|
2023-01-26 |
2023-01-24 |
PS
Planned sale
|
Fong James K
EVP & Chief Commercial Officer
Officer
|
100,000
-96.6%
6.00
USD 600,000
|
100,000
-96.6%
|
6.00
|
USD 600,000
|
|
|
2023-01-26 |
2023-01-24 |
PS
Planned sale
|
Craig Adam R
President and CEO
Executive Director
|
2,117
-6.7%
6.01
USD 12,723
|
2,117
-6.7%
|
6.01
|
USD 12,723
|
|
|
2023-01-26 |
2023-01-24 |
PS
Planned sale
|
Craig Adam R
President and CEO
Executive Director
|
83,200
-73.9%
6.00
USD 499,200
|
83,200
-73.9%
|
6.00
|
USD 499,200
|
|
|
2023-01-03 |
2023-01-03 |
PS
Planned sale
|
KIRSKE DAVID
EVP, Chief Financial Officer
Officer
|
27,021
-61.2%
6.01
USD 162,423
|
27,021
-61.2%
|
6.01
|
USD 162,423
|
|
|
2023-01-03 |
2023-01-03 |
PS
Planned sale
|
Craig Adam R
President and CEO
Executive Director
|
84,683
-74.2%
6.01
USD 509,224
|
84,683
-74.2%
|
6.01
|
USD 509,224
|
|
|
2023-01-03 |
2022-12-30 |
PS
Planned sale
|
KIRSKE DAVID
EVP, Chief Financial Officer
Officer
|
1,047
-5.8%
6.01
USD 6,292
|
1,047
-5.8%
|
6.01
|
USD 6,292
|
|
|
2023-01-03 |
2022-12-30 |
PS
Planned sale
|
KIRSKE DAVID
EVP, Chief Financial Officer
Officer
|
800
-4.5%
6.01
USD 4,804
|
800
-4.5%
|
6.01
|
USD 4,804
|
|
|
2023-01-03 |
2022-12-30 |
PS
Planned sale
|
KIRSKE DAVID
EVP, Chief Financial Officer
Officer
|
12,000
-41.2%
6.00
USD 72,000
|
12,000
-41.2%
|
6.00
|
USD 72,000
|
|
|
2023-01-03 |
2022-12-30 |
PS
Planned sale
|
Craig Adam R
President and CEO
Executive Director
|
4,400
-13.0%
6.01
USD 26,444
|
4,400
-13.0%
|
6.01
|
USD 26,444
|
|
|
2023-01-03 |
2022-12-30 |
PS
Planned sale
|
Craig Adam R
President and CEO
Executive Director
|
700
-2.3%
6.01
USD 4,204
|
700
-2.3%
|
6.01
|
USD 4,204
|
|
|
2023-01-03 |
2022-12-30 |
PS
Planned sale
|
Craig Adam R
President and CEO
Executive Director
|
12,000
-29.0%
6.00
USD 72,000
|
12,000
-29.0%
|
6.00
|
USD 72,000
|
|
|
2023-01-03 |
2022-12-29 |
PS
Planned sale
|
KIRSKE DAVID
EVP, Chief Financial Officer
Officer
|
13,174
-43.8%
6.00
USD 79,044
|
13,174
-43.8%
|
6.00
|
USD 79,044
|
|
|
2023-01-03 |
2022-12-29 |
PS
Planned sale
|
Craig Adam R
President and CEO
Executive Director
|
13,800
-33.1%
6.00
USD 82,800
|
13,800
-33.1%
|
6.00
|
USD 82,800
|
|
|
2022-11-14 |
2022-11-10 |
PS
Planned sale
|
Craig Adam R
President and CEO
Executive Director
|
2,700
-8.8%
6.04
USD 16,308
|
2,700
-8.8%
|
6.04
|
USD 16,308
|
|
|
2022-11-14 |
2022-11-10 |
PS
Planned sale
|
Craig Adam R
President and CEO
Executive Director
|
5,800
-16.0%
6.03
USD 34,974
|
5,800
-16.0%
|
6.03
|
USD 34,974
|
|
|
2022-11-14 |
2022-11-10 |
PS
Planned sale
|
Craig Adam R
President and CEO
Executive Director
|
16,396
-31.1%
6.02
USD 98,704
|
16,396
-31.1%
|
6.02
|
USD 98,704
|
|
|
2022-11-14 |
2022-11-10 |
PS
Planned sale
|
Craig Adam R
President and CEO
Executive Director
|
100
-0.2%
6.02
USD 602
|
100
-0.2%
|
6.02
|
USD 602
|
|
|
2022-11-14 |
2022-11-10 |
PS
Planned sale
|
Craig Adam R
President and CEO
Executive Director
|
26,700
-33.6%
6.01
USD 160,467
|
26,700
-33.6%
|
6.01
|
USD 160,467
|
|
|
2022-11-14 |
2022-11-10 |
PS
Planned sale
|
Craig Adam R
President and CEO
Executive Director
|
200
-0.3%
6.01
USD 1,201
|
200
-0.3%
|
6.01
|
USD 1,201
|
|
|
2022-11-14 |
2022-11-10 |
PS
Planned sale
|
Craig Adam R
President and CEO
Executive Director
|
136,408
-63.1%
6.00
USD 818,448
|
136,408
-63.1%
|
6.00
|
USD 818,448
|
|
|
2022-11-14 |
2022-11-09 |
PS
Planned sale
|
Craig Adam R
President and CEO
Executive Director
|
300
-1.1%
6.02
USD 1,805
|
300
-1.1%
|
6.02
|
USD 1,805
|
|
|
2022-11-14 |
2022-11-09 |
PS
Planned sale
|
Craig Adam R
President and CEO
Executive Director
|
7,596
-21.2%
6.01
USD 45,652
|
7,596
-21.2%
|
6.01
|
USD 45,652
|
|
|
2022-11-14 |
2022-11-09 |
PS
Planned sale
|
Craig Adam R
President and CEO
Executive Director
|
46,100
-56.3%
6.00
USD 276,600
|
46,100
-56.3%
|
6.00
|
USD 276,600
|
|
|
2022-11-10 |
2022-11-08 |
PS
Planned sale
|
Metzger Michael A
Non-Executive Director
|
4,500
-100.0%
5.70
USD 25,660
|
4,500
-100.0%
|
5.70
|
USD 25,660
|
|
|
2022-11-10 |
2022-11-08 |
PS
Planned sale
|
Metzger Michael A
Non-Executive Director
|
36,942
-89.1%
5.65
USD 208,578
|
36,942
-89.1%
|
5.65
|
USD 208,578
|
|
|
2022-11-10 |
2022-11-08 |
PS
Planned sale
|
Metzger Michael A
Non-Executive Director
|
50,058
-54.7%
5.53
USD 276,781
|
50,058
-54.7%
|
5.53
|
USD 276,781
|
|
|
2022-10-06 |
2022-10-04 |
PS
Planned sale
|
KIRSKE DAVID
EVP, Chief Financial Officer
Officer
|
609
-3.5%
6.27
USD 3,818
|
609
-3.5%
|
6.27
|
USD 3,818
|
|
|
2022-10-06 |
2022-10-04 |
PS
Planned sale
|
KIRSKE DAVID
EVP, Chief Financial Officer
Officer
|
100
-0.6%
6.26
USD 626
|
100
-0.6%
|
6.26
|
USD 626
|
|
|
2022-10-06 |
2022-10-04 |
PS
Planned sale
|
KIRSKE DAVID
EVP, Chief Financial Officer
Officer
|
1,400
-7.6%
6.25
USD 8,750
|
1,400
-7.6%
|
6.25
|
USD 8,750
|
|
|
2022-10-03 |
2022-10-03 |
PS
Planned sale
|
KIRSKE DAVID
EVP, Chief Financial Officer
Officer
|
300
-1.7%
6.25
USD 1,875
|
300
-1.7%
|
6.25
|
USD 1,875
|
|
|
2022-10-03 |
2022-09-30 |
PS
Planned sale
|
KIRSKE DAVID
EVP, Chief Financial Officer
Officer
|
139,841
-89.2%
6.05
USD 845,549
|
139,841
-89.2%
|
6.05
|
USD 845,549
|
|
|
2022-10-03 |
2022-09-29 |
PS
Planned sale
|
KIRSKE DAVID
EVP, Chief Financial Officer
Officer
|
100
-0.6%
6.01
USD 601
|
100
-0.6%
|
6.01
|
USD 601
|
|
|
2022-10-03 |
2022-09-29 |
PS
Planned sale
|
KIRSKE DAVID
EVP, Chief Financial Officer
Officer
|
800
-4.5%
6.00
USD 4,800
|
800
-4.5%
|
6.00
|
USD 4,800
|
|
|
2022-09-20 |
2022-09-16 |
PS
Planned sale
|
KIRSKE DAVID
EVP, Chief Financial Officer
Officer
|
22,592
-57.2%
6.02
USD 136,004
|
22,592
-57.2%
|
6.02
|
USD 136,004
|
|
|
2022-09-14 |
2022-09-12 |
PS
Planned sale
|
Craig Adam R
President and CEO
Executive Director
|
242,300
-89.7%
6.43
USD 1,557,989
|
242,300
-89.7%
|
6.43
|
USD 1,557,989
|
|
|
2022-08-16 |
2022-08-16 |
B
Purchase
|
Craig Adam R
President and CEO
Executive Director
|
5,000
+21.9%
5.50
USD 27,500
|
5,000
+21.9%
|
5.50
|
USD 27,500
|
|
|
2022-08-11 |
2022-08-09 |
S
Sale
|
BVF PARTNERS L P/IL
Non-Executive Director
Large shareholder
|
1,289,434
-99.5%
6.12
USD 7,891,336
|
1,289,434
-99.5%
|
6.12
|
USD 7,891,336
|
|
|
2022-08-11 |
2022-08-09 |
S
Sale
|
BVF PARTNERS L P/IL
Non-Executive Director
Large shareholder
|
469,040
-95.9%
6.12
USD 2,870,525
|
469,040
-95.9%
|
6.12
|
USD 2,870,525
|
|
|
2022-08-11 |
2022-08-09 |
S
Sale
|
BVF PARTNERS L P/IL
Non-Executive Director
Large shareholder
|
2,890,723
-94.5%
6.12
USD 17,691,225
|
2,890,723
-94.5%
|
6.12
|
USD 17,691,225
|
|
|
2022-08-11 |
2022-08-09 |
S
Sale
|
BVF PARTNERS L P/IL
Non-Executive Director
Large shareholder
|
3,850,803
-94.2%
6.12
USD 23,566,914
|
3,850,803
-94.2%
|
6.12
|
USD 23,566,914
|
|
|
2022-07-11 |
2022-07-07 |
PS
Planned sale
|
Metzger Michael A
Non-Executive Director
|
1,100
-100.0%
6.55
USD 7,205
|
1,100
-100.0%
|
6.55
|
USD 7,205
|
|
|
2022-07-11 |
2022-07-07 |
PS
Planned sale
|
Metzger Michael A
Non-Executive Director
|
400
-26.7%
6.54
USD 2,616
|
400
-26.7%
|
6.54
|
USD 2,616
|
|
|
2022-07-11 |
2022-07-07 |
PS
Planned sale
|
Metzger Michael A
Non-Executive Director
|
400
-21.1%
6.53
USD 2,612
|
400
-21.1%
|
6.53
|
USD 2,612
|
|
|
2022-07-11 |
2022-07-07 |
PS
Planned sale
|
Metzger Michael A
Non-Executive Director
|
3,321
-63.6%
6.52
USD 21,653
|
3,321
-63.6%
|
6.52
|
USD 21,653
|
|
|
2022-07-11 |
2022-07-07 |
PS
Planned sale
|
Metzger Michael A
Non-Executive Director
|
5,900
-53.1%
6.51
USD 38,409
|
5,900
-53.1%
|
6.51
|
USD 38,409
|
|
|
2022-07-11 |
2022-07-07 |
PS
Planned sale
|
Metzger Michael A
Non-Executive Director
|
9,000
-44.7%
6.50
USD 58,500
|
9,000
-44.7%
|
6.50
|
USD 58,500
|
|
|
2022-07-06 |
2022-07-06 |
PS
Planned sale
|
Craig Adam R
President and CEO
Executive Director
|
18,223
-44.4%
6.11
USD 111,343
|
18,223
-44.4%
|
6.11
|
USD 111,343
|
|
|
2022-07-07 |
2022-07-05 |
PS
Planned sale
|
Metzger Michael A
Non-Executive Director
|
3,331
-14.2%
6.23
USD 20,737
|
3,331
-14.2%
|
6.23
|
USD 20,737
|
|
|
2022-07-07 |
2022-07-05 |
PS
Planned sale
|
Metzger Michael A
Non-Executive Director
|
27,506
-54.0%
6.14
USD 168,895
|
27,506
-54.0%
|
6.14
|
USD 168,895
|
|
|
2022-07-07 |
2022-07-05 |
PS
Planned sale
|
Metzger Michael A
Non-Executive Director
|
51,963
-50.5%
6.05
USD 314,439
|
51,963
-50.5%
|
6.05
|
USD 314,439
|
|
|
2022-07-07 |
2022-07-05 |
PS
Planned sale
|
Metzger Michael A
Non-Executive Director
|
8,700
-7.8%
5.98
USD 51,996
|
8,700
-7.8%
|
5.98
|
USD 51,996
|
|
|
2022-07-06 |
2022-07-05 |
PS
Planned sale
|
Craig Adam R
President and CEO
Executive Director
|
27,000
-54.2%
6.00
USD 162,000
|
27,000
-54.2%
|
6.00
|
USD 162,000
|
|
|
2022-07-06 |
2022-07-01 |
PS
Planned sale
|
Craig Adam R
President and CEO
Executive Director
|
27,000
-54.2%
6.00
USD 162,000
|
27,000
-54.2%
|
6.00
|
USD 162,000
|
|
|
2022-06-17 |
2022-06-17 |
PS
Planned sale
|
KIRSKE DAVID
EVP, Chief Financial Officer
Officer
|
50,000
-87.1%
6.25
USD 312,505
|
50,000
-87.1%
|
6.25
|
USD 312,505
|
|
|
2022-06-17 |
2022-06-17 |
PS
Planned sale
|
KIRSKE DAVID
EVP, Chief Financial Officer
Officer
|
10,000
-57.5%
6.00
USD 60,000
|
10,000
-57.5%
|
6.00
|
USD 60,000
|
|
|
2022-06-16 |
2022-06-14 |
PS
Planned sale
|
KIRSKE DAVID
EVP, Chief Financial Officer
Officer
|
10,000
-57.5%
5.50
USD 55,000
|
10,000
-57.5%
|
5.50
|
USD 55,000
|
|
|
2022-06-03 |
2022-06-03 |
PS
Planned sale
|
Craig Adam R
President and CEO
Executive Director
|
18,223
-52.2%
6.01
USD 109,520
|
18,223
-52.2%
|
6.01
|
USD 109,520
|
|
|
2022-06-03 |
2022-06-02 |
PS
Planned sale
|
Craig Adam R
President and CEO
Executive Director
|
27,000
-61.8%
6.00
USD 162,000
|
27,000
-61.8%
|
6.00
|
USD 162,000
|
|
|
2022-06-03 |
2022-06-01 |
PS
Planned sale
|
Craig Adam R
President and CEO
Executive Director
|
27,000
-61.8%
6.00
USD 162,000
|
27,000
-61.8%
|
6.00
|
USD 162,000
|
|
|
2021-12-02 |
2021-12-02 |
B
Purchase
|
Craig Adam R
President and CEO
Executive Director
|
2,178
+19.2%
1.53
USD 3,321
|
2,178
+19.2%
|
1.53
|
USD 3,321
|
|
|
2021-12-02 |
2021-12-02 |
B
Purchase
|
Craig Adam R
President and CEO
Executive Director
|
1,322
+13.2%
1.52
USD 2,016
|
1,322
+13.2%
|
1.52
|
USD 2,016
|
|
|
2021-04-05 |
2021-04-01 |
B
Purchase
|
BVF PARTNERS L P/IL
Non-Executive Director
Large shareholder
|
5,171
+1.1%
2.50
USD 12,928
|
5,171
+1.1%
|
2.50
|
USD 12,928
|
|
|
2021-04-05 |
2021-04-01 |
B
Purchase
|
BVF PARTNERS L P/IL
Non-Executive Director
Large shareholder
|
950,016
+45.0%
2.50
USD 2,375,040
|
950,016
+45.0%
|
2.50
|
USD 2,375,040
|
|
|
2021-04-05 |
2021-04-01 |
B
Purchase
|
BVF PARTNERS L P/IL
Non-Executive Director
Large shareholder
|
1,044,813
+34.4%
2.50
USD 2,612,033
|
1,044,813
+34.4%
|
2.50
|
USD 2,612,033
|
|
|
2021-01-11 |
2021-01-07 |
S
Sale
|
ORBIMED ADVISORS LLC
Large shareholder
|
2,000,000
-21.0%
3.50
USD 7,000,000
|
2,000,000
-21.0%
|
3.50
|
USD 7,000,000
|
|
|
2018-02-12 |
2018-02-09 |
B
Purchase
|
BVF PARTNERS L P/IL
Large shareholder
|
699,225
+117.2%
3.00
USD 2,097,675
|
699,225
+117.2%
|
3.00
|
USD 2,097,675
|
|
|
2018-02-12 |
2018-02-09 |
B
Purchase
|
BVF PARTNERS L P/IL
Large shareholder
|
483,708
+inf%
3.00
USD 1,451,124
|
483,708
+inf%
|
3.00
|
USD 1,451,124
|
|
|
2018-02-12 |
2018-02-09 |
B
Purchase
|
BVF PARTNERS L P/IL
Large shareholder
|
2,109,280
+inf%
3.00
USD 6,327,840
|
2,109,280
+inf%
|
3.00
|
USD 6,327,840
|
|
|
2018-02-12 |
2018-02-09 |
B
Purchase
|
BVF PARTNERS L P/IL
Large shareholder
|
3,041,120
+inf%
3.00
USD 9,123,360
|
3,041,120
+inf%
|
3.00
|
USD 9,123,360
|
|
|
2017-10-02 |
2017-09-29 |
S
Sale
|
LOVE RICHARD L
Non-Executive Director
|
976
-1.3%
3.20
USD 3,123
|
976
-1.3%
|
3.20
|
USD 3,123
|
|
|
2017-10-02 |
2017-09-28 |
S
Sale
|
LOVE RICHARD L
Non-Executive Director
|
200
-0.3%
3.25
USD 650
|
200
-0.3%
|
3.25
|
USD 650
|
|
|
2017-10-02 |
2017-09-28 |
S
Sale
|
LOVE RICHARD L
Non-Executive Director
|
477
-0.6%
3.24
USD 1,545
|
477
-0.6%
|
3.24
|
USD 1,545
|
|
|
2017-10-02 |
2017-09-28 |
S
Sale
|
LOVE RICHARD L
Non-Executive Director
|
200
-0.3%
3.24
USD 647
|
200
-0.3%
|
3.24
|
USD 647
|
|
|
2017-10-02 |
2017-09-28 |
S
Sale
|
LOVE RICHARD L
Non-Executive Director
|
1,600
-2.1%
3.23
USD 5,168
|
1,600
-2.1%
|
3.23
|
USD 5,168
|
|
|
2017-10-02 |
2017-09-28 |
S
Sale
|
LOVE RICHARD L
Non-Executive Director
|
1,675
-2.1%
3.23
USD 5,410
|
1,675
-2.1%
|
3.23
|
USD 5,410
|
|
