Rangwala Reshma

• Purchase • Sale • Planned purchase • Planned sale Net purchase Net sale Earnings

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Abbreviations B: Buy, S: Sell, PP: Planned purchase, PS: Planned sale, O: Option / Other

Notification date	Transaction date	B/S Transaction type	Nb. shares Price Value	Number of shares	Price	Value	Details
2025-03-06	2025-03-04	Karyopharm Therapeutics Inc (KPTI)	S Sale	3,587 -10.9% 6.29 USD 22,562	3,587 -10.9%	6.29	USD 22,562
2024-04-23	2024-04-22	Karyopharm Therapeutics Inc (KPTI)	S Sale	6,789 -1.9% 1.17 USD 7,943	6,789 -1.9%	1.17	USD 7,943
2024-03-04	2024-03-01	Karyopharm Therapeutics Inc (KPTI)	S Sale	5,969 -1.7% 1.20 USD 7,163	5,969 -1.7%	1.20	USD 7,163
2024-03-04	2024-02-29	Karyopharm Therapeutics Inc (KPTI)	S Sale	15,667 -4.2% 1.17 USD 18,330	15,667 -4.2%	1.17	USD 18,330
2023-04-24	2023-04-20	Karyopharm Therapeutics Inc (KPTI)	S Sale	6,655 -4.0% 4.05 USD 26,953	6,655 -4.0%	4.05	USD 26,953
2023-04-24	2023-04-20	Karyopharm Therapeutics Inc (KPTI)	S Sale	115 -0.1% 4.03 USD 463	115 -0.1%	4.03	USD 463