OrbiMed Israel GP Ltd.

• Purchase • Sale • Planned purchase • Planned sale Net purchase Net sale Earnings

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Abbreviations B: Buy, S: Sell, PP: Planned purchase, PS: Planned sale, O: Option / Other

Notification date	Transaction date	B/S Transaction type	Nb. shares Price Value	Number of shares	Price	Value	Details
2023-01-05	2023-01-03	Chemomab Therapeutics Ltd (CMMB)	S Sale	70,524 -3.1% 4.51 USD 318,063	70,524 -3.1%	4.51	USD 318,063
2023-01-05	2023-01-03	Chemomab Therapeutics Ltd (CMMB)	S Sale	266,376 -10.3% 3.34 USD 889,696	266,376 -10.3%	3.34	USD 889,696
2020-12-04	2020-12-02	Novus Therapeutics Inc (NVUS)	S Sale	103,200 -58.4% 21.60 USD 2,229,120	103,200 -58.4%	21.60	USD 2,229,120
2019-05-06	2019-05-02	Novus Therapeutics Inc (NVUS)	B Purchase	646,204 +25.5% 3.10 USD 2,003,232	646,204 +25.5%	3.10	USD 2,003,232