|
2025-03-06 |
2025-03-06 |
V
Vente
|
DENNER ALEXANDER J
Actionnaire important
|
1 196 746
-17.5%
17,52
20 964 237 USD
|
1 196 746
-17.5%
|
17,52
|
20 964 237 USD
|
|
|
2025-03-06 |
2025-03-05 |
V
Vente
|
DENNER ALEXANDER J
Actionnaire important
|
270 374
-3.8%
17,63
4 766 126 USD
|
270 374
-3.8%
|
17,63
|
4 766 126 USD
|
|
|
2025-03-06 |
2025-03-04 |
V
Vente
|
DENNER ALEXANDER J
Actionnaire important
|
151 175
-2.1%
17,63
2 665 079 USD
|
151 175
-2.1%
|
17,63
|
2 665 079 USD
|
|
|
2023-11-17 |
2023-11-15 |
V
Vente
|
Zhen Marianne
Chief Accounting Officer
Dirigeant
|
5 405
-11.9%
13,97
75 508 USD
|
5 405
-11.9%
|
13,97
|
75 508 USD
|
|
|
2023-11-17 |
2023-11-15 |
V
Vente
|
Zhen Marianne
Chief Accounting Officer
Dirigeant
|
5 589
-10.9%
14,01
78 302 USD
|
5 589
-10.9%
|
14,01
|
78 302 USD
|
|
|
2023-06-20 |
2023-06-15 |
A
Achat
|
DENNER ALEXANDER J
Actionnaire important
|
62 000
+0.9%
13,13
814 196 USD
|
62 000
+0.9%
|
13,13
|
814 196 USD
|
|
|
2023-06-07 |
2023-06-06 |
A
Achat
|
DENNER ALEXANDER J
Actionnaire important
|
8 000
+0.1%
13,05
104 384 USD
|
8 000
+0.1%
|
13,05
|
104 384 USD
|
|
|
2023-06-07 |
2023-06-05 |
A
Achat
|
DENNER ALEXANDER J
Actionnaire important
|
7 000
+0.1%
13,04
91 297 USD
|
7 000
+0.1%
|
13,04
|
91 297 USD
|
|
|
2023-05-30 |
2023-05-30 |
A
Achat
|
DENNER ALEXANDER J
Actionnaire important
|
120 000
+1.7%
13,01
1 560 648 USD
|
120 000
+1.7%
|
13,01
|
1 560 648 USD
|
|
|
2023-05-30 |
2023-05-26 |
A
Achat
|
DENNER ALEXANDER J
Actionnaire important
|
30 000
+0.4%
13,12
393 729 USD
|
30 000
+0.4%
|
13,12
|
393 729 USD
|
|
|
2023-05-30 |
2023-05-25 |
A
Achat
|
DENNER ALEXANDER J
Actionnaire important
|
50 000
+0.7%
13,09
654 330 USD
|
50 000
+0.7%
|
13,09
|
654 330 USD
|
|
|
2023-05-19 |
2023-05-18 |
A
Achat
|
DENNER ALEXANDER J
Actionnaire important
|
10 000
+0.1%
13,05
130 538 USD
|
10 000
+0.1%
|
13,05
|
130 538 USD
|
|
|
2023-05-19 |
2023-05-17 |
A
Achat
|
DENNER ALEXANDER J
Actionnaire important
|
50 000
+0.7%
13,07
653 690 USD
|
50 000
+0.7%
|
13,07
|
653 690 USD
|
|
|
2023-05-15 |
2023-05-11 |
A
Achat
|
DENNER ALEXANDER J
Actionnaire important
|
290 000
+4.4%
12,34
3 577 411 USD
|
290 000
+4.4%
|
12,34
|
3 577 411 USD
|
|
|
2023-03-14 |
2023-03-10 |
AP
Achat planifié
|
Raifeld Pavel
Chief Executive Officer
Dirigeant
|
3 000
+44.1%
10,87
32 603 USD
|
3 000
+44.1%
|
10,87
|
32 603 USD
|
|
|
2021-05-25 |
2021-05-24 |
A
Achat
|
Bickerstaff George
Administrateur non-exécutif
|
10 000
+8.7%
13,46
134 619 USD
|
10 000
+8.7%
|
13,46
|
134 619 USD
|
|
|
2021-05-25 |
2021-05-21 |
A
Achat
|
Bickerstaff George
Administrateur non-exécutif
|
10 000
+9.6%
12,97
129 670 USD
|
10 000
+9.6%
|
12,97
|
129 670 USD
|
|
|
2021-05-24 |
2021-05-20 |
V
Vente
|
GLAXOSMITHKLINE PLC
Actionnaire important
|
32 005 260
-100.0%
12,25
392 064 435 USD
|
32 005 260
-100.0%
|
12,25
|
392 064 435 USD
|
|
|
2020-02-24 |
2020-02-24 |
V
Vente
|
Zhen Marianne
Chief Accounting Officer
Dirigeant
|
2 954
-11.9%
14,78
43 660 USD
|
2 954
-11.9%
|
14,78
|
43 660 USD
|
|
|
2019-02-28 |
2019-02-27 |
A
Achat
|
Bickerstaff George
Administrateur non-exécutif
|
15 000
+38.7%
15,90
238 500 USD
|
15 000
+38.7%
|
15,90
|
238 500 USD
|
|
|
2019-02-28 |
2019-02-26 |
V
Vente
|
Zhen Marianne
Chief Accounting Officer
Dirigeant
|
5 617
-23.1%
16,00
89 872 USD
|
5 617
-23.1%
|
16,00
|
89 872 USD
|
|
|
2019-02-22 |
2019-02-21 |
A
Achat
|
Bickerstaff George
Administrateur non-exécutif
|
10 000
+34.8%
14,90
148 958 USD
|
10 000
+34.8%
|
14,90
|
148 958 USD
|
|
|
2019-02-20 |
2019-02-15 |
A
Achat
|
HULME GEOFFREY
Interim PEO
Dirigeant
|
7 000
+inf%
14,80
103 600 USD
|
7 000
+inf%
|
14,80
|
103 600 USD
|
|
|
2018-08-22 |
2018-08-21 |
VP
Vente planifiée
|
ABERCROMBIE GEORGE B
Sr. VP & Chief Comm. Officer
Dirigeant
|
8 000
-2.7%
14,11
112 840 USD
|
8 000
-2.7%
|
14,11
|
112 840 USD
|
|
|
2018-08-22 |
2018-08-21 |
V
Vente
|
Witek Theodore J. Jr.
Sr. VP & Chief Scientific Off.
Dirigeant
|
8 504
-3.3%
14,12
120 080 USD
|
8 504
-3.3%
|
14,12
|
120 080 USD
|
|
|
2018-05-22 |
2018-05-21 |
VP
Vente planifiée
|
ABERCROMBIE GEORGE B
Sr. VP & Chief Comm. Officer
Dirigeant
|
8 000
-2.6%
14,40
115 202 USD
|
8 000
-2.6%
|
14,40
|
115 202 USD
|
|
|
2018-05-22 |
2018-05-21 |
VP
Vente planifiée
|
dEsparbes Eric
SVP and CFO
Dirigeant
|
5 808
-1.5%
14,40
83 623 USD
|
5 808
-1.5%
|
14,40
|
83 623 USD
|
|
|
2018-02-22 |
2018-02-21 |
VP
Vente planifiée
|
Witek Theodore J. Jr.
Sr. VP & Chief Scientific Off.
Dirigeant
|
9 890
-5.0%
16,60
164 148 USD
|
9 890
-5.0%
|
16,60
|
164 148 USD
|
|
|
2018-02-22 |
2018-02-21 |
VP
Vente planifiée
|
ABERCROMBIE GEORGE B
Sr. VP & Chief Comm. Officer
Dirigeant
|
8 000
-3.3%
16,51
132 100 USD
|
8 000
-3.3%
|
16,51
|
132 100 USD
|
|
|
2018-02-22 |
2018-02-21 |
VP
Vente planifiée
|
dEsparbes Eric
Interim PEO, SVP and CFO
Dirigeant
|
5 378
-1.8%
16,52
88 825 USD
|
5 378
-1.8%
|
16,52
|
88 825 USD
|
|
|
2017-12-05 |
2017-12-04 |
V
Vente
|
Aguiar Michael W
President & Chief Exec Officer
Administrateur exécutif
|
12 022
-1.2%
13,13
157 791 USD
|
12 022
-1.2%
|
13,13
|
157 791 USD
|
|
|
2017-11-22 |
2017-11-21 |
VP
Vente planifiée
|
Witek Theodore J. Jr.
Sr. VP & Chief Scientific Off.
|
13 000
-5.7%
13,29
172 795 USD
|
13 000
-5.7%
|
13,29
|
172 795 USD
|
|
|
2017-11-22 |
2017-11-21 |
VP
Vente planifiée
|
ABERCROMBIE GEORGE B
Sr. VP & Chief Comm. Officer
|
5 215
-2.0%
13,26
69 145 USD
|
5 215
-2.0%
|
13,26
|
69 145 USD
|
|
|
2017-11-22 |
2017-11-21 |
VP
Vente planifiée
|
dEsparbes Eric
SVP and CFO
|
13 460
-4.0%
13,31
179 171 USD
|
13 460
-4.0%
|
13,31
|
179 171 USD
|
|
|
2017-11-22 |
2017-11-20 |
VP
Vente planifiée
|
dEsparbes Eric
SVP and CFO
|
1 825
-0.5%
13,04
23 798 USD
|
1 825
-0.5%
|
13,04
|
23 798 USD
|
|
|
2017-08-22 |
2017-08-21 |
VP
Vente planifiée
|
dEsparbes Eric
SVP and CFO
|
1 825
-0.5%
12,20
22 265 USD
|
1 825
-0.5%
|
12,20
|
22 265 USD
|
|
|
2017-05-23 |
2017-05-22 |
VP
Vente planifiée
|
Witek Theodore J. Jr.
Sr. VP & Chief Scientific Off.
Dirigeant
|
7 815
-3.1%
12,01
93 858 USD
|
7 815
-3.1%
|
12,01
|
93 858 USD
|
|
|
2017-05-23 |
2017-05-22 |
VP
Vente planifiée
|
dEsparbes Eric
SVP and CFO
Dirigeant
|
1 825
-0.5%
11,85
21 626 USD
|
1 825
-0.5%
|
11,85
|
21 626 USD
|
|
|
2017-02-22 |
2017-02-21 |
VP
Vente planifiée
|
dEsparbes Eric
SVP and CFO
Dirigeant
|
1 825
-0.5%
12,07
22 028 USD
|
1 825
-0.5%
|
12,07
|
22 028 USD
|
|
|
2016-11-22 |
2016-11-22 |
VP
Vente planifiée
|
WITEK THEODORE L JR
Sr. VP & Chief Scientific Off.
Dirigeant
|
3 700
-2.4%
10,84
40 123 USD
|
3 700
-2.4%
|
10,84
|
40 123 USD
|
|
|
2016-11-22 |
2016-11-21 |
VP
Vente planifiée
|
dEsparbes Eric
SVP and CFO
Dirigeant
|
1 800
-0.8%
10,89
19 602 USD
|
1 800
-0.8%
|
10,89
|
19 602 USD
|
|
|
2016-08-23 |
2016-08-22 |
VP
Vente planifiée
|
dEsparbes Eric
SVP and CFO
Dirigeant
|
3 700
-1.5%
11,77
43 549 USD
|
3 700
-1.5%
|
11,77
|
43 549 USD
|
|
|
2016-05-20 |
2016-05-18 |
VP
Vente planifiée
|
Tyree James L
Administrateur non-exécutif
|
813
-1.6%
10,47
8 512 USD
|
813
-1.6%
|
10,47
|
8 512 USD
|
|
|
2015-05-29 |
2015-05-27 |
V
Vente
|
WALTRIP WILLIAM H
Administrateur non-exécutif
|
16 313
-11.7%
16,32
266 228 USD
|
16 313
-11.7%
|
16,32
|
266 228 USD
|
|
|
2014-08-15 |
2014-08-13 |
V
Vente
|
LEE JUNNING
Sr. VP, Technical Operations
Dirigeant
|
53 424
-16.8%
22,50
1 202 040 USD
|
53 424
-16.8%
|
22,50
|
1 202 040 USD
|
|
|
2014-08-13 |
2014-08-12 |
V
Vente
|
Shafer Bradford J
Sr VP, Gen. Counsel, Secretary
Dirigeant
|
1 048
-0.2%
22,30
23 370 USD
|
1 048
-0.2%
|
22,30
|
23 370 USD
|
|
|
2014-08-13 |
2014-08-11 |
V
Vente
|
Shafer Bradford J
Sr VP, Gen. Counsel, Secretary
Dirigeant
|
27 108
-5.7%
22,12
599 629 USD
|
27 108
-5.7%
|
22,12
|
599 629 USD
|
|
|
2014-03-05 |
2014-03-03 |
VP
Vente planifiée
|
Shafer Bradford J
Sr VP, Gen. Counsel, Secretary
Dirigeant
|
1 800
-0.5%
37,23
67 014 USD
|
1 800
-0.5%
|
37,23
|
67 014 USD
|
|
|
2014-03-05 |
2014-03-03 |
VP
Vente planifiée
|
Shafer Bradford J
Sr VP, Gen. Counsel, Secretary
Dirigeant
|
64 006
-16.3%
36,72
2 350 300 USD
|
64 006
-16.3%
|
36,72
|
2 350 300 USD
|
|
|
2014-02-19 |
2014-02-14 |
VP
Vente planifiée
|
Mammen Mathai
SVP, Research & Early Clin Dev
Dirigeant
|
4 600
-2.4%
40,04
184 184 USD
|
4 600
-2.4%
|
40,04
|
184 184 USD
|
|
|
2013-06-11 |
2013-06-07 |
V
Vente
|
Shafer Bradford J
Sr VP, Gen. Counsel, Secretary
Dirigeant
|
31 038
-9.3%
35,04
1 087 572 USD
|
31 038
-9.3%
|
35,04
|
1 087 572 USD
|
|
|
2013-05-15 |
2013-05-13 |
VP
Vente planifiée
|
Brinkley David L
Head of Business Dev.
Dirigeant
|
16 129
-22.7%
40,33
650 483 USD
|
16 129
-22.7%
|
40,33
|
650 483 USD
|
|
|
2013-05-07 |
2013-05-03 |
VP
Vente planifiée
|
Brinkley David L
Head of Business Dev.
Dirigeant
|
16 129
-22.7%
34,77
560 805 USD
|
16 129
-22.7%
|
34,77
|
560 805 USD
|
|
|
2013-05-02 |
2013-04-30 |
VP
Vente planifiée
|
Mammen Mathai
SVP, Research & Early Clin Dev
Dirigeant
|
200
-0.1%
34,34
6 868 USD
|
200
-0.1%
|
34,34
|
6 868 USD
|
|
|
2013-05-02 |
2013-04-30 |
VP
Vente planifiée
|
Brinkley David L
Head of Business Dev.
Dirigeant
|
100
-0.2%
34,35
3 435 USD
|
100
-0.2%
|
34,35
|
3 435 USD
|
|
|
2013-05-02 |
2013-04-30 |
VP
Vente planifiée
|
Brinkley David L
Head of Business Dev.
Dirigeant
|
17 004
-23.6%
33,76
574 055 USD
|
17 004
-23.6%
|
33,76
|
574 055 USD
|
|
|
2013-05-02 |
2013-04-30 |
VP
Vente planifiée
|
Aguiar Michael W
Sr VP, Chief Financial Officer
Dirigeant
|
10 100
-6.6%
34,34
346 834 USD
|
10 100
-6.6%
|
34,34
|
346 834 USD
|
|
|
2013-05-02 |
2013-04-30 |
VP
Vente planifiée
|
Aguiar Michael W
Sr VP, Chief Financial Officer
Dirigeant
|
160 779
-51.3%
33,77
5 429 507 USD
|
160 779
-51.3%
|
33,77
|
5 429 507 USD
|
|
|
2013-05-02 |
2013-04-30 |
VP
Vente planifiée
|
Winningham Rick E
Chief Executive Officer
Administrateur exécutif
|
1 577
-0.2%
34,32
54 123 USD
|
1 577
-0.2%
|
34,32
|
54 123 USD
|
|
|
2013-05-02 |
2013-04-30 |
VP
Vente planifiée
|
Winningham Rick E
Chief Executive Officer
Administrateur exécutif
|
253 955
-26.0%
33,64
8 543 046 USD
|
253 955
-26.0%
|
33,64
|
8 543 046 USD
|
|
|
2013-02-22 |
2013-02-20 |
VP
Vente planifiée
|
Mammen Mathai
SVP, Research & Early Clin Dev
Dirigeant
|
7 000
-3.2%
22,14
154 980 USD
|
7 000
-3.2%
|
22,14
|
154 980 USD
|
|
|
2012-11-06 |
2012-11-02 |
VP
Vente planifiée
|
Mammen Mathai
SVP, Research & Early Clin Dev
Dirigeant
|
200
-0.1%
22,53
4 506 USD
|
200
-0.1%
|
22,53
|
4 506 USD
|
|
|
2012-08-28 |
2012-08-27 |
VP
Vente planifiée
|
Aguiar Michael W
Sr VP, Chief Financial Officer
Dirigeant
|
2 861
-2.1%
27,86
79 707 USD
|
2 861
-2.1%
|
27,86
|
79 707 USD
|
|
|
2012-08-28 |
2012-08-27 |
VP
Vente planifiée
|
Aguiar Michael W
Sr VP, Chief Financial Officer
Dirigeant
|
17 700
-11.6%
27,24
482 148 USD
|
17 700
-11.6%
|
27,24
|
482 148 USD
|
|
|
2012-08-28 |
2012-08-24 |
VP
Vente planifiée
|
Aguiar Michael W
Sr VP, Chief Financial Officer
Dirigeant
|
4 121
-2.6%
28,01
115 429 USD
|
4 121
-2.6%
|
28,01
|
115 429 USD
|
|
|
2012-08-15 |
2012-08-13 |
VP
Vente planifiée
|
Mammen Mathai
SVP, Research & Early Clin Dev
Dirigeant
|
3 108
-1.4%
26,15
81 274 USD
|
3 108
-1.4%
|
26,15
|
81 274 USD
|
|
|
2012-08-09 |
2012-08-07 |
VP
Vente planifiée
|
Aguiar Michael W
Sr VP, Chief Financial Officer
Dirigeant
|
60 000
-27.5%
27,04
1 622 400 USD
|
60 000
-27.5%
|
27,04
|
1 622 400 USD
|
|
|
2012-08-07 |
2012-08-03 |
VP
Vente planifiée
|
Brinkley David L
Head of Business Dev.
Dirigeant
|
123 917
-65.0%
27,92
3 459 763 USD
|
123 917
-65.0%
|
27,92
|
3 459 763 USD
|
|
|
2012-08-07 |
2012-08-03 |
VP
Vente planifiée
|
Winningham Rick E
Chief Executive Officer
Administrateur exécutif
|
36 200
-5.8%
28,15
1 019 030 USD
|
36 200
-5.8%
|
28,15
|
1 019 030 USD
|
|
|
2012-08-07 |
2012-08-03 |
VP
Vente planifiée
|
Winningham Rick E
Chief Executive Officer
Administrateur exécutif
|
39 549
-5.9%
27,77
1 098 276 USD
|
39 549
-5.9%
|
27,77
|
1 098 276 USD
|
|
|
2012-05-31 |
2012-05-29 |
V
Vente
|
Aguiar Michael W
Sr VP, Chief Financial Officer
Dirigeant
|
20 000
-11.2%
22,29
445 800 USD
|
20 000
-11.2%
|
22,29
|
445 800 USD
|
|
|
2012-05-16 |
2012-05-16 |
A
Achat
|
GLAXOSMITHKLINE PLC
Actionnaire important
|
10 000 000
+63.2%
21,29
212 887 000 USD
|
10 000 000
+63.2%
|
21,29
|
212 887 000 USD
|
|
|
2012-05-02 |
2012-05-01 |
V
Vente
|
DRAZAN JEFFREY M
Administrateur non-exécutif
|
8 586
-20.4%
21,71
186 402 USD
|
8 586
-20.4%
|
21,71
|
186 402 USD
|
|
|
2011-12-13 |
2011-12-09 |
V
Vente
|
Aguiar Michael W
Sr VP, Chief Financial Officer
Dirigeant
|
10 000
-5.1%
21,86
218 600 USD
|
10 000
-5.1%
|
21,86
|
218 600 USD
|
|
|
2011-11-30 |
2011-11-28 |
VP
Vente planifiée
|
Shafer Bradford J
Sr VP, Gen. Counsel, Secretary
Dirigeant
|
20 000
-5.4%
21,00
420 000 USD
|
20 000
-5.4%
|
21,00
|
420 000 USD
|
|
