|
24 000 USD
|
|
|
2006-11-13 |
2006-11-08 |
VP
Vente planifiée
|
Beck John W
Sr. VP, Finance & CFO
Dirigeant
|
3 000
-24.3%
8,00
24 000 USD
|
3 000
-24.3%
|
8,00
|
24 000 USD
|
|
|
2006-11-13 |
2006-11-08 |
VP
Vente planifiée
|
Beck John W
Sr. VP, Finance & CFO
Dirigeant
|
3 000
-24.3%
8,00
24 000 USD
|
3 000
-24.3%
|
8,00
|
24 000 USD
|
|
|
2006-11-07 |
2006-11-03 |
A
Achat
|
CREDIT SUISSE/
Actionnaire important
|
527 000
+17.4%
7,17
3 776 324 USD
|
527 000
+17.4%
|
7,17
|
3 776 324 USD
|
|
|
2006-06-28 |
2006-06-26 |
VP
Vente planifiée
|
Baracchini Edgardo Jr
Sr. VP, Business Development
Dirigeant
|
250
-21.9%
8,35
2 088 USD
|
250
-21.9%
|
8,35
|
2 088 USD
|
|
|
2006-06-28 |
2006-06-26 |
VP
Vente planifiée
|
Baracchini Edgardo Jr
Sr. VP, Business Development
Dirigeant
|
250
-21.9%
8,35
2 088 USD
|
250
-21.9%
|
8,35
|
2 088 USD
|
|
|
2006-05-24 |
2006-05-22 |
A
Achat
|
CASH HARVEY B
Actionnaire important
|
39 836
+391.9%
8,02
319 648 USD
|
39 836
+391.9%
|
8,02
|
319 648 USD
|
|
|
2006-05-24 |
2006-05-19 |
A
Achat
|
CASH HARVEY B
Actionnaire important
|
5 000
+96.8%
8,10
40 500 USD
|
5 000
+96.8%
|
8,10
|
40 500 USD
|
|
|
2006-05-24 |
2006-05-18 |
A
Achat
|
CASH HARVEY B
Actionnaire important
|
700
+15.7%
8,10
5 670 USD
|
700
+15.7%
|
8,10
|
5 670 USD
|
|
|
2006-05-24 |
2006-05-16 |
A
Achat
|
CASH HARVEY B
Actionnaire important
|
4 464
+inf%
8,00
35 706 USD
|
4 464
+inf%
|
8,00
|
35 706 USD
|
|
|
2007-03-09 |
2006-03-01 |
VP
Vente planifiée
|
Beck John W
Chief Financial Officer
Dirigeant
|
1 000
-5.3%
8,00
8 000 USD
|
1 000
-5.3%
|
8,00
|
8 000 USD
|
|
|
2005-10-04 |
2005-09-30 |
A
Achat
|
CREDIT SUISSE/
Actionnaire important
|
341 297
+20.7%
5,86
2 000 000 USD
|
341 297
+20.7%
|
5,86
|
2 000 000 USD
|
|
|
2005-10-04 |
2005-09-30 |
A
Achat
|
INTERWEST PARTNERS VII L P
Actionnaire important
|
19 497
+19.4%
5,86
114 252 USD
|
19 497
+19.4%
|
5,86
|
114 252 USD
|
|
|
2005-10-04 |
2005-09-30 |
A
Achat
|
INTERWEST PARTNERS VII L P
Actionnaire important
|
407 124
+19.4%
5,86
2 385 747 USD
|
407 124
+19.4%
|
5,86
|
2 385 747 USD
|
|
|
2005-10-04 |
2005-09-30 |
A
Achat
|
ORONSKY ARNOLD L
Administrateur non-exécutif
Actionnaire important
|
19 497
+19.4%
5,86
114 252 USD
|
19 497
+19.4%
|
5,86
|
114 252 USD
|
|
|
2005-10-04 |
2005-09-30 |
A
Achat
|
ORONSKY ARNOLD L
Administrateur non-exécutif
Actionnaire important
|
407 124
+19.4%
5,86
2 385 747 USD
|
407 124
+19.4%
|
5,86
|
2 385 747 USD
|
|
|
2005-11-04 |
2005-09-07 |
A
Achat
|
Gschwend Heinz W
Administrateur non-exécutif
|
2 000
+5.7%
4,00
8 000 USD
|
2 000
+5.7%
|
4,00
|
8 000 USD
|
|
|
2005-11-04 |
2005-08-22 |
A
Achat
|
Gschwend Heinz W
Administrateur non-exécutif
|
3 000
+9.4%
4,36
13 080 USD
|
3 000
+9.4%
|
4,36
|
13 080 USD
|
|
|
2005-01-24 |
2004-12-22 |
A
Achat
|
ORONSKY ARNOLD L
Administrateur non-exécutif
Actionnaire important
|
500
+inf%
6,84
3 420 USD
|
500
+inf%
|
6,84
|
3 420 USD
|
|
|
2004-06-23 |
2004-06-21 |
A
Achat
|
INTERWEST PARTNERS VII L P
Actionnaire important
|
5 941
+inf%
7,00
41 587 USD
|
5 941
+inf%
|
7,00
|
41 587 USD
|
|
|
2004-06-23 |
2004-06-21 |
A
Achat
|
INTERWEST PARTNERS VII L P
Actionnaire important
|
124 059
+inf%
7,00
868 413 USD
|
124 059
+inf%
|
7,00
|
868 413 USD
|
|
|
2004-06-23 |
2004-06-21 |
A
Achat
|
INTERWEST PARTNERS VII L P
Actionnaire important
|
5 941
+inf%
7,00
41 587 USD
|
5 941
+inf%
|
7,00
|
41 587 USD
|
|
|
2004-06-23 |
2004-06-21 |
A
Achat
|
INTERWEST PARTNERS VII L P
Actionnaire important
|
124 059
+inf%
7,00
868 413 USD
|
124 059
+inf%
|
7,00
|
868 413 USD
|
|
|
2004-06-23 |
2004-06-21 |
A
Achat
|
ORONSKY ARNOLD L
Administrateur non-exécutif
Actionnaire important
|
5 941
+inf%
7,00
41 587 USD
|
5 941
+inf%
|
7,00
|
41 587 USD
|
|
|
2004-06-23 |
2004-06-21 |
A
Achat
|
ORONSKY ARNOLD L
Administrateur non-exécutif
Actionnaire important
|
124 059
+inf%
7,00
868 413 USD
|
124 059
+inf%
|
7,00
|
868 413 USD
|
|
|
2004-06-21 |
2004-06-21 |
A
Achat
|
MPM BIOVENTURES II QP LP
Actionnaire important
|
357 000
+10.4%
7,00
2 499 000 USD
|
357 000
+10.4%
|
7,00
|
2 499 000 USD
|
|
|
2004-06-21 |
2004-06-21 |
A
Achat
|
EVNIN LUKE
Administrateur non-exécutif
Actionnaire important
|
357 000
+10.4%
7,00
2 499 000 USD
|
357 000
+10.4%
|
7,00
|
2 499 000 USD
|
|
