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• Purchase • Sale • Planned purchase • Planned sale Net purchase Net sale Earnings

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Abbreviations B: Buy, S: Sell, PP: Planned purchase, PS: Planned sale, O: Option / Other

Notification date	Transaction date	B/S Transaction type	Nb. shares Price Value	Number of shares	Price	Value	Details
2017-07-05	2017-07-05	Acucela Inc (4589)	S Sale	1,175 -1.7% 6.75 USD 7,931	1,175 -1.7%	6.75	USD 7,931
2017-06-02	2017-06-01	Acucela Inc (4589)	S Sale	1,080 -1.5% 7.38 USD 7,970	1,080 -1.5%	7.38	USD 7,970
2017-05-02	2017-05-01	Acucela Inc (4589)	S Sale	1,100 -1.5% 6.15 USD 6,765	1,100 -1.5%	6.15	USD 6,765
2017-03-02	2017-03-02	Acucela Inc (4589)	S Sale	1,250 -1.7% 7.72 USD 9,650	1,250 -1.7%	7.72	USD 9,650
2017-02-03	2017-02-02	Acucela Inc (4589)	S Sale	1,250 -1.6% 8.50 USD 10,625	1,250 -1.6%	8.50	USD 10,625
2017-01-06	2017-01-04	Acucela Inc (4589)	S Sale	1,270 -1.6% 8.58 USD 10,897	1,270 -1.6%	8.58	USD 10,897