MORTIMER IAN

• Purchase • Sale • Planned purchase • Planned sale Net purchase Net sale Earnings

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Abbreviations B: Buy, S: Sell, PP: Planned purchase, PS: Planned sale, O: Option / Other

Notification date	Transaction date	B/S Transaction type	Nb. shares Price Value	Number of shares	Price	Value	Details
2025-01-27	2025-01-27	Xenon Pharmaceuticals Inc (XENE)	PS Planned sale	1,149 -3.5% 41.07 USD 47,189	1,149 -3.5%	41.07	USD 47,189
2025-01-27	2025-01-27	Xenon Pharmaceuticals Inc (XENE)	PS Planned sale	15,166 -32.6% 40.46 USD 613,616	15,166 -32.6%	40.46	USD 613,616
2025-01-27	2025-01-24	Xenon Pharmaceuticals Inc (XENE)	PS Planned sale	22,468 -41.8% 40.20 USD 903,214	22,468 -41.8%	40.20	USD 903,214
2025-01-27	2025-01-23	Xenon Pharmaceuticals Inc (XENE)	PS Planned sale	16,217 -34.1% 40.08 USD 649,977	16,217 -34.1%	40.08	USD 649,977
2023-05-26	2023-05-24	Xenon Pharmaceuticals Inc (XENE)	S Sale	1,407 -4.3% 41.49 USD 58,376	1,407 -4.3%	41.49	USD 58,376
2023-05-26	2023-05-24	Xenon Pharmaceuticals Inc (XENE)	S Sale	13,179 -32.2% 41.37 USD 545,215	13,179 -32.2%	41.37	USD 545,215
2023-05-26	2023-05-24	Xenon Pharmaceuticals Inc (XENE)	S Sale	17,069 -41.3% 41.44 USD 707,339	17,069 -41.3%	41.44	USD 707,339