Cruse Michael

• Purchase • Sale • Planned purchase • Planned sale Net purchase Net sale Earnings

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Abbreviations B: Buy, S: Sell, PP: Planned purchase, PS: Planned sale, O: Option / Other

Notification date	Transaction date	B/S Transaction type	Nb. shares Price Value	Number of shares	Price	Value	Details
2022-09-02	2022-09-01	Reneo Pharmaceuticals Inc (RPHM)	B Purchase	7,500 +121.0% 3.39 USD 25,448	7,500 +121.0%	3.39	USD 25,448
2022-08-31	2022-08-31	Reneo Pharmaceuticals Inc (RPHM)	B Purchase	3,212 +107.6% 3.21 USD 10,307	3,212 +107.6%	3.21	USD 10,307
2022-08-31	2022-08-30	Reneo Pharmaceuticals Inc (RPHM)	B Purchase	1,845 +161.8% 3.19 USD 5,893	1,845 +161.8%	3.19	USD 5,893
2022-08-31	2022-08-30	Reneo Pharmaceuticals Inc (RPHM)	B Purchase	975 +3.2% 3.16 USD 3,081	975 +3.2%	3.16	USD 3,081
2022-08-31	2022-08-29	Reneo Pharmaceuticals Inc (RPHM)	B Purchase	1,140 +inf% 3.24 USD 3,694	1,140 +inf%	3.24	USD 3,694
2022-08-31	2022-08-29	Reneo Pharmaceuticals Inc (RPHM)	PP Planned purchase	83 +0.3% 3.24 USD 269	83 +0.3%	3.24	USD 269