PATOU GARY

• Purchase • Sale • Planned purchase • Planned sale Net purchase Net sale Earnings

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Abbreviations B: Buy, S: Sell, PP: Planned purchase, PS: Planned sale, O: Option / Other

Notification date	Transaction date	B/S Transaction type	Nb. shares Price Value	Number of shares	Price	Value	Details
2024-11-22	2024-11-22	Xenon Pharmaceuticals Inc (XENE)	S Sale	2,040 -8.0% 41.05 USD 83,742	2,040 -8.0%	41.05	USD 83,742
2024-11-22	2024-11-22	Xenon Pharmaceuticals Inc (XENE)	S Sale	2,851 -10.8% 41.11 USD 117,205	2,851 -10.8%	41.11	USD 117,205
2023-12-15	2023-12-13	Xenon Pharmaceuticals Inc (XENE)	S Sale	7,598 -60.8% 41.05 USD 311,898	7,598 -60.8%	41.05	USD 311,898
2023-12-15	2023-12-13	Xenon Pharmaceuticals Inc (XENE)	S Sale	3,977 -14.4% 39.84 USD 158,444	3,977 -14.4%	39.84	USD 158,444
2023-12-15	2023-12-13	Xenon Pharmaceuticals Inc (XENE)	S Sale	2,303 -8.9% 39.10 USD 90,047	2,303 -8.9%	39.10	USD 90,047
2023-12-15	2023-12-13	Xenon Pharmaceuticals Inc (XENE)	S Sale	5,100 -17.8% 38.94 USD 198,594	5,100 -17.8%	38.94	USD 198,594
2022-11-28	2022-11-25	Xenon Pharmaceuticals Inc (XENE)	S Sale	1,937 -7.6% 34.79 USD 67,390	1,937 -7.6%	34.79	USD 67,390
2022-11-28	2022-11-23	Xenon Pharmaceuticals Inc (XENE)	S Sale	2,057 -8.0% 34.33 USD 70,610	2,057 -8.0%	34.33	USD 70,610