|
2011-11-08 |
2011-11-04 |
GV
Geplanter Verkauf
|
PATTI JOSEPH M
Chief Scientific Officer
Führungsperson
|
35.000
-100.0%
8,00
280.000 USD
|
35.000
-100.0%
|
8,00
|
280.000 USD
|
|
|
2011-11-02 |
2011-11-01 |
GV
Geplanter Verkauf
|
MEDFORD RUSSELL M
Nicht geschäftsführender Verwaltungsratsmitglied
|
350
-0.9%
4,00
1.400 USD
|
350
-0.9%
|
4,00
|
1.400 USD
|
|
|
2011-09-28 |
2011-09-27 |
V
Verkauf
|
QVT Associates GP LLC
Large shareholder
|
200.000
-2.5%
3,00
600.000 USD
|
200.000
-2.5%
|
3,00
|
600.000 USD
|
|
|
2011-09-28 |
2011-09-26 |
V
Verkauf
|
QVT Associates GP LLC
Large shareholder
|
2.500
-0.0%
3,01
7.525 USD
|
2.500
-0.0%
|
3,01
|
7.525 USD
|
|
|
2011-09-28 |
2011-09-26 |
V
Verkauf
|
QVT Associates GP LLC
Large shareholder
|
1.400
-0.0%
3,10
4.340 USD
|
1.400
-0.0%
|
3,10
|
4.340 USD
|
|
|
2011-09-28 |
2011-09-26 |
V
Verkauf
|
QVT Associates GP LLC
Large shareholder
|
30.000
-0.4%
2,97
89.100 USD
|
30.000
-0.4%
|
2,97
|
89.100 USD
|
|
|
2011-06-02 |
2011-05-31 |
V
Verkauf
|
QVT Associates GP LLC
Large shareholder
|
55.000
-0.7%
4,58
251.900 USD
|
55.000
-0.7%
|
4,58
|
251.900 USD
|
|
|
2011-06-02 |
2011-05-31 |
V
Verkauf
|
QVT Associates GP LLC
Large shareholder
|
600.000
-7.0%
4,49
2.694.000 USD
|
600.000
-7.0%
|
4,49
|
2.694.000 USD
|
|
|
2011-04-11 |
2011-04-11 |
V
Verkauf
|
QVT Associates GP LLC
Large shareholder
|
78.335
-0.9%
4,29
336.057 USD
|
78.335
-0.9%
|
4,29
|
336.057 USD
|
|
|
2011-04-11 |
2011-04-11 |
V
Verkauf
|
QVT Associates GP LLC
Large shareholder
|
60.717
-0.7%
4,28
259.869 USD
|
60.717
-0.7%
|
4,28
|
259.869 USD
|
|
|
2011-04-11 |
2011-04-08 |
V
Verkauf
|
QVT Associates GP LLC
Large shareholder
|
105.382
-1.2%
4,39
462.627 USD
|
105.382
-1.2%
|
4,39
|
462.627 USD
|
|
|
2011-04-11 |
2011-04-08 |
V
Verkauf
|
QVT Associates GP LLC
Large shareholder
|
230.000
-2.5%
4,37
1.005.100 USD
|
230.000
-2.5%
|
4,37
|
1.005.100 USD
|
|
|
2011-04-11 |
2011-04-07 |
V
Verkauf
|
QVT Associates GP LLC
Large shareholder
|
129.757
-1.4%
4,52
586.502 USD
|
129.757
-1.4%
|
4,52
|
586.502 USD
|
|
|
2009-12-18 |
2009-12-16 |
K
Kauf
|
QVT Associates GP LLC
Large shareholder
|
43.000
+0.5%
0,85
36.550 USD
|
43.000
+0.5%
|
0,85
|
36.550 USD
|
|
|
2009-12-15 |
2009-12-11 |
K
Kauf
|
QVT Associates GP LLC
Large shareholder
|
25.000
+0.3%
0,72
17.875 USD
|
25.000
+0.3%
|
0,72
|
17.875 USD
|
|
|
2009-12-11 |
2009-12-10 |
K
Kauf
|
QVT Associates GP LLC
Large shareholder
|
75.000
+0.8%
0,73
54.750 USD
|
75.000
+0.8%
|
0,73
|
54.750 USD
|
|
|
2009-12-11 |
2009-12-09 |
K
Kauf
|
QVT Associates GP LLC
Large shareholder
|
23.000
+0.3%
0,89
20.470 USD
|
23.000
+0.3%
|
0,89
|
20.470 USD
|
|
|
2009-12-09 |
2009-12-07 |
K
Kauf
|
QVT Associates GP LLC
Large shareholder
|
27.000
+0.3%
0,92
24.840 USD
|
27.000
+0.3%
|
0,92
|
24.840 USD
|
|
|
2009-12-07 |
2009-12-04 |
K
Kauf
|
QVT Associates GP LLC
Large shareholder
|
21.500
+0.2%
0,96
20.640 USD
|
21.500
+0.2%
|
0,96
|
20.640 USD
|
|
|
2009-12-07 |
2009-12-03 |
K
Kauf
|
QVT Associates GP LLC
Large shareholder
|
25.000
+0.3%
0,99
24.750 USD
|
25.000
+0.3%
|
0,99
|
24.750 USD
|
|
|
2009-12-03 |
2009-12-02 |
K
Kauf
|
QVT Associates GP LLC
Large shareholder
|
14.000
+0.2%
0,98
13.720 USD
|
14.000
+0.2%
|
0,98
|
13.720 USD
|
|
|
2009-12-03 |
2009-12-01 |
K
Kauf
|
QVT Associates GP LLC
Large shareholder
|
51.000
+0.6%
0,98
49.980 USD
|
51.000
+0.6%
|
0,98
|
49.980 USD
|
|
|
2009-12-01 |
2009-11-30 |
K
Kauf
|
QVT Associates GP LLC
Large shareholder
|
50.000
+0.6%
0,99
49.500 USD
|
50.000
+0.6%
|
0,99
|
49.500 USD
|
|
|
2009-12-01 |
2009-11-27 |
K
Kauf
|
QVT Associates GP LLC
Large shareholder
|
12.300
+0.1%
0,96
11.808 USD
|
12.300
+0.1%
|
0,96
|
11.808 USD
|
|
|
2009-12-01 |
2009-11-27 |
K
Kauf
|
QVT Associates GP LLC
Large shareholder
|
2.000
+0.0%
0,96
1.920 USD
|
2.000
+0.0%
|
0,96
|
1.920 USD
|
|
|
2009-11-27 |
2009-11-25 |
K
Kauf
|
QVT Associates GP LLC
Large shareholder
|
300
+0.0%
1,00
300 USD
|
300
+0.0%
|
1,00
|
300 USD
|
|
|
2009-11-27 |
2009-11-24 |
K
Kauf
|
QVT Associates GP LLC
Large shareholder
|
16.292
+0.2%
0,98
15.966 USD
|
16.292
+0.2%
|
0,98
|
15.966 USD
|
|
|
2009-11-24 |
2009-11-23 |
K
Kauf
|
QVT Associates GP LLC
Large shareholder
|
13.000
+0.1%
0,99
12.870 USD
|
13.000
+0.1%
|
0,99
|
12.870 USD
|
|
|
2009-11-24 |
2009-11-20 |
K
Kauf
|
QVT Associates GP LLC
Large shareholder
|
11.700
+0.1%
0,99
11.583 USD
|
11.700
+0.1%
|
0,99
|
11.583 USD
|
|
|
2009-11-24 |
2009-11-19 |
K
Kauf
|
QVT Associates GP LLC
Large shareholder
|
11.000
+0.1%
0,98
10.780 USD
|
11.000
+0.1%
|
0,98
|
10.780 USD
|
|
|
2009-11-19 |
2009-11-18 |
K
Kauf
|
QVT Associates GP LLC
Large shareholder
|
85.000
+1.0%
0,99
84.150 USD
|
85.000
+1.0%
|
0,99
|
84.150 USD
|
|
|
2009-11-19 |
2009-11-17 |
K
Kauf
|
QVT Associates GP LLC
Large shareholder
|
9.500
+0.1%
0,98
9.310 USD
|
9.500
+0.1%
|
0,98
|
9.310 USD
|
|
|
2009-11-13 |
2009-11-12 |
K
Kauf
|
QVT Associates GP LLC
Large shareholder
|
19.000
+0.2%
0,99
18.810 USD
|
19.000
+0.2%
|
0,99
|
18.810 USD
|
|
|
2009-11-13 |
2009-11-11 |
K
Kauf
|
QVT Associates GP LLC
Large shareholder
|
100.000
+1.2%
1,00
100.000 USD
|
100.000
+1.2%
|
1,00
|
100.000 USD
|
|
|
2009-11-12 |
2009-11-10 |
K
Kauf
|
QVT Associates GP LLC
Large shareholder
|
13.000
+0.2%
1,00
13.000 USD
|
13.000
+0.2%
|
1,00
|
13.000 USD
|
|
|
2009-11-12 |
2009-11-09 |
K
Kauf
|
QVT Associates GP LLC
Large shareholder
|
71.000
+0.8%
0,99
70.290 USD
|
71.000
+0.8%
|
0,99
|
70.290 USD
|
|
|
2009-11-09 |
2009-11-06 |
K
Kauf
|
QVT Associates GP LLC
Large shareholder
|
46.000
+0.5%
0,99
45.540 USD
|
46.000
+0.5%
|
0,99
|
45.540 USD
|
|
|
2009-11-09 |
2009-11-05 |
K
Kauf
|
QVT Associates GP LLC
Large shareholder
|
48.000
+0.6%
0,99
47.520 USD
|
48.000
+0.6%
|
0,99
|
47.520 USD
|
|
|
2009-11-05 |
2009-11-04 |
K
Kauf
|
QVT Associates GP LLC
Large shareholder
|
79.000
+1.0%
1,00
79.000 USD
|
79.000
+1.0%
|
1,00
|
79.000 USD
|
|
|
2009-11-05 |
2009-11-03 |
K
Kauf
|
QVT Associates GP LLC
Large shareholder
|
5.000
+0.1%
0,99
4.950 USD
|
5.000
+0.1%
|
0,99
|
4.950 USD
|
|
|
2009-11-05 |
2009-11-03 |
K
Kauf
|
QVT Associates GP LLC
Large shareholder
|
50.000
+0.6%
0,99
49.500 USD
|
50.000
+0.6%
|
0,99
|
49.500 USD
|
|
|
2009-11-03 |
2009-11-02 |
K
Kauf
|
QVT Associates GP LLC
Large shareholder
|
2.600
+0.0%
0,97
2.522 USD
|
2.600
+0.0%
|
0,97
|
2.522 USD
|
|
|
2009-11-03 |
2009-11-02 |
K
Kauf
|
QVT Associates GP LLC
Large shareholder
|
14.880
+0.2%
0,99
14.731 USD
|
14.880
+0.2%
|
0,99
|
14.731 USD
|
|
|
2009-11-03 |
2009-10-30 |
K
Kauf
|
QVT Associates GP LLC
Large shareholder
|
27.556
+0.3%
0,99
27.280 USD
|
27.556
+0.3%
|
0,99
|
27.280 USD
|
|
|
2009-10-30 |
2009-10-28 |
K
Kauf
|
PERRY MARK W
Large shareholder
|
1.757.812
+34.2%
1,28
2.249.999 USD
|
1.757.812
+34.2%
|
1,28
|
2.249.999 USD
|
|
|
2009-10-30 |
2009-10-28 |
K
Kauf
|
BARRETT M JAMES
Nicht geschäftsführender Verwaltungsratsmitglied
Large shareholder
|
1.757.812
+34.2%
1,28
2.249.999 USD
|
1.757.812
+34.2%
|
1,28
|
2.249.999 USD
|
|
|
2009-10-30 |
2009-10-28 |
K
Kauf
|
BARRIS PETER J
Large shareholder
|
1.757.812
+34.2%
1,28
2.249.999 USD
|
1.757.812
+34.2%
|
1,28
|
2.249.999 USD
|
|
|
2009-10-30 |
2009-10-28 |
K
Kauf
|
SANDELL SCOTT D
Large shareholder
|
1.757.812
+34.2%
1,28
2.249.999 USD
|
1.757.812
+34.2%
|
1,28
|
2.249.999 USD
|
|
|
2009-10-30 |
2009-10-28 |
K
Kauf
|
NEWHALL CHARLES W III
Large shareholder
|
1.757.812
+34.2%
1,28
2.249.999 USD
|
1.757.812
+34.2%
|
1,28
|
2.249.999 USD
|
|
|
2009-10-30 |
2009-10-28 |
K
Kauf
|
TRAINOR III EUGENE A
Large shareholder
|
1.757.812
+34.2%
1,28
2.249.999 USD
|
1.757.812
+34.2%
|
1,28
|
2.249.999 USD
|
|
|
2009-10-30 |
2009-10-28 |
K
Kauf
|
KRAMLICH C RICHARD
Large shareholder
|
1.757.812
+34.2%
1,28
2.249.999 USD
|
1.757.812
+34.2%
|
1,28
|
2.249.999 USD
|
|
|
2009-10-30 |
2009-10-28 |
K
Kauf
|
PERRY MARK W
Large shareholder
|
585.937
+43.2%
1,28
749.999 USD
|
585.937
+43.2%
|
1,28
|
749.999 USD
|
|
|
2009-10-30 |
2009-10-28 |
K
Kauf
|
NEW ENTERPRISE ASSOCIATES 10 L P
Large shareholder
|
1.757.812
+34.2%
1,28
2.249.999 USD
|
1.757.812
+34.2%
|
1,28
|
2.249.999 USD
|
|
|
2009-10-30 |
2009-10-28 |
K
Kauf
|
BARRETT M JAMES
Nicht geschäftsführender Verwaltungsratsmitglied
Large shareholder
|
585.937
+43.2%
1,28
749.999 USD
|
585.937
+43.2%
|
1,28
|
749.999 USD
|
|
|
2009-10-30 |
2009-10-28 |
K
Kauf
|
BARRIS PETER J
Large shareholder
|
585.937
+43.2%
1,28
749.999 USD
|
585.937
+43.2%
|
1,28
|
749.999 USD
|
|
|
2009-10-30 |
2009-10-28 |
K
Kauf
|
SANDELL SCOTT D
Large shareholder
|
585.937
+43.2%
1,28
749.999 USD
|
585.937
+43.2%
|
1,28
|
749.999 USD
|
|
|
2009-10-30 |
2009-10-28 |
K
Kauf
|
NEWHALL CHARLES W III
Large shareholder
|
585.937
+43.2%
1,28
749.999 USD
|
585.937
+43.2%
|
1,28
|
749.999 USD
|
|
|
2009-10-30 |
2009-10-28 |
K
Kauf
|
TRAINOR III EUGENE A
Large shareholder
|
585.937
+43.2%
1,28
749.999 USD
|
585.937
+43.2%
|
1,28
|
749.999 USD
|
|
|
2009-10-30 |
2009-10-28 |
K
Kauf
|
KRAMLICH C RICHARD
Large shareholder
|
585.937
+43.2%
1,28
749.999 USD
|
585.937
+43.2%
|
1,28
|
749.999 USD
|
|
|
2008-12-04 |
2008-12-03 |
K
Kauf
|
Henson Geoffrey W.
Vice President
Führungsperson
|
140.000
+954.6%
0,25
35.000 USD
|
140.000
+954.6%
|
0,25
|
35.000 USD
|
|
|
2008-12-03 |
2008-12-02 |
K
Kauf
|
PLUMB RUSSELL H
CEO, Chief Executive Officer
Geschäftsführender Verwaltungsratsmitglied
|
7.400
+3.5%
0,24
1.805 USD
|
7.400
+3.5%
|
0,24
|
1.805 USD
|
|
|
2008-12-01 |
2008-11-25 |
K
Kauf
|
PLUMB RUSSELL H
CEO, Chief Executive Officer
Geschäftsführender Verwaltungsratsmitglied
|
5.600
+2.7%
0,25
1.387 USD
|
5.600
+2.7%
|
0,25
|
1.387 USD
|
|
|
2008-11-21 |
2008-11-20 |
K
Kauf
|
PLUMB RUSSELL H
CEO, Chief Executive Officer
Geschäftsführender Verwaltungsratsmitglied
|
16.600
+8.8%
0,21
3.536 USD
|
16.600
+8.8%
|
0,21
|
3.536 USD
|
|
|
2008-11-17 |
2008-11-14 |
K
Kauf
|
PATTI JOSEPH M
Chief Scientific Officer
Führungsperson
|
20.000
+16.8%
0,22
4.400 USD
|
20.000
+16.8%
|
0,22
|
4.400 USD
|
|
|
2006-05-11 |
2006-05-11 |
K
Kauf
|
Willard A Keith
Nicht geschäftsführender Verwaltungsratsmitglied
|
2.500
+inf%
1,99
4.975 USD
|
2.500
+inf%
|
1,99
|
4.975 USD
|
|
|
2006-01-18 |
2006-01-13 |
GV
Geplanter Verkauf
|
PATTI JOSEPH M
Chief Scientific Officer
Geschäftsführender Verwaltungsratsmitglied
|
35.000
-50.3%
9,04
316.425 USD
|
35.000
-50.3%
|
9,04
|
316.425 USD
|
|
|
2006-01-13 |
2006-01-12 |
GV
Geplanter Verkauf
|
PATTI JOSEPH M
Chief Scientific Officer
Geschäftsführender Verwaltungsratsmitglied
|
30.000
-30.1%
9,05
271.401 USD
|
30.000
-30.1%
|
9,05
|
271.401 USD
|
|
|
2006-01-13 |
2006-01-11 |
GV
Geplanter Verkauf
|
PATTI JOSEPH M
Chief Scientific Officer
Geschäftsführender Verwaltungsratsmitglied
|
12.350
-11.0%
9,01
111.271 USD
|
12.350
-11.0%
|
9,01
|
111.271 USD
|
|
|
2006-01-11 |
2006-01-10 |
GV
Geplanter Verkauf
|
PATTI JOSEPH M
Chief Scientific Officer
Geschäftsführender Verwaltungsratsmitglied
|
27.650
-19.8%
9,00
248.850 USD
|
27.650
-19.8%
|
9,00
|
248.850 USD
|
|
|
2006-01-11 |
2006-01-10 |
GV
Geplanter Verkauf
|
HETHERINGTON SETH V
VP, Clinical Development & CMO
Führungsperson
|
8.305
-100.0%
9,00
74.745 USD
|
8.305
-100.0%
|
9,00
|
74.745 USD
|
|
|
2006-01-11 |
2006-01-10 |
GV
Geplanter Verkauf
|
PLUMB RUSSELL H
CFO, VP of Admin. & Finance
Führungsperson
|
20.000
-50.8%
9,00
180.000 USD
|
20.000
-50.8%
|
9,00
|
180.000 USD
|
|
|
2006-01-06 |
2006-01-05 |
GV
Geplanter Verkauf
|
JOHNSTON WILLIAM D
President & CEO
Geschäftsführender Verwaltungsratsmitglied
|
2.200
-3.2%
8,47
18.633 USD
|
2.200
-3.2%
|
8,47
|
18.633 USD
|
|
|
2006-01-05 |
2006-01-04 |
GV
Geplanter Verkauf
|
JOHNSTON WILLIAM D
President & CEO
Geschäftsführender Verwaltungsratsmitglied
|
15.900
-18.8%
8,46
134.508 USD
|
15.900
-18.8%
|
8,46
|
134.508 USD
|
|
|
2006-01-04 |
2006-01-03 |
GV
Geplanter Verkauf
|
JOHNSTON WILLIAM D
President & CEO
Geschäftsführender Verwaltungsratsmitglied
|
16.200
-1.9%
8,41
136.227 USD
|
16.200
-1.9%
|
8,41
|
136.227 USD
|
|
|
2004-11-12 |
2004-11-10 |
K
Kauf
|
ALSOP STEWART II
Large shareholder
|
1.937.970
+42.5%
7,34
14.224.700 USD
|
1.937.970
+42.5%
|
7,34
|
14.224.700 USD
|
|
