|
2023-11-02 |
2023-11-02 |
B
Purchase
|
KAYNE RICHARD A
Large shareholder
|
23,398
+0.4%
0.30
USD 6,966
|
23,398
+0.4%
|
0.30
|
USD 6,966
|
|
|
2023-11-02 |
2023-11-01 |
B
Purchase
|
KAYNE RICHARD A
Large shareholder
|
100,000
+1.9%
0.28
USD 27,970
|
100,000
+1.9%
|
0.28
|
USD 27,970
|
|
|
2023-11-02 |
2023-10-31 |
B
Purchase
|
KAWAS LEEN
Large shareholder
|
12,345
+0.3%
0.26
USD 3,228
|
12,345
+0.3%
|
0.26
|
USD 3,228
|
|
|
2023-11-02 |
2023-10-31 |
B
Purchase
|
KAWAS LEEN
Large shareholder
|
11,987
+0.3%
0.26
USD 3,147
|
11,987
+0.3%
|
0.26
|
USD 3,147
|
|
|
2023-11-02 |
2023-10-31 |
B
Purchase
|
KAYNE RICHARD A
Large shareholder
|
130,509
+2.5%
0.24
USD 31,505
|
130,509
+2.5%
|
0.24
|
USD 31,505
|
|
|
2023-11-02 |
2023-10-31 |
B
Purchase
|
KAYNE RICHARD A
Large shareholder
|
12,345
+0.2%
0.26
USD 3,228
|
12,345
+0.2%
|
0.26
|
USD 3,228
|
|
|
2023-11-02 |
2023-10-31 |
B
Purchase
|
KAYNE RICHARD A
Large shareholder
|
11,987
+0.2%
0.26
USD 3,147
|
11,987
+0.2%
|
0.26
|
USD 3,147
|
|
|
2023-03-21 |
2023-03-17 |
S
Sale
|
Mayer Eldon C. III
Ex VP & Chief Commerc. Officer
Officer
|
1,875
-3.2%
1.07
USD 2,008
|
1,875
-3.2%
|
1.07
|
USD 2,008
|
|
|
2023-03-21 |
2023-03-17 |
S
Sale
|
Mayer Eldon C. III
Ex VP & Chief Commerc. Officer
Officer
|
2,520
-4.2%
1.07
USD 2,696
|
2,520
-4.2%
|
1.07
|
USD 2,696
|
|
|
2023-01-25 |
2023-01-23 |
B
Purchase
|
Dietz Thomas John
Non-Executive Director
|
50,000
+inf%
1.43
USD 71,580
|
50,000
+inf%
|
1.43
|
USD 71,580
|
|
|
2023-01-03 |
2022-12-29 |
S
Sale
|
Murray Christine
Non-Executive Director
|
5,000
-31.2%
1.22
USD 6,104
|
5,000
-31.2%
|
1.22
|
USD 6,104
|
|
|
2022-12-27 |
2022-12-22 |
B
Purchase
|
Glenn Jeffrey S
Non-Executive Director
|
100,000
+121.4%
1.28
USD 127,950
|
100,000
+121.4%
|
1.28
|
USD 127,950
|
|
|
2022-12-27 |
2022-12-22 |
S
Sale
|
Dietz Thomas John
Non-Executive Director
|
22,500
-51.7%
1.17
USD 26,303
|
22,500
-51.7%
|
1.17
|
USD 26,303
|
|
|
2022-08-18 |
2022-08-16 |
PS
Planned sale
|
Apelian David
Non-Executive Director
|
5,000
-31.2%
9.81
USD 49,031
|
5,000
-31.2%
|
9.81
|
USD 49,031
|
|
|
2022-03-14 |
2022-03-14 |
S
Sale
|
Mayer Eldon C. III
Ex VP & Chief Commerc. Officer
Officer
|
1,657
-2.7%
5.60
USD 9,275
|
1,657
-2.7%
|
5.60
|
USD 9,275
|
|
|
2022-03-14 |
2022-03-14 |
S
Sale
|
Ryali Sriram
Chief Financial Officer
Officer
|
2,266
-5.2%
5.60
USD 12,683
|
2,266
-5.2%
|
5.60
|
USD 12,683
|
|
|
2022-01-11 |
2022-01-07 |
S
Sale
|
Mayer Eldon C. III
Ex VP & Chief Commerc. Officer
Officer
|
1,560
-3.3%
4.95
USD 7,722
|
1,560
-3.3%
|
4.95
|
USD 7,722
|
|
|
2021-03-15 |
2021-03-15 |
S
Sale
|
Loh Evan
Non-Executive Director
|
2,000
-20.0%
10.14
USD 20,280
|
2,000
-20.0%
|
10.14
|
USD 20,280
|
|
|
2021-01-11 |
2021-01-08 |
S
Sale
|
Mayer Eldon C. III
Ex VP & Chief Commerc. Officer
Officer
|
1,690
-4.5%
11.68
USD 19,739
|
1,690
-4.5%
|
11.68
|
USD 19,739
|
|
|
2020-08-12 |
2020-08-12 |
B
Purchase
|
Glenn Jeffrey S
Non-Executive Director
|
4,500
+900.0%
11.44
USD 51,465
|
4,500
+900.0%
|
11.44
|
USD 51,465
|
|
|
2020-08-12 |
2020-08-12 |
B
Purchase
|
Glenn Jeffrey S
Non-Executive Director
|
500
+inf%
11.28
USD 5,638
|
500
+inf%
|
11.28
|
USD 5,638
|
|
|
2020-08-12 |
2020-08-11 |
B
Purchase
|
Glenn Jeffrey S
Non-Executive Director
|
5,000
+7.5%
11.49
USD 57,464
|
5,000
+7.5%
|
11.49
|
USD 57,464
|
|
|
2020-03-17 |
2020-03-16 |
B
Purchase
|
Glenn Jeffrey S
Non-Executive Director
|
30,000
+82.5%
5.03
USD 150,813
|
30,000
+82.5%
|
5.03
|
USD 150,813
|
|
|
2020-03-17 |
2020-03-16 |
B
Purchase
|
Dietz Thomas John
Non-Executive Director
|
1,000
+3.4%
4.95
USD 4,950
|
1,000
+3.4%
|
4.95
|
USD 4,950
|
|
|
2020-01-30 |
2020-01-24 |
B
Purchase
|
Mayer Eldon C. III
Ex VP & Chief Commerc. Officer
|
5,000
+20.0%
13.52
USD 67,603
|
5,000
+20.0%
|
13.52
|
USD 67,603
|
|
|
2020-01-13 |
2020-01-10 |
B
Purchase
|
Dietz Thomas John
|
4,000
+20.0%
13.94
USD 55,760
|
4,000
+20.0%
|
13.94
|
USD 55,760
|
|
|
2019-04-23 |
2019-04-23 |
B
Purchase
|
Dietz Thomas John
|
5,000
+33.3%
11.10
USD 55,495
|
5,000
+33.3%
|
11.10
|
USD 55,495
|
|
|
2019-04-22 |
2019-04-22 |
B
Purchase
|
Patton Stephana Eilene
See Remarks
|
1,000
+33.3%
11.03
USD 11,030
|
1,000
+33.3%
|
11.03
|
USD 11,030
|
|
|
2019-04-22 |
2019-04-22 |
B
Purchase
|
Ryali Sriram
Chief Financial Officer
|
1,250
+inf%
11.08
USD 13,853
|
1,250
+inf%
|
11.08
|
USD 13,853
|
|
|
2019-04-22 |
2019-04-22 |
B
Purchase
|
Dietz Thomas John
|
5,000
+50.0%
11.05
USD 55,250
|
5,000
+50.0%
|
11.05
|
USD 55,250
|
|
|
2019-04-26 |
2019-02-04 |
B
Purchase
|
Cory David A
President and CEO
Executive Director
|
343
+0.5%
11.26
USD 3,862
|
343
+0.5%
|
11.26
|
USD 3,862
|
|
|
2019-02-06 |
2019-02-04 |
B
Purchase
|
Cory David A
President and CEO
Executive Director
|
227
+0.4%
14.13
USD 3,208
|
227
+0.4%
|
14.13
|
USD 3,208
|
|
|
2018-12-20 |
2018-12-20 |
B
Purchase
|
Dietz Thomas John
Non-Executive Director
|
5,000
+100.0%
9.98
USD 49,900
|
5,000
+100.0%
|
9.98
|
USD 49,900
|
|
|
2018-12-10 |
2018-12-06 |
B
Purchase
|
Dietz Thomas John
Non-Executive Director
|
5,000
+inf%
11.26
USD 56,300
|
5,000
+inf%
|
11.26
|
USD 56,300
|
|
|
2018-11-30 |
2018-11-29 |
B
Purchase
|
Mayer Eldon C. III
Non-Executive Director
|
4,000
+19.0%
10.21
USD 40,840
|
4,000
+19.0%
|
10.21
|
USD 40,840
|
|
|
2018-11-28 |
2018-11-27 |
B
Purchase
|
Mayer Eldon C. III
Non-Executive Director
|
7,500
+100.0%
9.92
USD 74,408
|
7,500
+100.0%
|
9.92
|
USD 74,408
|
|
|
2018-11-28 |
2018-11-26 |
B
Purchase
|
Mayer Eldon C. III
Non-Executive Director
|
7,500
+inf%
9.75
USD 73,143
|
7,500
+inf%
|
9.75
|
USD 73,143
|
|
|
2018-10-22 |
2018-10-18 |
S
Sale
|
INTERWEST PARTNERS X LP
Large shareholder
|
26,465
-1.9%
12.00
USD 317,606
|
26,465
-1.9%
|
12.00
|
USD 317,606
|
|
|
2018-10-22 |
2018-10-18 |
S
Sale
|
INTERWEST PARTNERS X LP
Large shareholder
|
210,800
-13.2%
12.07
USD 2,544,714
|
210,800
-13.2%
|
12.07
|
USD 2,544,714
|
|
|
2018-04-04 |
2018-04-02 |
S
Sale
|
Quan Joanne
Chief Medical Officer
|
4,000
-100.0%
10.00
USD 40,000
|
4,000
-100.0%
|
10.00
|
USD 40,000
|
|
|
2017-09-05 |
2017-09-01 |
B
Purchase
|
Glenn Jeffrey S
|
15,000
+91.7%
9.53
USD 142,950
|
15,000
+91.7%
|
9.53
|
USD 142,950
|
|
|
2016-11-21 |
2016-11-18 |
B
Purchase
|
Glenn Jeffrey S
Non-Executive Director
|
460
+inf%
12.90
USD 5,934
|
460
+inf%
|
12.90
|
USD 5,934
|
|
|
2016-11-21 |
2016-11-17 |
B
Purchase
|
Glenn Jeffrey S
Non-Executive Director
|
15,000
+1107.0%
12.73
USD 190,950
|
15,000
+1107.0%
|
12.73
|
USD 190,950
|
|
|
2016-08-22 |
2016-08-18 |
B
Purchase
|
Vivo Ventures VI, LLC
Large shareholder
|
1,364
+11.7%
16.00
USD 21,824
|
1,364
+11.7%
|
16.00
|
USD 21,824
|
|
|
2016-08-22 |
2016-08-18 |
B
Purchase
|
Vivo Ventures VI, LLC
Large shareholder
|
186,136
+11.7%
16.00
USD 2,978,176
|
186,136
+11.7%
|
16.00
|
USD 2,978,176
|
|
|
2016-08-19 |
2016-08-18 |
B
Purchase
|
Cory David A
President and CEO
Executive Director
|
1,562
+2.7%
15.70
USD 24,523
|
1,562
+2.7%
|
15.70
|
USD 24,523
|
|
|
2016-08-19 |
2016-08-18 |
B
Purchase
|
Shaffer James P
Chief Business Officer
Officer
|
3,125
+125.3%
15.70
USD 49,063
|
3,125
+125.3%
|
15.70
|
USD 49,063
|
|
|
2016-06-22 |
2016-06-22 |
B
Purchase
|
WELCH JAMES H
Chief Financial Officer
Officer
|
500
+25.0%
19.79
USD 9,897
|
500
+25.0%
|
19.79
|
USD 9,897
|
|
|
2016-06-22 |
2016-06-20 |
B
Purchase
|
WELCH JAMES H
Chief Financial Officer
Officer
|
2,000
+inf%
19.80
USD 39,592
|
2,000
+inf%
|
19.80
|
USD 39,592
|
|
|
2016-06-14 |
2016-06-13 |
B
Purchase
|
Shaffer James P
Chief Business Officer
Officer
|
420
+20.2%
22.20
USD 9,324
|
420
+20.2%
|
22.20
|
USD 9,324
|
|
|
2016-06-14 |
2016-06-13 |
B
Purchase
|
Shaffer James P
Chief Business Officer
Officer
|
100
+5.1%
22.17
USD 2,217
|
100
+5.1%
|
22.17
|
USD 2,217
|
|
|
2016-06-14 |
2016-06-13 |
B
Purchase
|
Shaffer James P
Chief Business Officer
Officer
|
730
+58.6%
22.16
USD 16,177
|
730
+58.6%
|
22.16
|
USD 16,177
|
|
|
2016-05-23 |
2016-05-23 |
B
Purchase
|
Shaffer James P
Chief Business Officer
Officer
|
745
+149.0%
19.99
USD 14,893
|
745
+149.0%
|
19.99
|
USD 14,893
|
|
|
2016-05-23 |
2016-05-19 |
B
Purchase
|
Shaffer James P
Chief Business Officer
Officer
|
500
+inf%
19.52
USD 9,760
|
500
+inf%
|
19.52
|
USD 9,760
|
|
|
2015-04-07 |
2015-04-06 |
PS
Planned sale
|
ZSEBO KRISZTINA M
Chief Executive Officer
Executive Director
|
6,629
-68.0%
18.44
USD 122,239
|
6,629
-68.0%
|
18.44
|
USD 122,239
|
|
|
2015-04-07 |
2015-04-06 |
PS
Planned sale
|
ZSEBO KRISZTINA M
Chief Executive Officer
Executive Director
|
41,302
-80.9%
18.16
USD 750,044
|
41,302
-80.9%
|
18.16
|
USD 750,044
|
|
|
2015-04-03 |
2015-04-02 |
PS
Planned sale
|
LABA REBECQUE J
VP, Corporate Operations
Officer
|
1,012
-25.9%
16.95
USD 17,153
|
1,012
-25.9%
|
16.95
|
USD 17,153
|
|
|
2015-04-03 |
2015-04-02 |
PS
Planned sale
|
LABA REBECQUE J
VP, Corporate Operations
Officer
|
10,000
-71.9%
17.33
USD 173,300
|
10,000
-71.9%
|
17.33
|
USD 173,300
|
|
|
2015-04-03 |
2015-04-01 |
PS
Planned sale
|
TAKEYA RYAN K
VP, Manufacturing
Officer
|
4,444
-75.6%
19.13
USD 85,014
|
4,444
-75.6%
|
19.13
|
USD 85,014
|
|
|
2015-03-09 |
2015-03-09 |
PS
Planned sale
|
ZSEBO KRISZTINA M
Chief Executive Officer
Executive Director
|
6,629
-68.0%
24.71
USD 163,803
|
6,629
-68.0%
|
24.71
|
USD 163,803
|
|
|
2015-03-09 |
2015-03-09 |
PS
Planned sale
|
ZSEBO KRISZTINA M
Chief Executive Officer
Executive Director
|
41,302
-80.9%
24.81
USD 1,024,703
|
41,302
-80.9%
|
24.81
|
USD 1,024,703
|
|
|
2015-03-09 |
2015-03-06 |
PS
Planned sale
|
Honig Peter
Non-Executive Director
|
5,000
-100.0%
25.00
USD 125,000
|
5,000
-100.0%
|
25.00
|
USD 125,000
|
|
|
2015-03-09 |
2015-03-06 |
PS
Planned sale
|
LABA REBECQUE J
VP, Corporate Operations
Officer
|
4,000
-58.0%
22.48
USD 89,920
|
4,000
-58.0%
|
22.48
|
USD 89,920
|
|
|
2015-03-09 |
2015-03-06 |
PS
Planned sale
|
LABA REBECQUE J
VP, Corporate Operations
Officer
|
10,000
-59.2%
23.29
USD 232,900
|
10,000
-59.2%
|
23.29
|
USD 232,900
|
|
|
2015-03-09 |
2015-03-05 |
PS
Planned sale
|
Honig Peter
Non-Executive Director
|
2,200
-100.0%
22.29
USD 49,038
|
2,200
-100.0%
|
22.29
|
USD 49,038
|
|
|
2015-03-09 |
2015-03-05 |
PS
Planned sale
|
Honig Peter
Non-Executive Director
|
2,500
-53.2%
22.50
USD 56,250
|
2,500
-53.2%
|
22.50
|
USD 56,250
|
|
|
2015-03-03 |
2015-03-02 |
PS
Planned sale
|
TAKEYA RYAN K
VP, Manufacturing
Officer
|
7,777
-84.4%
18.48
USD 143,719
|
7,777
-84.4%
|
18.48
|
USD 143,719
|
|
|
2015-02-10 |
2015-02-09 |
PS
Planned sale
|
ZSEBO KRISZTINA M
Chief Executive Officer
Executive Director
|
6,629
-68.0%
15.94
USD 105,666
|
6,629
-68.0%
|
15.94
|
USD 105,666
|
|
|
2015-02-10 |
2015-02-09 |
PS
Planned sale
|
ZSEBO KRISZTINA M
Chief Executive Officer
Executive Director
|
41,302
-80.9%
15.85
USD 654,637
|
41,302
-80.9%
|
15.85
|
USD 654,637
|
|
|
2015-02-10 |
2015-02-06 |
PS
Planned sale
|
LABA REBECQUE J
VP, Corporate Operations
Officer
|
4,000
-58.0%
16.08
USD 64,320
|
4,000
-58.0%
|
16.08
|
USD 64,320
|
|
|
2015-02-10 |
2015-02-06 |
PS
Planned sale
|
LABA REBECQUE J
VP, Corporate Operations
Officer
|
10,000
-59.2%
16.08
USD 160,800
|
10,000
-59.2%
|
16.08
|
USD 160,800
|
|
|
2015-02-03 |
2015-02-02 |
PS
Planned sale
|
TAKEYA RYAN K
VP, Manufacturing
Officer
|
7,777
-84.4%
16.35
USD 127,154
|
7,777
-84.4%
|
16.35
|
USD 127,154
|
|
|
2015-01-12 |
2015-01-09 |
PS
Planned sale
|
RUDY JEFFREY J
VP, Clinical Operations
Officer
|
10,000
-90.7%
18.51
USD 185,100
|
10,000
-90.7%
|
18.51
|
USD 185,100
|
|
|
2015-01-08 |
2015-01-07 |
PS
Planned sale
|
LABA REBECQUE J
VP, Corporate Operations
Officer
|
20,000
-87.4%
17.30
USD 346,000
|
20,000
-87.4%
|
17.30
|
USD 346,000
|
|
|
2015-01-08 |
2015-01-06 |
PS
Planned sale
|
ZSEBO KRISZTINA M
Chief Executive Officer
Executive Director
|
41,302
-93.0%
17.51
USD 723,198
|
41,302
-93.0%
|
17.51
|
USD 723,198
|
|
