|
2023-10-31 |
2023-10-18 |
A
Achat
|
Israel Biotech Fund I, L.P.
Actionnaire important
|
658 858
0,00
0 USD
|
658 858
|
0,00
|
0 USD
|
|
|
2023-10-31 |
2023-10-18 |
A
Achat
|
Israel Biotech Fund I, L.P.
Actionnaire important
|
658 858
0,00
0 USD
|
658 858
|
0,00
|
0 USD
|
|
|
2020-03-16 |
2020-03-13 |
V
Vente
|
APPEL RONI
Administrateur non-exécutif
|
2 401
-18.6%
0,55
1 321 USD
|
2 401
-18.6%
|
0,55
|
1 321 USD
|
|
|
2020-03-16 |
2020-03-12 |
V
Vente
|
APPEL RONI
Administrateur non-exécutif
|
200
-1.5%
0,58
116 USD
|
200
-1.5%
|
0,58
|
116 USD
|
|
|
2020-03-16 |
2020-03-11 |
V
Vente
|
APPEL RONI
Administrateur non-exécutif
|
399
-3.0%
0,67
267 USD
|
399
-3.0%
|
0,67
|
267 USD
|
|
|
2019-04-11 |
2019-04-10 |
A
Achat
|
APPEL RONI
|
3 000
+28.6%
3,80
11 391 USD
|
3 000
+28.6%
|
3,80
|
11 391 USD
|
|
|
2018-11-07 |
2018-11-05 |
V
Vente
|
PETIT ROBERT
Chief Scientific Officer
Dirigeant
|
3 963
-1.7%
0,58
2 299 USD
|
3 963
-1.7%
|
0,58
|
2 299 USD
|
|
|
2018-11-05 |
2018-11-02 |
V
Vente
|
PETIT ROBERT
Chief Scientific Officer
Dirigeant
|
8 491
-3.5%
0,56
4 755 USD
|
8 491
-3.5%
|
0,56
|
4 755 USD
|
|
|
2018-09-13 |
2018-09-11 |
A
Achat
|
APPEL RONI
Administrateur non-exécutif
|
33 333
+26.9%
1,20
40 000 USD
|
33 333
+26.9%
|
1,20
|
40 000 USD
|
|
|
2018-04-03 |
2018-04-02 |
V
Vente
|
PETIT ROBERT
Chief Scientific Officer
|
2 193
-1.0%
1,62
3 553 USD
|
2 193
-1.0%
|
1,62
|
3 553 USD
|
|
|
2018-02-02 |
2018-02-02 |
V
Vente
|
LOMBARDO ANTHONY A
Interim CEO
Dirigeant
|
32
-0.0%
2,93
94 USD
|
32
-0.0%
|
2,93
|
94 USD
|
|
|
2018-01-03 |
2018-01-03 |
V
Vente
|
Bonstein Sara
Chief Financial Officer
Dirigeant
|
5 224
-2.3%
3,18
16 612 USD
|
5 224
-2.3%
|
3,18
|
16 612 USD
|
|
|
2017-11-06 |
2017-11-06 |
V
Vente
|
Bonstein Sara
Chief Financial Officer
|
3 862
-1.7%
3,30
12 745 USD
|
3 862
-1.7%
|
3,30
|
12 745 USD
|
|
|
2017-11-06 |
2017-11-06 |
V
Vente
|
PETIT ROBERT
Chief Scientific Officer
|
3 723
-1.7%
3,30
12 286 USD
|
3 723
-1.7%
|
3,30
|
12 286 USD
|
|
|
2017-11-02 |
2017-11-02 |
V
Vente
|
LOMBARDO ANTHONY A
Interim CEO
|
24
-0.0%
3,19
77 USD
|
24
-0.0%
|
3,19
|
77 USD
|
|
|
2017-11-02 |
2017-11-02 |
V
Vente
|
PETIT ROBERT
Chief Scientific Officer
|
12 625
-5.3%
3,19
40 274 USD
|
12 625
-5.3%
|
3,19
|
40 274 USD
|
|
|
2017-11-02 |
2017-11-02 |
V
Vente
|
Bonstein Sara
Chief Financial Officer
|
12 734
-5.2%
3,19
40 621 USD
|
12 734
-5.2%
|
3,19
|
40 621 USD
|
|
|
2017-10-12 |
2017-10-11 |
V
Vente
|
ADAGE CAPITAL PARTNERS GP, L.L.C.
Actionnaire important
|
600 000
-12.8%
4,30
2 580 000 USD
|
600 000
-12.8%
|
4,30
|
2 580 000 USD
|
|
|
2017-09-26 |
2017-09-26 |
V
Vente
|
ADAGE CAPITAL PARTNERS GP, L.L.C.
Actionnaire important
|
300 000
-6.0%
4,00
1 200 000 USD
|
300 000
-6.0%
|
4,00
|
1 200 000 USD
|
|
|
2017-09-26 |
2017-09-25 |
V
Vente
|
ADAGE CAPITAL PARTNERS GP, L.L.C.
Actionnaire important
|
405 323
-7.5%
4,38
1 775 315 USD
|
405 323
-7.5%
|
4,38
|
1 775 315 USD
|
|
|
2017-09-26 |
2017-09-22 |
V
Vente
|
ADAGE CAPITAL PARTNERS GP, L.L.C.
Actionnaire important
|
534 000
-9.0%
4,68
2 499 120 USD
|
534 000
-9.0%
|
4,68
|
2 499 120 USD
|
|
|
2017-04-03 |
2017-03-31 |
V
Vente
|
PETIT ROBERT
Chief Scientific Officer
|
2 454
-2.0%
8,24
20 221 USD
|
2 454
-2.0%
|
8,24
|
20 221 USD
|
|
|
2017-01-03 |
2016-12-30 |
V
Vente
|
Bonstein Sara
Chief Financial Officer
Dirigeant
|
5 520
-4.2%
7,37
40 682 USD
|
5 520
-4.2%
|
7,37
|
40 682 USD
|
|
|
2016-12-21 |
2016-12-20 |
V
Vente
|
MCKEARN THOMAS J
Administrateur non-exécutif
|
12 316
-15.0%
8,08
99 513 USD
|
12 316
-15.0%
|
8,08
|
99 513 USD
|
|
|
2016-11-02 |
2016-11-02 |
V
Vente
|
PETIT ROBERT
Chief Scientific Officer
Dirigeant
|
2 797
-2.3%
8,32
23 271 USD
|
2 797
-2.3%
|
8,32
|
23 271 USD
|
|
|
2016-11-02 |
2016-11-02 |
V
Vente
|
O'Connor Daniel
Chief Executive Officer
Administrateur exécutif
|
8 240
-2.7%
8,32
68 557 USD
|
8 240
-2.7%
|
8,32
|
68 557 USD
|
|
|
2016-10-26 |
2016-10-25 |
V
Vente
|
Mayes, Gregory T.
Chief Business Officer
Administrateur exécutif
|
19 162
-15.7%
8,23
157 703 USD
|
19 162
-15.7%
|
8,23
|
157 703 USD
|
|
|
2016-08-10 |
2016-08-09 |
V
Vente
|
BERMAN RICHARD J
Administrateur non-exécutif
|
15 761
-23.7%
15,67
246 975 USD
|
15 761
-23.7%
|
15,67
|
246 975 USD
|
|
|
2016-08-10 |
2016-08-09 |
V
Vente
|
SIDRANSKY DAVID
Administrateur non-exécutif
|
11 404
-12.4%
14,85
169 349 USD
|
11 404
-12.4%
|
14,85
|
169 349 USD
|
|
|
2016-08-10 |
2016-08-08 |
V
Vente
|
BERMAN RICHARD J
Administrateur non-exécutif
|
18 000
-21.3%
15,21
273 780 USD
|
18 000
-21.3%
|
15,21
|
273 780 USD
|
|
|
2016-08-10 |
2016-08-08 |
V
Vente
|
SIDRANSKY DAVID
Administrateur non-exécutif
|
11 404
-11.1%
15,17
172 999 USD
|
11 404
-11.1%
|
15,17
|
172 999 USD
|
|
|
2016-05-13 |
2016-05-13 |
V
Vente
|
MCKEARN THOMAS J
Administrateur non-exécutif
|
4 100
-4.8%
7,45
30 545 USD
|
4 100
-4.8%
|
7,45
|
30 545 USD
|
|
|
2016-05-02 |
2016-05-02 |
V
Vente
|
PETIT ROBERT
Chief Scientific Officer
Dirigeant
|
2 785
-2.2%
7,51
20 915 USD
|
2 785
-2.2%
|
7,51
|
20 915 USD
|
|
|
2016-05-02 |
2016-05-02 |
V
Vente
|
O'Connor Daniel
Chief Executive Officer
Dirigeant
|
8 237
-2.6%
7,51
61 860 USD
|
8 237
-2.6%
|
7,51
|
61 860 USD
|
|
|
2016-04-01 |
2016-03-31 |
V
Vente
|
PETIT ROBERT
Chief Scientific Officer
Dirigeant
|
3 325
-2.5%
9,13
30 357 USD
|
3 325
-2.5%
|
9,13
|
30 357 USD
|
|
|
2016-03-18 |
2016-03-16 |
V
Vente
|
MCKEARN THOMAS J
Administrateur non-exécutif
|
14 000
-14.0%
8,25
115 500 USD
|
14 000
-14.0%
|
8,25
|
115 500 USD
|
|
|
2016-02-25 |
2016-02-24 |
V
Vente
|
Bonstein Sara
Chief Financial Officer
Dirigeant
|
15 037
-15.8%
5,58
83 906 USD
|
15 037
-15.8%
|
5,58
|
83 906 USD
|
|
|
2016-02-01 |
2016-01-29 |
V
Vente
|
PETIT ROBERT
Chief Scientific Officer
Dirigeant
|
3 099
-2.3%
6,88
21 321 USD
|
3 099
-2.3%
|
6,88
|
21 321 USD
|
|
|
2016-02-01 |
2016-01-29 |
V
Vente
|
O'Connor Daniel
Chief Executive Officer
Dirigeant
|
8 818
-2.7%
6,88
60 668 USD
|
8 818
-2.7%
|
6,88
|
60 668 USD
|
|
|
2015-08-24 |
2015-08-24 |
A
Achat
|
ADAGE CAPITAL PARTNERS GP LLC
Actionnaire important
|
12 100
+0.2%
14,47
175 087 USD
|
12 100
+0.2%
|
14,47
|
175 087 USD
|
|
|
2015-08-24 |
2015-08-24 |
A
Achat
|
ADAGE CAPITAL PARTNERS GP LLC
Actionnaire important
|
9 500
+0.2%
13,73
130 435 USD
|
9 500
+0.2%
|
13,73
|
130 435 USD
|
|
|
2015-08-24 |
2015-08-24 |
A
Achat
|
ADAGE CAPITAL PARTNERS GP LLC
Actionnaire important
|
3 400
+0.1%
14,06
47 804 USD
|
3 400
+0.1%
|
14,06
|
47 804 USD
|
|
|
2015-08-24 |
2015-08-24 |
A
Achat
|
ADAGE CAPITAL PARTNERS GP LLC
Actionnaire important
|
20 000
+0.3%
12,90
258 000 USD
|
20 000
+0.3%
|
12,90
|
258 000 USD
|
|
|
2015-08-24 |
2015-08-24 |
A
Achat
|
ADAGE CAPITAL PARTNERS GP LLC
Actionnaire important
|
5 000
+0.1%
13,87
69 350 USD
|
5 000
+0.1%
|
13,87
|
69 350 USD
|
|
|
2015-08-24 |
2015-08-21 |
A
Achat
|
ADAGE CAPITAL PARTNERS GP LLC
Actionnaire important
|
75 000
+1.3%
14,21
1 065 750 USD
|
75 000
+1.3%
|
14,21
|
1 065 750 USD
|
|
|
2015-08-24 |
2015-08-20 |
A
Achat
|
ADAGE CAPITAL PARTNERS GP LLC
Actionnaire important
|
12 000
+0.2%
14,17
170 040 USD
|
12 000
+0.2%
|
14,17
|
170 040 USD
|
|
|
2015-08-24 |
2015-08-20 |
A
Achat
|
ADAGE CAPITAL PARTNERS GP LLC
Actionnaire important
|
13 600
+0.2%
14,31
194 616 USD
|
13 600
+0.2%
|
14,31
|
194 616 USD
|
|
|
2015-08-24 |
2015-08-20 |
A
Achat
|
ADAGE CAPITAL PARTNERS GP LLC
Actionnaire important
|
45 582
+0.8%
14,32
652 734 USD
|
45 582
+0.8%
|
14,32
|
652 734 USD
|
|
|
2015-08-24 |
2015-08-20 |
A
Achat
|
ADAGE CAPITAL PARTNERS GP LLC
Actionnaire important
|
103 818
+1.8%
14,28
1 482 521 USD
|
103 818
+1.8%
|
14,28
|
1 482 521 USD
|
|
|
2015-05-04 |
2015-04-30 |
A
Achat
|
ADAGE CAPITAL PARTNERS GP LLC
Actionnaire important
|
500 000
+9.7%
19,00
9 500 000 USD
|
500 000
+9.7%
|
19,00
|
9 500 000 USD
|
|
|
2015-02-20 |
2015-02-18 |
A
Achat
|
ADAGE CAPITAL PARTNERS GP LLC
Actionnaire important
|
684 762
+15.4%
7,50
5 135 715 USD
|
684 762
+15.4%
|
7,50
|
5 135 715 USD
|
|
|
2014-05-09 |
2014-05-09 |
V
Vente
|
BERMAN RICHARD J
Administrateur non-exécutif
|
7 530
-100.0%
2,63
19 823 USD
|
7 530
-100.0%
|
2,63
|
19 823 USD
|
|
|
2014-05-09 |
2014-05-09 |
V
Vente
|
BERMAN RICHARD J
Administrateur non-exécutif
|
7 000
-48.2%
2,63
18 425 USD
|
7 000
-48.2%
|
2,63
|
18 425 USD
|
|
|
2014-04-02 |
2014-03-31 |
A
Achat
|
O'Connor Daniel
Chief Executive Officer
Administrateur exécutif
|
3 333
+1.1%
3,00
9 999 USD
|
3 333
+1.1%
|
3,00
|
9 999 USD
|
|
|
2013-10-29 |
2013-10-24 |
A
Achat
|
PATTON JAMES P
Administrateur non-exécutif
|
25 000
+39.7%
4,00
100 000 USD
|
25 000
+39.7%
|
4,00
|
100 000 USD
|
|
|
2013-10-29 |
2013-10-24 |
A
Achat
|
APPEL RONI
Administrateur non-exécutif
|
12 500
+28.1%
4,00
50 000 USD
|
12 500
+28.1%
|
4,00
|
50 000 USD
|
|
|
2013-10-28 |
2013-10-24 |
A
Achat
|
PETIT ROBERT
Chief Scientific Officer
Dirigeant
|
12 800
+367.1%
4,00
51 200 USD
|
12 800
+367.1%
|
4,00
|
51 200 USD
|
|
|
2013-10-28 |
2013-10-24 |
A
Achat
|
Rosenblum Mark J
Chief Financial Officer
Dirigeant
|
12 000
+146.4%
4,00
48 000 USD
|
12 000
+146.4%
|
4,00
|
48 000 USD
|
|
|
2013-10-28 |
2013-10-24 |
A
Achat
|
O'Connor Daniel
Chief Executive Officer
Administrateur exécutif
|
13 500
+28.3%
4,00
54 000 USD
|
13 500
+28.3%
|
4,00
|
54 000 USD
|
|
|
2013-07-10 |
2012-11-23 |
V
Vente
|
BERMAN RICHARD J
Administrateur non-exécutif
|
100 000
-100.0%
0,04
3 500 USD
|
100 000
-100.0%
|
0,04
|
3 500 USD
|
|
|
2013-07-10 |
2012-11-21 |
V
Vente
|
BERMAN RICHARD J
Administrateur non-exécutif
|
82 694
-45.3%
0,04
3 308 USD
|
82 694
-45.3%
|
0,04
|
3 308 USD
|
|
|
2013-07-10 |
2012-11-21 |
V
Vente
|
BERMAN RICHARD J
Administrateur non-exécutif
|
127 632
-41.1%
0,04
4 480 USD
|
127 632
-41.1%
|
0,04
|
4 480 USD
|
|
|
2013-07-10 |
2012-11-21 |
V
Vente
|
BERMAN RICHARD J
Administrateur non-exécutif
|
67 306
-17.8%
0,04
2 524 USD
|
67 306
-17.8%
|
0,04
|
2 524 USD
|
|
|
2013-07-10 |
2012-11-20 |
V
Vente
|
BERMAN RICHARD J
Administrateur non-exécutif
|
150 000
-28.4%
0,04
5 550 USD
|
150 000
-28.4%
|
0,04
|
5 550 USD
|
|
|
2013-07-10 |
2012-11-20 |
V
Vente
|
BERMAN RICHARD J
Administrateur non-exécutif
|
150 000
-22.1%
0,04
5 400 USD
|
150 000
-22.1%
|
0,04
|
5 400 USD
|
|
|
2010-02-19 |
2010-02-12 |
V
Vente
|
BERMAN RICHARD J
Administrateur non-exécutif
|
760 624
-100.0%
0,16
121 700 USD
|
760 624
-100.0%
|
0,16
|
121 700 USD
|
|
|
2007-10-30 |
2007-10-25 |
A
Achat
|
COBB FREDRICK D
Vice President Finance
Dirigeant
|
40 695
+82.0%
0,18
7 325 USD
|
40 695
+82.0%
|
0,18
|
7 325 USD
|
|
|
2007-10-30 |
2007-10-25 |
A
Achat
|
ROTHMAN JOHN F
VP Clinical Development
Dirigeant
|
61 043
+28.4%
0,18
10 988 USD
|
61 043
+28.4%
|
0,18
|
10 988 USD
|
|
|
2007-10-26 |
2007-10-23 |
A
Achat
|
MOORE THOMAS A
CHAIRMAN / CEO
Administrateur exécutif
|
2 666 667
+inf%
0,15
400 000 USD
|
2 666 667
+inf%
|
0,15
|
400 000 USD
|
|
|
2007-03-01 |
2007-02-23 |
A
Achat
|
COBB FREDRICK D
Vice President Finance
Dirigeant
|
49 641
+inf%
0,16
7 943 USD
|
49 641
+inf%
|
0,16
|
7 943 USD
|
|
|
2007-03-01 |
2007-02-23 |
A
Achat
|
ROTHMAN JOHN F
VP of Clinical Development
Dirigeant
|
134 732
+168.4%
0,16
21 557 USD
|
134 732
+168.4%
|
0,16
|
21 557 USD
|
|
|
2007-01-10 |
2007-01-03 |
A
Achat
|
APPEL RONI
Administrateur non-exécutif
Actionnaire important
|
1 000 000
+33.6%
0,20
200 000 USD
|
1 000 000
+33.6%
|
0,20
|
200 000 USD
|
|
|
2007-01-10 |
2006-01-25 |
A
Achat
|
APPEL RONI
Administrateur non-exécutif
Actionnaire important
|
238 095
+10.0%
0,19
44 048 USD
|
238 095
+10.0%
|
0,19
|
44 048 USD
|
|
