Meeker David P

• Purchase • Sale • Planned purchase • Planned sale Net purchase Net sale Earnings

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Abbreviations B: Buy, S: Sell, PP: Planned purchase, PS: Planned sale, O: Option / Other

Notification date	Transaction date	B/S Transaction type	Nb. shares Price Value	Number of shares	Price	Value	Details
2025-02-19	2025-02-19	Rhythm Pharmaceuticals Inc (RYTM)	PS Planned sale	9,896 -4.7% 57.22 USD 566,249	9,896 -4.7%	57.22	USD 566,249
2025-02-04	2025-02-04	Rhythm Pharmaceuticals Inc (RYTM)	PS Planned sale	4,278 -2.2% 59.43 USD 254,242	4,278 -2.2%	59.43	USD 254,242
2024-08-29	2024-08-27	Trevi Therapeutics Inc (TRVI)	S Sale	4,555 -1.3% 2.93 USD 13,353	4,555 -1.3%	2.93	USD 13,353
2024-03-19	2024-03-19	Rhythm Pharmaceuticals Inc (RYTM)	PS Planned sale	45,494 -20.7% 39.22 USD 1,784,275	45,494 -20.7%	39.22	USD 1,784,275
2024-02-05	2024-02-01	Rhythm Pharmaceuticals Inc (RYTM)	PS Planned sale	4,361 -3.5% 45.06 USD 196,507	4,361 -3.5%	45.06	USD 196,507
2019-05-13	2019-05-09	Trevi Therapeutics Inc (TRVI)	B Purchase	11,250 +3.3% 10.00 USD 112,500	11,250 +3.3%	10.00	USD 112,500