Hannah Brendan

• Purchase • Sale • Planned purchase • Planned sale Net purchase Net sale Earnings

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Abbreviations B: Buy, S: Sell, PP: Planned purchase, PS: Planned sale, O: Option / Other

Notification date	Transaction date	B/S Transaction type	Nb. shares Price Value	Number of shares	Price	Value	Details
2024-08-21	2024-08-21	Cortexyme Inc (CRTX)	B Purchase	23,565 +8.6% 0.63 USD 14,846	23,565 +8.6%	0.63	USD 14,846
2024-08-21	2024-08-21	Cortexyme Inc (CRTX)	B Purchase	5,000 +1.9% 0.62 USD 3,100	5,000 +1.9%	0.62	USD 3,100
2024-08-21	2024-08-21	Cortexyme Inc (CRTX)	B Purchase	2,280 +0.9% 0.61 USD 1,391	2,280 +0.9%	0.61	USD 1,391
2024-08-21	2024-08-20	Cortexyme Inc (CRTX)	B Purchase	3,424 +1.3% 0.60 USD 2,054	3,424 +1.3%	0.60	USD 2,054
2024-08-21	2024-08-20	Cortexyme Inc (CRTX)	B Purchase	2,500 +1.0% 0.61 USD 1,525	2,500 +1.0%	0.61	USD 1,525
2024-08-21	2024-08-19	Cortexyme Inc (CRTX)	B Purchase	2,155 +0.8% 0.58 USD 1,250	2,155 +0.8%	0.58	USD 1,250
2023-08-09	2023-08-08	Cortexyme Inc (CRTX)	B Purchase	71,762 +55.3% 1.22 USD 87,550	71,762 +55.3%	1.22	USD 87,550