|
2008-11-19 |
2008-11-19 |
B
Purchase
|
Laikind Paul K
Chief Executive Officer
Officer
|
100
+0.0%
0.53
USD 53
|
100
+0.0%
|
0.53
|
USD 53
|
|
|
2008-11-19 |
2008-11-19 |
B
Purchase
|
Laikind Paul K
Chief Executive Officer
Officer
|
100
+0.0%
0.49
USD 49
|
100
+0.0%
|
0.49
|
USD 49
|
|
|
2008-11-19 |
2008-11-19 |
B
Purchase
|
Laikind Paul K
Chief Executive Officer
Officer
|
837
+0.1%
0.57
USD 477
|
837
+0.1%
|
0.57
|
USD 477
|
|
|
2008-11-19 |
2008-11-19 |
B
Purchase
|
Laikind Paul K
Chief Executive Officer
Officer
|
100
+0.0%
0.55
USD 55
|
100
+0.0%
|
0.55
|
USD 55
|
|
|
2008-11-19 |
2008-11-19 |
B
Purchase
|
Laikind Paul K
Chief Executive Officer
Officer
|
963
+0.1%
0.75
USD 722
|
963
+0.1%
|
0.75
|
USD 722
|
|
|
2008-11-19 |
2008-11-19 |
B
Purchase
|
Laikind Paul K
Chief Executive Officer
Officer
|
200
+0.0%
0.74
USD 148
|
200
+0.0%
|
0.74
|
USD 148
|
|
|
2008-11-19 |
2008-11-19 |
B
Purchase
|
Laikind Paul K
Chief Executive Officer
Officer
|
800
+0.1%
0.70
USD 560
|
800
+0.1%
|
0.70
|
USD 560
|
|
|
2008-11-19 |
2008-11-19 |
B
Purchase
|
Laikind Paul K
Chief Executive Officer
Officer
|
500
+0.1%
0.69
USD 345
|
500
+0.1%
|
0.69
|
USD 345
|
|
|
2008-11-19 |
2008-11-19 |
B
Purchase
|
Laikind Paul K
Chief Executive Officer
Officer
|
500
+0.1%
0.68
USD 340
|
500
+0.1%
|
0.68
|
USD 340
|
|
|
2008-11-19 |
2008-11-19 |
B
Purchase
|
Laikind Paul K
Chief Executive Officer
Officer
|
100
+0.0%
0.67
USD 67
|
100
+0.0%
|
0.67
|
USD 67
|
|
|
2008-11-19 |
2008-11-19 |
B
Purchase
|
Laikind Paul K
Chief Executive Officer
Officer
|
400
+0.1%
0.63
USD 252
|
400
+0.1%
|
0.63
|
USD 252
|
|
|
2008-11-19 |
2008-11-19 |
B
Purchase
|
Laikind Paul K
Chief Executive Officer
Officer
|
100
+0.0%
0.56
USD 56
|
100
+0.0%
|
0.56
|
USD 56
|
|
|
2008-11-19 |
2008-11-18 |
B
Purchase
|
Laikind Paul K
Chief Executive Officer
Officer
|
300
+0.0%
0.59
USD 177
|
300
+0.0%
|
0.59
|
USD 177
|
|
|
2008-11-19 |
2008-11-18 |
B
Purchase
|
Laikind Paul K
Chief Executive Officer
Officer
|
500
+0.1%
0.56
USD 280
|
500
+0.1%
|
0.56
|
USD 280
|
|
|
2008-11-19 |
2008-11-18 |
B
Purchase
|
Laikind Paul K
Chief Executive Officer
Officer
|
100
+0.0%
0.51
USD 51
|
100
+0.0%
|
0.51
|
USD 51
|
|
|
2008-04-18 |
2008-04-16 |
B
Purchase
|
ORONSKY ARNOLD L
Non-Executive Director
Large shareholder
|
45,239
+37.6%
2.34
USD 105,859
|
45,239
+37.6%
|
2.34
|
USD 105,859
|
|
|
2008-04-18 |
2008-04-16 |
B
Purchase
|
INTERWEST PARTNERS VII L P
Large shareholder
|
45,239
+37.6%
2.34
USD 105,859
|
45,239
+37.6%
|
2.34
|
USD 105,859
|
|
|
2008-04-18 |
2008-04-16 |
B
Purchase
|
EVNIN LUKE
Non-Executive Director
Large shareholder
|
71,866
+1.5%
2.34
USD 168,166
|
71,866
+1.5%
|
2.34
|
USD 168,166
|
|
|
2008-04-18 |
2008-04-16 |
B
Purchase
|
MPM BIOVENTURES II QP LP
Large shareholder
|
71,866
+1.5%
2.34
USD 168,166
|
71,866
+1.5%
|
2.34
|
USD 168,166
|
|
|
2008-04-18 |
2008-04-16 |
B
Purchase
|
ORONSKY ARNOLD L
Non-Executive Director
Large shareholder
|
945,577
+37.7%
2.34
USD 2,212,650
|
945,577
+37.7%
|
2.34
|
USD 2,212,650
|
|
|
2008-04-18 |
2008-04-16 |
B
Purchase
|
CREDIT SUISSE/
Large shareholder
|
196,633
+5.4%
2.34
USD 460,121
|
196,633
+5.4%
|
2.34
|
USD 460,121
|
|
|
2008-04-18 |
2008-04-16 |
B
Purchase
|
INTERWEST PARTNERS VII L P
Large shareholder
|
945,577
+37.7%
2.34
USD 2,212,650
|
945,577
+37.7%
|
2.34
|
USD 2,212,650
|
|
|
2008-04-17 |
2008-04-16 |
B
Purchase
|
HALE DAVID F
Non-Executive Director
|
10,000
+19.9%
2.34
USD 23,400
|
10,000
+19.9%
|
2.34
|
USD 23,400
|
|
|
2007-06-21 |
2007-06-19 |
PS
Planned sale
|
Beck John W
Chief Financial Officer
Officer
|
2,611
-1.1%
8.08
USD 21,097
|
2,611
-1.1%
|
8.08
|
USD 21,097
|
|
|
2007-06-21 |
2007-06-19 |
PS
Planned sale
|
Beck John W
Chief Financial Officer
Officer
|
100
-0.0%
8.06
USD 806
|
100
-0.0%
|
8.06
|
USD 806
|
|
|
2007-06-21 |
2007-06-19 |
PS
Planned sale
|
Beck John W
Chief Financial Officer
Officer
|
100
-0.0%
8.03
USD 803
|
100
-0.0%
|
8.03
|
USD 803
|
|
|
2007-06-21 |
2007-06-19 |
PS
Planned sale
|
Beck John W
Chief Financial Officer
Officer
|
100
-0.0%
8.04
USD 804
|
100
-0.0%
|
8.04
|
USD 804
|
|
|
2007-06-21 |
2007-06-19 |
PS
Planned sale
|
Beck John W
Chief Financial Officer
Officer
|
489
-0.2%
8.05
USD 3,936
|
489
-0.2%
|
8.05
|
USD 3,936
|
|
|
2007-06-05 |
2007-06-01 |
PS
Planned sale
|
Beck John W
Chief Financial Officer
Officer
|
400
-100.0%
8.01
USD 3,204
|
400
-100.0%
|
8.01
|
USD 3,204
|
|
|
2007-06-05 |
2007-06-01 |
PS
Planned sale
|
Beck John W
Chief Financial Officer
Officer
|
9,635
-96.0%
8.00
USD 77,080
|
9,635
-96.0%
|
8.00
|
USD 77,080
|
|
|
2007-05-24 |
2007-05-22 |
PS
Planned sale
|
Beck John W
Chief Financial Officer
Officer
|
300
-0.1%
8.00
USD 2,400
|
300
-0.1%
|
8.00
|
USD 2,400
|
|
|
2007-04-25 |
2007-04-25 |
PS
Planned sale
|
Beck John W
Chief Financial Officer
Officer
|
3,300
-1.4%
8.13
USD 26,829
|
3,300
-1.4%
|
8.13
|
USD 26,829
|
|
|
2007-04-25 |
2007-04-24 |
PS
Planned sale
|
Baracchini Edgardo Jr
Sr. VP of Business Development
Officer
|
1,800
-37.4%
8.24
USD 14,832
|
1,800
-37.4%
|
8.24
|
USD 14,832
|
|
|
2007-04-25 |
2007-04-24 |
PS
Planned sale
|
Baracchini Edgardo Jr
Sr. VP of Business Development
Officer
|
2,500
-34.2%
8.18
USD 20,450
|
2,500
-34.2%
|
8.18
|
USD 20,450
|
|
|
2007-04-10 |
2007-04-10 |
PS
Planned sale
|
Beck John W
Chief Financial Officer
Officer
|
6,172
-38.1%
8.00
USD 49,376
|
6,172
-38.1%
|
8.00
|
USD 49,376
|
|
|
2007-04-10 |
2007-04-09 |
PS
Planned sale
|
Beck John W
Chief Financial Officer
Officer
|
1,828
-10.1%
8.00
USD 14,624
|
1,828
-10.1%
|
8.00
|
USD 14,624
|
|
|
2007-02-28 |
2007-02-26 |
PS
Planned sale
|
Baracchini Edgardo Jr
Sr. VP of Business Development
Officer
|
700
-8.7%
8.00
USD 5,600
|
700
-8.7%
|
8.00
|
USD 5,600
|
|
|
2007-02-27 |
2007-02-26 |
PS
Planned sale
|
Beck John W
Chief Financial Officer
Officer
|
3,300
-1.3%
8.00
USD 26,400
|
3,300
-1.3%
|
8.00
|
USD 26,400
|
|
|
2006-12-05 |
2006-12-05 |
PS
Planned sale
|
Beck John W
Chief Financial Officer
Officer
|
3,000
-32.1%
8.00
USD 24,000
|
3,000
-32.1%
|
8.00
|
USD 24,000
|
|
|
2006-12-05 |
2006-12-05 |
PS
Planned sale
|
Beck John W
Chief Financial Officer
Officer
|
3,000
-32.1%
8.00
USD 24,000
|
3,000
-32.1%
|
8.00
|
USD 24,000
|
|
|
2006-12-05 |
2006-12-05 |
PS
Planned sale
|
Beck John W
Chief Financial Officer
Officer
|
3,000
-32.1%
8.00
USD 24,000
|
3,000
-32.1%
|
8.00
|
USD 24,000
|
|
|
2006-11-29 |
2006-11-27 |
PS
Planned sale
|
Beck John W
CFO
Officer
|
100
-0.0%
8.00
USD 800
|
100
-0.0%
|
8.00
|
USD 800
|
|
|
2006-11-29 |
2006-11-27 |
PS
Planned sale
|
Beck John W
CFO
Officer
|
200
-0.1%
8.01
USD 1,602
|
200
-0.1%
|
8.01
|
USD 1,602
|
|
|
2006-11-29 |
2006-11-27 |
PS
Planned sale
|
Beck John W
CFO
Officer
|
200
-0.1%
8.02
USD 1,604
|
200
-0.1%
|
8.02
|
USD 1,604
|
|
|
2006-11-13 |
2006-11-08 |
PS
Planned sale
|
Beck John W
Sr. VP, Finance & CFO
Officer
|
3,000
-24.3%
8.00
USD 24,000
|
3,000
-24.3%
|
8.00
|
USD 24,000
|
|
|
2006-11-13 |
2006-11-08 |
PS
Planned sale
|
Beck John W
Sr. VP, Finance & CFO
Officer
|
3,000
-24.3%
8.00
USD 24,000
|
3,000
-24.3%
|
8.00
|
USD 24,000
|
|
|
2006-11-13 |
2006-11-08 |
PS
Planned sale
|
Beck John W
Sr. VP, Finance & CFO
Officer
|
3,000
-24.3%
8.00
USD 24,000
|
3,000
-24.3%
|
8.00
|
USD 24,000
|
|
|
2006-11-07 |
2006-11-03 |
B
Purchase
|
CREDIT SUISSE/
Large shareholder
|
527,000
+17.4%
7.17
USD 3,776,324
|
527,000
+17.4%
|
7.17
|
USD 3,776,324
|
|
|
2006-06-28 |
2006-06-26 |
PS
Planned sale
|
Baracchini Edgardo Jr
Sr. VP, Business Development
Officer
|
250
-21.9%
8.35
USD 2,088
|
250
-21.9%
|
8.35
|
USD 2,088
|
|
|
2006-06-28 |
2006-06-26 |
PS
Planned sale
|
Baracchini Edgardo Jr
Sr. VP, Business Development
Officer
|
250
-21.9%
8.35
USD 2,088
|
250
-21.9%
|
8.35
|
USD 2,088
|
|
|
2006-05-24 |
2006-05-22 |
B
Purchase
|
CASH HARVEY B
Large shareholder
|
39,836
+391.9%
8.02
USD 319,648
|
39,836
+391.9%
|
8.02
|
USD 319,648
|
|
|
2006-05-24 |
2006-05-19 |
B
Purchase
|
CASH HARVEY B
Large shareholder
|
5,000
+96.8%
8.10
USD 40,500
|
5,000
+96.8%
|
8.10
|
USD 40,500
|
|
|
2006-05-24 |
2006-05-18 |
B
Purchase
|
CASH HARVEY B
Large shareholder
|
700
+15.7%
8.10
USD 5,670
|
700
+15.7%
|
8.10
|
USD 5,670
|
|
|
2006-05-24 |
2006-05-16 |
B
Purchase
|
CASH HARVEY B
Large shareholder
|
4,464
+inf%
8.00
USD 35,706
|
4,464
+inf%
|
8.00
|
USD 35,706
|
|
|
2007-03-09 |
2006-03-01 |
PS
Planned sale
|
Beck John W
Chief Financial Officer
Officer
|
1,000
-5.3%
8.00
USD 8,000
|
1,000
-5.3%
|
8.00
|
USD 8,000
|
|
|
2005-10-04 |
2005-09-30 |
B
Purchase
|
CREDIT SUISSE/
Large shareholder
|
341,297
+20.7%
5.86
USD 2,000,000
|
341,297
+20.7%
|
5.86
|
USD 2,000,000
|
|
|
2005-10-04 |
2005-09-30 |
B
Purchase
|
INTERWEST PARTNERS VII L P
Large shareholder
|
19,497
+19.4%
5.86
USD 114,252
|
19,497
+19.4%
|
5.86
|
USD 114,252
|
|
|
2005-10-04 |
2005-09-30 |
B
Purchase
|
INTERWEST PARTNERS VII L P
Large shareholder
|
407,124
+19.4%
5.86
USD 2,385,747
|
407,124
+19.4%
|
5.86
|
USD 2,385,747
|
|
|
2005-10-04 |
2005-09-30 |
B
Purchase
|
ORONSKY ARNOLD L
Non-Executive Director
Large shareholder
|
19,497
+19.4%
5.86
USD 114,252
|
19,497
+19.4%
|
5.86
|
USD 114,252
|
|
|
2005-10-04 |
2005-09-30 |
B
Purchase
|
ORONSKY ARNOLD L
Non-Executive Director
Large shareholder
|
407,124
+19.4%
5.86
USD 2,385,747
|
407,124
+19.4%
|
5.86
|
USD 2,385,747
|
|
|
2005-11-04 |
2005-09-07 |
B
Purchase
|
Gschwend Heinz W
Non-Executive Director
|
2,000
+5.7%
4.00
USD 8,000
|
2,000
+5.7%
|
4.00
|
USD 8,000
|
|
|
2005-11-04 |
2005-08-22 |
B
Purchase
|
Gschwend Heinz W
Non-Executive Director
|
3,000
+9.4%
4.36
USD 13,080
|
3,000
+9.4%
|
4.36
|
USD 13,080
|
|
|
2005-01-24 |
2004-12-22 |
B
Purchase
|
ORONSKY ARNOLD L
Non-Executive Director
Large shareholder
|
500
+inf%
6.84
USD 3,420
|
500
+inf%
|
6.84
|
USD 3,420
|
|
|
2004-06-23 |
2004-06-21 |
B
Purchase
|
INTERWEST PARTNERS VII L P
Large shareholder
|
5,941
+inf%
7.00
USD 41,587
|
5,941
+inf%
|
7.00
|
USD 41,587
|
|
|
2004-06-23 |
2004-06-21 |
B
Purchase
|
INTERWEST PARTNERS VII L P
Large shareholder
|
124,059
+inf%
7.00
USD 868,413
|
124,059
+inf%
|
7.00
|
USD 868,413
|
|
|
2004-06-23 |
2004-06-21 |
B
Purchase
|
INTERWEST PARTNERS VII L P
Large shareholder
|
5,941
+inf%
7.00
USD 41,587
|
5,941
+inf%
|
7.00
|
USD 41,587
|
|
|
2004-06-23 |
2004-06-21 |
B
Purchase
|
INTERWEST PARTNERS VII L P
Large shareholder
|
124,059
+inf%
7.00
USD 868,413
|
124,059
+inf%
|
7.00
|
USD 868,413
|
|
|
2004-06-23 |
2004-06-21 |
B
Purchase
|
ORONSKY ARNOLD L
Non-Executive Director
Large shareholder
|
5,941
+inf%
7.00
USD 41,587
|
5,941
+inf%
|
7.00
|
USD 41,587
|
|
|
2004-06-23 |
2004-06-21 |
B
Purchase
|
ORONSKY ARNOLD L
Non-Executive Director
Large shareholder
|
124,059
+inf%
7.00
USD 868,413
|
124,059
+inf%
|
7.00
|
USD 868,413
|
|
|
2004-06-21 |
2004-06-21 |
B
Purchase
|
MPM BIOVENTURES II QP LP
Large shareholder
|
357,000
+10.4%
7.00
USD 2,499,000
|
357,000
+10.4%
|
7.00
|
USD 2,499,000
|
|
|
2004-06-21 |
2004-06-21 |
B
Purchase
|
EVNIN LUKE
Non-Executive Director
Large shareholder
|
357,000
+10.4%
7.00
USD 2,499,000
|
357,000
+10.4%
|
7.00
|
USD 2,499,000
|
|
