|
2023-01-31 |
2023-01-27 |
V
Verkauf
|
PAKIANATHAN DEEPIKA
Nicht geschäftsführender Verwaltungsratsmitglied
|
1.172
-100.0%
0,39
452 USD
|
1.172
-100.0%
|
0,39
|
452 USD
|
|
|
2023-01-31 |
2023-01-27 |
V
Verkauf
|
PAKIANATHAN DEEPIKA
Nicht geschäftsführender Verwaltungsratsmitglied
|
120.161
-100.0%
0,39
46.358 USD
|
120.161
-100.0%
|
0,39
|
46.358 USD
|
|
|
2021-11-12 |
2021-11-11 |
V
Verkauf
|
Orford Keith
Director
Führungsperson
|
48.190
-42.2%
0,88
42.407 USD
|
48.190
-42.2%
|
0,88
|
42.407 USD
|
|
|
2021-11-12 |
2021-11-10 |
V
Verkauf
|
Orford Keith
Director
Führungsperson
|
30.000
-20.8%
0,86
25.695 USD
|
30.000
-20.8%
|
0,86
|
25.695 USD
|
|
|
2021-11-10 |
2021-11-10 |
K
Kauf
|
DRACHMAN JONATHAN G
Nicht geschäftsführender Verwaltungsratsmitglied
|
200.000
+inf%
0,86
171.900 USD
|
200.000
+inf%
|
0,86
|
171.900 USD
|
|
|
2021-11-10 |
2021-11-10 |
K
Kauf
|
Molineaux Christopher
SR. VP, DEVELOPMENT
Führungsperson
|
100.000
+21.9%
0,85
84.670 USD
|
100.000
+21.9%
|
0,85
|
84.670 USD
|
|
|
2021-11-10 |
2021-11-10 |
K
Kauf
|
Molineaux Susan
PRESIDENT & CEO
Geschäftsführender Verwaltungsratsmitglied
|
100.000
+21.9%
0,85
84.670 USD
|
100.000
+21.9%
|
0,85
|
84.670 USD
|
|
|
2021-11-09 |
2021-11-09 |
V
Verkauf
|
Orford Keith
Nicht geschäftsführender Verwaltungsratsmitglied
|
51.810
-26.4%
0,84
43.520 USD
|
51.810
-26.4%
|
0,84
|
43.520 USD
|
|
|
2020-12-18 |
2020-12-16 |
GV
Geplanter Verkauf
|
Orford Keith
Chief Medical Officer
Führungsperson
|
2.447
-18.1%
6,00
14.682 USD
|
2.447
-18.1%
|
6,00
|
14.682 USD
|
|
|
2020-05-26 |
2020-05-21 |
V
Verkauf
|
BVF PARTNERS L P/IL
Large shareholder
|
192.250
-28.6%
6,00
1.153.500 USD
|
192.250
-28.6%
|
6,00
|
1.153.500 USD
|
|
|
2020-05-26 |
2020-05-21 |
V
Verkauf
|
BVF PARTNERS L P/IL
Large shareholder
|
1.064.332
-27.8%
6,00
6.385.992 USD
|
1.064.332
-27.8%
|
6,00
|
6.385.992 USD
|
|
|
2020-05-26 |
2020-05-21 |
V
Verkauf
|
BVF PARTNERS L P/IL
Large shareholder
|
1.027.016
-21.7%
6,00
6.162.096 USD
|
1.027.016
-21.7%
|
6,00
|
6.162.096 USD
|
|
|
2020-04-17 |
2020-04-15 |
GV
Geplanter Verkauf
|
Wong Stephanie
SR. VP, FINANCE & SECRETARY
Führungsperson
|
5.000
-14.3%
8,00
40.000 USD
|
5.000
-14.3%
|
8,00
|
40.000 USD
|
|
|
2020-02-24 |
2020-02-20 |
GV
Geplanter Verkauf
|
Orford Keith
Chief Medical Officer
Führungsperson
|
3.021
-26.1%
8,00
24.168 USD
|
3.021
-26.1%
|
8,00
|
24.168 USD
|
|
|
2019-12-26 |
2019-12-23 |
GV
Geplanter Verkauf
|
Orford Keith
Chief Medical Officer
Führungsperson
|
3.021
-20.7%
6,00
18.126 USD
|
3.021
-20.7%
|
6,00
|
18.126 USD
|
|
|
2019-11-22 |
2019-11-20 |
K
Kauf
|
BVF PARTNERS L P/IL
Large shareholder
|
14.151
+2.1%
3,91
55.353 USD
|
14.151
+2.1%
|
3,91
|
55.353 USD
|
|
|
2019-11-22 |
2019-11-20 |
K
Kauf
|
BVF PARTNERS L P/IL
Large shareholder
|
79.285
+2.1%
3,91
310.131 USD
|
79.285
+2.1%
|
3,91
|
310.131 USD
|
|
|
2019-11-22 |
2019-11-20 |
K
Kauf
|
BVF PARTNERS L P/IL
Large shareholder
|
98.518
+2.1%
3,91
385.363 USD
|
98.518
+2.1%
|
3,91
|
385.363 USD
|
|
|
2019-11-18 |
2019-11-14 |
K
Kauf
|
BVF PARTNERS L P/IL
Large shareholder
|
11.105
+1.7%
3,37
37.424 USD
|
11.105
+1.7%
|
3,37
|
37.424 USD
|
|
|
2019-11-18 |
2019-11-14 |
K
Kauf
|
BVF PARTNERS L P/IL
Large shareholder
|
45.888
+1.2%
3,37
154.643 USD
|
45.888
+1.2%
|
3,37
|
154.643 USD
|
|
|
2019-11-18 |
2019-11-14 |
K
Kauf
|
BVF PARTNERS L P/IL
Large shareholder
|
71.495
+1.6%
3,37
240.938 USD
|
71.495
+1.6%
|
3,37
|
240.938 USD
|
|
|
2019-10-31 |
2019-10-30 |
K
Kauf
|
BVF PARTNERS L P/IL
Large shareholder
|
57.868
+9.8%
2,70
156.244 USD
|
57.868
+9.8%
|
2,70
|
156.244 USD
|
|
|
2019-10-31 |
2019-10-30 |
K
Kauf
|
BVF PARTNERS L P/IL
Large shareholder
|
331.048
+9.8%
2,70
893.830 USD
|
331.048
+9.8%
|
2,70
|
893.830 USD
|
|
|
2019-10-31 |
2019-10-30 |
K
Kauf
|
BVF PARTNERS L P/IL
Large shareholder
|
408.592
+9.8%
2,70
1.103.198 USD
|
408.592
+9.8%
|
2,70
|
1.103.198 USD
|
|
|
2019-10-31 |
2019-10-29 |
K
Kauf
|
BVF PARTNERS L P/IL
Large shareholder
|
116.552
+24.6%
2,60
303.035 USD
|
116.552
+24.6%
|
2,60
|
303.035 USD
|
|
|
2019-10-31 |
2019-10-29 |
K
Kauf
|
BVF PARTNERS L P/IL
Large shareholder
|
610.052
+22.1%
2,60
1.586.135 USD
|
610.052
+22.1%
|
2,60
|
1.586.135 USD
|
|
|
2019-10-31 |
2019-10-29 |
K
Kauf
|
BVF PARTNERS L P/IL
Large shareholder
|
872.373
+26.5%
2,60
2.268.170 USD
|
872.373
+26.5%
|
2,60
|
2.268.170 USD
|
|
|
2019-06-27 |
2019-06-25 |
GK
Geplanter Kauf
|
Molineaux Christopher
SR. VP, DEVELOPMENT
|
51.600
+12.7%
3,88
200.208 USD
|
51.600
+12.7%
|
3,88
|
200.208 USD
|
|
|
2019-06-27 |
2019-06-25 |
GK
Geplanter Kauf
|
Molineaux Susan
PRESIDENT AND CEO
Geschäftsführender Verwaltungsratsmitglied
|
51.600
+12.7%
3,88
200.208 USD
|
51.600
+12.7%
|
3,88
|
200.208 USD
|
|
|
2019-06-19 |
2019-06-17 |
GV
Geplanter Verkauf
|
Orford Keith
Chief Medical Officer
|
417
-3.3%
6,00
2.502 USD
|
417
-3.3%
|
6,00
|
2.502 USD
|
|
|
2019-05-24 |
2019-05-22 |
GV
Geplanter Verkauf
|
Orford Keith
Chief Medical Officer
|
416
-4.0%
6,00
2.496 USD
|
416
-4.0%
|
6,00
|
2.496 USD
|
|
|
2019-04-17 |
2019-04-15 |
GV
Geplanter Verkauf
|
Orford Keith
Chief Medical Officer
|
416
-3.8%
6,33
2.633 USD
|
416
-3.8%
|
6,33
|
2.633 USD
|
|
|
2019-03-19 |
2019-03-15 |
GV
Geplanter Verkauf
|
Orford Keith
Chief Medical Officer
|
417
-3.7%
6,43
2.681 USD
|
417
-3.7%
|
6,43
|
2.681 USD
|
|
|
2019-03-13 |
2019-03-11 |
GV
Geplanter Verkauf
|
Orford Keith
Chief Medical Officer
Führungsperson
|
1.565
-12.2%
6,00
9.390 USD
|
1.565
-12.2%
|
6,00
|
9.390 USD
|
|
|
2018-10-17 |
2018-10-15 |
GV
Geplanter Verkauf
|
Orford Keith
SR. VP, CLINICAL DEVELOPMENT
Führungsperson
|
313
-2.9%
6,05
1.894 USD
|
313
-2.9%
|
6,05
|
1.894 USD
|
|
|
2018-10-15 |
2018-10-11 |
GV
Geplanter Verkauf
|
Orford Keith
SR. VP, CLINICAL DEVELOPMENT
Führungsperson
|
1.252
-10.5%
6,00
7.512 USD
|
1.252
-10.5%
|
6,00
|
7.512 USD
|
|
|
2017-09-28 |
2017-09-28 |
V
Verkauf
|
ADAGE CAPITAL PARTNERS GP, L.L.C.
Large shareholder
|
38.000
-1.1%
15,50
589.000 USD
|
38.000
-1.1%
|
15,50
|
589.000 USD
|
|
|
2017-09-28 |
2017-09-27 |
V
Verkauf
|
ADAGE CAPITAL PARTNERS GP, L.L.C.
Large shareholder
|
186.000
-4.9%
15,59
2.899.740 USD
|
186.000
-4.9%
|
15,59
|
2.899.740 USD
|
|
|
2017-09-28 |
2017-09-26 |
V
Verkauf
|
ADAGE CAPITAL PARTNERS GP, L.L.C.
Large shareholder
|
352.000
-8.5%
15,68
5.519.360 USD
|
352.000
-8.5%
|
15,68
|
5.519.360 USD
|
|
|
2017-07-19 |
2017-07-17 |
GV
Geplanter Verkauf
|
Wong Stephanie
VP, FINANCE AND SECRETARY
Führungsperson
|
3.552
-25.2%
18,41
65.385 USD
|
3.552
-25.2%
|
18,41
|
65.385 USD
|
|
|
2017-07-19 |
2017-07-17 |
GV
Geplanter Verkauf
|
Orford Keith
SR. VP, CLINICAL DEVELOPMENT
Führungsperson
|
2.120
-23.6%
18,31
38.823 USD
|
2.120
-23.6%
|
18,31
|
38.823 USD
|
|
|
2017-07-07 |
2017-07-06 |
GV
Geplanter Verkauf
|
Hecht Curtis
SVP, BUS. & CORP. DEVELOPMENT
Führungsperson
|
700
-4.2%
18,00
12.600 USD
|
700
-4.2%
|
18,00
|
12.600 USD
|
|
|
2017-05-23 |
2017-05-19 |
GV
Geplanter Verkauf
|
Hecht Curtis
SVP, BUS. & CORP. DEVELOPMENT
Führungsperson
|
650
-4.2%
16,00
10.400 USD
|
650
-4.2%
|
16,00
|
10.400 USD
|
|
|
2017-03-24 |
2017-03-22 |
K
Kauf
|
ADAGE CAPITAL PARTNERS GP, L.L.C.
Large shareholder
|
487.804
+13.4%
10,25
4.999.991 USD
|
487.804
+13.4%
|
10,25
|
4.999.991 USD
|
|
|
2017-03-15 |
2017-03-13 |
GV
Geplanter Verkauf
|
Hecht Curtis
SVP, BUS. & CORP. DEVELOPMENT
|
600
-3.7%
14,00
8.400 USD
|
600
-3.7%
|
14,00
|
8.400 USD
|
|
|
2017-03-06 |
2017-03-02 |
GV
Geplanter Verkauf
|
Hecht Curtis
See Remarks
|
550
-3.3%
12,00
6.600 USD
|
550
-3.3%
|
12,00
|
6.600 USD
|
|
|
2016-11-17 |
2016-11-16 |
K
Kauf
|
ADAGE CAPITAL PARTNERS GP, L.L.C.
Large shareholder
|
500.000
+15.9%
3,15
1.575.000 USD
|
500.000
+15.9%
|
3,15
|
1.575.000 USD
|
|
|
2015-09-24 |
2015-09-23 |
K
Kauf
|
ADAGE CAPITAL PARTNERS GP LLC
Large shareholder
|
40.168
+1.3%
6,07
243.768 USD
|
40.168
+1.3%
|
6,07
|
243.768 USD
|
|
|
2015-09-24 |
2015-09-22 |
K
Kauf
|
ADAGE CAPITAL PARTNERS GP LLC
Large shareholder
|
41.800
+1.4%
6,00
250.938 USD
|
41.800
+1.4%
|
6,00
|
250.938 USD
|
|
|
2015-09-24 |
2015-09-22 |
K
Kauf
|
ADAGE CAPITAL PARTNERS GP LLC
Large shareholder
|
25.000
+0.8%
6,00
149.943 USD
|
25.000
+0.8%
|
6,00
|
149.943 USD
|
|
|
2015-09-08 |
2015-09-04 |
K
Kauf
|
ADAGE CAPITAL PARTNERS GP LLC
Large shareholder
|
2.300
+0.1%
5,95
13.685 USD
|
2.300
+0.1%
|
5,95
|
13.685 USD
|
|
|
2015-09-08 |
2015-09-03 |
K
Kauf
|
ADAGE CAPITAL PARTNERS GP LLC
Large shareholder
|
88.000
+3.0%
5,93
521.840 USD
|
88.000
+3.0%
|
5,93
|
521.840 USD
|
|
|
2015-08-28 |
2015-08-28 |
K
Kauf
|
ADAGE CAPITAL PARTNERS GP LLC
Large shareholder
|
22.000
+0.8%
5,58
122.760 USD
|
22.000
+0.8%
|
5,58
|
122.760 USD
|
|
|
2015-08-28 |
2015-08-28 |
K
Kauf
|
ADAGE CAPITAL PARTNERS GP LLC
Large shareholder
|
20.700
+0.7%
5,55
114.885 USD
|
20.700
+0.7%
|
5,55
|
114.885 USD
|
|
|
2015-08-28 |
2015-08-27 |
K
Kauf
|
ADAGE CAPITAL PARTNERS GP LLC
Large shareholder
|
32.400
+1.1%
5,35
173.340 USD
|
32.400
+1.1%
|
5,35
|
173.340 USD
|
|
|
2015-08-28 |
2015-08-27 |
K
Kauf
|
ADAGE CAPITAL PARTNERS GP LLC
Large shareholder
|
29.089
+1.0%
5,17
150.390 USD
|
29.089
+1.0%
|
5,17
|
150.390 USD
|
|
|
2015-08-28 |
2015-08-27 |
K
Kauf
|
ADAGE CAPITAL PARTNERS GP LLC
Large shareholder
|
19.578
+0.7%
5,58
109.245 USD
|
19.578
+0.7%
|
5,58
|
109.245 USD
|
|
|
2015-08-28 |
2015-08-27 |
K
Kauf
|
ADAGE CAPITAL PARTNERS GP LLC
Large shareholder
|
6.253
+0.2%
5,43
33.954 USD
|
6.253
+0.2%
|
5,43
|
33.954 USD
|
|
|
2015-08-28 |
2015-08-27 |
K
Kauf
|
ADAGE CAPITAL PARTNERS GP LLC
Large shareholder
|
9.848
+0.4%
5,41
53.278 USD
|
9.848
+0.4%
|
5,41
|
53.278 USD
|
|
|
2015-08-28 |
2015-08-26 |
K
Kauf
|
ADAGE CAPITAL PARTNERS GP LLC
Large shareholder
|
32.058
+1.2%
4,65
149.070 USD
|
32.058
+1.2%
|
4,65
|
149.070 USD
|
|
|
2015-08-28 |
2015-08-26 |
K
Kauf
|
ADAGE CAPITAL PARTNERS GP LLC
Large shareholder
|
200
+0.0%
4,70
940 USD
|
200
+0.0%
|
4,70
|
940 USD
|
|
|
2014-10-15 |
2014-10-15 |
K
Kauf
|
ADAGE CAPITAL PARTNERS GP LLC
Large shareholder
|
25.000
+0.9%
6,80
170.000 USD
|
25.000
+0.9%
|
6,80
|
170.000 USD
|
|
|
2014-10-15 |
2014-10-15 |
K
Kauf
|
ADAGE CAPITAL PARTNERS GP LLC
Large shareholder
|
13.000
+0.5%
7,25
94.250 USD
|
13.000
+0.5%
|
7,25
|
94.250 USD
|
|
|
2014-10-15 |
2014-10-14 |
K
Kauf
|
ADAGE CAPITAL PARTNERS GP LLC
Large shareholder
|
25.000
+0.9%
6,99
174.750 USD
|
25.000
+0.9%
|
6,99
|
174.750 USD
|
|
|
2014-10-15 |
2014-10-14 |
K
Kauf
|
ADAGE CAPITAL PARTNERS GP LLC
Large shareholder
|
30.000
+1.1%
7,00
210.000 USD
|
30.000
+1.1%
|
7,00
|
210.000 USD
|
|
|
2014-10-15 |
2014-10-13 |
K
Kauf
|
ADAGE CAPITAL PARTNERS GP LLC
Large shareholder
|
88.700
+3.4%
6,94
615.578 USD
|
88.700
+3.4%
|
6,94
|
615.578 USD
|
|
|
2014-10-09 |
2014-10-07 |
K
Kauf
|
Delphi Management Partners VIII, L.L.C.
Large shareholder
|
4.835
+26.0%
10,00
48.350 USD
|
4.835
+26.0%
|
10,00
|
48.350 USD
|
|
|
2014-10-09 |
2014-10-07 |
K
Kauf
|
Delphi Management Partners VIII, L.L.C.
Large shareholder
|
495.165
+26.0%
10,00
4.951.650 USD
|
495.165
+26.0%
|
10,00
|
4.951.650 USD
|
|
|
2014-10-09 |
2014-10-07 |
K
Kauf
|
George Jean
Nicht geschäftsführender Verwaltungsratsmitglied
Large shareholder
|
300.000
+16.6%
10,00
3.000.000 USD
|
300.000
+16.6%
|
10,00
|
3.000.000 USD
|
|
|
2014-10-09 |
2014-10-07 |
K
Kauf
|
MORGENTHALER VENTURE PARTNERS IX LP
Large shareholder
|
350.000
+19.3%
10,00
3.500.000 USD
|
350.000
+19.3%
|
10,00
|
3.500.000 USD
|
|
|
2014-10-09 |
2014-10-07 |
K
Kauf
|
Christoffersen Ralph E
Nicht geschäftsführender Verwaltungsratsmitglied
Large shareholder
|
350.000
+19.3%
10,00
3.500.000 USD
|
350.000
+19.3%
|
10,00
|
3.500.000 USD
|
|
|
2014-10-09 |
2014-10-07 |
K
Kauf
|
Advanced Technology Ventures VIII LP
Large shareholder
|
300.000
+16.6%
10,00
3.000.000 USD
|
300.000
+16.6%
|
10,00
|
3.000.000 USD
|
|
|
2014-10-09 |
2014-10-07 |
K
Kauf
|
PAKIANATHAN DEEPIKA
Nicht geschäftsführender Verwaltungsratsmitglied
Large shareholder
|
4.835
+26.0%
10,00
48.350 USD
|
4.835
+26.0%
|
10,00
|
48.350 USD
|
|
|
2014-10-09 |
2014-10-07 |
K
Kauf
|
PAKIANATHAN DEEPIKA
Nicht geschäftsführender Verwaltungsratsmitglied
Large shareholder
|
495.165
+26.0%
10,00
4.951.650 USD
|
495.165
+26.0%
|
10,00
|
4.951.650 USD
|
|
|
2014-10-03 |
2014-10-01 |
K
Kauf
|
ADAGE CAPITAL PARTNERS GP LLC
Large shareholder
|
800.000
+44.9%
10,00
8.000.000 USD
|
800.000
+44.9%
|
10,00
|
8.000.000 USD
|
|
