|
2009-02-05 |
2009-02-04 |
S
Sale
|
BARKER SAM L
Non-Executive Director
|
20,000
-100.0%
0.04
USD 720
|
20,000
-100.0%
|
0.04
|
USD 720
|
|
|
2009-02-05 |
2009-02-04 |
S
Sale
|
BARKER SAM L
Non-Executive Director
|
6,000
-100.0%
0.04
USD 210
|
6,000
-100.0%
|
0.04
|
USD 210
|
|
|
2008-11-04 |
2008-10-31 |
S
Sale
|
HENOS MICHAEL A
Non-Executive Director
|
20,000
-100.0%
0.07
USD 1,400
|
20,000
-100.0%
|
0.07
|
USD 1,400
|
|
|
2008-11-04 |
2008-10-31 |
S
Sale
|
HENOS MICHAEL A
Non-Executive Director
|
10,000
-33.3%
0.07
USD 650
|
10,000
-33.3%
|
0.07
|
USD 650
|
|
|
2008-11-04 |
2008-10-31 |
S
Sale
|
HENOS MICHAEL A
Non-Executive Director
|
70,000
-70.0%
0.06
USD 3,850
|
70,000
-70.0%
|
0.06
|
USD 3,850
|
|
|
2008-02-11 |
2008-02-08 |
B
Purchase
|
BRYSON VAUGHN D
Non-Executive Director
|
50,000
+162.6%
0.64
USD 32,000
|
50,000
+162.6%
|
0.64
|
USD 32,000
|
|
|
2008-02-01 |
2008-01-25 |
B
Purchase
|
BARKER SAM L
Non-Executive Director
|
20,000
+inf%
0.39
USD 7,800
|
20,000
+inf%
|
0.39
|
USD 7,800
|
|
|
2008-02-01 |
2008-01-25 |
B
Purchase
|
BARKER SAM L
Non-Executive Director
|
5,000
+500.0%
0.39
USD 1,950
|
5,000
+500.0%
|
0.39
|
USD 1,950
|
|
|
2008-02-15 |
2008-01-22 |
S
Sale
|
BRYSON VAUGHN D
Non-Executive Director
|
3,386
-4.2%
0.39
USD 1,321
|
3,386
-4.2%
|
0.39
|
USD 1,321
|
|
|
2007-12-31 |
2007-12-28 |
S
Sale
|
BRYSON VAUGHN D
Non-Executive Director
|
13,130
-29.9%
0.38
USD 5,034
|
13,130
-29.9%
|
0.38
|
USD 5,034
|
|
|
2007-12-31 |
2007-12-28 |
S
Sale
|
BRYSON VAUGHN D
Non-Executive Director
|
11,603
-20.9%
0.38
USD 4,431
|
11,603
-20.9%
|
0.38
|
USD 4,431
|
|
|
2007-12-31 |
2007-12-27 |
S
Sale
|
BRYSON VAUGHN D
Non-Executive Director
|
48,732
-46.8%
0.40
USD 19,493
|
48,732
-46.8%
|
0.40
|
USD 19,493
|
|
|
2007-12-31 |
2007-12-26 |
S
Sale
|
BRYSON VAUGHN D
Non-Executive Director
|
2,440
-2.3%
0.40
USD 976
|
2,440
-2.3%
|
0.40
|
USD 976
|
|
|
2007-12-26 |
2007-12-20 |
S
Sale
|
BRYSON VAUGHN D
Non-Executive Director
|
7,657
-6.7%
0.43
USD 3,293
|
7,657
-6.7%
|
0.43
|
USD 3,293
|
|
|
2007-12-07 |
2007-12-06 |
S
Sale
|
HENOS MICHAEL A
Non-Executive Director
|
16,799
-14.4%
0.49
USD 8,232
|
16,799
-14.4%
|
0.49
|
USD 8,232
|
|
|
2007-12-07 |
2007-12-06 |
S
Sale
|
HENOS MICHAEL A
Non-Executive Director
|
10,337
-8.1%
0.48
USD 4,962
|
10,337
-8.1%
|
0.48
|
USD 4,962
|
|
|
2007-12-07 |
2007-12-06 |
S
Sale
|
HENOS MICHAEL A
Non-Executive Director
|
2,864
-2.2%
0.47
USD 1,346
|
2,864
-2.2%
|
0.47
|
USD 1,346
|
|
|
2007-11-29 |
2007-11-28 |
S
Sale
|
ATTICUS MANAGEMENT LLC
Large shareholder
|
1,587,000
-36.2%
0.50
USD 793,500
|
1,587,000
-36.2%
|
0.50
|
USD 793,500
|
|
|
2007-11-29 |
2007-11-28 |
S
Sale
|
ATTICUS MANAGEMENT LLC
Large shareholder
|
85,649
-1.9%
0.49
USD 41,831
|
85,649
-1.9%
|
0.49
|
USD 41,831
|
|
|
2007-11-29 |
2007-11-28 |
S
Sale
|
ATTICUS MANAGEMENT LLC
Large shareholder
|
7,300
-0.2%
0.63
USD 4,633
|
7,300
-0.2%
|
0.63
|
USD 4,633
|
|
|
2007-11-29 |
2007-11-27 |
S
Sale
|
ATTICUS MANAGEMENT LLC
Large shareholder
|
163,703
-3.5%
0.64
USD 104,475
|
163,703
-3.5%
|
0.64
|
USD 104,475
|
|
|
2007-11-29 |
2007-11-27 |
S
Sale
|
ATTICUS MANAGEMENT LLC
Large shareholder
|
25,000
-0.5%
0.71
USD 17,645
|
25,000
-0.5%
|
0.71
|
USD 17,645
|
|
|
2007-11-29 |
2007-11-27 |
S
Sale
|
ATTICUS MANAGEMENT LLC
Large shareholder
|
50,000
-1.1%
0.64
USD 31,875
|
50,000
-1.1%
|
0.64
|
USD 31,875
|
|
|
2007-11-29 |
2007-11-27 |
S
Sale
|
ATTICUS MANAGEMENT LLC
Large shareholder
|
44,338
-0.9%
0.63
USD 27,951
|
44,338
-0.9%
|
0.63
|
USD 27,951
|
|
|
2007-09-05 |
2007-08-29 |
S
Sale
|
BRYSON VAUGHN D
Non-Executive Director
|
55,518
-32.7%
2.15
USD 119,364
|
55,518
-32.7%
|
2.15
|
USD 119,364
|
|
|
2007-04-02 |
2007-04-02 |
B
Purchase
|
SCOTT ROBERT A
Exec VP Research & Development
Officer
|
36,000
+253.4%
2.77
USD 99,576
|
36,000
+253.4%
|
2.77
|
USD 99,576
|
|
|
2006-09-05 |
2006-08-31 |
B
Purchase
|
Barker Samuel L
Non-Executive Director
|
300
+42.9%
14.13
USD 4,239
|
300
+42.9%
|
14.13
|
USD 4,239
|
|
|
2006-09-05 |
2006-08-31 |
B
Purchase
|
Barker Samuel L
Non-Executive Director
|
700
+inf%
14.10
USD 9,870
|
700
+inf%
|
14.10
|
USD 9,870
|
|
|
2006-07-03 |
2006-06-30 |
B
Purchase
|
BRYSON VAUGHN D
Non-Executive Director
|
17,132
+11.2%
13.06
USD 223,794
|
17,132
+11.2%
|
13.06
|
USD 223,794
|
|
|
2006-07-03 |
2006-06-29 |
B
Purchase
|
BRYSON VAUGHN D
Non-Executive Director
|
22,868
+17.6%
12.97
USD 296,660
|
22,868
+17.6%
|
12.97
|
USD 296,660
|
|
|
2006-05-31 |
2006-05-30 |
B
Purchase
|
BRYSON VAUGHN D
Non-Executive Director
|
20,000
+18.2%
13.87
USD 277,474
|
20,000
+18.2%
|
13.87
|
USD 277,474
|
|
|
2006-05-25 |
2006-05-24 |
B
Purchase
|
PAPPAS ARTHUR M
Non-Executive Director
|
1,000
+7.1%
12.97
USD 12,969
|
1,000
+7.1%
|
12.97
|
USD 12,969
|
|
|
2006-05-24 |
2006-05-22 |
B
Purchase
|
PAPPAS ARTHUR M
Non-Executive Director
|
3,000
+27.3%
13.52
USD 40,569
|
3,000
+27.3%
|
13.52
|
USD 40,569
|
|
|
2006-05-01 |
2006-04-27 |
B
Purchase
|
PAPPAS ARTHUR M
Non-Executive Director
|
3,000
+37.5%
14.03
USD 42,092
|
3,000
+37.5%
|
14.03
|
USD 42,092
|
|
|
2006-03-27 |
2006-03-24 |
B
Purchase
|
PAPPAS ARTHUR M
Non-Executive Director
|
1,000
+14.3%
15.83
USD 15,827
|
1,000
+14.3%
|
15.83
|
USD 15,827
|
|
|
2006-03-20 |
2006-03-16 |
S
Sale
|
SCOTT WILLIAM A
Non-Executive Director
|
1,200
-100.0%
15.33
USD 18,396
|
1,200
-100.0%
|
15.33
|
USD 18,396
|
|
|
2006-03-20 |
2006-03-16 |
S
Sale
|
SCOTT WILLIAM A
Non-Executive Director
|
8,800
-88.0%
15.32
USD 134,816
|
8,800
-88.0%
|
15.32
|
USD 134,816
|
|
|
2006-03-20 |
2006-03-16 |
S
Sale
|
SCOTT WILLIAM A
Non-Executive Director
|
2,000
-16.7%
15.26
USD 30,520
|
2,000
-16.7%
|
15.26
|
USD 30,520
|
|
|
2006-03-20 |
2006-03-16 |
S
Sale
|
SCOTT WILLIAM A
Non-Executive Director
|
21,700
-64.4%
15.30
USD 332,010
|
21,700
-64.4%
|
15.30
|
USD 332,010
|
|
|
2006-03-20 |
2006-03-16 |
S
Sale
|
SCOTT WILLIAM A
Non-Executive Director
|
8,100
-19.4%
15.35
USD 124,335
|
8,100
-19.4%
|
15.35
|
USD 124,335
|
|
|
2006-02-01 |
2006-02-01 |
B
Purchase
|
ATTICUS MANAGEMENT LLC
Large shareholder
|
225,000
+5.0%
17.23
USD 3,876,750
|
225,000
+5.0%
|
17.23
|
USD 3,876,750
|
|
|
2006-02-01 |
2006-01-31 |
B
Purchase
|
ATTICUS MANAGEMENT LLC
Large shareholder
|
250,000
+5.8%
16.94
USD 4,235,000
|
250,000
+5.8%
|
16.94
|
USD 4,235,000
|
|
|
2006-02-01 |
2006-01-30 |
B
Purchase
|
ATTICUS MANAGEMENT LLC
Large shareholder
|
125,000
+3.0%
16.86
USD 2,107,500
|
125,000
+3.0%
|
16.86
|
USD 2,107,500
|
|
|
2005-12-29 |
2005-12-28 |
S
Sale
|
ALEXANDER R WAYNE
Non-Executive Director
|
25,000
-6.9%
20.09
USD 502,135
|
25,000
-6.9%
|
20.09
|
USD 502,135
|
|
|
2005-12-29 |
2005-12-28 |
S
Sale
|
MEDFORD RUSSELL M
President & CEO
Executive Director
|
150,000
-28.6%
20.02
USD 3,003,000
|
150,000
-28.6%
|
20.02
|
USD 3,003,000
|
|
|
2005-12-29 |
2005-12-28 |
S
Sale
|
SCOTT ROBERT A
Sr VP Clinical Dev & RA
Officer
|
3,900
-100.0%
20.01
USD 78,026
|
3,900
-100.0%
|
20.01
|
USD 78,026
|
|
|
2005-12-29 |
2005-12-28 |
S
Sale
|
SCOTT ROBERT A
Sr VP Clinical Dev & RA
Officer
|
16,100
-80.5%
20.01
USD 322,106
|
16,100
-80.5%
|
20.01
|
USD 322,106
|
|
|
2005-12-29 |
2005-12-27 |
S
Sale
|
COLONNESE MARK P
Sr VP Finance & Admin & CFO
Officer
|
29,400
-100.0%
21.35
USD 627,690
|
29,400
-100.0%
|
21.35
|
USD 627,690
|
|
|
2005-12-29 |
2005-12-27 |
S
Sale
|
COLONNESE MARK P
Sr VP Finance & Admin & CFO
Officer
|
20,000
-100.0%
21.35
USD 427,000
|
20,000
-100.0%
|
21.35
|
USD 427,000
|
|
|
2005-12-29 |
2005-12-27 |
S
Sale
|
COLONNESE MARK P
Sr VP Finance & Admin & CFO
Officer
|
50,600
-100.0%
21.35
USD 1,080,310
|
50,600
-100.0%
|
21.35
|
USD 1,080,310
|
|
|
2005-10-31 |
2005-10-27 |
B
Purchase
|
ATTICUS CAPITAL LLC
Other reporting person
Large shareholder
|
30,000
+0.7%
15.27
USD 458,100
|
30,000
+0.7%
|
15.27
|
USD 458,100
|
|
|
2005-10-26 |
2005-10-24 |
B
Purchase
|
ATTICUS CAPITAL LLC
Large shareholder
|
50,000
+1.2%
15.30
USD 765,000
|
50,000
+1.2%
|
15.30
|
USD 765,000
|
|
|
2005-10-24 |
2005-10-21 |
B
Purchase
|
ATTICUS CAPITAL LLC
Large shareholder
|
40,000
+1.0%
15.16
USD 606,400
|
40,000
+1.0%
|
15.16
|
USD 606,400
|
|
|
2005-10-24 |
2005-10-20 |
B
Purchase
|
ATTICUS CAPITAL LLC
Large shareholder
|
40,000
+1.0%
15.55
USD 622,000
|
40,000
+1.0%
|
15.55
|
USD 622,000
|
|
|
2005-10-18 |
2005-10-17 |
B
Purchase
|
ATTICUS CAPITAL LLC
Large shareholder
|
40,000
+1.0%
15.93
USD 637,200
|
40,000
+1.0%
|
15.93
|
USD 637,200
|
|
|
2005-10-18 |
2005-10-14 |
B
Purchase
|
ATTICUS CAPITAL LLC
Large shareholder
|
50,000
+1.3%
15.97
USD 798,500
|
50,000
+1.3%
|
15.97
|
USD 798,500
|
|
|
2005-06-16 |
2005-06-14 |
B
Purchase
|
ATTICUS CAPITAL LLC
Large shareholder
|
50,000
+1.3%
16.32
USD 816,000
|
50,000
+1.3%
|
16.32
|
USD 816,000
|
|
|
2005-06-14 |
2005-06-10 |
B
Purchase
|
ATTICUS CAPITAL LLC
Large shareholder
|
50,000
+1.3%
16.44
USD 822,000
|
50,000
+1.3%
|
16.44
|
USD 822,000
|
|
|
2005-06-10 |
2005-06-09 |
B
Purchase
|
ATTICUS CAPITAL LLC
Large shareholder
|
50,000
+1.3%
15.58
USD 779,000
|
50,000
+1.3%
|
15.58
|
USD 779,000
|
|
|
2005-06-10 |
2005-06-08 |
B
Purchase
|
ATTICUS CAPITAL LLC
Large shareholder
|
50,000
+1.4%
15.59
USD 779,500
|
50,000
+1.4%
|
15.59
|
USD 779,500
|
|
|
2005-06-01 |
2005-05-27 |
B
Purchase
|
ATTICUS CAPITAL LLC
Large shareholder
|
50,000
+1.4%
14.63
USD 731,500
|
50,000
+1.4%
|
14.63
|
USD 731,500
|
|
|
2005-05-26 |
2005-05-25 |
B
Purchase
|
ATTICUS CAPITAL LLC
Large shareholder
|
50,000
+1.4%
14.66
USD 733,000
|
50,000
+1.4%
|
14.66
|
USD 733,000
|
|
|
2005-05-26 |
2005-05-24 |
B
Purchase
|
ATTICUS CAPITAL LLC
Large shareholder
|
50,000
+1.4%
14.93
USD 746,500
|
50,000
+1.4%
|
14.93
|
USD 746,500
|
|
|
2005-05-19 |
2005-05-18 |
B
Purchase
|
ATTICUS CAPITAL LLC
Large shareholder
|
28,900
+0.8%
14.60
USD 421,940
|
28,900
+0.8%
|
14.60
|
USD 421,940
|
|
|
2005-05-19 |
2005-05-17 |
B
Purchase
|
ATTICUS CAPITAL LLC
Large shareholder
|
21,000
+0.6%
14.66
USD 307,860
|
21,000
+0.6%
|
14.66
|
USD 307,860
|
|
|
2005-05-10 |
2005-05-06 |
B
Purchase
|
ATTICUS CAPITAL LLC
Large shareholder
|
100,000
+3.0%
13.69
USD 1,369,000
|
100,000
+3.0%
|
13.69
|
USD 1,369,000
|
|
|
2005-05-06 |
2005-05-05 |
B
Purchase
|
ATTICUS CAPITAL LLC
Large shareholder
|
50,000
+1.5%
12.17
USD 608,500
|
50,000
+1.5%
|
12.17
|
USD 608,500
|
|
|
2005-05-06 |
2005-05-04 |
B
Purchase
|
ATTICUS CAPITAL LLC
Large shareholder
|
75,000
+2.4%
11.76
USD 882,000
|
75,000
+2.4%
|
11.76
|
USD 882,000
|
|
|
2005-04-01 |
2005-03-30 |
B
Purchase
|
ATTICUS CAPITAL LLC
Large shareholder
|
91,300
+3.0%
12.99
USD 1,185,987
|
91,300
+3.0%
|
12.99
|
USD 1,185,987
|
|
|
2005-03-30 |
2005-03-28 |
B
Purchase
|
ATTICUS CAPITAL LLC
Large shareholder
|
100,000
+3.4%
13.83
USD 1,383,000
|
100,000
+3.4%
|
13.83
|
USD 1,383,000
|
|
|
2005-03-28 |
2005-03-24 |
B
Purchase
|
ATTICUS CAPITAL LLC
Large shareholder
|
129,800
+4.6%
14.07
USD 1,826,286
|
129,800
+4.6%
|
14.07
|
USD 1,826,286
|
|
|
2005-03-23 |
2005-03-22 |
B
Purchase
|
ATTICUS CAPITAL LLC
Large shareholder
|
150,000
+5.7%
13.62
USD 2,043,000
|
150,000
+5.7%
|
13.62
|
USD 2,043,000
|
|
|
2005-02-28 |
2005-02-24 |
S
Sale
|
MEDFORD RUSSELL M
President & CEO
Executive Director
|
100,000
-16.7%
17.51
USD 1,751,000
|
100,000
-16.7%
|
17.51
|
USD 1,751,000
|
|
|
2005-02-28 |
2005-02-24 |
S
Sale
|
SCOTT ROBERT A
Sr VP Clinical Dev/Reg Affairs
Officer
|
30,000
-88.5%
17.51
USD 525,300
|
30,000
-88.5%
|
17.51
|
USD 525,300
|
|
|
2005-02-28 |
2005-02-24 |
S
Sale
|
COLONNESE MARK P
Sr VP Finance/Admin & CFO
Officer
|
39,400
-100.0%
17.51
USD 689,894
|
39,400
-100.0%
|
17.51
|
USD 689,894
|
|
