2024-05-07 |
2024-05-06 |
B
Purchase
|
MILLER RICHARD A MD
President and CEO
Executive Director
|
577,634
+inf%
1.73
USD 1,000,000
|
577,634
+inf%
|
1.73
|
USD 1,000,000
|
|
2024-05-07 |
2024-05-06 |
B
Purchase
|
MILLER RICHARD A MD
President and CEO
Executive Director
|
577,634
+inf%
1.73
USD 1,000,000
|
577,634
+inf%
|
1.73
|
USD 1,000,000
|
|
2024-05-07 |
2024-05-06 |
B
Purchase
|
Jones William Benton
See Remarks
Officer
|
20,000
+15.0%
1.73
USD 34,624
|
20,000
+15.0%
|
1.73
|
USD 34,624
|
|
2023-05-16 |
2023-05-15 |
B
Purchase
|
Grais Linda
Non-Executive Director
|
10,000
+inf%
2.45
USD 24,500
|
10,000
+inf%
|
2.45
|
USD 24,500
|
|
2022-12-20 |
2022-12-20 |
B
Purchase
|
Jones William Benton
See Remarks
Officer
|
20,000
+17.6%
0.79
USD 15,800
|
20,000
+17.6%
|
0.79
|
USD 15,800
|
|
2022-12-15 |
2022-12-14 |
B
Purchase
|
MILLER RICHARD A MD
President and CEO
Executive Director
|
10,000
+0.7%
0.78
USD 7,812
|
10,000
+0.7%
|
0.78
|
USD 7,812
|
|
2022-12-15 |
2022-12-14 |
B
Purchase
|
LEA LEIV
Chief Financial Officer
Officer
|
4,000
+3.1%
0.84
USD 3,364
|
4,000
+3.1%
|
0.84
|
USD 3,364
|
|
2022-12-15 |
2022-12-13 |
B
Purchase
|
MILLER RICHARD A MD
President and CEO
Executive Director
|
50,000
+3.5%
0.74
USD 37,015
|
50,000
+3.5%
|
0.74
|
USD 37,015
|
|
2022-12-15 |
2022-12-13 |
B
Purchase
|
LEA LEIV
Chief Financial Officer
Officer
|
30,000
+30.2%
0.74
USD 22,275
|
30,000
+30.2%
|
0.74
|
USD 22,275
|
|
2022-09-28 |
2022-09-28 |
B
Purchase
|
MILLER RICHARD A MD
President and CEO
Executive Director
|
25,000
+1.8%
0.76
USD 19,070
|
25,000
+1.8%
|
0.76
|
USD 19,070
|
|
2022-09-20 |
2022-09-20 |
B
Purchase
|
MILLER RICHARD A MD
President and CEO
Executive Director
|
5,000
+0.4%
0.82
USD 4,075
|
5,000
+0.4%
|
0.82
|
USD 4,075
|
|
2022-09-20 |
2022-09-20 |
B
Purchase
|
MILLER RICHARD A MD
President and CEO
Executive Director
|
2,700
+0.2%
0.82
USD 2,214
|
2,700
+0.2%
|
0.82
|
USD 2,214
|
|
2022-09-20 |
2022-09-20 |
B
Purchase
|
MILLER RICHARD A MD
President and CEO
Executive Director
|
12,300
+0.9%
0.81
USD 9,964
|
12,300
+0.9%
|
0.81
|
USD 9,964
|
|
2022-06-28 |
2022-06-27 |
B
Purchase
|
MILLER RICHARD A MD
President and CEO
Executive Director
|
5,000
+0.4%
1.00
USD 4,985
|
5,000
+0.4%
|
1.00
|
USD 4,985
|
|
2022-06-28 |
2022-06-24 |
B
Purchase
|
MILLER RICHARD A MD
President and CEO
Executive Director
|
5,000
+0.4%
1.03
USD 5,150
|
5,000
+0.4%
|
1.03
|
USD 5,150
|
|
2022-06-06 |
2022-06-06 |
B
Purchase
|
MILLER RICHARD A MD
President and CEO
Executive Director
|
890
+0.1%
1.01
USD 899
|
890
+0.1%
|
1.01
|
USD 899
|
|
2022-06-06 |
2022-06-02 |
B
Purchase
|
MILLER RICHARD A MD
President and CEO
Executive Director
|
170
+0.0%
0.97
USD 165
|
170
+0.0%
|
0.97
|
USD 165
|
|
2022-06-06 |
2022-06-02 |
B
Purchase
|
MILLER RICHARD A MD
President and CEO
Executive Director
|
4,830
+0.4%
0.98
USD 4,733
|
4,830
+0.4%
|
0.98
|
USD 4,733
|
|
2022-04-01 |
2022-03-31 |
B
Purchase
|
MILLER RICHARD A MD
President and CEO
Executive Director
|
15,000
+1.1%
1.64
USD 24,534
|
15,000
+1.1%
|
1.64
|
USD 24,534
|
|
2022-03-17 |
2022-03-17 |
B
Purchase
|
LEA LEIV
Chief Financial Officer
Officer
|
13,878
+16.3%
1.65
USD 22,899
|
13,878
+16.3%
|
1.65
|
USD 22,899
|
|
2022-03-17 |
2022-03-17 |
B
Purchase
|
MILLER RICHARD A MD
President and CEO
Executive Director
|
5,000
+0.4%
1.59
USD 7,950
|
5,000
+0.4%
|
1.59
|
USD 7,950
|
|
2022-03-17 |
2022-03-16 |
B
Purchase
|
LEA LEIV
Chief Financial Officer
Officer
|
35,160
+70.0%
1.54
USD 54,146
|
35,160
+70.0%
|
1.54
|
USD 54,146
|
|
2022-03-17 |
2022-03-15 |
B
Purchase
|
MILLER RICHARD A MD
President and CEO
Executive Director
|
25,000
+1.9%
1.47
USD 36,650
|
25,000
+1.9%
|
1.47
|
USD 36,650
|
|
2021-10-01 |
2021-10-01 |
S
Sale
|
EcoR1 Capital, LLC
Large shareholder
|
2,000,000
-96.1%
4.96
USD 9,928,800
|
2,000,000
-96.1%
|
4.96
|
USD 9,928,800
|
|
2021-10-01 |
2021-09-30 |
S
Sale
|
EcoR1 Capital, LLC
Large shareholder
|
3,000,000
-59.0%
5.04
USD 15,131,100
|
3,000,000
-59.0%
|
5.04
|
USD 15,131,100
|
|
2021-02-19 |
2021-02-17 |
B
Purchase
|
ORBIMED ADVISORS LLC
Non-Executive Director
Large shareholder
|
1,285,714
+19.0%
3.50
USD 4,499,999
|
1,285,714
+19.0%
|
3.50
|
USD 4,499,999
|
|
2021-02-19 |
2021-02-17 |
B
Purchase
|
Thompson Peter A.
Non-Executive Director
Large shareholder
|
1,285,714
+19.0%
3.50
USD 4,499,999
|
1,285,714
+19.0%
|
3.50
|
USD 4,499,999
|
|
2021-02-17 |
2021-02-17 |
B
Purchase
|
MILLER RICHARD A MD
President and CEO
Executive Director
|
100,000
+8.5%
3.50
USD 350,000
|
100,000
+8.5%
|
3.50
|
USD 350,000
|
|
2020-07-09 |
2020-07-08 |
S
Sale
|
Novo Holdings A/S
Large shareholder
|
741,440
-34.8%
5.37
USD 3,985,166
|
741,440
-34.8%
|
5.37
|
USD 3,985,166
|
|
2020-07-09 |
2020-07-07 |
S
Sale
|
Novo Holdings A/S
Large shareholder
|
796,622
-27.2%
5.25
USD 4,183,381
|
796,622
-27.2%
|
5.25
|
USD 4,183,381
|
|
2019-11-14 |
2019-11-13 |
B
Purchase
|
MILLER RICHARD A MD
President and CEO
Executive Director
|
14,736
+1.3%
3.00
USD 44,240
|
14,736
+1.3%
|
3.00
|
USD 44,240
|
|
2019-11-14 |
2019-11-12 |
B
Purchase
|
MILLER RICHARD A MD
President and CEO
Executive Director
|
272
+0.0%
2.90
USD 789
|
272
+0.0%
|
2.90
|
USD 789
|
|
2019-08-08 |
2019-08-07 |
B
Purchase
|
MILLER RICHARD A MD
President and CEO
Executive Director
|
2,500
+0.2%
3.54
USD 8,850
|
2,500
+0.2%
|
3.54
|
USD 8,850
|
|
2019-08-08 |
2019-08-06 |
B
Purchase
|
MILLER RICHARD A MD
President and CEO
Executive Director
|
5,000
+0.4%
3.58
USD 17,875
|
5,000
+0.4%
|
3.58
|
USD 17,875
|
|
2019-08-08 |
2019-08-06 |
B
Purchase
|
ORBIMED ADVISORS LLC
Non-Executive Director
Large shareholder
|
142,656
+2.2%
3.51
USD 500,723
|
142,656
+2.2%
|
3.51
|
USD 500,723
|
|
2019-08-08 |
2019-08-06 |
B
Purchase
|
Thompson Peter A.
Non-Executive Director
Large shareholder
|
142,656
+2.2%
3.51
USD 500,723
|
142,656
+2.2%
|
3.51
|
USD 500,723
|
|
2019-07-25 |
2019-07-25 |
S
Sale
|
Novo Holdings A/S
Large shareholder
|
1,400,000
-32.4%
4.00
USD 5,600,000
|
1,400,000
-32.4%
|
4.00
|
USD 5,600,000
|
|
2019-07-25 |
2019-07-24 |
S
Sale
|
Novo Holdings A/S
Large shareholder
|
53,240
-1.2%
5.01
USD 266,711
|
53,240
-1.2%
|
5.01
|
USD 266,711
|
|
2019-07-25 |
2019-07-23 |
S
Sale
|
Novo Holdings A/S
Large shareholder
|
39,716
-0.9%
5.32
USD 211,134
|
39,716
-0.9%
|
5.32
|
USD 211,134
|
|
2019-07-01 |
2019-07-01 |
B
Purchase
|
Thompson Peter A.
Large shareholder
|
59,243
+0.9%
3.91
USD 231,640
|
59,243
+0.9%
|
3.91
|
USD 231,640
|
|
2019-07-01 |
2019-07-01 |
B
Purchase
|
ORBIMED ADVISORS LLC
Large shareholder
|
59,243
+0.9%
3.91
USD 231,640
|
59,243
+0.9%
|
3.91
|
USD 231,640
|
|
2019-07-01 |
2019-06-28 |
B
Purchase
|
Thompson Peter A.
Large shareholder
|
565,178
+9.4%
3.72
USD 2,102,462
|
565,178
+9.4%
|
3.72
|
USD 2,102,462
|
|
2019-07-01 |
2019-06-28 |
B
Purchase
|
ORBIMED ADVISORS LLC
Large shareholder
|
565,178
+9.4%
3.72
USD 2,102,462
|
565,178
+9.4%
|
3.72
|
USD 2,102,462
|
|
2019-07-01 |
2019-06-27 |
B
Purchase
|
Thompson Peter A.
Large shareholder
|
32,923
+0.6%
3.34
USD 109,963
|
32,923
+0.6%
|
3.34
|
USD 109,963
|
|
2019-07-01 |
2019-06-27 |
B
Purchase
|
ORBIMED ADVISORS LLC
Large shareholder
|
32,923
+0.6%
3.34
USD 109,963
|
32,923
+0.6%
|
3.34
|
USD 109,963
|
|
2019-06-17 |
2019-06-14 |
B
Purchase
|
MILLER RICHARD A MD
President and CEO
Executive Director
|
11,657
+1.0%
3.40
USD 39,666
|
11,657
+1.0%
|
3.40
|
USD 39,666
|
|
2019-06-17 |
2019-06-13 |
B
Purchase
|
MILLER RICHARD A MD
President and CEO
Executive Director
|
343
+0.0%
3.52
USD 1,207
|
343
+0.0%
|
3.52
|
USD 1,207
|
|
2019-06-11 |
2019-06-11 |
B
Purchase
|
MILLER RICHARD A MD
President and CEO
Executive Director
|
6,000
+0.5%
3.67
USD 22,020
|
6,000
+0.5%
|
3.67
|
USD 22,020
|
|
2019-06-11 |
2019-06-07 |
B
Purchase
|
MILLER RICHARD A MD
President and CEO
Executive Director
|
9,212
+0.8%
3.37
USD 31,019
|
9,212
+0.8%
|
3.37
|
USD 31,019
|
|
2019-06-10 |
2019-06-07 |
B
Purchase
|
LEA LEIV
Chief Financial Officer
|
10,000
+24.9%
3.38
USD 33,800
|
10,000
+24.9%
|
3.38
|
USD 33,800
|
|
2019-06-10 |
2019-06-06 |
B
Purchase
|
LEA LEIV
Chief Financial Officer
|
15,500
+62.8%
3.56
USD 55,180
|
15,500
+62.8%
|
3.56
|
USD 55,180
|
|
2018-12-31 |
2018-12-27 |
B
Purchase
|
MILLER RICHARD A MD
President and CEO
Executive Director
|
20,000
+1.8%
3.29
USD 65,884
|
20,000
+1.8%
|
3.29
|
USD 65,884
|
|
2018-12-27 |
2018-12-21 |
B
Purchase
|
LEA LEIV
Chief Financial Officer
Officer
|
24,700
+inf%
4.15
USD 102,409
|
24,700
+inf%
|
4.15
|
USD 102,409
|
|
2018-12-26 |
2018-12-20 |
B
Purchase
|
MILLER RICHARD A MD
President and CEO
Executive Director
|
5,000
+0.5%
4.39
USD 21,950
|
5,000
+0.5%
|
4.39
|
USD 21,950
|
|
2018-12-26 |
2018-12-20 |
B
Purchase
|
MILLER RICHARD A MD
President and CEO
Executive Director
|
5,000
+0.5%
4.40
USD 22,000
|
5,000
+0.5%
|
4.40
|
USD 22,000
|
|
2018-12-10 |
2018-12-06 |
B
Purchase
|
MILLER RICHARD A MD
President and CEO
Executive Director
|
5,000
+0.4%
5.99
USD 29,934
|
5,000
+0.4%
|
5.99
|
USD 29,934
|
|
2018-12-06 |
2018-12-04 |
B
Purchase
|
MILLER RICHARD A MD
President and CEO
Executive Director
|
1,502
+0.1%
5.95
USD 8,937
|
1,502
+0.1%
|
5.95
|
USD 8,937
|
|
2018-03-14 |
2018-03-12 |
B
Purchase
|
Thompson Peter A.
Large shareholder
|
588,235
+10.9%
8.50
USD 4,999,998
|
588,235
+10.9%
|
8.50
|
USD 4,999,998
|
|
2018-03-14 |
2018-03-12 |
B
Purchase
|
ORBIMED ADVISORS LLC
Large shareholder
|
588,235
+10.9%
8.50
USD 4,999,998
|
588,235
+10.9%
|
8.50
|
USD 4,999,998
|
|
2018-03-13 |
2018-03-12 |
B
Purchase
|
Novo Holdings A/S
Large shareholder
|
1,176,470
+36.3%
8.50
USD 9,999,995
|
1,176,470
+36.3%
|
8.50
|
USD 9,999,995
|
|
2018-03-13 |
2018-03-12 |
B
Purchase
|
ADAMS STREET PARTNERS LLC
Large shareholder
|
126,806
+inf%
8.50
USD 1,077,851
|
126,806
+inf%
|
8.50
|
USD 1,077,851
|
|
2018-03-13 |
2018-03-12 |
B
Purchase
|
ADAMS STREET PARTNERS LLC
Large shareholder
|
87,668
+inf%
8.50
USD 745,178
|
87,668
+inf%
|
8.50
|
USD 745,178
|
|
2018-03-13 |
2018-03-12 |
B
Purchase
|
ADAMS STREET PARTNERS LLC
Large shareholder
|
67,769
+inf%
8.50
USD 576,037
|
67,769
+inf%
|
8.50
|
USD 576,037
|
|
2018-03-13 |
2018-03-12 |
B
Purchase
|
ADAMS STREET PARTNERS LLC
Large shareholder
|
236,128
+inf%
8.50
USD 2,007,088
|
236,128
+inf%
|
8.50
|
USD 2,007,088
|
|
2018-03-13 |
2018-03-12 |
B
Purchase
|
ADAMS STREET PARTNERS LLC
Large shareholder
|
69,864
+inf%
8.50
USD 593,844
|
69,864
+inf%
|
8.50
|
USD 593,844
|
|
2018-03-13 |
2018-03-12 |
B
Purchase
|
Gould Terry P
Large shareholder
|
126,806
+inf%
8.50
USD 1,077,851
|
126,806
+inf%
|
8.50
|
USD 1,077,851
|
|
2018-03-13 |
2018-03-12 |
B
Purchase
|
Gould Terry P
Large shareholder
|
87,668
+inf%
8.50
USD 745,178
|
87,668
+inf%
|
8.50
|
USD 745,178
|
|
2018-03-13 |
2018-03-12 |
B
Purchase
|
Gould Terry P
Large shareholder
|
67,769
+inf%
8.50
USD 576,037
|
67,769
+inf%
|
8.50
|
USD 576,037
|
|
2018-03-13 |
2018-03-12 |
B
Purchase
|
Gould Terry P
Large shareholder
|
236,128
+inf%
8.50
USD 2,007,088
|
236,128
+inf%
|
8.50
|
USD 2,007,088
|
|
2018-03-13 |
2018-03-12 |
B
Purchase
|
Gould Terry P
Large shareholder
|
69,864
+inf%
8.50
USD 593,844
|
69,864
+inf%
|
8.50
|
USD 593,844
|
|
2018-03-12 |
2018-03-12 |
B
Purchase
|
MILLER RICHARD A MD
President and CEO
Executive Director
|
100,000
+9.9%
8.50
USD 850,000
|
100,000
+9.9%
|
8.50
|
USD 850,000
|
|
2017-11-22 |
2017-11-20 |
B
Purchase
|
MILLER RICHARD A MD
President and CEO
Executive Director
|
10,000
+1.0%
10.79
USD 107,850
|
10,000
+1.0%
|
10.79
|
USD 107,850
|
|
2017-06-27 |
2017-06-23 |
B
Purchase
|
Novo Holdings A/S
Large shareholder
|
20,000
+0.6%
10.95
USD 219,000
|
20,000
+0.6%
|
10.95
|
USD 219,000
|
|
2017-06-13 |
2017-06-13 |
B
Purchase
|
MILLER RICHARD A MD
President and CEO
Executive Director
|
2,500
+0.3%
10.14
USD 25,350
|
2,500
+0.3%
|
10.14
|
USD 25,350
|
|
2017-06-13 |
2017-06-13 |
B
Purchase
|
MILLER RICHARD A MD
President and CEO
Executive Director
|
2,500
+0.3%
9.75
USD 24,375
|
2,500
+0.3%
|
9.75
|
USD 24,375
|
|