|
2015-03-17 |
2015-03-16 |
VP
Vente planifiée
|
Stamler David A
Chief Medical Officer
Dirigeant
|
2 600
-72.6%
80,08
208 195 USD
|
2 600
-72.6%
|
80,08
|
208 195 USD
|
|
|
2015-03-17 |
2015-03-16 |
VP
Vente planifiée
|
Stamler David A
Chief Medical Officer
Dirigeant
|
400
-10.0%
79,55
31 820 USD
|
400
-10.0%
|
79,55
|
31 820 USD
|
|
|
2015-02-17 |
2015-02-13 |
V
Vente
|
CMEA Ventures VII LP
Actionnaire important
|
1 047
-1.4%
62,98
65 943 USD
|
1 047
-1.4%
|
62,98
|
65 943 USD
|
|
|
2015-02-17 |
2015-02-13 |
V
Vente
|
CMEA Ventures VII LP
Actionnaire important
|
40 786
-1.4%
62,98
2 568 825 USD
|
40 786
-1.4%
|
62,98
|
2 568 825 USD
|
|
|
2015-02-17 |
2015-02-12 |
V
Vente
|
CMEA Ventures VII LP
Actionnaire important
|
325
-0.4%
64,00
20 800 USD
|
325
-0.4%
|
64,00
|
20 800 USD
|
|
|
2015-02-17 |
2015-02-12 |
V
Vente
|
CMEA Ventures VII LP
Actionnaire important
|
1 696
-2.1%
62,96
106 782 USD
|
1 696
-2.1%
|
62,96
|
106 782 USD
|
|
|
2015-02-17 |
2015-02-12 |
V
Vente
|
CMEA Ventures VII LP
Actionnaire important
|
12 675
-0.4%
64,00
811 200 USD
|
12 675
-0.4%
|
64,00
|
811 200 USD
|
|
|
2015-02-17 |
2015-02-12 |
V
Vente
|
CMEA Ventures VII LP
Actionnaire important
|
66 138
-2.1%
62,96
4 164 128 USD
|
66 138
-2.1%
|
62,96
|
4 164 128 USD
|
|
|
2015-02-11 |
2015-02-11 |
V
Vente
|
CMEA Ventures VII LP
Actionnaire important
|
1 327
-1.6%
61,84
82 062 USD
|
1 327
-1.6%
|
61,84
|
82 062 USD
|
|
|
2015-02-11 |
2015-02-11 |
V
Vente
|
CMEA Ventures VII LP
Actionnaire important
|
51 773
-1.6%
61,84
3 201 642 USD
|
51 773
-1.6%
|
61,84
|
3 201 642 USD
|
|
|
2015-02-11 |
2015-02-10 |
V
Vente
|
CMEA Ventures VII LP
Actionnaire important
|
530
-0.7%
60,05
31 827 USD
|
530
-0.7%
|
60,05
|
31 827 USD
|
|
|
2015-02-11 |
2015-02-10 |
V
Vente
|
CMEA Ventures VII LP
Actionnaire important
|
20 670
-0.6%
60,05
1 241 234 USD
|
20 670
-0.6%
|
60,05
|
1 241 234 USD
|
|
|
2015-02-11 |
2015-02-09 |
V
Vente
|
CMEA Ventures VII LP
Actionnaire important
|
246
-0.3%
59,00
14 514 USD
|
246
-0.3%
|
59,00
|
14 514 USD
|
|
|
2015-02-11 |
2015-02-09 |
V
Vente
|
CMEA Ventures VII LP
Actionnaire important
|
9 608
-0.3%
59,00
566 872 USD
|
9 608
-0.3%
|
59,00
|
566 872 USD
|
|
|
2015-02-06 |
2015-02-06 |
V
Vente
|
CMEA Ventures VII LP
Actionnaire important
|
757
-0.9%
59,48
45 026 USD
|
757
-0.9%
|
59,48
|
45 026 USD
|
|
|
2015-02-06 |
2015-02-06 |
V
Vente
|
CMEA Ventures VII LP
Actionnaire important
|
29 522
-0.9%
59,48
1 755 969 USD
|
29 522
-0.9%
|
59,48
|
1 755 969 USD
|
|
|
2015-02-06 |
2015-02-05 |
V
Vente
|
CMEA Ventures VII LP
Actionnaire important
|
322
-0.4%
59,51
19 162 USD
|
322
-0.4%
|
59,51
|
19 162 USD
|
|
|
2015-02-06 |
2015-02-05 |
V
Vente
|
CMEA Ventures VII LP
Actionnaire important
|
12 578
-0.4%
59,51
748 517 USD
|
12 578
-0.4%
|
59,51
|
748 517 USD
|
|
|
2015-02-06 |
2015-02-04 |
V
Vente
|
CMEA Ventures VII LP
Actionnaire important
|
1 250
-1.5%
59,30
74 125 USD
|
1 250
-1.5%
|
59,30
|
74 125 USD
|
|
|
2015-02-06 |
2015-02-04 |
V
Vente
|
CMEA Ventures VII LP
Actionnaire important
|
48 750
-1.5%
59,30
2 890 875 USD
|
48 750
-1.5%
|
59,30
|
2 890 875 USD
|
|
|
2015-01-30 |
2015-01-28 |
V
Vente
|
Thomas, McNerney & Partners II, LLC
Administrateur non-exécutif
Actionnaire important
|
730 000
-13.1%
53,11
38 770 300 USD
|
730 000
-13.1%
|
53,11
|
38 770 300 USD
|
|
|
2015-01-30 |
2015-01-28 |
V
Vente
|
Zisson Alex
Administrateur non-exécutif
|
730 000
-13.1%
53,11
38 770 300 USD
|
730 000
-13.1%
|
53,11
|
38 770 300 USD
|
|
|
2015-01-28 |
2015-01-28 |
A
Achat
|
Flynn James E
Actionnaire important
|
192 240
+24.6%
56,50
10 861 560 USD
|
192 240
+24.6%
|
56,50
|
10 861 560 USD
|
|
|
2015-01-28 |
2015-01-28 |
A
Achat
|
Flynn James E
Actionnaire important
|
167 760
+24.6%
56,50
9 478 440 USD
|
167 760
+24.6%
|
56,50
|
9 478 440 USD
|
|
|
2015-01-28 |
2015-01-28 |
A
Achat
|
Flynn James E
Actionnaire important
|
566 825
+92.0%
56,50
32 025 613 USD
|
566 825
+92.0%
|
56,50
|
32 025 613 USD
|
|
|
2015-01-28 |
2015-01-28 |
A
Achat
|
Flynn James E
Actionnaire important
|
458 175
+92.5%
56,50
25 886 888 USD
|
458 175
+92.5%
|
56,50
|
25 886 888 USD
|
|
|
2015-01-28 |
2015-01-28 |
V
Vente
|
FERGUSON RODNEY A
Administrateur non-exécutif
Actionnaire important
|
270 000
-9.7%
53,11
14 339 700 USD
|
270 000
-9.7%
|
53,11
|
14 339 700 USD
|
|
|
2015-01-28 |
2015-01-28 |
V
Vente
|
Panorama Capital, L.P.
Actionnaire important
|
270 000
-9.7%
53,11
14 339 700 USD
|
270 000
-9.7%
|
53,11
|
14 339 700 USD
|
|
|
2015-01-28 |
2015-01-28 |
A
Achat
|
Flynn James E
Actionnaire important
|
115 000
+30.7%
56,50
6 497 500 USD
|
115 000
+30.7%
|
56,50
|
6 497 500 USD
|
|
|
2015-02-17 |
2015-01-08 |
V
Vente
|
CMEA Ventures VII LP
Actionnaire important
|
84
-0.1%
49,13
4 127 USD
|
84
-0.1%
|
49,13
|
4 127 USD
|
|
|
2015-02-17 |
2015-01-08 |
V
Vente
|
CMEA Ventures VII LP
Actionnaire important
|
3 260
-0.1%
49,13
160 161 USD
|
3 260
-0.1%
|
49,13
|
160 161 USD
|
|
|
2014-12-23 |
2014-12-22 |
VP
Vente planifiée
|
Stamler David A
Chief Medical Officer
Dirigeant
|
1 100
-52.8%
53,92
59 316 USD
|
1 100
-52.8%
|
53,92
|
59 316 USD
|
|
|
2014-12-23 |
2014-12-22 |
VP
Vente planifiée
|
Stamler David A
Chief Medical Officer
Dirigeant
|
1 560
-42.8%
53,28
83 118 USD
|
1 560
-42.8%
|
53,28
|
83 118 USD
|
|
|
2014-12-22 |
2014-12-18 |
V
Vente
|
CMEA Ventures VII LP
Actionnaire important
|
4 875
-5.1%
50,14
244 433 USD
|
4 875
-5.1%
|
50,14
|
244 433 USD
|
|
|
2014-12-22 |
2014-12-18 |
V
Vente
|
CMEA Ventures VII LP
Actionnaire important
|
190 125
-5.1%
50,14
9 532 868 USD
|
190 125
-5.1%
|
50,14
|
9 532 868 USD
|
|
|
2014-10-31 |
2014-10-30 |
V
Vente
|
CMEA Ventures VII LP
Actionnaire important
|
197
-0.2%
27,33
5 383 USD
|
197
-0.2%
|
27,33
|
5 383 USD
|
|
|
2014-10-31 |
2014-10-30 |
V
Vente
|
CMEA Ventures VII LP
Actionnaire important
|
7 633
-0.2%
27,33
208 582 USD
|
7 633
-0.2%
|
27,33
|
208 582 USD
|
|
|
2014-10-31 |
2014-10-29 |
V
Vente
|
CMEA Ventures VII LP
Actionnaire important
|
279
-0.3%
27,02
7 539 USD
|
279
-0.3%
|
27,02
|
7 539 USD
|
|
|
2014-10-31 |
2014-10-29 |
V
Vente
|
CMEA Ventures VII LP
Actionnaire important
|
10 891
-0.3%
27,02
294 307 USD
|
10 891
-0.3%
|
27,02
|
294 307 USD
|
|
|
2014-10-29 |
2014-10-28 |
V
Vente
|
CMEA Ventures VII LP
Actionnaire important
|
275
-0.3%
26,99
7 422 USD
|
275
-0.3%
|
26,99
|
7 422 USD
|
|
|
2014-10-29 |
2014-10-28 |
V
Vente
|
CMEA Ventures VII LP
Actionnaire important
|
10 725
-0.3%
26,99
289 476 USD
|
10 725
-0.3%
|
26,99
|
289 476 USD
|
|
|
2014-10-29 |
2014-10-27 |
V
Vente
|
CMEA Ventures VII LP
Actionnaire important
|
87
-0.1%
27,11
2 359 USD
|
87
-0.1%
|
27,11
|
2 359 USD
|
|
|
2014-10-29 |
2014-10-27 |
V
Vente
|
CMEA Ventures VII LP
Actionnaire important
|
3 413
-0.1%
27,11
92 541 USD
|
3 413
-0.1%
|
27,11
|
92 541 USD
|
|
|
2014-10-27 |
2014-10-24 |
V
Vente
|
CMEA Ventures VII LP
Actionnaire important
|
272
-0.3%
27,09
7 367 USD
|
272
-0.3%
|
27,09
|
7 367 USD
|
|
|
2014-10-27 |
2014-10-24 |
V
Vente
|
CMEA Ventures VII LP
Actionnaire important
|
10 628
-0.3%
27,09
287 866 USD
|
10 628
-0.3%
|
27,09
|
287 866 USD
|
|
|
2014-10-27 |
2014-10-23 |
V
Vente
|
CMEA Ventures VII LP
Actionnaire important
|
140
-0.1%
26,74
3 743 USD
|
140
-0.1%
|
26,74
|
3 743 USD
|
|
|
2014-10-27 |
2014-10-23 |
V
Vente
|
CMEA Ventures VII LP
Actionnaire important
|
5 460
-0.1%
26,74
145 974 USD
|
5 460
-0.1%
|
26,74
|
145 974 USD
|
|
|
2014-10-08 |
2014-10-06 |
V
Vente
|
CMEA Ventures VII LP
Actionnaire important
|
178
-0.2%
23,45
4 173 USD
|
178
-0.2%
|
23,45
|
4 173 USD
|
|
|
2014-10-08 |
2014-10-06 |
V
Vente
|
CMEA Ventures VII LP
Actionnaire important
|
6 931
-0.2%
23,45
162 497 USD
|
6 931
-0.2%
|
23,45
|
162 497 USD
|
|
|
2014-09-22 |
2014-09-19 |
A
Achat
|
PROEHL GERALD T
Administrateur non-exécutif
|
1 466
+inf%
21,75
31 885 USD
|
1 466
+inf%
|
21,75
|
31 885 USD
|
|
|
2014-09-08 |
2014-09-05 |
V
Vente
|
CMEA Ventures VII LP
Actionnaire important
|
222
-0.2%
23,50
5 217 USD
|
222
-0.2%
|
23,50
|
5 217 USD
|
|
|
2014-09-08 |
2014-09-05 |
V
Vente
|
CMEA Ventures VII LP
Actionnaire important
|
8 678
-0.2%
23,50
203 926 USD
|
8 678
-0.2%
|
23,50
|
203 926 USD
|
|
|
2014-09-08 |
2014-09-04 |
V
Vente
|
CMEA Ventures VII LP
Actionnaire important
|
417
-0.4%
24,05
10 030 USD
|
417
-0.4%
|
24,05
|
10 030 USD
|
|
|
2014-09-08 |
2014-09-04 |
V
Vente
|
CMEA Ventures VII LP
Actionnaire important
|
16 283
-0.4%
24,05
391 634 USD
|
16 283
-0.4%
|
24,05
|
391 634 USD
|
|
|
2014-09-04 |
2014-09-03 |
V
Vente
|
CMEA Ventures VII LP
Actionnaire important
|
312
-0.3%
23,09
7 205 USD
|
312
-0.3%
|
23,09
|
7 205 USD
|
|
|
2014-09-04 |
2014-09-03 |
V
Vente
|
CMEA Ventures VII LP
Actionnaire important
|
12 188
-0.3%
23,09
281 467 USD
|
12 188
-0.3%
|
23,09
|
281 467 USD
|
|
|
2014-09-04 |
2014-09-02 |
V
Vente
|
CMEA Ventures VII LP
Actionnaire important
|
255
-0.3%
23,07
5 883 USD
|
255
-0.3%
|
23,07
|
5 883 USD
|
|
|
2014-09-04 |
2014-09-02 |
V
Vente
|
CMEA Ventures VII LP
Actionnaire important
|
9 945
-0.3%
23,07
229 425 USD
|
9 945
-0.3%
|
23,07
|
229 425 USD
|
|
|
2014-09-03 |
2014-08-29 |
V
Vente
|
CMEA Ventures VII LP
Actionnaire important
|
217
-0.2%
22,59
4 903 USD
|
217
-0.2%
|
22,59
|
4 903 USD
|
|
|
2014-09-03 |
2014-08-29 |
V
Vente
|
CMEA Ventures VII LP
Actionnaire important
|
8 483
-0.2%
22,59
191 650 USD
|
8 483
-0.2%
|
22,59
|
191 650 USD
|
|
|
2014-08-29 |
2014-08-28 |
V
Vente
|
CMEA Ventures VII LP
Actionnaire important
|
305
-0.3%
22,24
6 784 USD
|
305
-0.3%
|
22,24
|
6 784 USD
|
|
|
2014-08-29 |
2014-08-28 |
V
Vente
|
CMEA Ventures VII LP
Actionnaire important
|
11 895
-0.3%
22,24
264 564 USD
|
11 895
-0.3%
|
22,24
|
264 564 USD
|
|
|
2014-08-29 |
2014-08-27 |
V
Vente
|
CMEA Ventures VII LP
Actionnaire important
|
435
-0.5%
21,88
9 517 USD
|
435
-0.5%
|
21,88
|
9 517 USD
|
|
|
2014-08-29 |
2014-08-27 |
V
Vente
|
CMEA Ventures VII LP
Actionnaire important
|
16 965
-0.5%
21,88
371 148 USD
|
16 965
-0.5%
|
21,88
|
371 148 USD
|
|
|
2014-08-28 |
2014-08-26 |
V
Vente
|
CMEA Ventures VII LP
Actionnaire important
|
157
-0.2%
21,35
3 352 USD
|
157
-0.2%
|
21,35
|
3 352 USD
|
|
|
2014-08-28 |
2014-08-26 |
V
Vente
|
CMEA Ventures VII LP
Actionnaire important
|
6 143
-0.2%
21,35
131 165 USD
|
6 143
-0.2%
|
21,35
|
131 165 USD
|
|
|
2014-08-27 |
2014-08-25 |
V
Vente
|
CMEA Ventures VII LP
Actionnaire important
|
135
-0.1%
20,81
2 809 USD
|
135
-0.1%
|
20,81
|
2 809 USD
|
|
|
2014-08-27 |
2014-08-25 |
V
Vente
|
CMEA Ventures VII LP
Actionnaire important
|
5 265
-0.1%
20,81
109 549 USD
|
5 265
-0.1%
|
20,81
|
109 549 USD
|
|
|
2014-08-26 |
2014-08-22 |
V
Vente
|
CMEA Ventures VII LP
Actionnaire important
|
42
-0.0%
20,56
863 USD
|
42
-0.0%
|
20,56
|
863 USD
|
|
|
2014-08-26 |
2014-08-22 |
V
Vente
|
CMEA Ventures VII LP
Actionnaire important
|
1 658
-0.0%
20,56
34 085 USD
|
1 658
-0.0%
|
20,56
|
34 085 USD
|
|
|
2014-07-16 |
2014-07-16 |
A
Achat
|
GREER R SCOTT
Administrateur non-exécutif
|
5 190
+259.5%
19,25
99 908 USD
|
5 190
+259.5%
|
19,25
|
99 908 USD
|
|
|
2014-09-09 |
2014-05-14 |
V
Vente
|
Thomas, McNerney & Partners II L.P.
Actionnaire important
|
12 400
-0.2%
20,60
255 415 USD
|
12 400
-0.2%
|
20,60
|
255 415 USD
|
|
|
2014-09-09 |
2014-05-14 |
V
Vente
|
Zisson Alex
Administrateur non-exécutif
Actionnaire important
|
12 400
-0.2%
20,60
255 415 USD
|
12 400
-0.2%
|
20,60
|
255 415 USD
|
|
|
2014-10-01 |
2014-02-10 |
A
Achat
|
Thomas, McNerney & Partners II, LLC
Administrateur non-exécutif
Actionnaire important
|
82 475
+1.6%
12,00
989 700 USD
|
82 475
+1.6%
|
12,00
|
989 700 USD
|
|
|
2014-02-12 |
2014-02-10 |
A
Achat
|
CMEA Ventures VII LP
Actionnaire important
|
2 688
+2.9%
12,00
32 256 USD
|
2 688
+2.9%
|
12,00
|
32 256 USD
|
|
