|
2008-08-06 |
2008-08-06 |
B
Purchase
|
Bengal Acquisition Inc.
See Footnote (1)
Large shareholder
|
1,033,464
+100.0%
4.15
USD 4,288,876
|
1,033,464
+100.0%
|
4.15
|
USD 4,288,876
|
|
|
2008-08-05 |
2008-08-05 |
B
Purchase
|
Stiefel Laboratories, Inc.
See footnote (1)(2)
Large shareholder
|
34,266,494
+inf%
4.15
USD 142,205,950
|
34,266,494
+inf%
|
4.15
|
USD 142,205,950
|
|
|
2006-11-14 |
2006-11-13 |
B
Purchase
|
ERICKSON EDWARD L
Non-Executive Director
|
1,000
+100.0%
7.20
USD 7,200
|
1,000
+100.0%
|
7.20
|
USD 7,200
|
|
|
2006-11-14 |
2006-11-13 |
B
Purchase
|
ERICKSON EDWARD L
Non-Executive Director
|
100
+11.1%
7.26
USD 726
|
100
+11.1%
|
7.26
|
USD 726
|
|
|
2006-11-14 |
2006-11-13 |
B
Purchase
|
ERICKSON EDWARD L
Non-Executive Director
|
300
+50.0%
7.25
USD 2,175
|
300
+50.0%
|
7.25
|
USD 2,175
|
|
|
2006-11-14 |
2006-11-13 |
B
Purchase
|
ERICKSON EDWARD L
Non-Executive Director
|
600
+inf%
7.23
USD 4,338
|
600
+inf%
|
7.23
|
USD 4,338
|
|
|
2006-09-27 |
2006-09-27 |
B
Purchase
|
Jacey Charles F Jr
Non-Executive Director
|
300
+100.0%
6.40
USD 1,920
|
300
+100.0%
|
6.40
|
USD 1,920
|
|
|
2006-08-10 |
2006-08-09 |
B
Purchase
|
CAUWENBERGH GEERT
Chief Executive Officer
Executive Director
|
1,000
+10.0%
5.44
USD 5,437
|
1,000
+10.0%
|
5.44
|
USD 5,437
|
|
|
2006-08-10 |
2006-08-09 |
PP
Planned purchase
|
CAUWENBERGH GEERT
Chief Executive Officer
Executive Director
|
600
+0.1%
5.44
USD 3,262
|
600
+0.1%
|
5.44
|
USD 3,262
|
|
|
2006-08-10 |
2006-08-09 |
B
Purchase
|
CAUWENBERGH GEERT
Chief Executive Officer
Executive Director
|
400
+0.1%
5.42
USD 2,168
|
400
+0.1%
|
5.42
|
USD 2,168
|
|
|
2006-06-16 |
2006-06-16 |
B
Purchase
|
CAMPBELL ROBERT E
Non-Executive Director
|
3,000
+100.0%
5.92
USD 17,751
|
3,000
+100.0%
|
5.92
|
USD 17,751
|
|
|
2006-05-19 |
2006-05-19 |
B
Purchase
|
CAUWENBERGH GEERT
Chief Executive Officer
Executive Director
|
4,000
+100.0%
6.17
USD 24,680
|
4,000
+100.0%
|
6.17
|
USD 24,680
|
|
|
2006-05-19 |
2006-05-19 |
B
Purchase
|
CAUWENBERGH GEERT
Chief Executive Officer
Executive Director
|
1,000
+0.2%
6.17
USD 6,166
|
1,000
+0.2%
|
6.17
|
USD 6,166
|
|
|
2006-03-15 |
2006-03-15 |
PP
Planned purchase
|
CAUWENBERGH GEERT
Chief Executive Officer
Executive Director
|
1,300
+0.3%
9.25
USD 12,022
|
1,300
+0.3%
|
9.25
|
USD 12,022
|
|
|
2006-03-15 |
2006-03-15 |
B
Purchase
|
CAUWENBERGH GEERT
Chief Executive Officer
Executive Director
|
700
+0.1%
9.25
USD 6,475
|
700
+0.1%
|
9.25
|
USD 6,475
|
|
|
2006-03-06 |
2006-03-06 |
B
Purchase
|
CAMPBELL ROBERT E
Non-Executive Director
|
1,000
+50.0%
9.97
USD 9,970
|
1,000
+50.0%
|
9.97
|
USD 9,970
|
|
|
2005-03-14 |
2005-03-11 |
B
Purchase
|
CAUWENBERGH GEERT
Chief Executive Officer
Executive Director
|
200
+5.3%
14.47
USD 2,894
|
200
+5.3%
|
14.47
|
USD 2,894
|
|
|
2005-03-14 |
2005-03-11 |
B
Purchase
|
CAUWENBERGH GEERT
Chief Executive Officer
Executive Director
|
1,300
+52.0%
14.34
USD 18,642
|
1,300
+52.0%
|
14.34
|
USD 18,642
|
|
|
2005-03-14 |
2005-03-11 |
PP
Planned purchase
|
CAUWENBERGH GEERT
Chief Executive Officer
Executive Director
|
100
+0.0%
14.80
USD 1,480
|
100
+0.0%
|
14.80
|
USD 1,480
|
|
|
2005-03-14 |
2005-03-11 |
B
Purchase
|
CAUWENBERGH GEERT
Chief Executive Officer
Executive Director
|
100
+0.0%
14.79
USD 1,479
|
100
+0.0%
|
14.79
|
USD 1,479
|
|
|
2005-03-14 |
2005-03-11 |
B
Purchase
|
CAUWENBERGH GEERT
Chief Executive Officer
Executive Director
|
100
+0.0%
14.78
USD 1,478
|
100
+0.0%
|
14.78
|
USD 1,478
|
|
|
2005-03-14 |
2005-03-11 |
B
Purchase
|
CAUWENBERGH GEERT
Chief Executive Officer
Executive Director
|
1,200
+0.2%
14.77
USD 17,724
|
1,200
+0.2%
|
14.77
|
USD 17,724
|
|
|
2005-03-09 |
2005-03-08 |
PP
Planned purchase
|
VANLENT ANNE
Exec. V.P., CFO and Treasurer
Officer
|
2,000
+1.8%
14.47
USD 28,930
|
2,000
+1.8%
|
14.47
|
USD 28,930
|
|
|
2005-03-03 |
2005-02-15 |
S
Sale
|
SIMON NICHOLAS J III
Non-Executive Director
|
384,236
-16.5%
19.50
USD 7,492,602
|
384,236
-16.5%
|
19.50
|
USD 7,492,602
|
|
|
2005-03-03 |
2005-02-15 |
S
Sale
|
EVNIN LUKE
See Remarks
|
384,236
-16.5%
19.50
USD 7,492,602
|
384,236
-16.5%
|
19.50
|
USD 7,492,602
|
|
|
2005-03-03 |
2005-02-15 |
S
Sale
|
MPM BIOVENTURES III QP LP
See Remarks
|
384,236
-16.5%
19.50
USD 7,492,602
|
384,236
-16.5%
|
19.50
|
USD 7,492,602
|
|
|
2005-02-17 |
2005-02-15 |
S
Sale
|
AKKARAJU SRINIVAS
Non-Executive Director
|
380,497
-16.4%
18.33
USD 6,974,510
|
380,497
-16.4%
|
18.33
|
USD 6,974,510
|
|
|
2005-02-17 |
2005-02-15 |
S
Sale
|
JP MORGAN PARTNERS BHCA LP
Large shareholder
|
3,682
-16.4%
18.33
USD 67,491
|
3,682
-16.4%
|
18.33
|
USD 67,491
|
|
|
2005-02-17 |
2005-02-15 |
S
Sale
|
JP MORGAN PARTNERS BHCA LP
Large shareholder
|
9,068
-16.4%
18.33
USD 166,216
|
9,068
-16.4%
|
18.33
|
USD 166,216
|
|
|
2005-02-17 |
2005-02-15 |
S
Sale
|
JP MORGAN PARTNERS BHCA LP
Large shareholder
|
33,018
-16.4%
18.33
USD 605,220
|
33,018
-16.4%
|
18.33
|
USD 605,220
|
|
|
2005-02-17 |
2005-02-15 |
S
Sale
|
JP MORGAN PARTNERS BHCA LP
Large shareholder
|
65,168
-16.4%
18.33
USD 1,194,529
|
65,168
-16.4%
|
18.33
|
USD 1,194,529
|
|
|
2005-02-17 |
2005-02-15 |
S
Sale
|
JP MORGAN PARTNERS BHCA LP
Large shareholder
|
380,497
-16.4%
18.33
USD 6,974,510
|
380,497
-16.4%
|
18.33
|
USD 6,974,510
|
|
|
2005-02-17 |
2005-02-15 |
S
Sale
|
PERSEUS SOROS BIOPHARMACEUTICAL FUND LP
See footnote (2)
|
430,004
-15.6%
19.50
USD 8,385,078
|
430,004
-15.6%
|
19.50
|
USD 8,385,078
|
|
|
2005-02-15 |
2005-02-15 |
S
Sale
|
JOHNSON & JOHNSON
Large shareholder
|
694,327
-15.6%
19.50
USD 13,539,377
|
694,327
-15.6%
|
19.50
|
USD 13,539,377
|
|
|
2005-01-04 |
2004-12-30 |
B
Purchase
|
JP MORGAN PARTNERS BHCA LP
Large shareholder
|
147,134
+inf%
7.94
USD 1,168,244
|
147,134
+inf%
|
7.94
|
USD 1,168,244
|
|
|
2005-01-04 |
2004-12-30 |
S
Sale
|
JP MORGAN PARTNERS BHCA LP
Large shareholder
|
147,134
-6.0%
7.94
USD 1,168,244
|
147,134
-6.0%
|
7.94
|
USD 1,168,244
|
|
|
2004-12-30 |
2004-12-30 |
PS
Planned sale
|
BRISTOW ALBERT
General Counsel and Secretary
Officer
|
500
-85.0%
16.25
USD 8,125
|
500
-85.0%
|
16.25
|
USD 8,125
|
|
|
2004-12-30 |
2004-12-29 |
PS
Planned sale
|
BRISTOW ALBERT
General Counsel and Secretary
Officer
|
500
-85.0%
16.38
USD 8,190
|
500
-85.0%
|
16.38
|
USD 8,190
|
|
|
2004-12-30 |
2004-12-29 |
PS
Planned sale
|
BRISTOW ALBERT
General Counsel and Secretary
Officer
|
1,000
-63.0%
16.35
USD 16,350
|
1,000
-63.0%
|
16.35
|
USD 16,350
|
|
|
2004-12-30 |
2004-12-29 |
PS
Planned sale
|
BRISTOW ALBERT
General Counsel and Secretary
Officer
|
500
-23.9%
16.33
USD 8,165
|
500
-23.9%
|
16.33
|
USD 8,165
|
|
|
2004-12-30 |
2004-12-29 |
PS
Planned sale
|
BRISTOW ALBERT
General Counsel and Secretary
Officer
|
500
-19.3%
16.32
USD 8,160
|
500
-19.3%
|
16.32
|
USD 8,160
|
|
|
2004-12-28 |
2004-12-28 |
B
Purchase
|
CAMPBELL ROBERT E
Non-Executive Director
|
2,000
+inf%
16.25
USD 32,500
|
2,000
+inf%
|
16.25
|
USD 32,500
|
|
|
2004-12-22 |
2004-12-20 |
S
Sale
|
MPM BIOVENTURES III QP LP
Large shareholder
|
10,000
-0.4%
17.90
USD 179,001
|
10,000
-0.4%
|
17.90
|
USD 179,001
|
|
|
2004-12-22 |
2004-12-20 |
S
Sale
|
SIMON NICHOLAS J III
Non-Executive Director
Large shareholder
|
10,000
-0.4%
17.90
USD 179,001
|
10,000
-0.4%
|
17.90
|
USD 179,001
|
|
|
2004-12-22 |
2004-12-20 |
S
Sale
|
EVNIN LUKE
Large shareholder
|
10,000
-0.4%
17.90
USD 179,001
|
10,000
-0.4%
|
17.90
|
USD 179,001
|
|
|
2004-08-18 |
2004-08-17 |
B
Purchase
|
VANLENT ANNE
Exec. V.P., CFO and Treasurer
Officer
|
1,000
+inf%
10.18
USD 10,180
|
1,000
+inf%
|
10.18
|
USD 10,180
|
|
|
2004-08-16 |
2004-08-13 |
B
Purchase
|
CAUWENBERGH GEERT
Chief Executive Officer
Executive Director
|
1,500
+150.0%
10.70
USD 16,050
|
1,500
+150.0%
|
10.70
|
USD 16,050
|
|
|
2004-08-16 |
2004-08-13 |
PP
Planned purchase
|
CAUWENBERGH GEERT
Chief Executive Officer
Executive Director
|
1,000
+0.2%
10.16
USD 10,160
|
1,000
+0.2%
|
10.16
|
USD 10,160
|
|
|
2004-05-06 |
2004-05-04 |
B
Purchase
|
CAUWENBERGH GEERT
Chief Executive Officer
Executive Director
|
1,000
+inf%
15.00
USD 15,000
|
1,000
+inf%
|
15.00
|
USD 15,000
|
|
|
2004-05-06 |
2004-05-04 |
B
Purchase
|
CAUWENBERGH GEERT
Chief Executive Officer
Executive Director
|
1,000
+inf%
15.00
USD 15,000
|
1,000
+inf%
|
15.00
|
USD 15,000
|
|
|
2004-05-06 |
2004-05-04 |
B
Purchase
|
CAUWENBERGH GEERT
Chief Executive Officer
Executive Director
|
1,000
+inf%
15.00
USD 15,000
|
1,000
+inf%
|
15.00
|
USD 15,000
|
|
|
2004-05-05 |
2004-05-04 |
B
Purchase
|
EVNIN LUKE
Large shareholder
|
200,000
+9.3%
15.00
USD 3,000,000
|
200,000
+9.3%
|
15.00
|
USD 3,000,000
|
|
|
2004-05-05 |
2004-05-04 |
B
Purchase
|
SIMON NICHOLAS J III
Large shareholder
|
200,000
+9.3%
15.00
USD 3,000,000
|
200,000
+9.3%
|
15.00
|
USD 3,000,000
|
|
|
2004-05-05 |
2004-05-04 |
B
Purchase
|
MPM BIOVENTURES III QP LP
Large shareholder
|
200,000
+9.3%
15.00
USD 3,000,000
|
200,000
+9.3%
|
15.00
|
USD 3,000,000
|
|
