|
2021-02-23 |
2021-02-22 |
PS
Planned sale
|
Reeve Emma
Chief Financial Officer
Officer
|
6,260
-100.0%
37.60
USD 235,373
|
6,260
-100.0%
|
37.60
|
USD 235,373
|
|
|
2021-02-23 |
2021-02-19 |
PS
Planned sale
|
Reeve Emma
Chief Financial Officer
Officer
|
4,010
-100.0%
37.71
USD 151,218
|
4,010
-100.0%
|
37.71
|
USD 151,218
|
|
|
2021-02-19 |
2021-02-18 |
PS
Planned sale
|
Reeve Emma
Chief Financial Officer
Officer
|
1,100
-100.0%
37.58
USD 41,343
|
1,100
-100.0%
|
37.58
|
USD 41,343
|
|
|
2021-02-19 |
2021-02-17 |
PS
Planned sale
|
Reeve Emma
Chief Financial Officer
Officer
|
410
-100.0%
37.56
USD 15,398
|
410
-100.0%
|
37.56
|
USD 15,398
|
|
|
2021-02-19 |
2021-02-17 |
S
Sale
|
COLUMN GROUP L P
Large shareholder
|
10,000
-9.2%
36.95
USD 369,503
|
10,000
-9.2%
|
36.95
|
USD 369,503
|
|
|
2021-02-19 |
2021-02-17 |
S
Sale
|
COLUMN GROUP L P
Large shareholder
|
10,000
-9.2%
36.95
USD 369,503
|
10,000
-9.2%
|
36.95
|
USD 369,503
|
|
|
2021-01-20 |
2021-01-19 |
PS
Planned sale
|
Valentine Karen
See Remarks
Officer
|
7,203
-100.0%
35.11
USD 252,889
|
7,203
-100.0%
|
35.11
|
USD 252,889
|
|
|
2021-01-20 |
2021-01-19 |
PS
Planned sale
|
Valentine Karen
See Remarks
Officer
|
1,227
-14.6%
33.69
USD 41,342
|
1,227
-14.6%
|
33.69
|
USD 41,342
|
|
|
2021-01-20 |
2021-01-19 |
PS
Planned sale
|
Valentine Karen
See Remarks
Officer
|
8,773
-51.0%
33.08
USD 290,232
|
8,773
-51.0%
|
33.08
|
USD 290,232
|
|
|
2020-12-28 |
2020-12-21 |
PS
Planned sale
|
GOLDSMITH MARK A
Non-Executive Director
Large shareholder
|
4,020
-2.8%
35.02
USD 140,769
|
4,020
-2.8%
|
35.02
|
USD 140,769
|
|
|
2020-12-22 |
2020-12-21 |
PS
Planned sale
|
Reeve Emma
Chief Financial Officer
Officer
|
5,720
-100.0%
35.11
USD 200,805
|
5,720
-100.0%
|
35.11
|
USD 200,805
|
|
|
2020-06-10 |
2020-06-08 |
PS
Planned sale
|
Reeve Emma
Chief Financial Officer
Officer
|
233
-100.0%
38.35
USD 8,936
|
233
-100.0%
|
38.35
|
USD 8,936
|
|
|
2020-06-10 |
2020-06-08 |
PS
Planned sale
|
Reeve Emma
Chief Financial Officer
Officer
|
144
-38.2%
37.67
USD 5,424
|
144
-38.2%
|
37.67
|
USD 5,424
|
|
|
2020-06-10 |
2020-06-08 |
PS
Planned sale
|
Reeve Emma
Chief Financial Officer
Officer
|
212
-36.0%
36.59
USD 7,757
|
212
-36.0%
|
36.59
|
USD 7,757
|
|
|
2020-05-13 |
2020-05-12 |
PS
Planned sale
|
Raythatha Jigar
See Remarks
Executive Director
|
9,209
-38.1%
50.17
USD 461,981
|
9,209
-38.1%
|
50.17
|
USD 461,981
|
|
|
2020-05-13 |
2020-05-12 |
PS
Planned sale
|
Senderowicz Adrian
Chief Medical Officer
Officer
|
9,357
-37.1%
50.18
USD 469,488
|
9,357
-37.1%
|
50.18
|
USD 469,488
|
|
|
2020-05-13 |
2020-05-12 |
PS
Planned sale
|
GOLDSMITH MARK A
Non-Executive Director
Large shareholder
|
4,225
-2.9%
50.05
USD 211,474
|
4,225
-2.9%
|
50.05
|
USD 211,474
|
|
|
2020-05-13 |
2020-05-12 |
PS
Planned sale
|
Audia James E
Non-Executive Director
|
6,100
-19.3%
50.10
USD 305,622
|
6,100
-19.3%
|
50.10
|
USD 305,622
|
|
|
2020-05-13 |
2020-05-11 |
PS
Planned sale
|
Raythatha Jigar
See Remarks
Executive Director
|
26
-0.2%
50.00
USD 1,300
|
26
-0.2%
|
50.00
|
USD 1,300
|
|
|
2020-05-13 |
2020-05-11 |
PS
Planned sale
|
GOLDSMITH MARK A
Non-Executive Director
Large shareholder
|
100
-0.1%
50.00
USD 5,000
|
100
-0.1%
|
50.00
|
USD 5,000
|
|
|
2020-05-12 |
2020-05-11 |
PS
Planned sale
|
Reeve Emma
Chief Financial Officer
Officer
|
16,062
-100.0%
49.53
USD 795,623
|
16,062
-100.0%
|
49.53
|
USD 795,623
|
|
|
2020-05-12 |
2020-05-08 |
PS
Planned sale
|
Reeve Emma
Chief Financial Officer
Officer
|
12,741
-100.0%
49.53
USD 631,055
|
12,741
-100.0%
|
49.53
|
USD 631,055
|
|
|
2020-05-07 |
2020-05-06 |
PS
Planned sale
|
Valentine Karen
See Remarks
|
12,566
-100.0%
40.10
USD 503,897
|
12,566
-100.0%
|
40.10
|
USD 503,897
|
|
|
2020-05-07 |
2020-05-06 |
PS
Planned sale
|
Audia James E
|
7,500
-19.2%
45.15
USD 338,600
|
7,500
-19.2%
|
45.15
|
USD 338,600
|
|
|
2020-05-07 |
2020-05-06 |
PS
Planned sale
|
GOLDSMITH MARK A
|
11,463
-7.4%
45.06
USD 516,545
|
11,463
-7.4%
|
45.06
|
USD 516,545
|
|
|
2020-05-07 |
2020-05-06 |
PS
Planned sale
|
Trojer Patrick
Chief Scientific Officer
|
10,000
-100.0%
45.16
USD 451,553
|
10,000
-100.0%
|
45.16
|
USD 451,553
|
|
|
2020-05-07 |
2020-05-05 |
PS
Planned sale
|
Valentine Karen
See Remarks
|
4,744
-100.0%
40.01
USD 189,817
|
4,744
-100.0%
|
40.01
|
USD 189,817
|
|
|
2020-05-07 |
2020-05-05 |
PS
Planned sale
|
GOLDSMITH MARK A
|
3,145
-2.2%
40.01
USD 125,824
|
3,145
-2.2%
|
40.01
|
USD 125,824
|
|
|
2020-04-29 |
2020-04-27 |
PS
Planned sale
|
Valentine Karen
See Remarks
|
400
-100.0%
40.13
USD 16,052
|
400
-100.0%
|
40.13
|
USD 16,052
|
|
|
2020-04-29 |
2020-04-27 |
PS
Planned sale
|
GOLDSMITH MARK A
|
400
-0.3%
40.12
USD 16,049
|
400
-0.3%
|
40.12
|
USD 16,049
|
|
|
2020-04-22 |
2020-04-20 |
PS
Planned sale
|
Valentine Karen
See Remarks
|
789
-100.0%
33.65
USD 26,550
|
789
-100.0%
|
33.65
|
USD 26,550
|
|
|
2020-04-20 |
2020-04-17 |
PS
Planned sale
|
Valentine Karen
See Remarks
|
2,300
-100.0%
35.19
USD 80,939
|
2,300
-100.0%
|
35.19
|
USD 80,939
|
|
|
2020-04-20 |
2020-04-17 |
PS
Planned sale
|
Reeve Emma
Chief Financial Officer
|
760
-100.0%
35.29
USD 26,820
|
760
-100.0%
|
35.29
|
USD 26,820
|
|
|
2020-04-20 |
2020-04-16 |
PS
Planned sale
|
Valentine Karen
See Remarks
|
1,043
-100.0%
34.09
USD 35,552
|
1,043
-100.0%
|
34.09
|
USD 35,552
|
|
|
2020-04-20 |
2020-04-16 |
PS
Planned sale
|
Valentine Karen
See Remarks
|
1,955
-65.2%
33.29
USD 65,085
|
1,955
-65.2%
|
33.29
|
USD 65,085
|
|
|
2020-04-16 |
2020-04-14 |
PS
Planned sale
|
Reeve Emma
Chief Financial Officer
|
1,225
-100.0%
35.20
USD 43,123
|
1,225
-100.0%
|
35.20
|
USD 43,123
|
|
|
2020-04-13 |
2020-04-09 |
PS
Planned sale
|
Reeve Emma
Chief Financial Officer
|
589
-100.0%
35.02
USD 20,626
|
589
-100.0%
|
35.02
|
USD 20,626
|
|
|
2020-04-13 |
2020-04-09 |
PS
Planned sale
|
Reeve Emma
Chief Financial Officer
|
111
-100.0%
35.02
USD 3,887
|
111
-100.0%
|
35.02
|
USD 3,887
|
|
|
2020-04-13 |
2020-04-09 |
PS
Planned sale
|
Valentine Karen
See Remarks
|
635
-100.0%
35.02
USD 22,236
|
635
-100.0%
|
35.02
|
USD 22,236
|
|
|
2020-03-23 |
2020-03-20 |
B
Purchase
|
COLUMN GROUP L P
General Partner
Large shareholder
|
5,539
+0.1%
23.15
USD 128,228
|
5,539
+0.1%
|
23.15
|
USD 128,228
|
|
|
2020-03-23 |
2020-03-20 |
B
Purchase
|
COLUMN GROUP L P
General Partner
Large shareholder
|
5,539
+0.1%
23.15
USD 128,228
|
5,539
+0.1%
|
23.15
|
USD 128,228
|
|
|
2020-03-23 |
2020-03-19 |
B
Purchase
|
COLUMN GROUP L P
General Partner
Large shareholder
|
36,135
+0.6%
22.38
USD 808,701
|
36,135
+0.6%
|
22.38
|
USD 808,701
|
|
|
2020-03-23 |
2020-03-19 |
B
Purchase
|
COLUMN GROUP L P
General Partner
Large shareholder
|
36,135
+0.6%
22.38
USD 808,701
|
36,135
+0.6%
|
22.38
|
USD 808,701
|
|
|
2020-03-11 |
2020-03-09 |
PS
Planned sale
|
Valentine Karen
See Remarks
|
130
-100.0%
32.92
USD 4,279
|
130
-100.0%
|
32.92
|
USD 4,279
|
|
|
2020-03-11 |
2020-03-09 |
PS
Planned sale
|
Valentine Karen
See Remarks
|
335
-72.0%
32.08
USD 10,746
|
335
-72.0%
|
32.08
|
USD 10,746
|
|
|
2020-03-11 |
2020-03-09 |
PS
Planned sale
|
Valentine Karen
See Remarks
|
152
-24.6%
31.17
USD 4,738
|
152
-24.6%
|
31.17
|
USD 4,738
|
|
|
2020-02-14 |
2020-02-13 |
PS
Planned sale
|
Reeve Emma
Chief Financial Officer
|
5,521
-100.0%
35.06
USD 193,539
|
5,521
-100.0%
|
35.06
|
USD 193,539
|
|
|
2020-02-14 |
2020-02-13 |
PS
Planned sale
|
Valentine Karen
See Remarks
|
4,473
-100.0%
35.07
USD 156,859
|
4,473
-100.0%
|
35.07
|
USD 156,859
|
|
|
2020-02-14 |
2020-02-12 |
PS
Planned sale
|
Reeve Emma
Chief Financial Officer
|
1,103
-100.0%
35.02
USD 38,624
|
1,103
-100.0%
|
35.02
|
USD 38,624
|
|
|
2020-02-14 |
2020-02-12 |
PS
Planned sale
|
Valentine Karen
See Remarks
|
1,500
-100.0%
35.02
USD 52,527
|
1,500
-100.0%
|
35.02
|
USD 52,527
|
|
|
2020-02-12 |
2020-02-11 |
S
Sale
|
Valentine Karen
See Remarks
|
8,550
-100.0%
35.03
USD 299,507
|
8,550
-100.0%
|
35.03
|
USD 299,507
|
|
|
2020-02-12 |
2020-02-11 |
S
Sale
|
Reeve Emma
Chief Financial Officer
|
1,430
-100.0%
35.04
USD 50,107
|
1,430
-100.0%
|
35.04
|
USD 50,107
|
|
|
2020-02-12 |
2020-02-11 |
S
Sale
|
Reeve Emma
Chief Financial Officer
|
7,212
-100.0%
35.04
USD 252,708
|
7,212
-100.0%
|
35.04
|
USD 252,708
|
|
|
2020-02-12 |
2020-02-10 |
S
Sale
|
Valentine Karen
See Remarks
|
14,096
-100.0%
33.51
USD 472,357
|
14,096
-100.0%
|
33.51
|
USD 472,357
|
|
|
2020-02-12 |
2020-02-10 |
S
Sale
|
Reeve Emma
Chief Financial Officer
|
200
-100.0%
35.00
USD 7,000
|
200
-100.0%
|
35.00
|
USD 7,000
|
|
|
2019-12-16 |
2019-12-13 |
B
Purchase
|
Venrock Healthcare Capital Partners III, L.P.
Large shareholder
|
400,000
+11.1%
34.50
USD 13,800,000
|
400,000
+11.1%
|
34.50
|
USD 13,800,000
|
|
|
2019-12-16 |
2019-12-13 |
B
Purchase
|
EVNIN ANTHONY B
Non-Executive Director
|
400,000
+7.5%
34.50
USD 13,800,000
|
400,000
+7.5%
|
34.50
|
USD 13,800,000
|
|
|
2019-11-08 |
2019-11-06 |
PS
Planned sale
|
Reeve Emma
Chief Financial Officer
|
726
-100.0%
30.84
USD 22,390
|
726
-100.0%
|
30.84
|
USD 22,390
|
|
|
2019-11-08 |
2019-11-06 |
PS
Planned sale
|
Reeve Emma
Chief Financial Officer
|
15,740
-95.6%
29.75
USD 468,260
|
15,740
-95.6%
|
29.75
|
USD 468,260
|
|
|
2019-11-08 |
2019-11-06 |
PS
Planned sale
|
Reeve Emma
Chief Financial Officer
|
11,976
-42.1%
20.01
USD 239,631
|
11,976
-42.1%
|
20.01
|
USD 239,631
|
|
|
2019-11-08 |
2019-11-06 |
PS
Planned sale
|
Reeve Emma
Chief Financial Officer
|
6,188
-17.9%
19.20
USD 118,839
|
6,188
-17.9%
|
19.20
|
USD 118,839
|
|
|
2019-11-08 |
2019-11-06 |
PS
Planned sale
|
Reeve Emma
Chief Financial Officer
|
24,264
-41.2%
18.40
USD 446,518
|
24,264
-41.2%
|
18.40
|
USD 446,518
|
|
|
2019-11-08 |
2019-11-06 |
PS
Planned sale
|
Reeve Emma
Chief Financial Officer
|
4,158
-6.6%
17.59
USD 73,158
|
4,158
-6.6%
|
17.59
|
USD 73,158
|
|
|
2019-11-08 |
2019-11-06 |
PS
Planned sale
|
Reeve Emma
Chief Financial Officer
|
2,574
-3.9%
16.31
USD 41,979
|
2,574
-3.9%
|
16.31
|
USD 41,979
|
|
|
2019-11-08 |
2019-11-06 |
PS
Planned sale
|
Raythatha Jigar
See Remarks
|
350
-2.3%
36.01
USD 12,602
|
350
-2.3%
|
36.01
|
USD 12,602
|
|
|
2019-11-08 |
2019-11-06 |
PS
Planned sale
|
Raythatha Jigar
See Remarks
|
20,200
-56.9%
35.23
USD 711,579
|
20,200
-56.9%
|
35.23
|
USD 711,579
|
|
|
2019-11-08 |
2019-11-06 |
PS
Planned sale
|
Raythatha Jigar
See Remarks
|
12,095
-25.4%
31.32
USD 378,795
|
12,095
-25.4%
|
31.32
|
USD 378,795
|
|
|
2019-11-08 |
2019-11-06 |
PS
Planned sale
|
Raythatha Jigar
See Remarks
|
29,005
-37.9%
30.19
USD 875,528
|
29,005
-37.9%
|
30.19
|
USD 875,528
|
|
|
2019-11-08 |
2019-11-06 |
PS
Planned sale
|
Raythatha Jigar
See Remarks
|
20,550
-21.2%
25.06
USD 514,952
|
20,550
-21.2%
|
25.06
|
USD 514,952
|
|
|
2019-11-08 |
2019-11-06 |
PS
Planned sale
|
Raythatha Jigar
See Remarks
|
3,170
-3.2%
21.20
USD 67,198
|
3,170
-3.2%
|
21.20
|
USD 67,198
|
|
|
2019-11-08 |
2019-11-06 |
PS
Planned sale
|
Raythatha Jigar
See Remarks
|
17,380
-14.8%
20.18
USD 350,727
|
17,380
-14.8%
|
20.18
|
USD 350,727
|
|
|
2019-11-08 |
2019-11-06 |
PS
Planned sale
|
Audia James E
|
7,500
-16.1%
19.11
USD 143,357
|
7,500
-16.1%
|
19.11
|
USD 143,357
|
|
|
2019-11-08 |
2019-11-06 |
PS
Planned sale
|
Audia James E
|
10,500
-18.4%
18.58
USD 195,076
|
10,500
-18.4%
|
18.58
|
USD 195,076
|
|
|
2019-11-08 |
2019-11-06 |
PS
Planned sale
|
Audia James E
|
4,500
-7.3%
17.55
USD 78,978
|
4,500
-7.3%
|
17.55
|
USD 78,978
|
|
|
2019-11-08 |
2019-11-06 |
PS
Planned sale
|
Senderowicz Adrian
Chief Medical Officer
|
5,451
-25.5%
35.11
USD 191,394
|
5,451
-25.5%
|
35.11
|
USD 191,394
|
|
