Samsara BioCapital GP, LLC

• Purchase • Sale • Planned purchase • Planned sale Net purchase Net sale Earnings

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Abbreviations B: Buy, S: Sell, PP: Planned purchase, PS: Planned sale, O: Option / Other

Notification date	Transaction date	B/S Transaction type	Nb. shares Price Value	Number of shares	Price	Value	Details
2025-03-17	2025-03-13	Mineralys Therapeutics Inc (MLYS)	B Purchase	600,000 +11.8% 13.50 USD 8,100,000	600,000 +11.8%	13.50	USD 8,100,000
2024-11-27	2024-11-26	Neoleukin Therapeutics Inc (NLTX)	B Purchase	2,000 +0.1% 27.50 USD 55,000	2,000 +0.1%	27.50	USD 55,000
2024-11-27	2024-11-26	Neoleukin Therapeutics Inc (NLTX)	B Purchase	15,219 +0.9% 26.73 USD 406,804	15,219 +0.9%	26.73	USD 406,804
2024-11-27	2024-11-26	Neoleukin Therapeutics Inc (NLTX)	B Purchase	10,803 +0.6% 26.01 USD 280,986	10,803 +0.6%	26.01	USD 280,986
2024-11-27	2024-11-26	Neoleukin Therapeutics Inc (NLTX)	B Purchase	20,748 +1.2% 24.91 USD 516,833	20,748 +1.2%	24.91	USD 516,833
2024-06-03	2024-05-30	CARGO Therapeutics Inc (CRGX)	B Purchase	294,000 +7.1% 17.00 USD 4,998,000	294,000 +7.1%	17.00	USD 4,998,000
2024-02-14	2024-02-12	Mineralys Therapeutics Inc (MLYS)	B Purchase	555,555 +12.3% 13.50 USD 7,499,993	555,555 +12.3%	13.50	USD 7,499,993
2023-11-16	2023-11-14	CARGO Therapeutics Inc (CRGX)	B Purchase	666,666 +19.3% 15.00 USD 9,999,990	666,666 +19.3%	15.00	USD 9,999,990
2023-10-18	2023-10-16	Scholar Rock Holding Corp (SRRK)	B Purchase	2,189,781 +47.6% 6.85 USD 15,000,000	2,189,781 +47.6%	6.85	USD 15,000,000