|
2012-07-13 |
2012-07-13 |
V
Vente
|
ORBIMED ADVISORS LLC
Actionnaire important
|
4 500
-13.9%
2,51
11 298 USD
|
4 500
-13.9%
|
2,51
|
11 298 USD
|
|
|
2012-07-13 |
2012-07-13 |
V
Vente
|
ORBIMED ADVISORS LLC
Actionnaire important
|
474 800
-14.0%
2,51
1 192 033 USD
|
474 800
-14.0%
|
2,51
|
1 192 033 USD
|
|
|
2012-07-13 |
2012-07-12 |
V
Vente
|
ORBIMED ADVISORS LLC
Actionnaire important
|
2 076
-6.0%
2,85
5 916 USD
|
2 076
-6.0%
|
2,85
|
5 916 USD
|
|
|
2012-07-13 |
2012-07-12 |
V
Vente
|
ORBIMED ADVISORS LLC
Actionnaire important
|
218 624
-6.0%
2,85
622 991 USD
|
218 624
-6.0%
|
2,85
|
622 991 USD
|
|
|
2012-07-13 |
2012-07-11 |
V
Vente
|
ORBIMED ADVISORS LLC
Actionnaire important
|
4 792
-12.2%
2,90
13 891 USD
|
4 792
-12.2%
|
2,90
|
13 891 USD
|
|
|
2012-07-13 |
2012-07-11 |
V
Vente
|
ORBIMED ADVISORS LLC
Actionnaire important
|
503 144
-12.2%
2,90
1 458 514 USD
|
503 144
-12.2%
|
2,90
|
1 458 514 USD
|
|
|
2012-03-16 |
2012-03-16 |
V
Vente
|
WAITE CHARLES P JR
Administrateur non-exécutif
Actionnaire important
|
450 000
-24.4%
2,92
1 316 070 USD
|
450 000
-24.4%
|
2,92
|
1 316 070 USD
|
|
|
2012-03-16 |
2012-03-16 |
V
Vente
|
OVP VENTURE PARTNERS VI LP
Actionnaire important
|
450 000
-24.4%
2,92
1 316 070 USD
|
450 000
-24.4%
|
2,92
|
1 316 070 USD
|
|
|
2012-03-16 |
2012-03-15 |
V
Vente
|
WAITE CHARLES P JR
Administrateur non-exécutif
Actionnaire important
|
165 059
-8.2%
2,89
477 136 USD
|
165 059
-8.2%
|
2,89
|
477 136 USD
|
|
|
2012-03-16 |
2012-03-15 |
V
Vente
|
OVP VENTURE PARTNERS VI LP
Actionnaire important
|
165 059
-8.2%
2,89
477 136 USD
|
165 059
-8.2%
|
2,89
|
477 136 USD
|
|
|
2012-03-16 |
2012-03-14 |
V
Vente
|
WAITE CHARLES P JR
Administrateur non-exécutif
Actionnaire important
|
142 941
-6.6%
3,09
441 359 USD
|
142 941
-6.6%
|
3,09
|
441 359 USD
|
|
|
2012-03-16 |
2012-03-14 |
V
Vente
|
OVP VENTURE PARTNERS VI LP
Actionnaire important
|
142 941
-6.6%
3,09
441 359 USD
|
142 941
-6.6%
|
3,09
|
441 359 USD
|
|
|
2012-03-15 |
2012-03-13 |
V
Vente
|
WAITE CHARLES P JR
Administrateur non-exécutif
Actionnaire important
|
275 000
-11.3%
3,20
879 588 USD
|
275 000
-11.3%
|
3,20
|
879 588 USD
|
|
|
2012-03-15 |
2012-03-13 |
V
Vente
|
OVP VENTURE PARTNERS VI LP
Actionnaire important
|
275 000
-11.3%
3,20
879 588 USD
|
275 000
-11.3%
|
3,20
|
879 588 USD
|
|
|
2011-12-16 |
2011-12-14 |
A
Achat
|
SENYEI ANDREW E
Administrateur non-exécutif
Actionnaire important
|
100 000
+99.0%
3,05
305 000 USD
|
100 000
+99.0%
|
3,05
|
305 000 USD
|
|
|
2011-12-16 |
2011-12-14 |
V
Vente
|
OVP VENTURE PARTNERS VI LP
Actionnaire important
|
100 000
-4.0%
3,05
305 000 USD
|
100 000
-4.0%
|
3,05
|
305 000 USD
|
|
|
2011-12-16 |
2011-12-14 |
A
Achat
|
Enterprise Partners Management LLC
Actionnaire important
|
100 000
+99.0%
3,05
305 000 USD
|
100 000
+99.0%
|
3,05
|
305 000 USD
|
|
|
2011-12-16 |
2011-12-14 |
V
Vente
|
WAITE CHARLES P JR
Administrateur non-exécutif
Actionnaire important
|
100 000
-4.0%
3,05
305 000 USD
|
100 000
-4.0%
|
3,05
|
305 000 USD
|
|
|
2011-12-13 |
2011-12-09 |
V
Vente
|
OVP VENTURE PARTNERS VI LP
Actionnaire important
|
21 400
-0.8%
3,00
64 224 USD
|
21 400
-0.8%
|
3,00
|
64 224 USD
|
|
|
2011-12-13 |
2011-12-09 |
V
Vente
|
WAITE CHARLES P JR
Administrateur non-exécutif
Actionnaire important
|
21 400
-0.8%
3,00
64 224 USD
|
21 400
-0.8%
|
3,00
|
64 224 USD
|
|
|
2011-12-09 |
2011-12-08 |
V
Vente
|
WAITE CHARLES P JR
Administrateur non-exécutif
Actionnaire important
|
24 525
-1.0%
3,00
73 685 USD
|
24 525
-1.0%
|
3,00
|
73 685 USD
|
|
|
2011-12-09 |
2011-12-08 |
V
Vente
|
OVP VENTURE PARTNERS VI LP
Actionnaire important
|
24 525
-1.0%
3,00
73 685 USD
|
24 525
-1.0%
|
3,00
|
73 685 USD
|
|
|
2011-12-08 |
2011-12-07 |
V
Vente
|
WAITE CHARLES P JR
Administrateur non-exécutif
Actionnaire important
|
55 420
-2.1%
3,09
171 342 USD
|
55 420
-2.1%
|
3,09
|
171 342 USD
|
|
|
2011-12-08 |
2011-12-07 |
V
Vente
|
OVP VENTURE PARTNERS VI LP
Actionnaire important
|
55 420
-2.1%
3,09
171 342 USD
|
55 420
-2.1%
|
3,09
|
171 342 USD
|
|
|
2011-12-08 |
2011-12-06 |
V
Vente
|
WAITE CHARLES P JR
Administrateur non-exécutif
Actionnaire important
|
42 575
-1.6%
3,13
133 170 USD
|
42 575
-1.6%
|
3,13
|
133 170 USD
|
|
|
2011-12-08 |
2011-12-06 |
V
Vente
|
OVP VENTURE PARTNERS VI LP
Actionnaire important
|
42 575
-1.6%
3,13
133 170 USD
|
42 575
-1.6%
|
3,13
|
133 170 USD
|
|
|
2011-09-22 |
2011-09-21 |
VP
Vente planifiée
|
REID CLIFFORD A
Chief Executive Officer
Administrateur exécutif
|
8 000
-100.0%
6,81
54 441 USD
|
8 000
-100.0%
|
6,81
|
54 441 USD
|
|
|
2011-09-22 |
2011-09-20 |
VP
Vente planifiée
|
REID CLIFFORD A
Chief Executive Officer
Administrateur exécutif
|
8 000
-100.0%
7,30
58 367 USD
|
8 000
-100.0%
|
7,30
|
58 367 USD
|
|
|
2011-08-12 |
2011-08-08 |
A
Achat
|
RAFFEL KEITH
SVP & Chief Commercial Officer
Dirigeant
|
10 000
+inf%
7,94
79 364 USD
|
10 000
+inf%
|
7,94
|
79 364 USD
|
|
|
2011-05-31 |
2011-05-26 |
A
Achat
|
DONDERO JAMES D
Actionnaire important
|
10 623
+0.4%
12,50
132 788 USD
|
10 623
+0.4%
|
12,50
|
132 788 USD
|
|
|
2010-11-16 |
2010-11-16 |
A
Achat
|
ORBIMED ADVISORS LLC
Actionnaire important
|
5 687
+17.0%
9,00
51 183 USD
|
5 687
+17.0%
|
9,00
|
51 183 USD
|
|
|
2010-11-16 |
2010-11-16 |
A
Achat
|
ORBIMED ADVISORS LLC
Actionnaire important
|
597 091
+17.0%
9,00
5 373 819 USD
|
597 091
+17.0%
|
9,00
|
5 373 819 USD
|
|
|
2010-11-16 |
2010-11-16 |
A
Achat
|
Prospect Venture Partners III L P
Actionnaire important
|
333 333
+12.5%
9,00
2 999 997 USD
|
333 333
+12.5%
|
9,00
|
2 999 997 USD
|
|
|
2010-11-16 |
2010-11-16 |
A
Achat
|
ENTERPRISE PARTNERS V L P
Actionnaire important
|
111 111
+20.0%
9,00
999 999 USD
|
111 111
+20.0%
|
9,00
|
999 999 USD
|
|
|
2010-11-16 |
2010-11-16 |
A
Achat
|
BARKAS ALEXANDER E
Administrateur non-exécutif
Actionnaire important
|
333 333
+12.5%
9,00
2 999 997 USD
|
333 333
+12.5%
|
9,00
|
2 999 997 USD
|
|
|
2010-11-16 |
2010-11-16 |
A
Achat
|
SENYEI ANDREW E
Administrateur non-exécutif
Actionnaire important
|
111 111
+20.0%
9,00
999 999 USD
|
111 111
+20.0%
|
9,00
|
999 999 USD
|
|
|
2010-11-16 |
2010-11-16 |
A
Achat
|
ESSEX WOODLANDS HEALTH VENTURES FUND VIII LP
Actionnaire important
|
17 124
+17.0%
9,00
154 116 USD
|
17 124
+17.0%
|
9,00
|
154 116 USD
|
|
|
2010-11-16 |
2010-11-16 |
A
Achat
|
ESSEX WOODLANDS HEALTH VENTURES FUND VIII LP
Actionnaire important
|
39 386
+17.0%
9,00
354 474 USD
|
39 386
+17.0%
|
9,00
|
354 474 USD
|
|
|
2010-11-16 |
2010-11-16 |
A
Achat
|
ESSEX WOODLANDS HEALTH VENTURES FUND VIII LP
Actionnaire important
|
546 268
+17.0%
9,00
4 916 412 USD
|
546 268
+17.0%
|
9,00
|
4 916 412 USD
|
|
