|
2011-12-05 |
2011-12-01 |
S
Sale
|
Berrey M Michelle
Chief Medical Officer
Officer
|
3,126
-100.0%
130.33
USD 407,412
|
3,126
-100.0%
|
130.33
|
USD 407,412
|
|
|
2011-12-05 |
2011-12-01 |
S
Sale
|
Berrey M Michelle
Chief Medical Officer
Officer
|
3,126
-100.0%
130.33
USD 407,412
|
3,126
-100.0%
|
130.33
|
USD 407,412
|
|
|
2011-11-07 |
2011-11-01 |
S
Sale
|
OTTO MICHAEL J.
Chief Scientific Officer
Officer
|
17,500
-100.0%
74.56
USD 1,304,800
|
17,500
-100.0%
|
74.56
|
USD 1,304,800
|
|
|
2011-11-03 |
2011-11-01 |
S
Sale
|
Berrey M Michelle
Chief Medical Officer
Officer
|
3,124
-100.0%
74.56
USD 232,925
|
3,124
-100.0%
|
74.56
|
USD 232,925
|
|
|
2011-10-05 |
2011-10-03 |
S
Sale
|
Price P Schaefer
President & CEO
Executive Director
|
40,000
-5.0%
79.33
USD 3,173,316
|
40,000
-5.0%
|
79.33
|
USD 3,173,316
|
|
|
2011-09-06 |
2011-09-01 |
S
Sale
|
Price P Schaefer
President and CEO
Executive Director
|
40,000
-5.0%
65.63
USD 2,625,032
|
40,000
-5.0%
|
65.63
|
USD 2,625,032
|
|
|
2011-09-06 |
2011-09-01 |
S
Sale
|
Berrey M Michelle
Chief Medical Officer
Officer
|
3,124
-100.0%
65.63
USD 205,015
|
3,124
-100.0%
|
65.63
|
USD 205,015
|
|
|
2011-08-03 |
2011-08-01 |
S
Sale
|
Price P Schaefer
President and CEO
Executive Director
|
20,000
-5.0%
120.15
USD 2,403,006
|
20,000
-5.0%
|
120.15
|
USD 2,403,006
|
|
|
2011-08-03 |
2011-08-01 |
S
Sale
|
OTTO MICHAEL J.
Chief Scientific Officer
Officer
|
8,929
-55.4%
119.99
USD 1,071,391
|
8,929
-55.4%
|
119.99
|
USD 1,071,391
|
|
|
2011-08-03 |
2011-08-01 |
S
Sale
|
Berrey M Michelle
Chief Medical Officer
Officer
|
937
-100.0%
119.99
USD 112,431
|
937
-100.0%
|
119.99
|
USD 112,431
|
|
|
2011-07-05 |
2011-07-01 |
S
Sale
|
Price P Schaefer
President and CEO
Executive Director
|
20,000
-5.0%
110.47
USD 2,209,326
|
20,000
-5.0%
|
110.47
|
USD 2,209,326
|
|
|
2011-07-05 |
2011-07-01 |
S
Sale
|
Berrey M Michelle
Chief Medical Officer
Officer
|
938
-100.0%
111.83
USD 104,897
|
938
-100.0%
|
111.83
|
USD 104,897
|
|
|
2011-06-03 |
2011-06-01 |
S
Sale
|
Price P Schaefer
President and CEO
Executive Director
|
20,000
-5.0%
100.54
USD 2,010,706
|
20,000
-5.0%
|
100.54
|
USD 2,010,706
|
|
|
2011-05-11 |
2011-05-09 |
S
Sale
|
Rogers Michael D.
Chief Development Officer
Officer
|
10,000
-100.0%
109.08
USD 1,090,800
|
10,000
-100.0%
|
109.08
|
USD 1,090,800
|
|
|
2011-05-10 |
2011-05-06 |
S
Sale
|
Williamson Robert F III
Non-Executive Director
|
31,666
-91.3%
104.36
USD 3,304,607
|
31,666
-91.3%
|
104.36
|
USD 3,304,607
|
|
|
2011-05-10 |
2011-05-06 |
S
Sale
|
LEUTZINGER KURT
Chief Financial Officer
Officer
|
11,287
-5.7%
102.88
USD 1,161,207
|
11,287
-5.7%
|
102.88
|
USD 1,161,207
|
|
|
2011-05-09 |
2011-05-05 |
S
Sale
|
LEUTZINGER KURT
Chief Financial Officer
Officer
|
9,546
-4.6%
102.61
USD 979,515
|
9,546
-4.6%
|
102.61
|
USD 979,515
|
|
|
2011-05-05 |
2011-05-03 |
S
Sale
|
CONRAD HERBERT J
Non-Executive Director
|
40,000
-83.3%
99.04
USD 3,961,584
|
40,000
-83.3%
|
99.04
|
USD 3,961,584
|
|
|
2011-04-29 |
2011-04-28 |
S
Sale
|
OTTO MICHAEL J.
Chief Scientific Officer
Officer
|
9,500
-56.9%
99.85
USD 948,575
|
9,500
-56.9%
|
99.85
|
USD 948,575
|
|
|
2011-04-29 |
2011-04-27 |
S
Sale
|
Rogers Michael D.
Chief Development Officer
Officer
|
20,000
-100.0%
99.00
USD 1,980,068
|
20,000
-100.0%
|
99.00
|
USD 1,980,068
|
|
|
2011-04-29 |
2011-04-27 |
S
Sale
|
Berrey M Michelle
Chief Medical Officer
Officer
|
9,375
-100.0%
100.60
USD 943,125
|
9,375
-100.0%
|
100.60
|
USD 943,125
|
|
|
2011-04-29 |
2011-04-27 |
S
Sale
|
Berrey M Michelle
Chief Medical Officer
Officer
|
8,437
-100.0%
100.60
USD 848,762
|
8,437
-100.0%
|
100.60
|
USD 848,762
|
|
|
2011-04-29 |
2011-04-27 |
S
Sale
|
Berrey M Michelle
Chief Medical Officer
Officer
|
21,875
-100.0%
100.60
USD 2,200,625
|
21,875
-100.0%
|
100.60
|
USD 2,200,625
|
|
|
2011-04-29 |
2011-04-27 |
S
Sale
|
Berrey M Michelle
Chief Medical Officer
Officer
|
10,416
-100.0%
100.60
USD 1,047,850
|
10,416
-100.0%
|
100.60
|
USD 1,047,850
|
|
|
2011-03-24 |
2011-03-22 |
S
Sale
|
OTTO MICHAEL J.
Chief Scientific Officer
Officer
|
6,279
-27.3%
64.00
USD 401,856
|
6,279
-27.3%
|
64.00
|
USD 401,856
|
|
|
2010-10-01 |
2010-10-01 |
S
Sale
|
OTTO MICHAEL J.
Chief Scientific Officer
Officer
|
5,000
-23.1%
29.50
USD 147,500
|
5,000
-23.1%
|
29.50
|
USD 147,500
|
|
|
2010-09-29 |
2010-09-28 |
S
Sale
|
OTTO MICHAEL J.
Chief Scientific Officer
Officer
|
12,811
-37.1%
29.50
USD 377,925
|
12,811
-37.1%
|
29.50
|
USD 377,925
|
|
|
2010-06-18 |
2010-06-17 |
S
Sale
|
Berrey M Michelle
Chief Medical Officer
Officer
|
2,976
-100.0%
32.53
USD 96,807
|
2,976
-100.0%
|
32.53
|
USD 96,807
|
|
|
2009-09-24 |
2009-09-24 |
S
Sale
|
QVT Associates GP LLC
Large shareholder
|
400,000
-12.5%
20.88
USD 8,352,000
|
400,000
-12.5%
|
20.88
|
USD 8,352,000
|
|
|
2009-09-24 |
2009-09-24 |
S
Sale
|
QVT Associates GP LLC
Large shareholder
|
400,000
-11.1%
20.88
USD 8,352,000
|
400,000
-11.1%
|
20.88
|
USD 8,352,000
|
|
|
2009-09-24 |
2009-09-23 |
S
Sale
|
QVT Associates GP LLC
Large shareholder
|
10,000
-0.3%
22.41
USD 224,100
|
10,000
-0.3%
|
22.41
|
USD 224,100
|
|
|
2009-09-24 |
2009-09-22 |
S
Sale
|
QVT Associates GP LLC
Large shareholder
|
100,000
-2.7%
22.95
USD 2,295,000
|
100,000
-2.7%
|
22.95
|
USD 2,295,000
|
|
|
2009-09-21 |
2009-09-18 |
S
Sale
|
OTTO MICHAEL
Exec.VP,Pharm.Research
Officer
|
4,600
-19.1%
21.97
USD 101,062
|
4,600
-19.1%
|
21.97
|
USD 101,062
|
|
|
2009-09-21 |
2009-09-18 |
S
Sale
|
OTTO MICHAEL
Exec.VP,Pharm.Research
Officer
|
4,500
-65.1%
21.95
USD 98,775
|
4,500
-65.1%
|
21.95
|
USD 98,775
|
|
|
2009-09-21 |
2009-09-18 |
S
Sale
|
OTTO MICHAEL
Exec.VP,Pharm.Research
Officer
|
8,200
-22.3%
21.94
USD 179,908
|
8,200
-22.3%
|
21.94
|
USD 179,908
|
|
|
2009-09-21 |
2009-09-18 |
S
Sale
|
OTTO MICHAEL
Exec.VP,Pharm.Research
Officer
|
9,300
-20.2%
21.92
USD 203,856
|
9,300
-20.2%
|
21.92
|
USD 203,856
|
|
|
2009-09-21 |
2009-09-18 |
S
Sale
|
OTTO MICHAEL
Exec.VP,Pharm.Research
Officer
|
13,400
-22.5%
21.90
USD 293,460
|
13,400
-22.5%
|
21.90
|
USD 293,460
|
|
|
2009-03-02 |
2009-02-27 |
B
Purchase
|
INOUYE MICHAEL K
Non-Executive Director
|
200
+4.7%
10.11
USD 2,022
|
200
+4.7%
|
10.11
|
USD 2,022
|
|
|
2009-03-02 |
2009-02-27 |
B
Purchase
|
INOUYE MICHAEL K
Non-Executive Director
|
192
+4.7%
10.10
USD 1,939
|
192
+4.7%
|
10.10
|
USD 1,939
|
|
|
2009-03-02 |
2009-02-27 |
B
Purchase
|
INOUYE MICHAEL K
Non-Executive Director
|
300
+7.9%
10.09
USD 3,027
|
300
+7.9%
|
10.09
|
USD 3,027
|
|
|
2009-03-02 |
2009-02-27 |
B
Purchase
|
INOUYE MICHAEL K
Non-Executive Director
|
58
+1.5%
10.07
USD 584
|
58
+1.5%
|
10.07
|
USD 584
|
|
|
2009-03-02 |
2009-02-27 |
B
Purchase
|
INOUYE MICHAEL K
Non-Executive Director
|
500
+15.4%
10.11
USD 5,053
|
500
+15.4%
|
10.11
|
USD 5,053
|
|
|
2009-03-02 |
2009-02-26 |
B
Purchase
|
INOUYE MICHAEL K
Non-Executive Director
|
119
+3.8%
10.68
USD 1,271
|
119
+3.8%
|
10.68
|
USD 1,271
|
|
|
2009-03-02 |
2009-02-26 |
B
Purchase
|
INOUYE MICHAEL K
Non-Executive Director
|
100
+3.3%
10.67
USD 1,067
|
100
+3.3%
|
10.67
|
USD 1,067
|
|
|
2009-03-02 |
2009-02-26 |
B
Purchase
|
INOUYE MICHAEL K
Non-Executive Director
|
200
+7.1%
10.64
USD 2,128
|
200
+7.1%
|
10.64
|
USD 2,128
|
|
|
2009-03-02 |
2009-02-26 |
B
Purchase
|
INOUYE MICHAEL K
Non-Executive Director
|
300
+11.9%
10.65
USD 3,195
|
300
+11.9%
|
10.65
|
USD 3,195
|
|
|
2009-03-02 |
2009-02-26 |
B
Purchase
|
INOUYE MICHAEL K
Non-Executive Director
|
300
+13.4%
10.63
USD 3,189
|
300
+13.4%
|
10.63
|
USD 3,189
|
|
|
2009-03-02 |
2009-02-26 |
B
Purchase
|
INOUYE MICHAEL K
Non-Executive Director
|
131
+6.2%
10.60
USD 1,389
|
131
+6.2%
|
10.60
|
USD 1,389
|
|
|
2009-03-02 |
2009-02-26 |
B
Purchase
|
INOUYE MICHAEL K
Non-Executive Director
|
100
+5.0%
10.59
USD 1,059
|
100
+5.0%
|
10.59
|
USD 1,059
|
|
|
2009-02-26 |
2009-02-25 |
B
Purchase
|
LUBETKIN PAUL
Executive VP & General Counsel
Officer
|
125
+33.3%
10.14
USD 1,268
|
125
+33.3%
|
10.14
|
USD 1,268
|
|
|
2009-02-26 |
2009-02-25 |
B
Purchase
|
LUBETKIN PAUL
Executive VP & General Counsel
Officer
|
175
+87.5%
10.65
USD 1,864
|
175
+87.5%
|
10.65
|
USD 1,864
|
|
|
2009-02-26 |
2009-02-25 |
B
Purchase
|
LUBETKIN PAUL
Executive VP & General Counsel
Officer
|
200
+inf%
10.64
USD 2,128
|
200
+inf%
|
10.64
|
USD 2,128
|
|
|
2008-11-17 |
2008-11-13 |
S
Sale
|
Rogers Michael D.
Chief Development Officer
Officer
|
600
-100.0%
18.75
USD 11,250
|
600
-100.0%
|
18.75
|
USD 11,250
|
|
|
2008-11-17 |
2008-11-13 |
S
Sale
|
Rogers Michael D.
Chief Development Officer
Officer
|
1
-0.2%
18.72
USD 19
|
1
-0.2%
|
18.72
|
USD 19
|
|
|
2008-11-17 |
2008-11-13 |
S
Sale
|
Rogers Michael D.
Chief Development Officer
Officer
|
300
-33.3%
18.71
USD 5,613
|
300
-33.3%
|
18.71
|
USD 5,613
|
|
|
2008-11-17 |
2008-11-13 |
S
Sale
|
Rogers Michael D.
Chief Development Officer
Officer
|
300
-25.0%
18.70
USD 5,610
|
300
-25.0%
|
18.70
|
USD 5,610
|
|
|
2008-11-17 |
2008-11-13 |
S
Sale
|
Rogers Michael D.
Chief Development Officer
Officer
|
499
-29.4%
18.69
USD 9,326
|
499
-29.4%
|
18.69
|
USD 9,326
|
|
|
2008-11-17 |
2008-11-13 |
S
Sale
|
Rogers Michael D.
Chief Development Officer
Officer
|
701
-29.2%
18.65
USD 13,074
|
701
-29.2%
|
18.65
|
USD 13,074
|
|
|
2008-11-17 |
2008-11-13 |
S
Sale
|
Rogers Michael D.
Chief Development Officer
Officer
|
100
-4.0%
18.63
USD 1,863
|
100
-4.0%
|
18.63
|
USD 1,863
|
|
|
2008-11-17 |
2008-11-13 |
S
Sale
|
Rogers Michael D.
Chief Development Officer
Officer
|
100
-3.3%
18.59
USD 1,859
|
100
-3.3%
|
18.59
|
USD 1,859
|
|
|
2008-11-17 |
2008-11-13 |
S
Sale
|
Rogers Michael D.
Chief Development Officer
Officer
|
200
-6.2%
18.58
USD 3,716
|
200
-6.2%
|
18.58
|
USD 3,716
|
|
|
2008-11-17 |
2008-11-13 |
S
Sale
|
Rogers Michael D.
Chief Development Officer
Officer
|
99
-3.0%
18.55
USD 1,836
|
99
-3.0%
|
18.55
|
USD 1,836
|
|
|
2008-11-17 |
2008-11-13 |
S
Sale
|
Rogers Michael D.
Chief Development Officer
Officer
|
600
-15.4%
18.50
USD 11,100
|
600
-15.4%
|
18.50
|
USD 11,100
|
|
|
2008-11-17 |
2008-11-13 |
S
Sale
|
Rogers Michael D.
Chief Development Officer
Officer
|
300
-7.1%
18.43
USD 5,529
|
300
-7.1%
|
18.43
|
USD 5,529
|
|
|
2008-11-17 |
2008-11-13 |
S
Sale
|
Rogers Michael D.
Chief Development Officer
Officer
|
300
-6.7%
18.40
USD 5,520
|
300
-6.7%
|
18.40
|
USD 5,520
|
|
|
2008-11-17 |
2008-11-13 |
S
Sale
|
Rogers Michael D.
Chief Development Officer
Officer
|
70
-1.5%
18.39
USD 1,287
|
70
-1.5%
|
18.39
|
USD 1,287
|
|
|
2008-11-17 |
2008-11-13 |
S
Sale
|
Rogers Michael D.
Chief Development Officer
Officer
|
100
-2.1%
18.38
USD 1,838
|
100
-2.1%
|
18.38
|
USD 1,838
|
|
|
2008-11-17 |
2008-11-13 |
S
Sale
|
Rogers Michael D.
Chief Development Officer
Officer
|
100
-2.1%
18.37
USD 1,837
|
100
-2.1%
|
18.37
|
USD 1,837
|
|
|
2008-11-17 |
2008-11-13 |
S
Sale
|
Rogers Michael D.
Chief Development Officer
Officer
|
1,430
-23.1%
18.35
USD 26,241
|
1,430
-23.1%
|
18.35
|
USD 26,241
|
|
|
2008-11-17 |
2008-11-13 |
S
Sale
|
Rogers Michael D.
Chief Development Officer
Officer
|
400
-6.1%
18.32
USD 7,328
|
400
-6.1%
|
18.32
|
USD 7,328
|
|
|
2008-11-17 |
2008-11-13 |
S
Sale
|
Rogers Michael D.
Chief Development Officer
Officer
|
300
-4.3%
18.29
USD 5,487
|
300
-4.3%
|
18.29
|
USD 5,487
|
|
|
2008-11-17 |
2008-11-13 |
S
Sale
|
Rogers Michael D.
Chief Development Officer
Officer
|
400
-5.5%
18.27
USD 7,308
|
400
-5.5%
|
18.27
|
USD 7,308
|
|
|
2008-11-17 |
2008-11-13 |
S
Sale
|
Rogers Michael D.
Chief Development Officer
Officer
|
400
-5.2%
18.26
USD 7,304
|
400
-5.2%
|
18.26
|
USD 7,304
|
|
|
2008-11-17 |
2008-11-13 |
S
Sale
|
Rogers Michael D.
Chief Development Officer
Officer
|
1,672
-17.8%
18.25
USD 30,514
|
1,672
-17.8%
|
18.25
|
USD 30,514
|
|
|
2008-11-17 |
2008-11-13 |
S
Sale
|
Rogers Michael D.
Chief Development Officer
Officer
|
600
-6.0%
18.24
USD 10,944
|
600
-6.0%
|
18.24
|
USD 10,944
|
|
