|
2021-11-12 |
2021-11-10 |
S
Sale
|
Van Hove Caroline F.
Executive Chairman
Non-Executive Director
|
6,087
-4.0%
5.67
USD 34,513
|
6,087
-4.0%
|
5.67
|
USD 34,513
|
|
|
2021-11-12 |
2021-11-10 |
S
Sale
|
Menezes Ronald
President and CEO
Executive Director
|
78,498
-15.5%
5.67
USD 445,084
|
78,498
-15.5%
|
5.67
|
USD 445,084
|
|
|
2021-10-07 |
2021-10-05 |
S
Sale
|
Bennett Oliver Christian
GC & Chief Compliance Officer
Officer
|
3,615
-4.5%
5.56
USD 20,099
|
3,615
-4.5%
|
5.56
|
USD 20,099
|
|
|
2021-08-12 |
2021-08-12 |
B
Purchase
|
Schmidt Andrew C
Chief Financial Officer
Officer
|
1,449
+3.0%
6.89
USD 9,976
|
1,449
+3.0%
|
6.89
|
USD 9,976
|
|
|
2021-04-08 |
2021-04-06 |
S
Sale
|
MILLER VALERIE J
VP, Controller and Interim CFO
Officer
|
1,508
-2.3%
7.13
USD 10,751
|
1,508
-2.3%
|
7.13
|
USD 10,751
|
|
|
2021-03-25 |
2021-03-12 |
S
Sale
|
MILLER VALERIE J
VP, Controller and Interim CFO
Officer
|
1,582
-2.4%
7.49
USD 11,849
|
1,582
-2.4%
|
7.49
|
USD 11,849
|
|
|
2021-02-03 |
2021-02-02 |
S
Sale
|
Little Paul Sean
Chief Financial Officer
Officer
|
4,123
-3.0%
4.91
USD 20,256
|
4,123
-3.0%
|
4.91
|
USD 20,256
|
|
|
2021-01-22 |
2021-01-20 |
S
Sale
|
Bennett Oliver Christian
GC & Chief Compliance Officer
Officer
|
4,399
-5.9%
4.49
USD 19,752
|
4,399
-5.9%
|
4.49
|
USD 19,752
|
|
|
2021-01-20 |
2021-01-13 |
S
Sale
|
Van Hove Caroline F.
Non-Executive Director
|
1,973
-1.4%
4.71
USD 9,301
|
1,973
-1.4%
|
4.71
|
USD 9,301
|
|
|
2020-02-20 |
2020-02-20 |
PS
Planned sale
|
Nugent Jeffrey M
Chairman of the Board and CEO
Executive Director
|
63,557
-23.2%
5.91
USD 375,368
|
63,557
-23.2%
|
5.91
|
USD 375,368
|
|
|
2020-02-20 |
2020-02-19 |
PS
Planned sale
|
Nugent Jeffrey M
Chairman of the Board and CEO
Executive Director
|
53,513
-16.4%
5.93
USD 317,113
|
53,513
-16.4%
|
5.93
|
USD 317,113
|
|
|
2020-02-20 |
2020-02-18 |
PS
Planned sale
|
Nugent Jeffrey M
Chairman of the Board and CEO
Executive Director
|
16,506
-4.8%
6.00
USD 98,960
|
16,506
-4.8%
|
6.00
|
USD 98,960
|
|
|
2019-06-11 |
2019-06-07 |
B
Purchase
|
Sullivan Keith J
|
20,869
+11.4%
5.75
USD 119,997
|
20,869
+11.4%
|
5.75
|
USD 119,997
|
|
|
2019-06-11 |
2019-06-07 |
B
Purchase
|
Little Paul Sean
Chief Financial Officer
|
17,391
+22.4%
5.75
USD 99,998
|
17,391
+22.4%
|
5.75
|
USD 99,998
|
|
|
2019-06-11 |
2019-06-07 |
B
Purchase
|
OBOYLE KEVIN C
|
8,696
+19.3%
5.75
USD 50,002
|
8,696
+19.3%
|
5.75
|
USD 50,002
|
|
|
2018-11-08 |
2018-11-06 |
PS
Planned sale
|
Haines Timothy
Non-Executive Director
|
81,137
-3.3%
21.60
USD 1,752,559
|
81,137
-3.3%
|
21.60
|
USD 1,752,559
|
|
|
2018-11-08 |
2018-11-06 |
PS
Planned sale
|
Haines Timothy
Non-Executive Director
|
8,514
-0.3%
21.13
USD 179,901
|
8,514
-0.3%
|
21.13
|
USD 179,901
|
|
|
2018-09-05 |
2018-08-31 |
S
Sale
|
Nugent Jeffrey M
Chairman of the Board and CEO
Executive Director
|
1,852
-0.6%
24.90
USD 46,115
|
1,852
-0.6%
|
24.90
|
USD 46,115
|
|
|
2018-05-09 |
2018-05-07 |
B
Purchase
|
Haines Timothy
Non-Executive Director
|
281,482
+12.8%
13.50
USD 3,800,007
|
281,482
+12.8%
|
13.50
|
USD 3,800,007
|
|
|
2018-05-09 |
2018-05-07 |
B
Purchase
|
Abingworth LLP
|
281,482
+12.8%
13.50
USD 3,800,007
|
281,482
+12.8%
|
13.50
|
USD 3,800,007
|
|
|
2018-05-09 |
2018-05-07 |
B
Purchase
|
SCHAISON PHILIPPE
Non-Executive Director
|
7,407
+24.4%
13.50
USD 99,995
|
7,407
+24.4%
|
13.50
|
USD 99,995
|
|
|
2018-05-09 |
2018-05-07 |
B
Purchase
|
Williams Patrick F.
Chief Financial Officer & SVP
Officer
|
7,408
+14.8%
13.50
USD 100,008
|
7,408
+14.8%
|
13.50
|
USD 100,008
|
|
|
2018-05-09 |
2018-05-07 |
B
Purchase
|
Nugent Jeffrey M
Chairman of the Board and CEO
Executive Director
|
1,852
+0.6%
13.50
USD 25,002
|
1,852
+0.6%
|
13.50
|
USD 25,002
|
|
|
2018-05-09 |
2018-05-07 |
B
Purchase
|
Sullivan Keith J
Non-Executive Director
|
7,407
+6.5%
13.50
USD 99,995
|
7,407
+6.5%
|
13.50
|
USD 99,995
|
|
|
2018-05-09 |
2018-05-07 |
B
Purchase
|
GREER R SCOTT
Non-Executive Director
|
11,111
+26.7%
13.50
USD 149,999
|
11,111
+26.7%
|
13.50
|
USD 149,999
|
|
|
2018-05-09 |
2018-05-07 |
B
Purchase
|
OBOYLE KEVIN C
Non-Executive Director
|
7,407
+23.5%
13.50
USD 99,995
|
7,407
+23.5%
|
13.50
|
USD 99,995
|
|
|
2015-10-13 |
2015-10-12 |
S
Sale
|
ORBIMED ADVISORS LLC
Large shareholder
|
2,785
-14.0%
5.98
USD 16,654
|
2,785
-14.0%
|
5.98
|
USD 16,654
|
|
|
2015-10-13 |
2015-10-12 |
S
Sale
|
ORBIMED ADVISORS LLC
Large shareholder
|
285,106
-13.9%
5.98
USD 1,704,934
|
285,106
-13.9%
|
5.98
|
USD 1,704,934
|
|
|
2015-10-09 |
2015-10-09 |
S
Sale
|
ORBIMED ADVISORS LLC
Large shareholder
|
2,041
-9.3%
7.03
USD 14,348
|
2,041
-9.3%
|
7.03
|
USD 14,348
|
|
|
2015-10-09 |
2015-10-09 |
S
Sale
|
ORBIMED ADVISORS LLC
Large shareholder
|
210,668
-9.3%
7.03
USD 1,480,996
|
210,668
-9.3%
|
7.03
|
USD 1,480,996
|
|
|
2015-10-09 |
2015-10-08 |
S
Sale
|
ORBIMED ADVISORS LLC
Large shareholder
|
3,837
-14.9%
7.24
USD 27,780
|
3,837
-14.9%
|
7.24
|
USD 27,780
|
|
|
2015-10-09 |
2015-10-08 |
S
Sale
|
ORBIMED ADVISORS LLC
Large shareholder
|
396,163
-14.9%
7.24
USD 2,868,220
|
396,163
-14.9%
|
7.24
|
USD 2,868,220
|
|
|
2015-10-09 |
2015-10-07 |
S
Sale
|
ORBIMED ADVISORS LLC
Large shareholder
|
454
-1.7%
7.36
USD 3,341
|
454
-1.7%
|
7.36
|
USD 3,341
|
|
|
2015-10-09 |
2015-10-07 |
S
Sale
|
ORBIMED ADVISORS LLC
Large shareholder
|
53,446
-2.0%
7.36
USD 393,363
|
53,446
-2.0%
|
7.36
|
USD 393,363
|
|
|
2015-10-06 |
2015-10-06 |
S
Sale
|
ORBIMED ADVISORS LLC
Large shareholder
|
59
-0.2%
7.80
USD 460
|
59
-0.2%
|
7.80
|
USD 460
|
|
|
2015-10-06 |
2015-10-06 |
S
Sale
|
ORBIMED ADVISORS LLC
Large shareholder
|
6,941
-0.3%
7.80
USD 54,140
|
6,941
-0.3%
|
7.80
|
USD 54,140
|
|
|
2015-10-06 |
2015-10-05 |
S
Sale
|
ORBIMED ADVISORS LLC
Large shareholder
|
1,163
-4.2%
8.19
USD 9,525
|
1,163
-4.2%
|
8.19
|
USD 9,525
|
|
|
2015-10-06 |
2015-10-05 |
S
Sale
|
ORBIMED ADVISORS LLC
Large shareholder
|
136,937
-4.8%
8.19
USD 1,121,514
|
136,937
-4.8%
|
8.19
|
USD 1,121,514
|
|
|
2015-10-06 |
2015-10-02 |
S
Sale
|
ORBIMED ADVISORS LLC
Large shareholder
|
403
-1.4%
10.34
USD 4,167
|
403
-1.4%
|
10.34
|
USD 4,167
|
|
|
2015-10-06 |
2015-10-02 |
S
Sale
|
ORBIMED ADVISORS LLC
Large shareholder
|
47,497
-1.6%
10.34
USD 491,119
|
47,497
-1.6%
|
10.34
|
USD 491,119
|
|
|
2015-10-01 |
2015-10-01 |
S
Sale
|
ORBIMED ADVISORS LLC
Large shareholder
|
400
-1.4%
10.34
USD 4,136
|
400
-1.4%
|
10.34
|
USD 4,136
|
|
|
2015-10-01 |
2015-10-01 |
S
Sale
|
ORBIMED ADVISORS LLC
Large shareholder
|
47,100
-1.6%
10.34
USD 487,014
|
47,100
-1.6%
|
10.34
|
USD 487,014
|
|
|
2015-10-01 |
2015-09-30 |
S
Sale
|
ORBIMED ADVISORS LLC
Large shareholder
|
369
-1.3%
10.17
USD 3,753
|
369
-1.3%
|
10.17
|
USD 3,753
|
|
|
2015-10-01 |
2015-09-30 |
S
Sale
|
ORBIMED ADVISORS LLC
Large shareholder
|
43,471
-1.5%
10.17
USD 442,100
|
43,471
-1.5%
|
10.17
|
USD 442,100
|
|
|
2015-10-01 |
2015-09-29 |
S
Sale
|
ORBIMED ADVISORS LLC
Large shareholder
|
89
-0.3%
10.08
USD 897
|
89
-0.3%
|
10.08
|
USD 897
|
|
|
2015-10-01 |
2015-09-29 |
S
Sale
|
ORBIMED ADVISORS LLC
Large shareholder
|
10,469
-0.3%
10.08
USD 105,528
|
10,469
-0.3%
|
10.08
|
USD 105,528
|
|
|
2015-09-28 |
2015-09-28 |
S
Sale
|
ORBIMED ADVISORS LLC
Large shareholder
|
89
-0.3%
10.30
USD 917
|
89
-0.3%
|
10.30
|
USD 917
|
|
|
2015-09-28 |
2015-09-28 |
S
Sale
|
ORBIMED ADVISORS LLC
Large shareholder
|
10,513
-0.3%
10.30
USD 108,284
|
10,513
-0.3%
|
10.30
|
USD 108,284
|
|
|
2015-09-28 |
2015-09-25 |
S
Sale
|
ORBIMED ADVISORS LLC
Large shareholder
|
311
-1.1%
11.07
USD 3,443
|
311
-1.1%
|
11.07
|
USD 3,443
|
|
|
2015-09-28 |
2015-09-25 |
S
Sale
|
ORBIMED ADVISORS LLC
Large shareholder
|
66,489
-2.2%
11.07
USD 736,033
|
66,489
-2.2%
|
11.07
|
USD 736,033
|
|
|
2015-09-28 |
2015-09-25 |
S
Sale
|
ORBIMED ADVISORS LLC
Large shareholder
|
800
-2.7%
10.07
USD 8,056
|
800
-2.7%
|
10.07
|
USD 8,056
|
|
|
2015-09-28 |
2015-09-25 |
S
Sale
|
ORBIMED ADVISORS LLC
Large shareholder
|
64,400
-2.0%
10.07
USD 648,508
|
64,400
-2.0%
|
10.07
|
USD 648,508
|
|
|
2015-09-28 |
2015-09-24 |
S
Sale
|
ORBIMED ADVISORS LLC
Large shareholder
|
8,152
-0.3%
11.00
USD 89,672
|
8,152
-0.3%
|
11.00
|
USD 89,672
|
|
|
2015-09-28 |
2015-09-24 |
S
Sale
|
ORBIMED ADVISORS LLC
Large shareholder
|
148
-0.5%
11.00
USD 1,628
|
148
-0.5%
|
11.00
|
USD 1,628
|
|
|
2015-09-28 |
2015-09-24 |
S
Sale
|
ORBIMED ADVISORS LLC
Large shareholder
|
6
-0.0%
9.78
USD 59
|
6
-0.0%
|
9.78
|
USD 59
|
|
|
2014-11-03 |
2014-10-29 |
B
Purchase
|
Haines Timothy
Non-Executive Director
Large shareholder
|
495,000
+29.0%
15.00
USD 7,425,000
|
495,000
+29.0%
|
15.00
|
USD 7,425,000
|
|
|
2014-10-31 |
2014-10-29 |
B
Purchase
|
Abingworth LLP
Large shareholder
|
495,000
+29.0%
15.00
USD 7,425,000
|
495,000
+29.0%
|
15.00
|
USD 7,425,000
|
|
