|
2015-03-17 |
2015-03-16 |
GV
Geplanter Verkauf
|
Stamler David A
Chief Medical Officer
Führungsperson
|
2.600
-72.6%
80,08
208.195 USD
|
2.600
-72.6%
|
80,08
|
208.195 USD
|
|
|
2015-03-17 |
2015-03-16 |
GV
Geplanter Verkauf
|
Stamler David A
Chief Medical Officer
Führungsperson
|
400
-10.0%
79,55
31.820 USD
|
400
-10.0%
|
79,55
|
31.820 USD
|
|
|
2015-02-17 |
2015-02-13 |
V
Verkauf
|
CMEA Ventures VII LP
Large shareholder
|
1.047
-1.4%
62,98
65.943 USD
|
1.047
-1.4%
|
62,98
|
65.943 USD
|
|
|
2015-02-17 |
2015-02-13 |
V
Verkauf
|
CMEA Ventures VII LP
Large shareholder
|
40.786
-1.4%
62,98
2.568.825 USD
|
40.786
-1.4%
|
62,98
|
2.568.825 USD
|
|
|
2015-02-17 |
2015-02-12 |
V
Verkauf
|
CMEA Ventures VII LP
Large shareholder
|
325
-0.4%
64,00
20.800 USD
|
325
-0.4%
|
64,00
|
20.800 USD
|
|
|
2015-02-17 |
2015-02-12 |
V
Verkauf
|
CMEA Ventures VII LP
Large shareholder
|
1.696
-2.1%
62,96
106.782 USD
|
1.696
-2.1%
|
62,96
|
106.782 USD
|
|
|
2015-02-17 |
2015-02-12 |
V
Verkauf
|
CMEA Ventures VII LP
Large shareholder
|
12.675
-0.4%
64,00
811.200 USD
|
12.675
-0.4%
|
64,00
|
811.200 USD
|
|
|
2015-02-17 |
2015-02-12 |
V
Verkauf
|
CMEA Ventures VII LP
Large shareholder
|
66.138
-2.1%
62,96
4.164.128 USD
|
66.138
-2.1%
|
62,96
|
4.164.128 USD
|
|
|
2015-02-11 |
2015-02-11 |
V
Verkauf
|
CMEA Ventures VII LP
Large shareholder
|
1.327
-1.6%
61,84
82.062 USD
|
1.327
-1.6%
|
61,84
|
82.062 USD
|
|
|
2015-02-11 |
2015-02-11 |
V
Verkauf
|
CMEA Ventures VII LP
Large shareholder
|
51.773
-1.6%
61,84
3.201.642 USD
|
51.773
-1.6%
|
61,84
|
3.201.642 USD
|
|
|
2015-02-11 |
2015-02-10 |
V
Verkauf
|
CMEA Ventures VII LP
Large shareholder
|
530
-0.7%
60,05
31.827 USD
|
530
-0.7%
|
60,05
|
31.827 USD
|
|
|
2015-02-11 |
2015-02-10 |
V
Verkauf
|
CMEA Ventures VII LP
Large shareholder
|
20.670
-0.6%
60,05
1.241.234 USD
|
20.670
-0.6%
|
60,05
|
1.241.234 USD
|
|
|
2015-02-11 |
2015-02-09 |
V
Verkauf
|
CMEA Ventures VII LP
Large shareholder
|
246
-0.3%
59,00
14.514 USD
|
246
-0.3%
|
59,00
|
14.514 USD
|
|
|
2015-02-11 |
2015-02-09 |
V
Verkauf
|
CMEA Ventures VII LP
Large shareholder
|
9.608
-0.3%
59,00
566.872 USD
|
9.608
-0.3%
|
59,00
|
566.872 USD
|
|
|
2015-02-06 |
2015-02-06 |
V
Verkauf
|
CMEA Ventures VII LP
Large shareholder
|
757
-0.9%
59,48
45.026 USD
|
757
-0.9%
|
59,48
|
45.026 USD
|
|
|
2015-02-06 |
2015-02-06 |
V
Verkauf
|
CMEA Ventures VII LP
Large shareholder
|
29.522
-0.9%
59,48
1.755.969 USD
|
29.522
-0.9%
|
59,48
|
1.755.969 USD
|
|
|
2015-02-06 |
2015-02-05 |
V
Verkauf
|
CMEA Ventures VII LP
Large shareholder
|
322
-0.4%
59,51
19.162 USD
|
322
-0.4%
|
59,51
|
19.162 USD
|
|
|
2015-02-06 |
2015-02-05 |
V
Verkauf
|
CMEA Ventures VII LP
Large shareholder
|
12.578
-0.4%
59,51
748.517 USD
|
12.578
-0.4%
|
59,51
|
748.517 USD
|
|
|
2015-02-06 |
2015-02-04 |
V
Verkauf
|
CMEA Ventures VII LP
Large shareholder
|
1.250
-1.5%
59,30
74.125 USD
|
1.250
-1.5%
|
59,30
|
74.125 USD
|
|
|
2015-02-06 |
2015-02-04 |
V
Verkauf
|
CMEA Ventures VII LP
Large shareholder
|
48.750
-1.5%
59,30
2.890.875 USD
|
48.750
-1.5%
|
59,30
|
2.890.875 USD
|
|
|
2015-01-30 |
2015-01-28 |
V
Verkauf
|
Thomas, McNerney & Partners II, LLC
Nicht geschäftsführender Verwaltungsratsmitglied
Large shareholder
|
730.000
-13.1%
53,11
38.770.300 USD
|
730.000
-13.1%
|
53,11
|
38.770.300 USD
|
|
|
2015-01-30 |
2015-01-28 |
V
Verkauf
|
Zisson Alex
Nicht geschäftsführender Verwaltungsratsmitglied
|
730.000
-13.1%
53,11
38.770.300 USD
|
730.000
-13.1%
|
53,11
|
38.770.300 USD
|
|
|
2015-01-28 |
2015-01-28 |
K
Kauf
|
Flynn James E
Large shareholder
|
192.240
+24.6%
56,50
10.861.560 USD
|
192.240
+24.6%
|
56,50
|
10.861.560 USD
|
|
|
2015-01-28 |
2015-01-28 |
K
Kauf
|
Flynn James E
Large shareholder
|
167.760
+24.6%
56,50
9.478.440 USD
|
167.760
+24.6%
|
56,50
|
9.478.440 USD
|
|
|
2015-01-28 |
2015-01-28 |
K
Kauf
|
Flynn James E
Large shareholder
|
566.825
+92.0%
56,50
32.025.613 USD
|
566.825
+92.0%
|
56,50
|
32.025.613 USD
|
|
|
2015-01-28 |
2015-01-28 |
K
Kauf
|
Flynn James E
Large shareholder
|
458.175
+92.5%
56,50
25.886.888 USD
|
458.175
+92.5%
|
56,50
|
25.886.888 USD
|
|
|
2015-01-28 |
2015-01-28 |
V
Verkauf
|
FERGUSON RODNEY A
Nicht geschäftsführender Verwaltungsratsmitglied
Large shareholder
|
270.000
-9.7%
53,11
14.339.700 USD
|
270.000
-9.7%
|
53,11
|
14.339.700 USD
|
|
|
2015-01-28 |
2015-01-28 |
V
Verkauf
|
Panorama Capital, L.P.
Large shareholder
|
270.000
-9.7%
53,11
14.339.700 USD
|
270.000
-9.7%
|
53,11
|
14.339.700 USD
|
|
|
2015-01-28 |
2015-01-28 |
K
Kauf
|
Flynn James E
Large shareholder
|
115.000
+30.7%
56,50
6.497.500 USD
|
115.000
+30.7%
|
56,50
|
6.497.500 USD
|
|
|
2015-02-17 |
2015-01-08 |
V
Verkauf
|
CMEA Ventures VII LP
Large shareholder
|
84
-0.1%
49,13
4.127 USD
|
84
-0.1%
|
49,13
|
4.127 USD
|
|
|
2015-02-17 |
2015-01-08 |
V
Verkauf
|
CMEA Ventures VII LP
Large shareholder
|
3.260
-0.1%
49,13
160.161 USD
|
3.260
-0.1%
|
49,13
|
160.161 USD
|
|
|
2014-12-23 |
2014-12-22 |
GV
Geplanter Verkauf
|
Stamler David A
Chief Medical Officer
Führungsperson
|
1.100
-52.8%
53,92
59.316 USD
|
1.100
-52.8%
|
53,92
|
59.316 USD
|
|
|
2014-12-23 |
2014-12-22 |
GV
Geplanter Verkauf
|
Stamler David A
Chief Medical Officer
Führungsperson
|
1.560
-42.8%
53,28
83.118 USD
|
1.560
-42.8%
|
53,28
|
83.118 USD
|
|
|
2014-12-22 |
2014-12-18 |
V
Verkauf
|
CMEA Ventures VII LP
Large shareholder
|
4.875
-5.1%
50,14
244.433 USD
|
4.875
-5.1%
|
50,14
|
244.433 USD
|
|
|
2014-12-22 |
2014-12-18 |
V
Verkauf
|
CMEA Ventures VII LP
Large shareholder
|
190.125
-5.1%
50,14
9.532.868 USD
|
190.125
-5.1%
|
50,14
|
9.532.868 USD
|
|
|
2014-10-31 |
2014-10-30 |
V
Verkauf
|
CMEA Ventures VII LP
Large shareholder
|
197
-0.2%
27,33
5.383 USD
|
197
-0.2%
|
27,33
|
5.383 USD
|
|
|
2014-10-31 |
2014-10-30 |
V
Verkauf
|
CMEA Ventures VII LP
Large shareholder
|
7.633
-0.2%
27,33
208.582 USD
|
7.633
-0.2%
|
27,33
|
208.582 USD
|
|
|
2014-10-31 |
2014-10-29 |
V
Verkauf
|
CMEA Ventures VII LP
Large shareholder
|
279
-0.3%
27,02
7.539 USD
|
279
-0.3%
|
27,02
|
7.539 USD
|
|
|
2014-10-31 |
2014-10-29 |
V
Verkauf
|
CMEA Ventures VII LP
Large shareholder
|
10.891
-0.3%
27,02
294.307 USD
|
10.891
-0.3%
|
27,02
|
294.307 USD
|
|
|
2014-10-29 |
2014-10-28 |
V
Verkauf
|
CMEA Ventures VII LP
Large shareholder
|
275
-0.3%
26,99
7.422 USD
|
275
-0.3%
|
26,99
|
7.422 USD
|
|
|
2014-10-29 |
2014-10-28 |
V
Verkauf
|
CMEA Ventures VII LP
Large shareholder
|
10.725
-0.3%
26,99
289.476 USD
|
10.725
-0.3%
|
26,99
|
289.476 USD
|
|
|
2014-10-29 |
2014-10-27 |
V
Verkauf
|
CMEA Ventures VII LP
Large shareholder
|
87
-0.1%
27,11
2.359 USD
|
87
-0.1%
|
27,11
|
2.359 USD
|
|
|
2014-10-29 |
2014-10-27 |
V
Verkauf
|
CMEA Ventures VII LP
Large shareholder
|
3.413
-0.1%
27,11
92.541 USD
|
3.413
-0.1%
|
27,11
|
92.541 USD
|
|
|
2014-10-27 |
2014-10-24 |
V
Verkauf
|
CMEA Ventures VII LP
Large shareholder
|
272
-0.3%
27,09
7.367 USD
|
272
-0.3%
|
27,09
|
7.367 USD
|
|
|
2014-10-27 |
2014-10-24 |
V
Verkauf
|
CMEA Ventures VII LP
Large shareholder
|
10.628
-0.3%
27,09
287.866 USD
|
10.628
-0.3%
|
27,09
|
287.866 USD
|
|
|
2014-10-27 |
2014-10-23 |
V
Verkauf
|
CMEA Ventures VII LP
Large shareholder
|
140
-0.1%
26,74
3.743 USD
|
140
-0.1%
|
26,74
|
3.743 USD
|
|
|
2014-10-27 |
2014-10-23 |
V
Verkauf
|
CMEA Ventures VII LP
Large shareholder
|
5.460
-0.1%
26,74
145.974 USD
|
5.460
-0.1%
|
26,74
|
145.974 USD
|
|
|
2014-10-08 |
2014-10-06 |
V
Verkauf
|
CMEA Ventures VII LP
Large shareholder
|
178
-0.2%
23,45
4.173 USD
|
178
-0.2%
|
23,45
|
4.173 USD
|
|
|
2014-10-08 |
2014-10-06 |
V
Verkauf
|
CMEA Ventures VII LP
Large shareholder
|
6.931
-0.2%
23,45
162.497 USD
|
6.931
-0.2%
|
23,45
|
162.497 USD
|
|
|
2014-09-22 |
2014-09-19 |
K
Kauf
|
PROEHL GERALD T
Nicht geschäftsführender Verwaltungsratsmitglied
|
1.466
+inf%
21,75
31.885 USD
|
1.466
+inf%
|
21,75
|
31.885 USD
|
|
|
2014-09-08 |
2014-09-05 |
V
Verkauf
|
CMEA Ventures VII LP
Large shareholder
|
222
-0.2%
23,50
5.217 USD
|
222
-0.2%
|
23,50
|
5.217 USD
|
|
|
2014-09-08 |
2014-09-05 |
V
Verkauf
|
CMEA Ventures VII LP
Large shareholder
|
8.678
-0.2%
23,50
203.926 USD
|
8.678
-0.2%
|
23,50
|
203.926 USD
|
|
|
2014-09-08 |
2014-09-04 |
V
Verkauf
|
CMEA Ventures VII LP
Large shareholder
|
417
-0.4%
24,05
10.030 USD
|
417
-0.4%
|
24,05
|
10.030 USD
|
|
|
2014-09-08 |
2014-09-04 |
V
Verkauf
|
CMEA Ventures VII LP
Large shareholder
|
16.283
-0.4%
24,05
391.634 USD
|
16.283
-0.4%
|
24,05
|
391.634 USD
|
|
|
2014-09-04 |
2014-09-03 |
V
Verkauf
|
CMEA Ventures VII LP
Large shareholder
|
312
-0.3%
23,09
7.205 USD
|
312
-0.3%
|
23,09
|
7.205 USD
|
|
|
2014-09-04 |
2014-09-03 |
V
Verkauf
|
CMEA Ventures VII LP
Large shareholder
|
12.188
-0.3%
23,09
281.467 USD
|
12.188
-0.3%
|
23,09
|
281.467 USD
|
|
|
2014-09-04 |
2014-09-02 |
V
Verkauf
|
CMEA Ventures VII LP
Large shareholder
|
255
-0.3%
23,07
5.883 USD
|
255
-0.3%
|
23,07
|
5.883 USD
|
|
|
2014-09-04 |
2014-09-02 |
V
Verkauf
|
CMEA Ventures VII LP
Large shareholder
|
9.945
-0.3%
23,07
229.425 USD
|
9.945
-0.3%
|
23,07
|
229.425 USD
|
|
|
2014-09-03 |
2014-08-29 |
V
Verkauf
|
CMEA Ventures VII LP
Large shareholder
|
217
-0.2%
22,59
4.903 USD
|
217
-0.2%
|
22,59
|
4.903 USD
|
|
|
2014-09-03 |
2014-08-29 |
V
Verkauf
|
CMEA Ventures VII LP
Large shareholder
|
8.483
-0.2%
22,59
191.650 USD
|
8.483
-0.2%
|
22,59
|
191.650 USD
|
|
|
2014-08-29 |
2014-08-28 |
V
Verkauf
|
CMEA Ventures VII LP
Large shareholder
|
305
-0.3%
22,24
6.784 USD
|
305
-0.3%
|
22,24
|
6.784 USD
|
|
|
2014-08-29 |
2014-08-28 |
V
Verkauf
|
CMEA Ventures VII LP
Large shareholder
|
11.895
-0.3%
22,24
264.564 USD
|
11.895
-0.3%
|
22,24
|
264.564 USD
|
|
|
2014-08-29 |
2014-08-27 |
V
Verkauf
|
CMEA Ventures VII LP
Large shareholder
|
435
-0.5%
21,88
9.517 USD
|
435
-0.5%
|
21,88
|
9.517 USD
|
|
|
2014-08-29 |
2014-08-27 |
V
Verkauf
|
CMEA Ventures VII LP
Large shareholder
|
16.965
-0.5%
21,88
371.148 USD
|
16.965
-0.5%
|
21,88
|
371.148 USD
|
|
|
2014-08-28 |
2014-08-26 |
V
Verkauf
|
CMEA Ventures VII LP
Large shareholder
|
157
-0.2%
21,35
3.352 USD
|
157
-0.2%
|
21,35
|
3.352 USD
|
|
|
2014-08-28 |
2014-08-26 |
V
Verkauf
|
CMEA Ventures VII LP
Large shareholder
|
6.143
-0.2%
21,35
131.165 USD
|
6.143
-0.2%
|
21,35
|
131.165 USD
|
|
|
2014-08-27 |
2014-08-25 |
V
Verkauf
|
CMEA Ventures VII LP
Large shareholder
|
135
-0.1%
20,81
2.809 USD
|
135
-0.1%
|
20,81
|
2.809 USD
|
|
|
2014-08-27 |
2014-08-25 |
V
Verkauf
|
CMEA Ventures VII LP
Large shareholder
|
5.265
-0.1%
20,81
109.549 USD
|
5.265
-0.1%
|
20,81
|
109.549 USD
|
|
|
2014-08-26 |
2014-08-22 |
V
Verkauf
|
CMEA Ventures VII LP
Large shareholder
|
42
-0.0%
20,56
863 USD
|
42
-0.0%
|
20,56
|
863 USD
|
|
|
2014-08-26 |
2014-08-22 |
V
Verkauf
|
CMEA Ventures VII LP
Large shareholder
|
1.658
-0.0%
20,56
34.085 USD
|
1.658
-0.0%
|
20,56
|
34.085 USD
|
|
|
2014-07-16 |
2014-07-16 |
K
Kauf
|
GREER R SCOTT
Nicht geschäftsführender Verwaltungsratsmitglied
|
5.190
+259.5%
19,25
99.908 USD
|
5.190
+259.5%
|
19,25
|
99.908 USD
|
|
|
2014-09-09 |
2014-05-14 |
V
Verkauf
|
Thomas, McNerney & Partners II L.P.
Large shareholder
|
12.400
-0.2%
20,60
255.415 USD
|
12.400
-0.2%
|
20,60
|
255.415 USD
|
|
|
2014-09-09 |
2014-05-14 |
V
Verkauf
|
Zisson Alex
Nicht geschäftsführender Verwaltungsratsmitglied
Large shareholder
|
12.400
-0.2%
20,60
255.415 USD
|
12.400
-0.2%
|
20,60
|
255.415 USD
|
|
|
2014-10-01 |
2014-02-10 |
K
Kauf
|
Thomas, McNerney & Partners II, LLC
Nicht geschäftsführender Verwaltungsratsmitglied
Large shareholder
|
82.475
+1.6%
12,00
989.700 USD
|
82.475
+1.6%
|
12,00
|
989.700 USD
|
|
|
2014-02-12 |
2014-02-10 |
K
Kauf
|
CMEA Ventures VII LP
Large shareholder
|
2.688
+2.9%
12,00
32.256 USD
|
2.688
+2.9%
|
12,00
|
32.256 USD
|
|
