|
2020-10-05 |
2020-10-01 |
V
Vente
|
Camber Capital Management LP
Actionnaire important
|
4 390 000
-100.0%
13,57
59 586 787 USD
|
4 390 000
-100.0%
|
13,57
|
59 586 787 USD
|
|
|
2020-03-18 |
2020-03-16 |
A
Achat
|
ARMISTICE CAPITAL, LLC
Actionnaire important
|
24 000
+7.4%
4,87
116 880 USD
|
24 000
+7.4%
|
4,87
|
116 880 USD
|
|
|
2020-02-27 |
2020-02-25 |
A
Achat
|
ARMISTICE CAPITAL, LLC
Actionnaire important
|
12 000
+3.8%
8,29
99 480 USD
|
12 000
+3.8%
|
8,29
|
99 480 USD
|
|
|
2020-02-27 |
2020-02-25 |
A
Achat
|
ARMISTICE CAPITAL, LLC
Actionnaire important
|
24 000
+8.3%
8,29
198 960 USD
|
24 000
+8.3%
|
8,29
|
198 960 USD
|
|
|
2020-01-28 |
2020-01-27 |
A
Achat
|
ARMISTICE CAPITAL, LLC
Actionnaire important
|
8 000
+2.9%
9,41
75 280 USD
|
8 000
+2.9%
|
9,41
|
75 280 USD
|
|
|
2020-01-28 |
2020-01-27 |
A
Achat
|
ARMISTICE CAPITAL, LLC
Actionnaire important
|
0
0,00
0 USD
|
0
|
0,00
|
0 USD
|
|
|
2020-01-28 |
2020-01-27 |
A
Achat
|
ARMISTICE CAPITAL, LLC
Actionnaire important
|
8 000
+0.2%
9,43
75 440 USD
|
8 000
+0.2%
|
9,43
|
75 440 USD
|
|
|
2020-01-28 |
2020-01-24 |
A
Achat
|
ARMISTICE CAPITAL, LLC
Actionnaire important
|
40 000
+16.7%
9,72
388 800 USD
|
40 000
+16.7%
|
9,72
|
388 800 USD
|
|
|
2020-01-28 |
2020-01-24 |
A
Achat
|
ARMISTICE CAPITAL, LLC
Actionnaire important
|
0
0,00
0 USD
|
0
|
0,00
|
0 USD
|
|
|
2020-01-28 |
2020-01-24 |
A
Achat
|
ARMISTICE CAPITAL, LLC
Actionnaire important
|
34 000
+0.8%
9,58
325 720 USD
|
34 000
+0.8%
|
9,58
|
325 720 USD
|
|
|
2020-01-13 |
2020-01-10 |
A
Achat
|
ARMISTICE CAPITAL, LLC
Actionnaire important
|
0
0,00
0 USD
|
0
|
0,00
|
0 USD
|
|
|
2020-01-13 |
2020-01-10 |
A
Achat
|
ARMISTICE CAPITAL, LLC
Actionnaire important
|
18 000
+0.4%
11,64
209 520 USD
|
18 000
+0.4%
|
11,64
|
209 520 USD
|
|
|
2020-01-13 |
2020-01-09 |
A
Achat
|
ARMISTICE CAPITAL, LLC
Actionnaire important
|
0
0,00
0 USD
|
0
|
0,00
|
0 USD
|
|
|
2020-01-13 |
2020-01-09 |
A
Achat
|
ARMISTICE CAPITAL, LLC
Actionnaire important
|
12 466
+0.3%
12,33
153 706 USD
|
12 466
+0.3%
|
12,33
|
153 706 USD
|
|
|
2020-01-13 |
2020-01-09 |
V
Vente
|
ARMISTICE CAPITAL, LLC
Actionnaire important
|
0
0,00
0 USD
|
0
|
0,00
|
0 USD
|
|
|
2020-01-13 |
2020-01-09 |
V
Vente
|
ARMISTICE CAPITAL, LLC
Actionnaire important
|
12 466
-0.3%
12,43
154 952 USD
|
12 466
-0.3%
|
12,43
|
154 952 USD
|
|
|
2019-08-09 |
2019-08-09 |
A
Achat
|
Camber Capital Management LP
|
3 400
+0.1%
9,18
31 206 USD
|
3 400
+0.1%
|
9,18
|
31 206 USD
|
|
|
2019-08-09 |
2019-08-09 |
A
Achat
|
Camber Capital Management LP
|
26 600
+0.6%
8,94
237 791 USD
|
26 600
+0.6%
|
8,94
|
237 791 USD
|
|
|
2019-08-09 |
2019-08-07 |
A
Achat
|
ARMISTICE CAPITAL, LLC
Actionnaire important
|
40 000
+20.0%
7,43
297 200 USD
|
40 000
+20.0%
|
7,43
|
297 200 USD
|
|
|
2019-08-09 |
2019-08-07 |
A
Achat
|
ARMISTICE CAPITAL, LLC
Actionnaire important
|
0
0,00
0 USD
|
0
|
0,00
|
0 USD
|
|
|
2019-08-09 |
2019-08-07 |
A
Achat
|
ARMISTICE CAPITAL, LLC
Actionnaire important
|
260 000
+6.8%
7,32
1 903 200 USD
|
260 000
+6.8%
|
7,32
|
1 903 200 USD
|
|
|
2019-08-09 |
2019-08-07 |
A
Achat
|
Camber Capital Management LP
|
4 000
+0.1%
7,58
30 300 USD
|
4 000
+0.1%
|
7,58
|
30 300 USD
|
|
|
2019-08-09 |
2019-08-07 |
A
Achat
|
Camber Capital Management LP
|
50 000
+1.2%
7,74
387 000 USD
|
50 000
+1.2%
|
7,74
|
387 000 USD
|
|
|
2019-08-09 |
2019-08-07 |
A
Achat
|
Camber Capital Management LP
|
301 000
+7.5%
7,79
2 343 496 USD
|
301 000
+7.5%
|
7,79
|
2 343 496 USD
|
|
|
2019-06-27 |
2019-06-27 |
A
Achat
|
ARMISTICE CAPITAL, LLC
Actionnaire important
|
20 000
+11.1%
9,47
189 400 USD
|
20 000
+11.1%
|
9,47
|
189 400 USD
|
|
|
2019-06-27 |
2019-06-27 |
A
Achat
|
ARMISTICE CAPITAL, LLC
Actionnaire important
|
0
0,00
0 USD
|
0
|
0,00
|
0 USD
|
|
|
2019-06-27 |
2019-06-27 |
A
Achat
|
ARMISTICE CAPITAL, LLC
Actionnaire important
|
44 000
+1.2%
9,52
418 880 USD
|
44 000
+1.2%
|
9,52
|
418 880 USD
|
|
|
2019-06-27 |
2019-06-26 |
A
Achat
|
ARMISTICE CAPITAL, LLC
Actionnaire important
|
0
0,00
0 USD
|
0
|
0,00
|
0 USD
|
|
|
2019-06-27 |
2019-06-26 |
A
Achat
|
ARMISTICE CAPITAL, LLC
Actionnaire important
|
120 000
+3.3%
9,13
1 095 600 USD
|
120 000
+3.3%
|
9,13
|
1 095 600 USD
|
|
|
2019-06-27 |
2019-06-25 |
A
Achat
|
ARMISTICE CAPITAL, LLC
Actionnaire important
|
30 000
+20.0%
8,86
265 800 USD
|
30 000
+20.0%
|
8,86
|
265 800 USD
|
|
|
2019-06-27 |
2019-06-25 |
A
Achat
|
ARMISTICE CAPITAL, LLC
Actionnaire important
|
25 000
+20.0%
8,85
221 250 USD
|
25 000
+20.0%
|
8,85
|
221 250 USD
|
|
|
2019-06-27 |
2019-06-25 |
A
Achat
|
ARMISTICE CAPITAL, LLC
Actionnaire important
|
0
0,00
0 USD
|
0
|
0,00
|
0 USD
|
|
|
2019-06-27 |
2019-06-25 |
A
Achat
|
ARMISTICE CAPITAL, LLC
Actionnaire important
|
259 016
+7.7%
8,59
2 224 947 USD
|
259 016
+7.7%
|
8,59
|
2 224 947 USD
|
|
|
2019-05-29 |
2019-05-28 |
A
Achat
|
Krop Julie
Chief Medical Officer
|
10 000
+14.0%
9,91
99 100 USD
|
10 000
+14.0%
|
9,91
|
99 100 USD
|
|
|
2019-05-09 |
2019-05-09 |
A
Achat
|
Bolgiano Elizabeth Scott
Chief Human Resources Officer
|
5 000
+7.2%
10,93
54 650 USD
|
5 000
+7.2%
|
10,93
|
54 650 USD
|
|
|
2019-05-09 |
2019-05-09 |
A
Achat
|
HEIDEN WILLIAM K
President & CEO
Administrateur exécutif
|
10 000
+2.1%
10,70
107 000 USD
|
10 000
+2.1%
|
10,70
|
107 000 USD
|
|
|
2019-03-11 |
2019-03-07 |
VP
Vente planifiée
|
Vittiglio Joseph
EVP, General Counsel
|
1 425
-1.8%
14,01
19 964 USD
|
1 425
-1.8%
|
14,01
|
19 964 USD
|
|
|
2018-08-08 |
2018-08-07 |
VP
Vente planifiée
|
HEIDEN WILLIAM K
President & CEO
Administrateur exécutif
|
5 000
-1.5%
25,00
125 000 USD
|
5 000
-1.5%
|
25,00
|
125 000 USD
|
|
|
2018-06-05 |
2018-06-04 |
VP
Vente planifiée
|
HEIDEN WILLIAM K
President & CEO
Administrateur exécutif
|
20 000
-5.7%
25,00
500 000 USD
|
20 000
-5.7%
|
25,00
|
500 000 USD
|
|
|
2018-03-06 |
2018-03-06 |
VP
Vente planifiée
|
Vittiglio Joseph
EVP, General Counsel
|
770
-1.4%
20,80
16 016 USD
|
770
-1.4%
|
20,80
|
16 016 USD
|
|
|
2017-08-30 |
2017-08-29 |
VP
Vente planifiée
|
Vittiglio Joseph
SVP, General Counsel
|
1 250
-3.6%
16,75
20 938 USD
|
1 250
-3.6%
|
16,75
|
20 938 USD
|
|
|
2017-07-14 |
2017-07-13 |
VP
Vente planifiée
|
Krop Julie
SVP Clinical & Regulatory, CMO
Dirigeant
|
4 938
-14.8%
20,00
98 760 USD
|
4 938
-14.8%
|
20,00
|
98 760 USD
|
|
|
2017-05-02 |
2017-05-01 |
VP
Vente planifiée
|
Krop Julie
SVP Clinical & Regulatory, CMO
Dirigeant
|
1 891
-4.9%
24,45
46 235 USD
|
1 891
-4.9%
|
24,45
|
46 235 USD
|
|
|
2016-10-20 |
2016-10-20 |
VP
Vente planifiée
|
Krop Julie
SVP Clinical & Regulatory, CMO
Dirigeant
|
4 938
-17.3%
24,80
122 462 USD
|
4 938
-17.3%
|
24,80
|
122 462 USD
|
|
|
2015-11-10 |
2015-11-10 |
A
Achat
|
Fallon John A.
Administrateur non-exécutif
|
3 230
+113.1%
31,20
100 776 USD
|
3 230
+113.1%
|
31,20
|
100 776 USD
|
|
|
2015-08-07 |
2015-08-05 |
VP
Vente planifiée
|
THOMAS FRANK E
President & COO
Dirigeant
|
15 000
-12.1%
66,85
1 002 750 USD
|
15 000
-12.1%
|
66,85
|
1 002 750 USD
|
|
|
2015-07-17 |
2015-07-15 |
VP
Vente planifiée
|
HEIDEN WILLIAM K
CEO
Administrateur exécutif
|
20 000
-8.8%
75,00
1 500 000 USD
|
20 000
-8.8%
|
75,00
|
1 500 000 USD
|
|
|
2015-06-17 |
2015-06-15 |
VP
Vente planifiée
|
Holmes Scott A
SVP, Finance and Treasurer
Dirigeant
|
6 234
-10.7%
66,63
415 371 USD
|
6 234
-10.7%
|
66,63
|
415 371 USD
|
|
|
2015-06-08 |
2015-06-05 |
VP
Vente planifiée
|
HEIDEN WILLIAM K
CEO
Administrateur exécutif
|
12 128
-5.5%
71,52
867 395 USD
|
12 128
-5.5%
|
71,52
|
867 395 USD
|
|
|
2015-06-08 |
2015-06-05 |
VP
Vente planifiée
|
HEIDEN WILLIAM K
CEO
Administrateur exécutif
|
4 680
-2.1%
70,69
330 829 USD
|
4 680
-2.1%
|
70,69
|
330 829 USD
|
|
|
2015-06-08 |
2015-06-05 |
VP
Vente planifiée
|
HEIDEN WILLIAM K
CEO
Administrateur exécutif
|
36 550
-13.9%
69,77
2 550 094 USD
|
36 550
-13.9%
|
69,77
|
2 550 094 USD
|
|
|
2015-06-08 |
2015-06-05 |
VP
Vente planifiée
|
HEIDEN WILLIAM K
CEO
Administrateur exécutif
|
6 642
-2.5%
68,90
457 634 USD
|
6 642
-2.5%
|
68,90
|
457 634 USD
|
|
|
2015-06-08 |
2015-06-04 |
V
Vente
|
THOMAS FRANK E
President & COO
Dirigeant
|
7 996
-6.8%
69,76
557 801 USD
|
7 996
-6.8%
|
69,76
|
557 801 USD
|
|
|
2015-06-08 |
2015-06-04 |
V
Vente
|
THOMAS FRANK E
President & COO
Dirigeant
|
12 004
-9.3%
69,27
831 517 USD
|
12 004
-9.3%
|
69,27
|
831 517 USD
|
|
|
2015-06-05 |
2015-06-03 |
V
Vente
|
Wilson Kenneth H
SVP, Sales and Marketing
Dirigeant
|
5 388
-17.7%
68,77
370 533 USD
|
5 388
-17.7%
|
68,77
|
370 533 USD
|
|
|
2015-06-05 |
2015-06-03 |
V
Vente
|
Holmes Scott A
SVP, Finance and Treasurer
Dirigeant
|
22 516
-42.2%
68,88
1 550 902 USD
|
22 516
-42.2%
|
68,88
|
1 550 902 USD
|
|
|
2015-01-09 |
2015-01-09 |
V
Vente
|
ADAGE CAPITAL PARTNERS GP LLC
Actionnaire important
|
17 493
-0.7%
43,48
760 596 USD
|
17 493
-0.7%
|
43,48
|
760 596 USD
|
|
|
2015-01-09 |
2015-01-08 |
V
Vente
|
ADAGE CAPITAL PARTNERS GP LLC
Actionnaire important
|
25 169
-1.0%
46,00
1 157 774 USD
|
25 169
-1.0%
|
46,00
|
1 157 774 USD
|
|
|
2015-01-09 |
2015-01-08 |
V
Vente
|
ADAGE CAPITAL PARTNERS GP LLC
Actionnaire important
|
10 000
-0.4%
46,25
462 500 USD
|
10 000
-0.4%
|
46,25
|
462 500 USD
|
|
|
2015-01-09 |
2015-01-08 |
V
Vente
|
ADAGE CAPITAL PARTNERS GP LLC
Actionnaire important
|
55 000
-2.1%
45,90
2 524 500 USD
|
55 000
-2.1%
|
45,90
|
2 524 500 USD
|
|
|
2015-01-09 |
2015-01-08 |
V
Vente
|
ADAGE CAPITAL PARTNERS GP LLC
Actionnaire important
|
52 338
-1.9%
46,11
2 413 305 USD
|
52 338
-1.9%
|
46,11
|
2 413 305 USD
|
|
|
2015-01-09 |
2015-01-07 |
V
Vente
|
ADAGE CAPITAL PARTNERS GP LLC
Actionnaire important
|
1 090 000
-28.7%
46,60
50 794 000 USD
|
1 090 000
-28.7%
|
46,60
|
50 794 000 USD
|
|
|
2014-02-26 |
2014-02-26 |
VP
Vente planifiée
|
White Christopher G
Chief Business Officer
Dirigeant
|
400
-1.6%
21,58
8 632 USD
|
400
-1.6%
|
21,58
|
8 632 USD
|
|
|
2014-01-09 |
2014-01-09 |
VP
Vente planifiée
|
White Christopher G
Chief Business Officer
Dirigeant
|
200
-0.8%
22,41
4 482 USD
|
200
-0.8%
|
22,41
|
4 482 USD
|
|
|
2014-01-09 |
2014-01-09 |
VP
Vente planifiée
|
White Christopher G
Chief Business Officer
Dirigeant
|
100
-0.4%
21,40
2 140 USD
|
100
-0.4%
|
21,40
|
2 140 USD
|
|
|
2014-01-09 |
2014-01-09 |
VP
Vente planifiée
|
White Christopher G
Chief Business Officer
Dirigeant
|
1 700
-6.3%
20,61
35 037 USD
|
1 700
-6.3%
|
20,61
|
35 037 USD
|
|
|
2014-01-07 |
2014-01-07 |
VP
Vente planifiée
|
White Christopher G
Chief Business Officer
Dirigeant
|
2 500
-8.0%
24,10
60 250 USD
|
2 500
-8.0%
|
24,10
|
60 250 USD
|
|
|
2013-02-26 |
2013-02-26 |
VP
Vente planifiée
|
White Christopher G
Chief Business Officer
Dirigeant
|
400
-100.0%
16,37
6 548 USD
|
400
-100.0%
|
16,37
|
6 548 USD
|
|
|
2013-02-26 |
2013-02-25 |
VP
Vente planifiée
|
White Christopher G
Chief Business Officer
Dirigeant
|
433
-52.0%
16,39
7 097 USD
|
433
-52.0%
|
16,39
|
7 097 USD
|
|
|
2013-01-09 |
2013-01-09 |
VP
Vente planifiée
|
White Christopher G
Chief Business Officer
Dirigeant
|
3 000
-100.0%
15,80
47 407 USD
|
3 000
-100.0%
|
15,80
|
47 407 USD
|
|
|
2013-01-09 |
2013-01-08 |
VP
Vente planifiée
|
White Christopher G
Chief Business Officer
Dirigeant
|
3 000
-50.0%
15,87
47 600 USD
|
3 000
-50.0%
|
15,87
|
47 600 USD
|
|
|
2013-01-07 |
2013-01-04 |
VP
Vente planifiée
|
White Christopher G
Chief Business Officer
Dirigeant
|
4 000
-40.0%
16,03
64 102 USD
|
4 000
-40.0%
|
16,03
|
64 102 USD
|
|
|
2013-01-04 |
2013-01-03 |
VP
Vente planifiée
|
THOMAS FRANK E
EVP, COO
Dirigeant
|
10 000
-31.2%
15,60
155 969 USD
|
10 000
-31.2%
|
15,60
|
155 969 USD
|
|
|
2012-12-06 |
2012-12-05 |
VP
Vente planifiée
|
Holmes Scott A
Chief Accounting Officer
Dirigeant
|
2 500
-100.0%
14,79
36 975 USD
|
2 500
-100.0%
|
14,79
|
36 975 USD
|
|
|
2012-09-13 |
2012-09-12 |
VP
Vente planifiée
|
Holmes Scott A
Chief Accounting Officer
Dirigeant
|
750
-100.0%
15,54
11 655 USD
|
750
-100.0%
|
15,54
|
11 655 USD
|
|
