2008-12-11 |
2008-12-08 |
V
Vente
|
GREAT POINT PARTNERS LLC
Actionnaire important
|
19 418
-0.5%
0,59
11 457 USD
|
19 418
-0.5%
|
0,59
|
11 457 USD
|
|
2008-12-11 |
2008-12-08 |
V
Vente
|
GREAT POINT PARTNERS LLC
Actionnaire important
|
22 797
-0.5%
0,59
13 450 USD
|
22 797
-0.5%
|
0,59
|
13 450 USD
|
|
2008-12-11 |
2008-12-05 |
V
Vente
|
GREAT POINT PARTNERS LLC
Actionnaire important
|
449 523
-9.9%
0,59
265 219 USD
|
449 523
-9.9%
|
0,59
|
265 219 USD
|
|
2008-12-11 |
2008-12-05 |
V
Vente
|
GREAT POINT PARTNERS LLC
Actionnaire important
|
527 702
-9.9%
0,59
311 344 USD
|
527 702
-9.9%
|
0,59
|
311 344 USD
|
|
2007-11-30 |
2007-11-28 |
A
Achat
|
FLEMING JONATHAN
Administrateur non-exécutif
|
990 066
+38.0%
0,55
544 536 USD
|
990 066
+38.0%
|
0,55
|
544 536 USD
|
|
2007-11-30 |
2007-11-28 |
A
Achat
|
FLEMING JONATHAN
Administrateur non-exécutif
|
9 934
+38.0%
0,55
5 464 USD
|
9 934
+38.0%
|
0,55
|
5 464 USD
|
|
2007-11-06 |
2007-11-05 |
V
Vente
|
GREAT POINT PARTNERS LLC
Actionnaire important
|
11 868
-0.3%
0,98
11 631 USD
|
11 868
-0.3%
|
0,98
|
11 631 USD
|
|
2007-11-06 |
2007-11-05 |
V
Vente
|
GREAT POINT PARTNERS LLC
Actionnaire important
|
13 932
-0.3%
0,98
13 653 USD
|
13 932
-0.3%
|
0,98
|
13 653 USD
|
|
2007-11-06 |
2007-11-02 |
V
Vente
|
GREAT POINT PARTNERS LLC
Actionnaire important
|
162 840
-3.5%
1,02
166 895 USD
|
162 840
-3.5%
|
1,02
|
166 895 USD
|
|
2007-11-06 |
2007-11-02 |
V
Vente
|
GREAT POINT PARTNERS LLC
Actionnaire important
|
191 160
-3.5%
1,02
195 920 USD
|
191 160
-3.5%
|
1,02
|
195 920 USD
|
|
2007-10-24 |
2007-10-23 |
V
Vente
|
GREAT POINT PARTNERS LLC
Actionnaire important
|
108 000
-1.9%
0,91
98 215 USD
|
108 000
-1.9%
|
0,91
|
98 215 USD
|
|
2007-10-24 |
2007-10-22 |
V
Vente
|
GREAT POINT PARTNERS LLC
Actionnaire important
|
92 000
-1.9%
0,91
83 665 USD
|
92 000
-1.9%
|
0,91
|
83 665 USD
|
|
2007-10-24 |
2007-10-22 |
V
Vente
|
GREAT POINT PARTNERS LLC
Actionnaire important
|
191 360
-3.8%
0,95
181 677 USD
|
191 360
-3.8%
|
0,95
|
181 677 USD
|
|
2007-10-24 |
2007-10-22 |
V
Vente
|
GREAT POINT PARTNERS LLC
Actionnaire important
|
224 640
-3.8%
0,95
213 273 USD
|
224 640
-3.8%
|
0,95
|
213 273 USD
|
|
2007-10-22 |
2007-10-17 |
V
Vente
|
GREAT POINT PARTNERS LLC
Actionnaire important
|
41 400
-0.8%
0,97
40 158 USD
|
41 400
-0.8%
|
0,97
|
40 158 USD
|
|
2007-10-22 |
2007-10-17 |
V
Vente
|
GREAT POINT PARTNERS LLC
Actionnaire important
|
353 740
-6.6%
0,94
334 107 USD
|
353 740
-6.6%
|
0,94
|
334 107 USD
|
|
2007-10-22 |
2007-10-17 |
V
Vente
|
GREAT POINT PARTNERS LLC
Actionnaire important
|
48 600
-0.8%
0,97
47 142 USD
|
48 600
-0.8%
|
0,97
|
47 142 USD
|
|
2007-10-22 |
2007-10-17 |
V
Vente
|
GREAT POINT PARTNERS LLC
Actionnaire important
|
415 260
-6.6%
0,94
392 213 USD
|
415 260
-6.6%
|
0,94
|
392 213 USD
|
|
2007-10-17 |
2007-10-16 |
V
Vente
|
GREAT POINT PARTNERS LLC
Actionnaire important
|
177 495
-3.2%
1,01
180 051 USD
|
177 495
-3.2%
|
1,01
|
180 051 USD
|
|
2007-10-17 |
2007-10-16 |
V
Vente
|
GREAT POINT PARTNERS LLC
Actionnaire important
|
138 000
-2.4%
1,11
153 235 USD
|
138 000
-2.4%
|
1,11
|
153 235 USD
|
|
2007-10-17 |
2007-10-16 |
V
Vente
|
GREAT POINT PARTNERS LLC
Actionnaire important
|
208 364
-3.2%
1,01
211 364 USD
|
208 364
-3.2%
|
1,01
|
211 364 USD
|
|
2007-10-17 |
2007-10-16 |
V
Vente
|
GREAT POINT PARTNERS LLC
Actionnaire important
|
162 000
-2.4%
0,98
158 760 USD
|
162 000
-2.4%
|
0,98
|
158 760 USD
|
|
2007-10-17 |
2007-10-15 |
V
Vente
|
GREAT POINT PARTNERS LLC
Actionnaire important
|
619 397
-9.8%
0,98
607 009 USD
|
619 397
-9.8%
|
0,98
|
607 009 USD
|
|
2007-10-17 |
2007-10-15 |
V
Vente
|
GREAT POINT PARTNERS LLC
Actionnaire important
|
15 686
-0.2%
1,10
17 273 USD
|
15 686
-0.2%
|
1,10
|
17 273 USD
|
|
2007-10-17 |
2007-10-15 |
V
Vente
|
GREAT POINT PARTNERS LLC
Actionnaire important
|
727 119
-9.8%
1,11
807 393 USD
|
727 119
-9.8%
|
1,11
|
807 393 USD
|
|
2007-10-17 |
2007-10-15 |
V
Vente
|
GREAT POINT PARTNERS LLC
Actionnaire important
|
18 484
-0.2%
1,10
20 364 USD
|
18 484
-0.2%
|
1,10
|
20 364 USD
|
|
2007-09-18 |
2007-09-14 |
V
Vente
|
MPM BioVentures IV QP LP
Actionnaire important
|
27 600
-0.2%
2,10
57 960 USD
|
27 600
-0.2%
|
2,10
|
57 960 USD
|
|
2007-09-18 |
2007-09-14 |
V
Vente
|
KAILIAN VAUGHN M
Administrateur non-exécutif
Actionnaire important
|
27 600
-0.2%
2,10
57 960 USD
|
27 600
-0.2%
|
2,10
|
57 960 USD
|
|
2007-09-14 |
2007-09-13 |
V
Vente
|
KAILIAN VAUGHN M
Administrateur non-exécutif
Actionnaire important
|
62 180
-0.4%
2,12
132 120 USD
|
62 180
-0.4%
|
2,12
|
132 120 USD
|
|
2007-09-14 |
2007-09-13 |
V
Vente
|
MPM BioVentures IV QP LP
Actionnaire important
|
62 180
-0.4%
2,12
132 120 USD
|
62 180
-0.4%
|
2,12
|
132 120 USD
|
|
2007-09-14 |
2007-09-12 |
V
Vente
|
KAILIAN VAUGHN M
Administrateur non-exécutif
Actionnaire important
|
10 000
-0.1%
2,16
21 611 USD
|
10 000
-0.1%
|
2,16
|
21 611 USD
|
|
2007-09-14 |
2007-09-12 |
V
Vente
|
MPM BioVentures IV QP LP
Actionnaire important
|
10 000
-0.1%
2,16
21 611 USD
|
10 000
-0.1%
|
2,16
|
21 611 USD
|
|
2007-01-05 |
2006-12-18 |
A
Achat
|
KAILIAN VAUGHN M
Administrateur non-exécutif
Actionnaire important
|
2 315 151
+25.5%
1,11
2 569 818 USD
|
2 315 151
+25.5%
|
1,11
|
2 569 818 USD
|
|
2007-01-05 |
2006-12-18 |
A
Achat
|
MPM BioVentures IV LP
Actionnaire important
|
2 315 151
+25.5%
1,11
2 569 818 USD
|
2 315 151
+25.5%
|
1,11
|
2 569 818 USD
|
|
2006-10-18 |
2006-10-16 |
A
Achat
|
EVNIN ANTHONY B
Administrateur non-exécutif
|
516 977
+42.6%
1,11
573 844 USD
|
516 977
+42.6%
|
1,11
|
573 844 USD
|
|
2006-10-18 |
2006-10-16 |
A
Achat
|
EVNIN ANTHONY B
Administrateur non-exécutif
|
359 255
+41.8%
1,11
398 773 USD
|
359 255
+41.8%
|
1,11
|
398 773 USD
|
|
2006-10-18 |
2006-10-16 |
A
Achat
|
EVNIN ANTHONY B
Administrateur non-exécutif
|
87 623
+47.6%
1,11
97 262 USD
|
87 623
+47.6%
|
1,11
|
97 262 USD
|
|
2006-10-18 |
2006-10-16 |
A
Achat
|
SULAT JAMES R
President & CEO
Administrateur exécutif
|
87 623
+52.2%
1,11
97 262 USD
|
87 623
+52.2%
|
1,11
|
97 262 USD
|
|
2006-10-18 |
2006-10-16 |
A
Achat
|
MEYERS MICHAEL E
Administrateur non-exécutif
|
17 525
+66.6%
1,11
19 453 USD
|
17 525
+66.6%
|
1,11
|
19 453 USD
|
|
2006-06-12 |
2006-06-09 |
V
Vente
|
MARXE AUSTIN W & GREENHOUSE DAVID M
Actionnaire important
|
12 000
-0.3%
1,76
21 140 USD
|
12 000
-0.3%
|
1,76
|
21 140 USD
|
|
2006-06-12 |
2006-06-08 |
V
Vente
|
MARXE AUSTIN W & GREENHOUSE DAVID M
Actionnaire important
|
3 567
-0.1%
1,66
5 921 USD
|
3 567
-0.1%
|
1,66
|
5 921 USD
|
|
2006-06-12 |
2006-06-08 |
V
Vente
|
MARXE AUSTIN W & GREENHOUSE DAVID M
Actionnaire important
|
14 300
-0.4%
1,78
25 470 USD
|
14 300
-0.4%
|
1,78
|
25 470 USD
|
|
2006-06-12 |
2006-06-08 |
V
Vente
|
MARXE AUSTIN W & GREENHOUSE DAVID M
Actionnaire important
|
196 500
-5.0%
1,67
328 587 USD
|
196 500
-5.0%
|
1,67
|
328 587 USD
|
|
2006-06-06 |
2006-06-05 |
A
Achat
|
SULAT JAMES R
President & CEO
Administrateur exécutif
|
10 000
+6.3%
1,75
17 500 USD
|
10 000
+6.3%
|
1,75
|
17 500 USD
|
|
2006-06-05 |
2006-06-01 |
V
Vente
|
MARXE AUSTIN W & GREENHOUSE DAVID M
Actionnaire important
|
15 600
-0.4%
1,86
29 016 USD
|
15 600
-0.4%
|
1,86
|
29 016 USD
|
|
2006-06-05 |
2006-06-01 |
V
Vente
|
MARXE AUSTIN W & GREENHOUSE DAVID M
Actionnaire important
|
3 400
-0.1%
1,91
6 496 USD
|
3 400
-0.1%
|
1,91
|
6 496 USD
|
|
2006-05-17 |
2006-05-15 |
V
Vente
|
MARXE AUSTIN W & GREENHOUSE DAVID M
Actionnaire important
|
14 400
-0.4%
2,00
28 793 USD
|
14 400
-0.4%
|
2,00
|
28 793 USD
|
|
2006-05-15 |
2006-05-12 |
V
Vente
|
MARXE AUSTIN W & GREENHOUSE DAVID M
Actionnaire important
|
24 000
-0.6%
2,02
48 439 USD
|
24 000
-0.6%
|
2,02
|
48 439 USD
|
|
2006-05-15 |
2006-05-11 |
V
Vente
|
MARXE AUSTIN W & GREENHOUSE DAVID M
Actionnaire important
|
112 000
-2.7%
2,15
240 509 USD
|
112 000
-2.7%
|
2,15
|
240 509 USD
|
|
2005-09-27 |
2005-09-23 |
A
Achat
|
MARDUEL ALIX
No longer a Director
|
789 474
0,00
0 USD
|
789 474
|
0,00
|
0 USD
|
|
2005-09-26 |
2005-09-23 |
A
Achat
|
EVNIN ANTHONY B
Administrateur non-exécutif
|
465 789
+62.3%
1,90
884 999 USD
|
465 789
+62.3%
|
1,90
|
884 999 USD
|
|
2005-09-26 |
2005-09-23 |
A
Achat
|
EVNIN ANTHONY B
Administrateur non-exécutif
|
323 684
+60.4%
1,90
615 000 USD
|
323 684
+60.4%
|
1,90
|
615 000 USD
|
|
2005-09-26 |
2005-09-23 |
A
Achat
|
EVNIN ANTHONY B
Administrateur non-exécutif
|
184 211
+inf%
1,90
350 001 USD
|
184 211
+inf%
|
1,90
|
350 001 USD
|
|
2005-09-23 |
2005-09-23 |
A
Achat
|
SULAT JAMES R
President & CEO
Administrateur exécutif
|
157 895
+inf%
1,90
300 001 USD
|
157 895
+inf%
|
1,90
|
300 001 USD
|
|
2005-09-23 |
2005-09-23 |
A
Achat
|
FLEMING JONATHAN
Administrateur non-exécutif
Actionnaire important
|
26 142
+inf%
1,90
49 670 USD
|
26 142
+inf%
|
1,90
|
49 670 USD
|
|
2005-09-23 |
2005-09-23 |
A
Achat
|
FLEMING JONATHAN
Administrateur non-exécutif
Actionnaire important
|
2 605 437
+inf%
1,90
4 950 330 USD
|
2 605 437
+inf%
|
1,90
|
4 950 330 USD
|
|
2005-09-23 |
2005-09-23 |
A
Achat
|
FLEMING JONATHAN
Administrateur non-exécutif
Actionnaire important
|
526 316
+69.5%
1,90
1 000 000 USD
|
526 316
+69.5%
|
1,90
|
1 000 000 USD
|
|
2005-09-23 |
2005-09-23 |
A
Achat
|
KRIEBEL ROBERT I
Administrateur non-exécutif
|
5 000
+inf%
1,90
9 500 USD
|
5 000
+inf%
|
1,90
|
9 500 USD
|
|
2005-09-23 |
2005-09-23 |
A
Achat
|
MEYERS MICHAEL E
Administrateur non-exécutif
|
26 316
+inf%
1,90
50 000 USD
|
26 316
+inf%
|
1,90
|
50 000 USD
|
|
2005-09-23 |
2005-09-23 |
A
Achat
|
SCULLION TONY
President & CEO
Administrateur exécutif
|
39 474
+28.5%
1,90
75 001 USD
|
39 474
+28.5%
|
1,90
|
75 001 USD
|
|
2005-09-23 |
2005-09-23 |
A
Achat
|
Lowe David A
Chief Scientific Officer
Administrateur exécutif
|
26 316
+inf%
1,90
50 000 USD
|
26 316
+inf%
|
1,90
|
50 000 USD
|
|
2005-09-23 |
2005-09-23 |
A
Achat
|
GILBERT WALTER PHD
Administrateur non-exécutif
|
52 632
+39.5%
1,90
100 001 USD
|
52 632
+39.5%
|
1,90
|
100 001 USD
|
|
2005-03-16 |
2005-03-14 |
VP
Vente planifiée
|
SCULLION TONY
Chief Executive Officer
Administrateur exécutif
|
300
-0.3%
5,00
1 500 USD
|
300
-0.3%
|
5,00
|
1 500 USD
|
|
2005-03-09 |
2005-03-07 |
VP
Vente planifiée
|
SCULLION TONY
Chief Executive Officer
Administrateur exécutif
|
8 750
-7.8%
5,01
43 870 USD
|
8 750
-7.8%
|
5,01
|
43 870 USD
|
|
2005-03-03 |
2005-03-01 |
VP
Vente planifiée
|
SCULLION TONY
Chief Executive Officer
Administrateur exécutif
|
8 750
-8.2%
5,01
43 806 USD
|
8 750
-8.2%
|
5,01
|
43 806 USD
|
|
2005-02-24 |
2005-02-22 |
VP
Vente planifiée
|
SCULLION TONY
Chief Executive Officer
Administrateur exécutif
|
8 750
-8.8%
5,00
43 750 USD
|
8 750
-8.8%
|
5,00
|
43 750 USD
|
|
2005-02-15 |
2005-02-14 |
VP
Vente planifiée
|
SCULLION TONY
Chief Executive Officer
Administrateur exécutif
|
8 750
-8.8%
5,01
43 870 USD
|
8 750
-8.8%
|
5,01
|
43 870 USD
|
|
2005-02-09 |
2005-02-07 |
VP
Vente planifiée
|
SCULLION TONY
Chief Executive Officer
Administrateur exécutif
|
8 750
-8.8%
5,00
43 750 USD
|
8 750
-8.8%
|
5,00
|
43 750 USD
|
|
2005-02-04 |
2005-02-02 |
VP
Vente planifiée
|
SCULLION TONY
Chief Executive Officer
Administrateur exécutif
|
8 750
-8.8%
5,00
43 750 USD
|
8 750
-8.8%
|
5,00
|
43 750 USD
|
|
2005-01-26 |
2005-01-25 |
VP
Vente planifiée
|
SCULLION TONY
Chief Executive Officer
Administrateur exécutif
|
2 450
-2.6%
5,00
12 250 USD
|
2 450
-2.6%
|
5,00
|
12 250 USD
|
|
2005-01-26 |
2005-01-24 |
VP
Vente planifiée
|
SCULLION TONY
Chief Executive Officer
Administrateur exécutif
|
6 300
-6.5%
5,03
31 675 USD
|
6 300
-6.5%
|
5,03
|
31 675 USD
|
|
2005-01-20 |
2005-01-18 |
VP
Vente planifiée
|
SCULLION TONY
Chief Executive Officer
Administrateur exécutif
|
8 750
-8.8%
5,02
43 954 USD
|
8 750
-8.8%
|
5,02
|
43 954 USD
|
|
2005-01-12 |
2005-01-11 |
VP
Vente planifiée
|
SCULLION TONY
Chief Executive Officer
Administrateur exécutif
|
4 000
-4.2%
5,41
21 625 USD
|
4 000
-4.2%
|
5,41
|
21 625 USD
|
|
2005-01-12 |
2005-01-10 |
VP
Vente planifiée
|
SCULLION TONY
Chief Executive Officer
Administrateur exécutif
|
4 750
-5.0%
5,48
26 042 USD
|
4 750
-5.0%
|
5,48
|
26 042 USD
|
|
2005-01-05 |
2005-01-05 |
VP
Vente planifiée
|
SCULLION TONY
Chief Executive Officer
Administrateur exécutif
|
1 750
-1.9%
5,44
9 520 USD
|
1 750
-1.9%
|
5,44
|
9 520 USD
|
|