Shire Human Genetic Therapies, Inc.

• Purchase • Sale • Planned purchase • Planned sale Net purchase Net sale Earnings

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Abbreviations B: Buy, S: Sell, PP: Planned purchase, PS: Planned sale, O: Option / Other

Notification date	Transaction date	B/S Transaction type	Nb. shares Price Value	Number of shares	Price	Value	Details
2020-06-05	2020-06-03	Translate Bio Inc (TBIO)	S Sale	40,086 -0.6% 19.75 USD 791,699	40,086 -0.6%	19.75	USD 791,699
2020-06-03	2020-06-02	Translate Bio Inc (TBIO)	S Sale	5,006 -0.1% 20.02 USD 100,220	5,006 -0.1%	20.02	USD 100,220
2020-06-03	2020-06-02	Translate Bio Inc (TBIO)	S Sale	100,389 -1.4% 19.75 USD 1,982,683	100,389 -1.4%	19.75	USD 1,982,683
2020-06-03	2020-06-01	Translate Bio Inc (TBIO)	S Sale	1,400 -0.0% 20.53 USD 28,742	1,400 -0.0%	20.53	USD 28,742
2020-06-03	2020-06-01	Translate Bio Inc (TBIO)	S Sale	107,072 -1.5% 19.85 USD 2,125,379	107,072 -1.5%	19.85	USD 2,125,379