|
2023-10-31 |
2023-10-18 |
B
Purchase
|
Israel Biotech Fund I, L.P.
Large shareholder
|
658,858
0.00
USD 0
|
658,858
|
0.00
|
USD 0
|
|
|
2023-10-31 |
2023-10-18 |
B
Purchase
|
Israel Biotech Fund I, L.P.
Large shareholder
|
658,858
0.00
USD 0
|
658,858
|
0.00
|
USD 0
|
|
|
2020-03-16 |
2020-03-13 |
S
Sale
|
APPEL RONI
Non-Executive Director
|
2,401
-18.6%
0.55
USD 1,321
|
2,401
-18.6%
|
0.55
|
USD 1,321
|
|
|
2020-03-16 |
2020-03-12 |
S
Sale
|
APPEL RONI
Non-Executive Director
|
200
-1.5%
0.58
USD 116
|
200
-1.5%
|
0.58
|
USD 116
|
|
|
2020-03-16 |
2020-03-11 |
S
Sale
|
APPEL RONI
Non-Executive Director
|
399
-3.0%
0.67
USD 267
|
399
-3.0%
|
0.67
|
USD 267
|
|
|
2019-04-11 |
2019-04-10 |
B
Purchase
|
APPEL RONI
|
3,000
+28.6%
3.80
USD 11,391
|
3,000
+28.6%
|
3.80
|
USD 11,391
|
|
|
2018-11-07 |
2018-11-05 |
S
Sale
|
PETIT ROBERT
Chief Scientific Officer
Officer
|
3,963
-1.7%
0.58
USD 2,299
|
3,963
-1.7%
|
0.58
|
USD 2,299
|
|
|
2018-11-05 |
2018-11-02 |
S
Sale
|
PETIT ROBERT
Chief Scientific Officer
Officer
|
8,491
-3.5%
0.56
USD 4,755
|
8,491
-3.5%
|
0.56
|
USD 4,755
|
|
|
2018-09-13 |
2018-09-11 |
B
Purchase
|
APPEL RONI
Non-Executive Director
|
33,333
+26.9%
1.20
USD 40,000
|
33,333
+26.9%
|
1.20
|
USD 40,000
|
|
|
2018-04-03 |
2018-04-02 |
S
Sale
|
PETIT ROBERT
Chief Scientific Officer
|
2,193
-1.0%
1.62
USD 3,553
|
2,193
-1.0%
|
1.62
|
USD 3,553
|
|
|
2018-02-02 |
2018-02-02 |
S
Sale
|
LOMBARDO ANTHONY A
Interim CEO
Officer
|
32
-0.0%
2.93
USD 94
|
32
-0.0%
|
2.93
|
USD 94
|
|
|
2018-01-03 |
2018-01-03 |
S
Sale
|
Bonstein Sara
Chief Financial Officer
Officer
|
5,224
-2.3%
3.18
USD 16,612
|
5,224
-2.3%
|
3.18
|
USD 16,612
|
|
|
2017-11-06 |
2017-11-06 |
S
Sale
|
Bonstein Sara
Chief Financial Officer
|
3,862
-1.7%
3.30
USD 12,745
|
3,862
-1.7%
|
3.30
|
USD 12,745
|
|
|
2017-11-06 |
2017-11-06 |
S
Sale
|
PETIT ROBERT
Chief Scientific Officer
|
3,723
-1.7%
3.30
USD 12,286
|
3,723
-1.7%
|
3.30
|
USD 12,286
|
|
|
2017-11-02 |
2017-11-02 |
S
Sale
|
LOMBARDO ANTHONY A
Interim CEO
|
24
-0.0%
3.19
USD 77
|
24
-0.0%
|
3.19
|
USD 77
|
|
|
2017-11-02 |
2017-11-02 |
S
Sale
|
PETIT ROBERT
Chief Scientific Officer
|
12,625
-5.3%
3.19
USD 40,274
|
12,625
-5.3%
|
3.19
|
USD 40,274
|
|
|
2017-11-02 |
2017-11-02 |
S
Sale
|
Bonstein Sara
Chief Financial Officer
|
12,734
-5.2%
3.19
USD 40,621
|
12,734
-5.2%
|
3.19
|
USD 40,621
|
|
|
2017-10-12 |
2017-10-11 |
S
Sale
|
ADAGE CAPITAL PARTNERS GP, L.L.C.
Large shareholder
|
600,000
-12.8%
4.30
USD 2,580,000
|
600,000
-12.8%
|
4.30
|
USD 2,580,000
|
|
|
2017-09-26 |
2017-09-26 |
S
Sale
|
ADAGE CAPITAL PARTNERS GP, L.L.C.
Large shareholder
|
300,000
-6.0%
4.00
USD 1,200,000
|
300,000
-6.0%
|
4.00
|
USD 1,200,000
|
|
|
2017-09-26 |
2017-09-25 |
S
Sale
|
ADAGE CAPITAL PARTNERS GP, L.L.C.
Large shareholder
|
405,323
-7.5%
4.38
USD 1,775,315
|
405,323
-7.5%
|
4.38
|
USD 1,775,315
|
|
|
2017-09-26 |
2017-09-22 |
S
Sale
|
ADAGE CAPITAL PARTNERS GP, L.L.C.
Large shareholder
|
534,000
-9.0%
4.68
USD 2,499,120
|
534,000
-9.0%
|
4.68
|
USD 2,499,120
|
|
|
2017-04-03 |
2017-03-31 |
S
Sale
|
PETIT ROBERT
Chief Scientific Officer
|
2,454
-2.0%
8.24
USD 20,221
|
2,454
-2.0%
|
8.24
|
USD 20,221
|
|
|
2017-01-03 |
2016-12-30 |
S
Sale
|
Bonstein Sara
Chief Financial Officer
Officer
|
5,520
-4.2%
7.37
USD 40,682
|
5,520
-4.2%
|
7.37
|
USD 40,682
|
|
|
2016-12-21 |
2016-12-20 |
S
Sale
|
MCKEARN THOMAS J
Non-Executive Director
|
12,316
-15.0%
8.08
USD 99,513
|
12,316
-15.0%
|
8.08
|
USD 99,513
|
|
|
2016-11-02 |
2016-11-02 |
S
Sale
|
PETIT ROBERT
Chief Scientific Officer
Officer
|
2,797
-2.3%
8.32
USD 23,271
|
2,797
-2.3%
|
8.32
|
USD 23,271
|
|
|
2016-11-02 |
2016-11-02 |
S
Sale
|
O'Connor Daniel
Chief Executive Officer
Executive Director
|
8,240
-2.7%
8.32
USD 68,557
|
8,240
-2.7%
|
8.32
|
USD 68,557
|
|
|
2016-10-26 |
2016-10-25 |
S
Sale
|
Mayes, Gregory T.
Chief Business Officer
Executive Director
|
19,162
-15.7%
8.23
USD 157,703
|
19,162
-15.7%
|
8.23
|
USD 157,703
|
|
|
2016-08-10 |
2016-08-09 |
S
Sale
|
BERMAN RICHARD J
Non-Executive Director
|
15,761
-23.7%
15.67
USD 246,975
|
15,761
-23.7%
|
15.67
|
USD 246,975
|
|
|
2016-08-10 |
2016-08-09 |
S
Sale
|
SIDRANSKY DAVID
Non-Executive Director
|
11,404
-12.4%
14.85
USD 169,349
|
11,404
-12.4%
|
14.85
|
USD 169,349
|
|
|
2016-08-10 |
2016-08-08 |
S
Sale
|
BERMAN RICHARD J
Non-Executive Director
|
18,000
-21.3%
15.21
USD 273,780
|
18,000
-21.3%
|
15.21
|
USD 273,780
|
|
|
2016-08-10 |
2016-08-08 |
S
Sale
|
SIDRANSKY DAVID
Non-Executive Director
|
11,404
-11.1%
15.17
USD 172,999
|
11,404
-11.1%
|
15.17
|
USD 172,999
|
|
|
2016-05-13 |
2016-05-13 |
S
Sale
|
MCKEARN THOMAS J
Non-Executive Director
|
4,100
-4.8%
7.45
USD 30,545
|
4,100
-4.8%
|
7.45
|
USD 30,545
|
|
|
2016-05-02 |
2016-05-02 |
S
Sale
|
PETIT ROBERT
Chief Scientific Officer
Officer
|
2,785
-2.2%
7.51
USD 20,915
|
2,785
-2.2%
|
7.51
|
USD 20,915
|
|
|
2016-05-02 |
2016-05-02 |
S
Sale
|
O'Connor Daniel
Chief Executive Officer
Officer
|
8,237
-2.6%
7.51
USD 61,860
|
8,237
-2.6%
|
7.51
|
USD 61,860
|
|
|
2016-04-01 |
2016-03-31 |
S
Sale
|
PETIT ROBERT
Chief Scientific Officer
Officer
|
3,325
-2.5%
9.13
USD 30,357
|
3,325
-2.5%
|
9.13
|
USD 30,357
|
|
|
2016-03-18 |
2016-03-16 |
S
Sale
|
MCKEARN THOMAS J
Non-Executive Director
|
14,000
-14.0%
8.25
USD 115,500
|
14,000
-14.0%
|
8.25
|
USD 115,500
|
|
|
2016-02-25 |
2016-02-24 |
S
Sale
|
Bonstein Sara
Chief Financial Officer
Officer
|
15,037
-15.8%
5.58
USD 83,906
|
15,037
-15.8%
|
5.58
|
USD 83,906
|
|
|
2016-02-01 |
2016-01-29 |
S
Sale
|
PETIT ROBERT
Chief Scientific Officer
Officer
|
3,099
-2.3%
6.88
USD 21,321
|
3,099
-2.3%
|
6.88
|
USD 21,321
|
|
|
2016-02-01 |
2016-01-29 |
S
Sale
|
O'Connor Daniel
Chief Executive Officer
Officer
|
8,818
-2.7%
6.88
USD 60,668
|
8,818
-2.7%
|
6.88
|
USD 60,668
|
|
|
2015-08-24 |
2015-08-24 |
B
Purchase
|
ADAGE CAPITAL PARTNERS GP LLC
Large shareholder
|
12,100
+0.2%
14.47
USD 175,087
|
12,100
+0.2%
|
14.47
|
USD 175,087
|
|
|
2015-08-24 |
2015-08-24 |
B
Purchase
|
ADAGE CAPITAL PARTNERS GP LLC
Large shareholder
|
9,500
+0.2%
13.73
USD 130,435
|
9,500
+0.2%
|
13.73
|
USD 130,435
|
|
|
2015-08-24 |
2015-08-24 |
B
Purchase
|
ADAGE CAPITAL PARTNERS GP LLC
Large shareholder
|
3,400
+0.1%
14.06
USD 47,804
|
3,400
+0.1%
|
14.06
|
USD 47,804
|
|
|
2015-08-24 |
2015-08-24 |
B
Purchase
|
ADAGE CAPITAL PARTNERS GP LLC
Large shareholder
|
20,000
+0.3%
12.90
USD 258,000
|
20,000
+0.3%
|
12.90
|
USD 258,000
|
|
|
2015-08-24 |
2015-08-24 |
B
Purchase
|
ADAGE CAPITAL PARTNERS GP LLC
Large shareholder
|
5,000
+0.1%
13.87
USD 69,350
|
5,000
+0.1%
|
13.87
|
USD 69,350
|
|
|
2015-08-24 |
2015-08-21 |
B
Purchase
|
ADAGE CAPITAL PARTNERS GP LLC
Large shareholder
|
75,000
+1.3%
14.21
USD 1,065,750
|
75,000
+1.3%
|
14.21
|
USD 1,065,750
|
|
|
2015-08-24 |
2015-08-20 |
B
Purchase
|
ADAGE CAPITAL PARTNERS GP LLC
Large shareholder
|
12,000
+0.2%
14.17
USD 170,040
|
12,000
+0.2%
|
14.17
|
USD 170,040
|
|
|
2015-08-24 |
2015-08-20 |
B
Purchase
|
ADAGE CAPITAL PARTNERS GP LLC
Large shareholder
|
13,600
+0.2%
14.31
USD 194,616
|
13,600
+0.2%
|
14.31
|
USD 194,616
|
|
|
2015-08-24 |
2015-08-20 |
B
Purchase
|
ADAGE CAPITAL PARTNERS GP LLC
Large shareholder
|
45,582
+0.8%
14.32
USD 652,734
|
45,582
+0.8%
|
14.32
|
USD 652,734
|
|
|
2015-08-24 |
2015-08-20 |
B
Purchase
|
ADAGE CAPITAL PARTNERS GP LLC
Large shareholder
|
103,818
+1.8%
14.28
USD 1,482,521
|
103,818
+1.8%
|
14.28
|
USD 1,482,521
|
|
|
2015-05-04 |
2015-04-30 |
B
Purchase
|
ADAGE CAPITAL PARTNERS GP LLC
Large shareholder
|
500,000
+9.7%
19.00
USD 9,500,000
|
500,000
+9.7%
|
19.00
|
USD 9,500,000
|
|
|
2015-02-20 |
2015-02-18 |
B
Purchase
|
ADAGE CAPITAL PARTNERS GP LLC
Large shareholder
|
684,762
+15.4%
7.50
USD 5,135,715
|
684,762
+15.4%
|
7.50
|
USD 5,135,715
|
|
|
2014-05-09 |
2014-05-09 |
S
Sale
|
BERMAN RICHARD J
Non-Executive Director
|
7,530
-100.0%
2.63
USD 19,823
|
7,530
-100.0%
|
2.63
|
USD 19,823
|
|
|
2014-05-09 |
2014-05-09 |
S
Sale
|
BERMAN RICHARD J
Non-Executive Director
|
7,000
-48.2%
2.63
USD 18,425
|
7,000
-48.2%
|
2.63
|
USD 18,425
|
|
|
2014-04-02 |
2014-03-31 |
B
Purchase
|
O'Connor Daniel
Chief Executive Officer
Executive Director
|
3,333
+1.1%
3.00
USD 9,999
|
3,333
+1.1%
|
3.00
|
USD 9,999
|
|
|
2013-10-29 |
2013-10-24 |
B
Purchase
|
PATTON JAMES P
Non-Executive Director
|
25,000
+39.7%
4.00
USD 100,000
|
25,000
+39.7%
|
4.00
|
USD 100,000
|
|
|
2013-10-29 |
2013-10-24 |
B
Purchase
|
APPEL RONI
Non-Executive Director
|
12,500
+28.1%
4.00
USD 50,000
|
12,500
+28.1%
|
4.00
|
USD 50,000
|
|
|
2013-10-28 |
2013-10-24 |
B
Purchase
|
PETIT ROBERT
Chief Scientific Officer
Officer
|
12,800
+367.1%
4.00
USD 51,200
|
12,800
+367.1%
|
4.00
|
USD 51,200
|
|
|
2013-10-28 |
2013-10-24 |
B
Purchase
|
Rosenblum Mark J
Chief Financial Officer
Officer
|
12,000
+146.4%
4.00
USD 48,000
|
12,000
+146.4%
|
4.00
|
USD 48,000
|
|
|
2013-10-28 |
2013-10-24 |
B
Purchase
|
O'Connor Daniel
Chief Executive Officer
Executive Director
|
13,500
+28.3%
4.00
USD 54,000
|
13,500
+28.3%
|
4.00
|
USD 54,000
|
|
|
2013-07-10 |
2012-11-23 |
S
Sale
|
BERMAN RICHARD J
Non-Executive Director
|
100,000
-100.0%
0.04
USD 3,500
|
100,000
-100.0%
|
0.04
|
USD 3,500
|
|
|
2013-07-10 |
2012-11-21 |
S
Sale
|
BERMAN RICHARD J
Non-Executive Director
|
82,694
-45.3%
0.04
USD 3,308
|
82,694
-45.3%
|
0.04
|
USD 3,308
|
|
|
2013-07-10 |
2012-11-21 |
S
Sale
|
BERMAN RICHARD J
Non-Executive Director
|
127,632
-41.1%
0.04
USD 4,480
|
127,632
-41.1%
|
0.04
|
USD 4,480
|
|
|
2013-07-10 |
2012-11-21 |
S
Sale
|
BERMAN RICHARD J
Non-Executive Director
|
67,306
-17.8%
0.04
USD 2,524
|
67,306
-17.8%
|
0.04
|
USD 2,524
|
|
|
2013-07-10 |
2012-11-20 |
S
Sale
|
BERMAN RICHARD J
Non-Executive Director
|
150,000
-28.4%
0.04
USD 5,550
|
150,000
-28.4%
|
0.04
|
USD 5,550
|
|
|
2013-07-10 |
2012-11-20 |
S
Sale
|
BERMAN RICHARD J
Non-Executive Director
|
150,000
-22.1%
0.04
USD 5,400
|
150,000
-22.1%
|
0.04
|
USD 5,400
|
|
|
2010-02-19 |
2010-02-12 |
S
Sale
|
BERMAN RICHARD J
Non-Executive Director
|
760,624
-100.0%
0.16
USD 121,700
|
760,624
-100.0%
|
0.16
|
USD 121,700
|
|
|
2007-10-30 |
2007-10-25 |
B
Purchase
|
COBB FREDRICK D
Vice President Finance
Officer
|
40,695
+82.0%
0.18
USD 7,325
|
40,695
+82.0%
|
0.18
|
USD 7,325
|
|
|
2007-10-30 |
2007-10-25 |
B
Purchase
|
ROTHMAN JOHN F
VP Clinical Development
Officer
|
61,043
+28.4%
0.18
USD 10,988
|
61,043
+28.4%
|
0.18
|
USD 10,988
|
|
|
2007-10-26 |
2007-10-23 |
B
Purchase
|
MOORE THOMAS A
CHAIRMAN / CEO
Executive Director
|
2,666,667
+inf%
0.15
USD 400,000
|
2,666,667
+inf%
|
0.15
|
USD 400,000
|
|
|
2007-03-01 |
2007-02-23 |
B
Purchase
|
COBB FREDRICK D
Vice President Finance
Officer
|
49,641
+inf%
0.16
USD 7,943
|
49,641
+inf%
|
0.16
|
USD 7,943
|
|
|
2007-03-01 |
2007-02-23 |
B
Purchase
|
ROTHMAN JOHN F
VP of Clinical Development
Officer
|
134,732
+168.4%
0.16
USD 21,557
|
134,732
+168.4%
|
0.16
|
USD 21,557
|
|
|
2007-01-10 |
2007-01-03 |
B
Purchase
|
APPEL RONI
Non-Executive Director
Large shareholder
|
1,000,000
+33.6%
0.20
USD 200,000
|
1,000,000
+33.6%
|
0.20
|
USD 200,000
|
|
|
2007-01-10 |
2006-01-25 |
B
Purchase
|
APPEL RONI
Non-Executive Director
Large shareholder
|
238,095
+10.0%
0.19
USD 44,048
|
238,095
+10.0%
|
0.19
|
USD 44,048
|
|
