Espinoza Octavio

• Purchase • Sale • Planned purchase • Planned sale Net purchase Net sale Earnings

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Abbreviations B: Buy, S: Sell, PP: Planned purchase, PS: Planned sale, O: Option / Other

Notification date	Transaction date	B/S Transaction type	Nb. shares Price Value	Number of shares	Price	Value	Details
2025-03-06	2025-03-04	Ligand Pharmaceuticals Inc (LGND)	S Sale	5,000 -20.9% 115.03 USD 575,149	5,000 -20.9%	115.03	USD 575,149
2024-12-26	2024-12-23	Ligand Pharmaceuticals Inc (LGND)	S Sale	2,104 -9.2% 116.37 USD 244,850	2,104 -9.2%	116.37	USD 244,850
2024-09-24	2024-09-20	Ligand Pharmaceuticals Inc (LGND)	S Sale	800 -3.1% 103.95 USD 83,160	800 -3.1%	103.95	USD 83,160
2024-09-24	2024-09-20	Ligand Pharmaceuticals Inc (LGND)	S Sale	275 -1.1% 103.86 USD 28,562	275 -1.1%	103.86	USD 28,562
2024-09-24	2024-09-20	Ligand Pharmaceuticals Inc (LGND)	S Sale	200 -0.8% 103.98 USD 20,796	200 -0.8%	103.98	USD 20,796
2024-05-17	2024-05-17	Ligand Pharmaceuticals Inc (LGND)	S Sale	134 -0.6% 86.65 USD 11,611	134 -0.6%	86.65	USD 11,611
2024-05-17	2024-05-17	Ligand Pharmaceuticals Inc (LGND)	S Sale	5,022 -17.6% 86.67 USD 435,233	5,022 -17.6%	86.67	USD 435,233
2024-05-17	2024-05-16	Ligand Pharmaceuticals Inc (LGND)	S Sale	2,264 -9.5% 86.00 USD 194,712	2,264 -9.5%	86.00	USD 194,712
2024-05-17	2024-05-15	Ligand Pharmaceuticals Inc (LGND)	S Sale	5,873 -19.7% 86.01 USD 505,148	5,873 -19.7%	86.01	USD 505,148
2024-02-29	2024-02-28	Ligand Pharmaceuticals Inc (LGND)	S Sale	140 -0.5% 88.46 USD 12,384	140 -0.5%	88.46	USD 12,384
2022-11-10	2022-11-09	Ligand Pharmaceuticals Inc (LGND)	S Sale	1,696 -16.1% 75.64 USD 128,283	1,696 -16.1%	75.64	USD 128,283