|
2019-01-07 |
2019-01-07 |
PS
Planned sale
|
Brady Stephen R
EVP, Strategy & Finance
Officer
|
5,516
-5.4%
1.58
USD 8,722
|
5,516
-5.4%
|
1.58
|
USD 8,722
|
|
|
2019-01-07 |
2019-01-07 |
PS
Planned sale
|
Yurasov Sergey
Sr. VP, Clinic. Devel. & CMO
Officer
|
3,522
-4.3%
1.57
USD 5,536
|
3,522
-4.3%
|
1.57
|
USD 5,536
|
|
|
2019-01-07 |
2019-01-07 |
PS
Planned sale
|
Paya Carlos V
President and CEO
Executive Director
|
13,014
-7.7%
1.58
USD 20,591
|
13,014
-7.7%
|
1.58
|
USD 20,591
|
|
|
2019-01-07 |
2019-01-07 |
PS
Planned sale
|
ter Meulen Jan Henrik
Chief Scientific Officer
Officer
|
3,414
-3.9%
1.59
USD 5,415
|
3,414
-3.9%
|
1.59
|
USD 5,415
|
|
|
2018-12-04 |
2018-12-04 |
S
Sale
|
BVF PARTNERS L P/IL
Large shareholder
|
89,948
-19.5%
1.83
USD 164,929
|
89,948
-19.5%
|
1.83
|
USD 164,929
|
|
|
2018-12-04 |
2018-12-04 |
S
Sale
|
BVF PARTNERS L P/IL
Large shareholder
|
382,017
-16.4%
1.83
USD 700,466
|
382,017
-16.4%
|
1.83
|
USD 700,466
|
|
|
2018-12-04 |
2018-12-04 |
S
Sale
|
BVF PARTNERS L P/IL
Large shareholder
|
430,035
-14.7%
1.83
USD 788,512
|
430,035
-14.7%
|
1.83
|
USD 788,512
|
|
|
2018-01-08 |
2018-01-05 |
PS
Planned sale
|
ter Meulen Jan Henrik
Chief Scientific Officer
Officer
|
1,986
-4.8%
4.17
USD 8,282
|
1,986
-4.8%
|
4.17
|
USD 8,282
|
|
|
2018-01-08 |
2018-01-05 |
PS
Planned sale
|
Paya Carlos V
President and CEO
Executive Director
|
7,970
-7.0%
4.17
USD 33,247
|
7,970
-7.0%
|
4.17
|
USD 33,247
|
|
|
2018-01-08 |
2018-01-05 |
PS
Planned sale
|
Gombotz Wayne
Chief Development Officer
Officer
|
1,986
-5.1%
4.17
USD 8,282
|
1,986
-5.1%
|
4.17
|
USD 8,282
|
|
|
2018-01-08 |
2018-01-05 |
PS
Planned sale
|
Brady Stephen R
EVP, Strategy & Finance
Officer
|
3,328
-6.6%
4.17
USD 13,885
|
3,328
-6.6%
|
4.17
|
USD 13,885
|
|
|
2018-01-05 |
2018-01-04 |
S
Sale
|
Yurasov Sergey
Sr. VP, Clinic. Devel. & CMO
Officer
|
675
-2.4%
4.17
USD 2,816
|
675
-2.4%
|
4.17
|
USD 2,816
|
|
|
2017-11-06 |
2017-11-02 |
B
Purchase
|
COLEMAN LEWIS W
|
50,000
+40.0%
4.50
USD 225,000
|
50,000
+40.0%
|
4.50
|
USD 225,000
|
|
|
2017-11-01 |
2017-10-30 |
B
Purchase
|
BERGER FRANKLIN M
|
25,000
+50.0%
4.58
USD 114,375
|
25,000
+50.0%
|
4.58
|
USD 114,375
|
|
|
2017-10-31 |
2017-10-27 |
B
Purchase
|
COLEMAN LEWIS W
|
65,000
+108.3%
4.07
USD 264,752
|
65,000
+108.3%
|
4.07
|
USD 264,752
|
|
|
2017-10-30 |
2017-10-27 |
B
Purchase
|
COLUMN GROUP L P
Large shareholder
|
2,681,000
+67.7%
4.10
USD 10,992,100
|
2,681,000
+67.7%
|
4.10
|
USD 10,992,100
|
|
|
2017-10-27 |
2017-10-27 |
B
Purchase
|
Svennilson Peter
Non-Executive Director
Large shareholder
|
2,681,000
+inf%
4.10
USD 10,992,100
|
2,681,000
+inf%
|
4.10
|
USD 10,992,100
|
|
|
2017-10-26 |
2017-10-25 |
B
Purchase
|
BERGER FRANKLIN M
|
25,000
+100.0%
4.26
USD 106,620
|
25,000
+100.0%
|
4.26
|
USD 106,620
|
|
|
2017-08-03 |
2017-08-01 |
PS
Planned sale
|
Gombotz Wayne
Chief Development Officer
|
747
-3.1%
11.80
USD 8,813
|
747
-3.1%
|
11.80
|
USD 8,813
|
|
|
2017-08-03 |
2017-08-01 |
PS
Planned sale
|
Gombotz Wayne
Chief Development Officer
|
9,253
-28.0%
11.40
USD 105,523
|
9,253
-28.0%
|
11.40
|
USD 105,523
|
|
|
2017-07-12 |
2017-07-11 |
B
Purchase
|
COLEMAN LEWIS W
Non-Executive Director
|
2,000
+11.1%
9.33
USD 18,650
|
2,000
+11.1%
|
9.33
|
USD 18,650
|
|
|
2017-07-12 |
2017-07-10 |
B
Purchase
|
COLEMAN LEWIS W
Non-Executive Director
|
10,000
+125.0%
9.00
USD 89,950
|
10,000
+125.0%
|
9.00
|
USD 89,950
|
|
|
2017-07-10 |
2017-07-07 |
B
Purchase
|
COLEMAN LEWIS W
Non-Executive Director
|
4,000
+100.0%
9.15
USD 36,600
|
4,000
+100.0%
|
9.15
|
USD 36,600
|
|
|
2017-07-10 |
2017-07-06 |
B
Purchase
|
COLEMAN LEWIS W
Non-Executive Director
|
4,000
+inf%
9.39
USD 37,550
|
4,000
+inf%
|
9.39
|
USD 37,550
|
|
|
2017-05-22 |
2017-05-10 |
B
Purchase
|
GUTHART LEO
Large shareholder
|
5,000
+0.2%
6.14
USD 30,700
|
5,000
+0.2%
|
6.14
|
USD 30,700
|
|
|
2017-05-22 |
2017-05-09 |
B
Purchase
|
GUTHART LEO
Large shareholder
|
1,000
+0.0%
6.05
USD 6,050
|
1,000
+0.0%
|
6.05
|
USD 6,050
|
|
|
2017-05-22 |
2017-05-09 |
B
Purchase
|
GUTHART LEO
Large shareholder
|
6,000
+0.2%
6.06
USD 36,360
|
6,000
+0.2%
|
6.06
|
USD 36,360
|
|
|
2017-05-22 |
2017-05-09 |
B
Purchase
|
GUTHART LEO
Large shareholder
|
13,270
+0.4%
6.07
USD 80,549
|
13,270
+0.4%
|
6.07
|
USD 80,549
|
|
|
2017-05-22 |
2017-05-09 |
B
Purchase
|
GUTHART LEO
Large shareholder
|
4,730
+0.2%
6.12
USD 28,948
|
4,730
+0.2%
|
6.12
|
USD 28,948
|
|
|
2017-01-06 |
2017-01-04 |
PS
Planned sale
|
ter Meulen Jan Henrik
Chief Scientific Officer
|
980
-4.1%
5.35
USD 5,243
|
980
-4.1%
|
5.35
|
USD 5,243
|
|
|
2017-01-06 |
2017-01-04 |
PS
Planned sale
|
Paya Carlos V
President and CEO
Executive Director
|
3,940
-5.5%
5.35
USD 21,079
|
3,940
-5.5%
|
5.35
|
USD 21,079
|
|
|
2017-01-06 |
2017-01-04 |
PS
Planned sale
|
Brady Stephen R
EVP, Strategy & Finance
|
1,642
-5.1%
5.35
USD 8,785
|
1,642
-5.1%
|
5.35
|
USD 8,785
|
|
|
2017-01-06 |
2017-01-04 |
PS
Planned sale
|
Gombotz Wayne
Chief Development Officer
|
980
-4.1%
5.35
USD 5,243
|
980
-4.1%
|
5.35
|
USD 5,243
|
|
|
2016-12-27 |
2016-12-22 |
S
Sale
|
COLEMAN LEWIS W
Non-Executive Director
|
10,000
-20.0%
6.20
USD 62,039
|
10,000
-20.0%
|
6.20
|
USD 62,039
|
|
|
2016-12-20 |
2016-12-16 |
S
Sale
|
BERGER FRANKLIN M
Non-Executive Director
|
50,000
-66.7%
6.55
USD 327,330
|
50,000
-66.7%
|
6.55
|
USD 327,330
|
|
|
2016-09-22 |
2016-09-20 |
B
Purchase
|
COLUMN GROUP L P
Large shareholder
|
800,000
+25.3%
6.25
USD 5,000,000
|
800,000
+25.3%
|
6.25
|
USD 5,000,000
|
|
|
2016-09-20 |
2016-09-20 |
B
Purchase
|
COLEMAN LEWIS W
Non-Executive Director
|
40,000
+400.0%
6.25
USD 250,000
|
40,000
+400.0%
|
6.25
|
USD 250,000
|
|
|
2016-09-20 |
2016-09-20 |
B
Purchase
|
Svennilson Peter
Non-Executive Director
Large shareholder
|
800,000
+inf%
6.25
USD 5,000,000
|
800,000
+inf%
|
6.25
|
USD 5,000,000
|
|
|
2016-07-19 |
2016-07-15 |
B
Purchase
|
Brady Stephen R
EVP, Strategy & Finance
Officer
|
1,500
+9.6%
6.84
USD 10,255
|
1,500
+9.6%
|
6.84
|
USD 10,255
|
|
|
2015-11-24 |
2015-11-23 |
PS
Planned sale
|
Gombotz Wayne
Chief Development Officer
Officer
|
5,000
-99.3%
20.00
USD 100,000
|
5,000
-99.3%
|
20.00
|
USD 100,000
|
|
|
2015-09-16 |
2015-09-14 |
PS
Planned sale
|
Gombotz Wayne
Chief Development Officer
Officer
|
5,000
-99.3%
16.19
USD 80,955
|
5,000
-99.3%
|
16.19
|
USD 80,955
|
|
|
2015-08-26 |
2015-08-25 |
B
Purchase
|
COLEMAN LEWIS W
Non-Executive Director
|
3,000
+inf%
14.50
USD 43,500
|
3,000
+inf%
|
14.50
|
USD 43,500
|
|
|
2015-05-13 |
2015-05-12 |
S
Sale
|
ProQuest Investments IV, L.P.
Large shareholder
|
155,000
-7.2%
21.50
USD 3,332,500
|
155,000
-7.2%
|
21.50
|
USD 3,332,500
|
|
|
2015-05-13 |
2015-05-12 |
S
Sale
|
ProQuest Investments IV, L.P.
Large shareholder
|
22,607
-1.0%
22.26
USD 503,232
|
22,607
-1.0%
|
22.26
|
USD 503,232
|
|
|
2015-04-24 |
2015-04-24 |
S
Sale
|
ProQuest Investments IV, L.P.
Large shareholder
|
25,000
-1.1%
26.64
USD 666,000
|
25,000
-1.1%
|
26.64
|
USD 666,000
|
|
|
2015-04-24 |
2015-04-23 |
S
Sale
|
ProQuest Investments IV, L.P.
Large shareholder
|
22,643
-1.0%
27.35
USD 619,286
|
22,643
-1.0%
|
27.35
|
USD 619,286
|
|
|
2015-04-24 |
2015-04-23 |
S
Sale
|
ProQuest Investments IV, L.P.
Large shareholder
|
10,000
-0.5%
26.64
USD 266,400
|
10,000
-0.5%
|
26.64
|
USD 266,400
|
|
|
2015-04-24 |
2015-04-22 |
S
Sale
|
ProQuest Investments IV, L.P.
Large shareholder
|
25,249
-1.1%
26.56
USD 670,613
|
25,249
-1.1%
|
26.56
|
USD 670,613
|
|
|
2015-04-21 |
2015-04-21 |
S
Sale
|
ProQuest Investments IV, L.P.
Large shareholder
|
14,167
-0.6%
26.35
USD 373,300
|
14,167
-0.6%
|
26.35
|
USD 373,300
|
|
|
2015-04-21 |
2015-04-21 |
B
Purchase
|
BERGER FRANKLIN M
Non-Executive Director
|
25,000
+50.0%
26.50
USD 662,500
|
25,000
+50.0%
|
26.50
|
USD 662,500
|
|
|
2015-04-21 |
2015-04-21 |
B
Purchase
|
COLEMAN LEWIS W
Non-Executive Director
|
10,000
+inf%
26.50
USD 265,000
|
10,000
+inf%
|
26.50
|
USD 265,000
|
|
|
2015-04-21 |
2015-04-20 |
S
Sale
|
ProQuest Investments IV, L.P.
Large shareholder
|
12,792
-0.6%
26.44
USD 338,220
|
12,792
-0.6%
|
26.44
|
USD 338,220
|
|
|
2015-04-21 |
2015-04-17 |
S
Sale
|
ProQuest Investments IV, L.P.
Large shareholder
|
18,861
-0.8%
26.67
USD 503,023
|
18,861
-0.8%
|
26.67
|
USD 503,023
|
|
|
2015-04-16 |
2015-04-16 |
S
Sale
|
ProQuest Investments IV, L.P.
Large shareholder
|
100
-0.0%
26.75
USD 2,675
|
100
-0.0%
|
26.75
|
USD 2,675
|
|
|
2015-04-16 |
2015-04-15 |
S
Sale
|
ProQuest Investments IV, L.P.
Large shareholder
|
100
-0.0%
29.17
USD 2,917
|
100
-0.0%
|
29.17
|
USD 2,917
|
|
|
2015-04-16 |
2015-04-15 |
S
Sale
|
ProQuest Investments IV, L.P.
Large shareholder
|
39,900
-1.7%
28.57
USD 1,139,943
|
39,900
-1.7%
|
28.57
|
USD 1,139,943
|
|
|
2015-04-16 |
2015-04-14 |
S
Sale
|
ProQuest Investments IV, L.P.
Large shareholder
|
13,814
-0.6%
27.26
USD 376,570
|
13,814
-0.6%
|
27.26
|
USD 376,570
|
|
|
2015-04-08 |
2015-04-07 |
S
Sale
|
ProQuest Investments IV, L.P.
Large shareholder
|
3,600
-0.2%
26.55
USD 95,580
|
3,600
-0.2%
|
26.55
|
USD 95,580
|
|
|
2015-04-08 |
2015-04-06 |
S
Sale
|
ProQuest Investments IV, L.P.
Large shareholder
|
3,895
-0.2%
26.88
USD 104,698
|
3,895
-0.2%
|
26.88
|
USD 104,698
|
|
|
2015-04-02 |
2015-04-01 |
S
Sale
|
ProQuest Investments IV, L.P.
Large shareholder
|
8,035
-0.3%
27.07
USD 217,507
|
8,035
-0.3%
|
27.07
|
USD 217,507
|
|
|
2015-04-02 |
2015-04-01 |
S
Sale
|
ProQuest Investments IV, L.P.
Large shareholder
|
39,819
-1.7%
26.55
USD 1,057,194
|
39,819
-1.7%
|
26.55
|
USD 1,057,194
|
|
|
2015-04-02 |
2015-04-01 |
S
Sale
|
ProQuest Investments IV, L.P.
Large shareholder
|
14,600
-0.6%
25.51
USD 372,446
|
14,600
-0.6%
|
25.51
|
USD 372,446
|
|
|
2015-03-26 |
2015-03-25 |
S
Sale
|
ProQuest Investments IV, L.P.
Large shareholder
|
4,956
-0.2%
27.56
USD 136,587
|
4,956
-0.2%
|
27.56
|
USD 136,587
|
|
|
2015-03-26 |
2015-03-24 |
S
Sale
|
ProQuest Investments IV, L.P.
Large shareholder
|
13,200
-0.5%
27.67
USD 365,244
|
13,200
-0.5%
|
27.67
|
USD 365,244
|
|
|
2015-03-23 |
2015-03-23 |
S
Sale
|
ProQuest Investments IV, L.P.
Large shareholder
|
5,000
-0.2%
27.78
USD 138,900
|
5,000
-0.2%
|
27.78
|
USD 138,900
|
|
|
2015-03-23 |
2015-03-20 |
S
Sale
|
ProQuest Investments IV, L.P.
Large shareholder
|
84
-0.0%
28.15
USD 2,365
|
84
-0.0%
|
28.15
|
USD 2,365
|
|
|
2015-03-23 |
2015-03-20 |
S
Sale
|
ProQuest Investments IV, L.P.
Large shareholder
|
400
-0.0%
28.13
USD 11,252
|
400
-0.0%
|
28.13
|
USD 11,252
|
|
|
2015-03-23 |
2015-03-20 |
S
Sale
|
ProQuest Investments IV, L.P.
Large shareholder
|
200
-0.0%
28.04
USD 5,608
|
200
-0.0%
|
28.04
|
USD 5,608
|
|
|
2015-03-23 |
2015-03-20 |
S
Sale
|
ProQuest Investments IV, L.P.
Large shareholder
|
8,780
-0.4%
27.19
USD 238,749
|
8,780
-0.4%
|
27.19
|
USD 238,749
|
|
|
2015-03-23 |
2015-03-19 |
S
Sale
|
ProQuest Investments IV, L.P.
Large shareholder
|
200
-0.0%
28.07
USD 5,614
|
200
-0.0%
|
28.07
|
USD 5,614
|
|
|
2015-03-23 |
2015-03-19 |
S
Sale
|
ProQuest Investments IV, L.P.
Large shareholder
|
29,800
-1.2%
27.55
USD 820,990
|
29,800
-1.2%
|
27.55
|
USD 820,990
|
|
|
2015-03-18 |
2015-03-18 |
S
Sale
|
ProQuest Investments IV, L.P.
Large shareholder
|
100
-0.0%
27.02
USD 2,702
|
100
-0.0%
|
27.02
|
USD 2,702
|
|
|
2015-03-18 |
2015-03-18 |
S
Sale
|
ProQuest Investments IV, L.P.
Large shareholder
|
500
-0.0%
26.99
USD 13,495
|
500
-0.0%
|
26.99
|
USD 13,495
|
|
|
2015-03-18 |
2015-03-18 |
S
Sale
|
ProQuest Investments IV, L.P.
Large shareholder
|
100
-0.0%
27.04
USD 2,704
|
100
-0.0%
|
27.04
|
USD 2,704
|
|
|
2015-03-18 |
2015-03-18 |
S
Sale
|
ProQuest Investments IV, L.P.
Large shareholder
|
19,300
-0.8%
26.56
USD 512,608
|
19,300
-0.8%
|
26.56
|
USD 512,608
|
|
