|
2006-02-24 |
2006-02-22 |
PS
Planned sale
|
Feldman Thomas
Chief Business Officer
Officer
|
12,500
-9.8%
11.12
USD 139,000
|
12,500
-9.8%
|
11.12
|
USD 139,000
|
|
|
2006-02-24 |
2006-02-22 |
PS
Planned sale
|
Feldman Thomas
Chief Business Officer
Officer
|
7,500
-5.6%
11.00
USD 82,500
|
7,500
-5.6%
|
11.00
|
USD 82,500
|
|
|
2006-02-24 |
2006-02-22 |
PS
Planned sale
|
Feldman Thomas
Chief Business Officer
Officer
|
15,000
-12.0%
11.00
USD 165,000
|
15,000
-12.0%
|
11.00
|
USD 165,000
|
|
|
2005-10-19 |
2005-10-19 |
S
Sale
|
MPM BIOVENTURES III QP LP
Large shareholder
|
170,563
-4.6%
13.00
USD 2,217,319
|
170,563
-4.6%
|
13.00
|
USD 2,217,319
|
|
|
2005-10-19 |
2005-10-19 |
S
Sale
|
EVNIN LUKE
Large shareholder
|
170,563
-4.6%
13.00
USD 2,217,319
|
170,563
-4.6%
|
13.00
|
USD 2,217,319
|
|
|
2005-10-19 |
2005-10-19 |
S
Sale
|
SIMON NICHOLAS J III
Non-Executive Director
Large shareholder
|
170,563
-4.6%
13.00
USD 2,217,319
|
170,563
-4.6%
|
13.00
|
USD 2,217,319
|
|
|
2005-10-18 |
2005-10-14 |
S
Sale
|
ALTA BIOPHARMA PARTNERS III LP
Large shareholder
|
3,769
-15.0%
13.00
USD 48,997
|
3,769
-15.0%
|
13.00
|
USD 48,997
|
|
|
2005-10-18 |
2005-10-14 |
S
Sale
|
ALTA BIOPHARMA PARTNERS III LP
Large shareholder
|
10,268
-15.0%
13.00
USD 133,484
|
10,268
-15.0%
|
13.00
|
USD 133,484
|
|
|
2005-10-18 |
2005-10-14 |
S
Sale
|
ALTA BIOPHARMA PARTNERS III LP
Large shareholder
|
152,900
-15.0%
13.00
USD 1,987,700
|
152,900
-15.0%
|
13.00
|
USD 1,987,700
|
|
|
2005-10-18 |
2005-10-14 |
S
Sale
|
JANNEY DANIEL
Non-Executive Director
Large shareholder
|
3,769
-15.0%
13.00
USD 48,997
|
3,769
-15.0%
|
13.00
|
USD 48,997
|
|
|
2005-10-18 |
2005-10-14 |
S
Sale
|
JANNEY DANIEL
Non-Executive Director
Large shareholder
|
10,268
-15.0%
13.00
USD 133,484
|
10,268
-15.0%
|
13.00
|
USD 133,484
|
|
|
2005-10-18 |
2005-10-14 |
S
Sale
|
JANNEY DANIEL
Non-Executive Director
Large shareholder
|
152,900
-15.0%
13.00
USD 1,987,700
|
152,900
-15.0%
|
13.00
|
USD 1,987,700
|
|
|
2005-10-14 |
2005-10-12 |
S
Sale
|
JANNEY DANIEL
Non-Executive Director
Large shareholder
|
5,582
-18.1%
13.00
USD 72,566
|
5,582
-18.1%
|
13.00
|
USD 72,566
|
|
|
2005-10-14 |
2005-10-12 |
S
Sale
|
JANNEY DANIEL
Non-Executive Director
Large shareholder
|
15,213
-18.1%
13.00
USD 197,769
|
15,213
-18.1%
|
13.00
|
USD 197,769
|
|
|
2005-10-14 |
2005-10-12 |
S
Sale
|
JANNEY DANIEL
Non-Executive Director
Large shareholder
|
226,519
-18.1%
13.00
USD 2,944,747
|
226,519
-18.1%
|
13.00
|
USD 2,944,747
|
|
|
2005-10-14 |
2005-10-12 |
S
Sale
|
ALTA BIOPHARMA PARTNERS III LP
Large shareholder
|
5,582
-18.1%
13.00
USD 72,566
|
5,582
-18.1%
|
13.00
|
USD 72,566
|
|
|
2005-10-14 |
2005-10-12 |
S
Sale
|
ALTA BIOPHARMA PARTNERS III LP
Large shareholder
|
15,213
-18.1%
13.00
USD 197,769
|
15,213
-18.1%
|
13.00
|
USD 197,769
|
|
|
2005-10-14 |
2005-10-12 |
S
Sale
|
ALTA BIOPHARMA PARTNERS III LP
Large shareholder
|
226,519
-18.1%
13.00
USD 2,944,747
|
226,519
-18.1%
|
13.00
|
USD 2,944,747
|
|
|
2005-10-13 |
2005-10-12 |
S
Sale
|
SIMON NICHOLAS J III
Non-Executive Director
Large shareholder
|
252,686
-6.3%
13.00
USD 3,284,918
|
252,686
-6.3%
|
13.00
|
USD 3,284,918
|
|
|
2005-10-13 |
2005-10-12 |
S
Sale
|
EVNIN LUKE
Large shareholder
|
252,686
-6.3%
13.00
USD 3,284,918
|
252,686
-6.3%
|
13.00
|
USD 3,284,918
|
|
|
2005-10-13 |
2005-10-12 |
S
Sale
|
MPM BIOVENTURES III QP LP
Large shareholder
|
252,686
-6.3%
13.00
USD 3,284,918
|
252,686
-6.3%
|
13.00
|
USD 3,284,918
|
|
|
2004-10-21 |
2004-10-20 |
B
Purchase
|
SIMON NICHOLAS J III
Large shareholder
|
554,617
+16.1%
6.00
USD 3,327,702
|
554,617
+16.1%
|
6.00
|
USD 3,327,702
|
|
|
2004-10-21 |
2004-10-20 |
B
Purchase
|
EVNIN LUKE
Large shareholder
|
554,617
+16.1%
6.00
USD 3,327,702
|
554,617
+16.1%
|
6.00
|
USD 3,327,702
|
|
|
2004-10-21 |
2004-10-20 |
B
Purchase
|
MPM BIOVENTURES III QP LP
Large shareholder
|
554,617
+16.1%
6.00
USD 3,327,702
|
554,617
+16.1%
|
6.00
|
USD 3,327,702
|
|
|
2004-10-19 |
2004-10-15 |
B
Purchase
|
HEALY JAMES
Large shareholder
|
5,243
+252.2%
6.00
USD 31,458
|
5,243
+252.2%
|
6.00
|
USD 31,458
|
|
|
2004-10-19 |
2004-10-15 |
B
Purchase
|
HEALY JAMES
Large shareholder
|
341,933
+252.1%
6.00
USD 2,051,598
|
341,933
+252.1%
|
6.00
|
USD 2,051,598
|
|
|
2004-10-19 |
2004-10-15 |
B
Purchase
|
HEALY JAMES
Large shareholder
|
11,250
+252.1%
6.00
USD 67,500
|
11,250
+252.1%
|
6.00
|
USD 67,500
|
|
|
2004-10-19 |
2004-10-15 |
B
Purchase
|
ALTA PARTNERS II INC
Large shareholder
|
416,666
+20.8%
6.00
USD 2,499,996
|
416,666
+20.8%
|
6.00
|
USD 2,499,996
|
|
|
2004-10-19 |
2004-10-15 |
B
Purchase
|
JANNEY DANIEL
Large shareholder
|
416,666
+20.8%
6.00
USD 2,499,996
|
416,666
+20.8%
|
6.00
|
USD 2,499,996
|
|
