|
2015-03-17 |
2015-03-17 |
PS
Planned sale
|
Nash Christine A
SVP & Chief Commercial Officer
Officer
|
10,000
-34.5%
37.56
USD 375,600
|
10,000
-34.5%
|
37.56
|
USD 375,600
|
|
|
2015-03-13 |
2015-03-10 |
PS
Planned sale
|
Nash Christine A
SVP & Chief Commercial Officer
Officer
|
10,000
-34.5%
35.08
USD 350,800
|
10,000
-34.5%
|
35.08
|
USD 350,800
|
|
|
2015-03-10 |
2015-03-10 |
PS
Planned sale
|
Nash Christine A
SVP & Chief Commercial Officer
Officer
|
1,450
-7.1%
30.10
USD 43,645
|
1,450
-7.1%
|
30.10
|
USD 43,645
|
|
|
2015-03-10 |
2015-03-09 |
PS
Planned sale
|
Nash Christine A
SVP & Chief Commercial Officer
Officer
|
2,800
-12.0%
30.00
USD 84,000
|
2,800
-12.0%
|
30.00
|
USD 84,000
|
|
|
2015-03-03 |
2015-02-27 |
S
Sale
|
Scharschmidt Bruce Frederick
SVP & Chief Medical Officer
Officer
|
4,804
-16.4%
30.43
USD 146,186
|
4,804
-16.4%
|
30.43
|
USD 146,186
|
|
|
2015-03-03 |
2015-02-27 |
S
Sale
|
Scharschmidt Bruce Frederick
SVP & Chief Medical Officer
Officer
|
24,996
-46.1%
29.79
USD 744,631
|
24,996
-46.1%
|
29.79
|
USD 744,631
|
|
|
2015-01-22 |
2015-01-20 |
PS
Planned sale
|
Nash Christine A
SVP & Chief Commercial Officer
Officer
|
2,500
-8.0%
25.27
USD 63,175
|
2,500
-8.0%
|
25.27
|
USD 63,175
|
|
|
2014-06-09 |
2014-06-06 |
S
Sale
|
BARRETT M JAMES
Large shareholder
|
1,134
-100.0%
26.90
USD 30,506
|
1,134
-100.0%
|
26.90
|
USD 30,506
|
|
|
2014-06-09 |
2014-06-06 |
S
Sale
|
BARRETT M JAMES
Large shareholder
|
148
-100.0%
26.80
USD 3,966
|
148
-100.0%
|
26.80
|
USD 3,966
|
|
|
2014-06-09 |
2014-06-06 |
S
Sale
|
BASKETT FOREST
Large shareholder
|
1,134
-100.0%
26.90
USD 30,506
|
1,134
-100.0%
|
26.90
|
USD 30,506
|
|
|
2014-06-09 |
2014-06-06 |
S
Sale
|
SANDELL SCOTT D
Large shareholder
|
296
-100.0%
26.74
USD 7,915
|
296
-100.0%
|
26.74
|
USD 7,915
|
|
|
2014-06-09 |
2014-06-06 |
S
Sale
|
BARRIS PETER J
Large shareholder
|
1,134
-100.0%
26.90
USD 30,506
|
1,134
-100.0%
|
26.90
|
USD 30,506
|
|
|
2014-06-09 |
2014-06-06 |
S
Sale
|
BARRETT M JAMES
Large shareholder
|
148
-100.0%
26.77
USD 3,962
|
148
-100.0%
|
26.77
|
USD 3,962
|
|
|
2014-06-09 |
2014-06-06 |
S
Sale
|
DRANT RYAN D
Large shareholder
|
1,134
-100.0%
26.90
USD 30,506
|
1,134
-100.0%
|
26.90
|
USD 30,506
|
|
|
2014-06-09 |
2014-06-06 |
S
Sale
|
BASKETT FOREST
Large shareholder
|
243
-100.0%
26.87
USD 6,530
|
243
-100.0%
|
26.87
|
USD 6,530
|
|
|
2014-06-06 |
2014-06-06 |
S
Sale
|
KOLLURI KRISHNA KITTU
Large shareholder
|
10
-100.0%
27.19
USD 272
|
10
-100.0%
|
27.19
|
USD 272
|
|
|
2014-06-06 |
2014-06-06 |
S
Sale
|
KOLLURI KRISHNA KITTU
Large shareholder
|
10
-100.0%
27.19
USD 272
|
10
-100.0%
|
27.19
|
USD 272
|
|
|
2014-06-06 |
2014-06-06 |
S
Sale
|
KOLLURI KRISHNA KITTU
Large shareholder
|
100
-100.0%
27.19
USD 2,719
|
100
-100.0%
|
27.19
|
USD 2,719
|
|
|
2014-06-06 |
2014-06-04 |
S
Sale
|
HEALY JAMES
Non-Executive Director
|
417,747
-17.7%
27.70
USD 11,571,592
|
417,747
-17.7%
|
27.70
|
USD 11,571,592
|
|
|
2014-06-06 |
2014-06-04 |
S
Sale
|
SOFINNOVA VENTURE PARTNERS VII L P
Large shareholder
|
417,747
-17.7%
27.70
USD 11,571,592
|
417,747
-17.7%
|
27.70
|
USD 11,571,592
|
|
|
2014-03-10 |
2014-03-06 |
PS
Planned sale
|
Nash Christine A
SVP & Chief Commercial Officer
Officer
|
100
-0.7%
30.05
USD 3,005
|
100
-0.7%
|
30.05
|
USD 3,005
|
|
|
2014-03-10 |
2014-03-06 |
PS
Planned sale
|
Nash Christine A
SVP & Chief Commercial Officer
Officer
|
5,000
-24.9%
29.03
USD 145,130
|
5,000
-24.9%
|
29.03
|
USD 145,130
|
|
|
2014-03-05 |
2014-03-04 |
PS
Planned sale
|
HEALY JAMES
Non-Executive Director
Large shareholder
|
23,625
-100.0%
30.02
USD 709,223
|
23,625
-100.0%
|
30.02
|
USD 709,223
|
|
|
2014-01-14 |
2014-01-14 |
S
Sale
|
Nash Christine A
SVP & Chief Commercial Officer
Officer
|
1,100
-17.7%
24.01
USD 26,412
|
1,100
-17.7%
|
24.01
|
USD 26,412
|
|
|
2014-01-14 |
2014-01-10 |
S
Sale
|
Nash Christine A
SVP & Chief Commercial Officer
Officer
|
8,900
-98.9%
24.10
USD 214,489
|
8,900
-98.9%
|
24.10
|
USD 214,489
|
|
|
2013-09-23 |
2013-09-20 |
S
Sale
|
Highland Management Partners VII, LLC
Large shareholder
|
83
-0.2%
25.81
USD 2,142
|
83
-0.2%
|
25.81
|
USD 2,142
|
|
|
2013-09-23 |
2013-09-20 |
S
Sale
|
Highland Management Partners VII, LLC
Large shareholder
|
933
-0.2%
25.81
USD 24,081
|
933
-0.2%
|
25.81
|
USD 24,081
|
|
|
2013-09-23 |
2013-09-20 |
S
Sale
|
Highland Management Partners VII, LLC
Large shareholder
|
641
-0.2%
25.81
USD 16,544
|
641
-0.2%
|
25.81
|
USD 16,544
|
|
|
2013-09-23 |
2013-09-20 |
S
Sale
|
Highland Management Partners VII, LLC
Large shareholder
|
2,643
-0.2%
25.81
USD 68,216
|
2,643
-0.2%
|
25.81
|
USD 68,216
|
|
|
2013-09-23 |
2013-09-19 |
S
Sale
|
Highland Management Partners VII, LLC
Large shareholder
|
28
-0.1%
25.93
USD 726
|
28
-0.1%
|
25.93
|
USD 726
|
|
|
2013-09-23 |
2013-09-19 |
S
Sale
|
Highland Management Partners VII, LLC
Large shareholder
|
315
-0.1%
25.93
USD 8,168
|
315
-0.1%
|
25.93
|
USD 8,168
|
|
|
2013-09-23 |
2013-09-19 |
S
Sale
|
Highland Management Partners VII, LLC
Large shareholder
|
217
-0.1%
25.93
USD 5,627
|
217
-0.1%
|
25.93
|
USD 5,627
|
|
|
2013-09-23 |
2013-09-19 |
S
Sale
|
Highland Management Partners VII, LLC
Large shareholder
|
894
-0.1%
25.93
USD 23,181
|
894
-0.1%
|
25.93
|
USD 23,181
|
|
|
2013-09-19 |
2013-09-18 |
S
Sale
|
Highland Management Partners VII, LLC
Large shareholder
|
111
-0.3%
26.03
USD 2,889
|
111
-0.3%
|
26.03
|
USD 2,889
|
|
|
2013-09-19 |
2013-09-18 |
S
Sale
|
Highland Management Partners VII, LLC
Large shareholder
|
1,252
-0.3%
26.03
USD 32,590
|
1,252
-0.3%
|
26.03
|
USD 32,590
|
|
|
2013-09-19 |
2013-09-18 |
S
Sale
|
Highland Management Partners VII, LLC
Large shareholder
|
860
-0.3%
26.03
USD 22,386
|
860
-0.3%
|
26.03
|
USD 22,386
|
|
|
2013-09-19 |
2013-09-18 |
S
Sale
|
Highland Management Partners VII, LLC
Large shareholder
|
3,547
-0.3%
26.03
USD 92,328
|
3,547
-0.3%
|
26.03
|
USD 92,328
|
|
|
2013-09-19 |
2013-09-17 |
S
Sale
|
Highland Management Partners VII, LLC
Large shareholder
|
188
-0.5%
25.99
USD 4,886
|
188
-0.5%
|
25.99
|
USD 4,886
|
|
|
2013-09-19 |
2013-09-17 |
S
Sale
|
Highland Management Partners VII, LLC
Large shareholder
|
2,121
-0.5%
25.99
USD 55,125
|
2,121
-0.5%
|
25.99
|
USD 55,125
|
|
|
2013-09-19 |
2013-09-17 |
S
Sale
|
Highland Management Partners VII, LLC
Large shareholder
|
1,456
-0.5%
25.99
USD 37,841
|
1,456
-0.5%
|
25.99
|
USD 37,841
|
|
|
2013-09-19 |
2013-09-17 |
S
Sale
|
Highland Management Partners VII, LLC
Large shareholder
|
6,009
-0.5%
25.99
USD 156,174
|
6,009
-0.5%
|
25.99
|
USD 156,174
|
|
|
2013-09-17 |
2013-09-16 |
S
Sale
|
Highland Management Partners VII, LLC
Large shareholder
|
119
-0.3%
26.22
USD 3,120
|
119
-0.3%
|
26.22
|
USD 3,120
|
|
|
2013-09-17 |
2013-09-16 |
S
Sale
|
Highland Management Partners VII, LLC
Large shareholder
|
1,345
-0.3%
26.22
USD 35,266
|
1,345
-0.3%
|
26.22
|
USD 35,266
|
|
|
2013-09-17 |
2013-09-16 |
S
Sale
|
Highland Management Partners VII, LLC
Large shareholder
|
924
-0.3%
26.22
USD 24,227
|
924
-0.3%
|
26.22
|
USD 24,227
|
|
|
2013-09-17 |
2013-09-16 |
S
Sale
|
Highland Management Partners VII, LLC
Large shareholder
|
3,812
-0.3%
26.22
USD 99,951
|
3,812
-0.3%
|
26.22
|
USD 99,951
|
|
|
2013-09-17 |
2013-09-13 |
S
Sale
|
Highland Management Partners VII, LLC
Large shareholder
|
40
-0.1%
26.50
USD 1,060
|
40
-0.1%
|
26.50
|
USD 1,060
|
|
|
2013-09-17 |
2013-09-13 |
S
Sale
|
Highland Management Partners VII, LLC
Large shareholder
|
456
-0.1%
26.50
USD 12,084
|
456
-0.1%
|
26.50
|
USD 12,084
|
|
|
2013-09-17 |
2013-09-13 |
S
Sale
|
Highland Management Partners VII, LLC
Large shareholder
|
313
-0.1%
26.50
USD 8,295
|
313
-0.1%
|
26.50
|
USD 8,295
|
|
|
2013-09-17 |
2013-09-13 |
S
Sale
|
Highland Management Partners VII, LLC
Large shareholder
|
1,291
-0.1%
26.50
USD 34,212
|
1,291
-0.1%
|
26.50
|
USD 34,212
|
|
|
2013-09-12 |
2013-09-11 |
S
Sale
|
Highland Management Partners VII, LLC
Large shareholder
|
88
-0.2%
27.08
USD 2,383
|
88
-0.2%
|
27.08
|
USD 2,383
|
|
|
2013-09-12 |
2013-09-11 |
S
Sale
|
Highland Management Partners VII, LLC
Large shareholder
|
992
-0.2%
27.08
USD 26,863
|
992
-0.2%
|
27.08
|
USD 26,863
|
|
|
2013-09-12 |
2013-09-11 |
S
Sale
|
Highland Management Partners VII, LLC
Large shareholder
|
681
-0.2%
27.08
USD 18,441
|
681
-0.2%
|
27.08
|
USD 18,441
|
|
|
2013-09-12 |
2013-09-11 |
S
Sale
|
Highland Management Partners VII, LLC
Large shareholder
|
2,812
-0.2%
27.08
USD 76,149
|
2,812
-0.2%
|
27.08
|
USD 76,149
|
|
|
2013-09-12 |
2013-09-10 |
S
Sale
|
Highland Management Partners VII, LLC
Large shareholder
|
578
-1.5%
26.48
USD 15,305
|
578
-1.5%
|
26.48
|
USD 15,305
|
|
|
2013-09-12 |
2013-09-10 |
S
Sale
|
Highland Management Partners VII, LLC
Large shareholder
|
6,509
-1.4%
26.48
USD 172,358
|
6,509
-1.4%
|
26.48
|
USD 172,358
|
|
|
2013-09-12 |
2013-09-10 |
S
Sale
|
Highland Management Partners VII, LLC
Large shareholder
|
4,469
-1.4%
26.48
USD 118,339
|
4,469
-1.4%
|
26.48
|
USD 118,339
|
|
|
2013-09-12 |
2013-09-10 |
S
Sale
|
Highland Management Partners VII, LLC
Large shareholder
|
18,444
-1.4%
26.48
USD 488,397
|
18,444
-1.4%
|
26.48
|
USD 488,397
|
|
|
2013-09-10 |
2013-09-09 |
S
Sale
|
Highland Management Partners VII, LLC
Large shareholder
|
346
-0.9%
26.06
USD 9,017
|
346
-0.9%
|
26.06
|
USD 9,017
|
|
|
2013-09-10 |
2013-09-09 |
S
Sale
|
Highland Management Partners VII, LLC
Large shareholder
|
3,894
-0.9%
26.06
USD 101,478
|
3,894
-0.9%
|
26.06
|
USD 101,478
|
|
|
2013-09-10 |
2013-09-09 |
S
Sale
|
Highland Management Partners VII, LLC
Large shareholder
|
2,674
-0.9%
26.06
USD 69,684
|
2,674
-0.9%
|
26.06
|
USD 69,684
|
|
|
2013-09-10 |
2013-09-09 |
S
Sale
|
Highland Management Partners VII, LLC
Large shareholder
|
11,034
-0.9%
26.06
USD 287,546
|
11,034
-0.9%
|
26.06
|
USD 287,546
|
|
|
2013-09-10 |
2013-09-06 |
S
Sale
|
Highland Management Partners VII, LLC
Large shareholder
|
2
-0.0%
25.50
USD 51
|
2
-0.0%
|
25.50
|
USD 51
|
|
|
2013-09-10 |
2013-09-06 |
S
Sale
|
Highland Management Partners VII, LLC
Large shareholder
|
22
-0.0%
25.50
USD 561
|
22
-0.0%
|
25.50
|
USD 561
|
|
|
2013-09-10 |
2013-09-06 |
S
Sale
|
Highland Management Partners VII, LLC
Large shareholder
|
15
-0.0%
25.50
USD 383
|
15
-0.0%
|
25.50
|
USD 383
|
|
|
2013-09-10 |
2013-09-06 |
S
Sale
|
Highland Management Partners VII, LLC
Large shareholder
|
61
-0.0%
25.50
USD 1,556
|
61
-0.0%
|
25.50
|
USD 1,556
|
|
|
2013-08-07 |
2013-08-05 |
S
Sale
|
Highland Management Partners VII, LLC
Large shareholder
|
482
-1.2%
25.48
USD 12,281
|
482
-1.2%
|
25.48
|
USD 12,281
|
|
|
2013-08-07 |
2013-08-05 |
S
Sale
|
Highland Management Partners VII, LLC
Large shareholder
|
5,424
-1.2%
25.48
USD 138,204
|
5,424
-1.2%
|
25.48
|
USD 138,204
|
|
|
2013-08-07 |
2013-08-05 |
S
Sale
|
Highland Management Partners VII, LLC
Large shareholder
|
3,725
-1.2%
25.48
USD 94,913
|
3,725
-1.2%
|
25.48
|
USD 94,913
|
|
|
2013-08-07 |
2013-08-05 |
S
Sale
|
Highland Management Partners VII, LLC
Large shareholder
|
15,369
-1.2%
25.48
USD 391,602
|
15,369
-1.2%
|
25.48
|
USD 391,602
|
|
|
2013-08-05 |
2013-08-02 |
S
Sale
|
Highland Management Partners VII, LLC
Large shareholder
|
52
-0.1%
25.37
USD 1,319
|
52
-0.1%
|
25.37
|
USD 1,319
|
|
|
2013-08-05 |
2013-08-02 |
S
Sale
|
Highland Management Partners VII, LLC
Large shareholder
|
587
-0.1%
25.37
USD 14,892
|
587
-0.1%
|
25.37
|
USD 14,892
|
|
|
2013-08-05 |
2013-08-02 |
S
Sale
|
Highland Management Partners VII, LLC
Large shareholder
|
403
-0.1%
25.37
USD 10,224
|
403
-0.1%
|
25.37
|
USD 10,224
|
|
|
2013-08-05 |
2013-08-02 |
S
Sale
|
Highland Management Partners VII, LLC
Large shareholder
|
1,665
-0.1%
25.37
USD 42,241
|
1,665
-0.1%
|
25.37
|
USD 42,241
|
|
|
2013-08-05 |
2013-08-01 |
S
Sale
|
Highland Management Partners VII, LLC
Large shareholder
|
858
-2.1%
25.35
USD 21,750
|
858
-2.1%
|
25.35
|
USD 21,750
|
|
|
2013-08-05 |
2013-08-01 |
S
Sale
|
Highland Management Partners VII, LLC
Large shareholder
|
9,663
-2.1%
25.35
USD 244,957
|
9,663
-2.1%
|
25.35
|
USD 244,957
|
|
